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ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:38 AM EDT

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Showing 241–264 of 283 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Injury Foot Clear all
Completed Phase 1 Interventional

ExpressGraft-C9T1 Skin Tissue as a Treatment of Diabetic Foot Ulcers

NCT02657876
View directory record Official record
Conditions
Diabetes, Diabetic Foot Ulcer, Non-healing Wound
Interventions
ExpressGraft-C9T1 Skin Tissue
Biological
Lead sponsor
Stratatech, a Mallinckrodt Company
Industry
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 15, 2019 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional

Nutritional Supplements and Foot Surgery

NCT05522179
View directory record Official record
Conditions
Foot Injuries and Disorders
Interventions
NutraHeal, NutraHeal Plus
Dietary Supplement
Lead sponsor
NutraHeal
Industry
Eligibility
20 Years to 80 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
3
States / cities
Altoona, Pennsylvania • Ebensburg, Pennsylvania • State College, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Oct 21, 2026, 5:38 AM EDT
Withdrawn Not applicable Interventional

Waterproof Casting Versus Standard Casting for Short Leg Walking Casts

NCT04961957
View directory record Official record
Conditions
Ankle Fractures, Foot Fracture, Ankle Sprains, Foot Sprain, Toe-walking, Tendonitis of Foot, Apophysitis; Juvenile
Interventions
Waterproof padding, Non-waterproof padding
Device
Lead sponsor
West Virginia University
Other
Eligibility
5 Years to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Oct 21, 2026, 5:38 AM EDT
Active, not recruiting Not applicable Interventional

Ankle Instability Using Foot Intensive Rehabilitation

NCT04493645
View directory record Official record
Conditions
Ankle Injuries, Ankle Sprains
Interventions
Standard of Care Rehabilitation (SOC), Foot Intensive Rehabilitation (FIRE)
Behavioral
Lead sponsor
Matthew Hoch
Other
Eligibility
18 Years to 44 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 21, 2026, 5:38 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers

Outpatient Treatment of Gram Positive Wound Infections in the Diabetic Foot: A Pharmaco-economic Comparison of Daptomycin vs. Vancomycin Based Regimens

NCT01133600
View directory record Official record
Conditions
Diabetic Foot
Interventions
Cubicin, Vancomycin
Drug
Lead sponsor
Clinical Alliance for Research & Education - Infectious Diseases, LLC.
Other
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
2
States / cities
Annandale, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 10, 2013 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional

Hallux Limitus Treated With Dynamic Splinting: A Randomized, Controlled Trial

NCT00717691
View directory record Official record
Conditions
Hallux Limitus
Interventions
Metatarsophalangeal Extension Dynasplint System, Standard of Care
Device · Other
Lead sponsor
Dynasplint Systems, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
2
States / cities
Jonesboro, Georgia • Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated Apr 30, 2012 · Synced Oct 21, 2026, 5:38 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Diabetic Foot Ulcer and Wound Infection

NCT03827902
View directory record Official record
Conditions
Diabetes Complications, Diabetes, Diabetic Foot Ulcer, Wound Infection
Interventions
Telcare 2.0 BGM
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 6, 2020 · Synced Oct 21, 2026, 5:38 AM EDT
Recruiting Not applicable Interventional

Evaluating a Lifestyle Intervention to Prevent Recurrence of Diabetic Foot Ulcers

NCT06487780
View directory record Official record
Conditions
Diabetic Foot, Diabetic Foot Ulcer, Foot Ulcer, Diabetic, Foot Wound
Interventions
Lifestyle-focused Occupational Therapy Intervention, Education
Behavioral · Other
Lead sponsor
University of Southern California
Other
Eligibility
21 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
3
States / cities
Downey, California • Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 22, 2025 · Synced Oct 21, 2026, 5:38 AM EDT
Active, not recruiting Not applicable Interventional

Comparing Functional Outcomes in Individuals Using Micro-processor Controlled Orthosis Versus Stance Control Orthosis

NCT02089880
View directory record Official record
Conditions
Spinal Cord Injuries, Poliomyelitis, Post-polio Syndrome, Arthritis, Lower Motor Neurone Lesion
Interventions
C-brace, Stance control orthosis
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 1, 2025 · Synced Oct 21, 2026, 5:38 AM EDT
Completed No phase listed Observational

Diabetic Foot Ulcers Microbiome and Pathogen Identification

NCT05556954
View directory record Official record
Conditions
Foot Ulcer, Diabetes Mellitus, Wound
Interventions
Wound debridement
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 75 Years
Enrollment
103 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 19, 2025 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Outcomes After Treatment With RestrataTM Wound Matrix in Diabetic Foot Ulcers (DFU)

NCT03312595
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Restrata TM Wound Matrix
Device
Lead sponsor
Acera Surgical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
5
States / cities
Phoenix, Arizona • Tucson, Arizona • Fresno, California + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Phase 2 Interventional

Topical PluroGel N for the Treatment of Mildly Infected Diabetic Foot Ulcers

NCT02091596
View directory record Official record
Conditions
Diabetic Foot Ulcer, Infection
Interventions
PluroGel N, PluroGel
Drug
Lead sponsor
PluroGen Therapeutics, Inc
Industry
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
15
States / cities
Phoenix, Arizona • Los Angeles, California • Oakland, California + 8 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2014 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional

