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ClinicalTrials.gov public records Last synced Oct 20, 2026, 3:08 PM EDT

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Showing 169–192 of 283 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Injury Foot Clear all
Not listed Not applicable Interventional

Prospective, Multicenter, RCT of the Tenex Ultrasound System

NCT06137222
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Tenex TXB MicroTip Ultrasound system plus SOC, Standard of Care for diabetic foot ulcer
Device · Other
Lead sponsor
Tenex Health Inc.
Industry
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Mobile