CGM and DFU Healing Post-discharge

NCT06054659
View directory record Official record
Conditions
Diabetic Foot, Diabetes Type 2 With Diabetic Ulcer of Toe, Skin Breakdown
Interventions
Real Time Continuous Glucose Monitoring (rt-CGM), Fingerstick blood glucose (FBG) monitoring, Diabetes Education
Device · Other · Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Atlanta, Georgia • Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 21, 2026, 5:38 AM EDT
Not listed No phase listed Observational

DETEC® pH Point of Care Wound Diagnostic Test

NCT04614038
View directory record Official record
Conditions
Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer, Wound, Non-Healed
Interventions
DETEC® pH
Diagnostic Test
Lead sponsor
Progenitec Inc.
Industry
Eligibility
21 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Lake Success, New York • Arlington, Texas
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional

A Dual-center Study Evaluating Clinical Acceptance of a NPWT Wound Care System

NCT04593693
View directory record Official record
Conditions
Diabetic Foot Ulcer, Pressure Injury, Pressure Ulcer, Surgical Wound, Acute Wound, Traumatic Wound, Dehiscence, Edema
Interventions
Invia Motion Endure NPWT system
Device
Lead sponsor
Medela AG
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Augusta, Georgia • Austell, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 24, 2021 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Phase 2 Interventional

A Clinical Study of the Safety and Efficacy of MEBO Wound Ointment in Subjects With Diabetic Foot Ulcers

NCT01070433
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
MEBO Wound Ointment (MEBO), Standard of Care
Drug · Other
Lead sponsor
Skingenix, Inc.
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
9
States / cities
Phoenix, Arizona • Castro Valley, California • Encinitas, California + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 6, 2025 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional

NeoPatch Used as Adjunct in Foot and Ankle Tendon Surgery

NCT03307499
View directory record Official record
Conditions
Tendinopathy, Tendon Tear, Tendon Injuries, Foot Ankle Injuries
Interventions
NeoPatch
Other
Lead sponsor
CryoLife, Inc.
Industry
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Sycamore, Illinois
Source: ClinicalTrials.gov public record
Updated May 24, 2019 · Synced Oct 21, 2026, 5:38 AM EDT
Recruiting Not applicable Interventional

Effect of Custom Dynamic Orthoses on Forefoot Loading

NCT06710119
View directory record Official record
Conditions
Lower Extremity Injuries
Interventions
Visual Feedback
Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Iowa City, Iowa • Everett, Washington
Source: ClinicalTrials.gov public record
Updated Oct 19, 2026 · Synced Oct 21, 2026, 5:38 AM EDT
Active, not recruiting No phase listed Observational

Real-World Effectiveness of Amniotic Membrane Allografts Versus Standard Wound Care in DFU, VLU, and PU

NCT07223281
View directory record Official record
Conditions
Diabetic Foot Ulcer (DFU), Venous Leg Ulcers (VLUs), Pressure Ulcers, Bedsores, Decubitus Ulcer
Interventions
Not listed
Lead sponsor
Legacy Medical Consultants
Industry
Eligibility
18 Years and older
Enrollment
2,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
4
States / cities
Colorado Springs, Colorado • Clinton Township, Michigan • Tulsa, Oklahoma + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional

DermACELL AWM® in Chronic Wagner Grade 3/4 Diabetic Foot Ulcers

NCT03044132
View directory record Official record
Conditions
Diabetic Foot Ulcer, Lower Extremity Wound
Interventions
DermACELL AWM
Other
Lead sponsor
LifeNet Health
Industry
Eligibility
21 Years to 85 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Fresno, California • Rocky Mount, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 6, 2019 · Synced Oct 21, 2026, 5:38 AM EDT
Not yet recruiting Not applicable Interventional

Evaluating the Efficacy of FoundationDRS Solo in Addition to Standard of Care for the Treatment of Non-healing Diabetic Foot Ulcers

NCT07290673
View directory record Official record
Conditions
Diabetic Foot Ulcer (DFU)
Interventions
FoundationDRS Solo, Standard of Care
Other
Lead sponsor
Samaritan Biologics
Industry
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Hollywood, Florida
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Oct 21, 2026, 5:38 AM EDT
Terminated No phase listed Observational

Adjunct Collection of Additional Biorepository Data From Patients Enrolled in Diabetic Foot Consortium (DFC) Trials

NCT05092620
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
5
States / cities
Palo Alto, California • San Francisco, California • Miami, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Results available

Electrical Stimulation to Accelerate Wound Healing

NCT03821675
View directory record Official record
Conditions
Diabetes, Diabetic Foot Ulcer, Peripheral Neuropathy, Peripheral Arterial Disease
Interventions
Electrical Stimulation - Active, Electrical Stimulation - Sham
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 85 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Results available

Evaluation of the Effects of HP828-101 Versus Standard of Care in the Management of Partial or Full Thickness Wounds

NCT00971048
View directory record Official record
Conditions
Diabetic Foot Ulcers, Pressure Ulcers
Interventions
HP828-101, Hydrogel/Hydrocolloid
Device
Lead sponsor
Healthpoint
Industry
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
11
States / cities
Bakersfield, California • Chula Vista, California • Fresno, California + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 27, 2014 · Synced Oct 21, 2026, 5:38 AM EDT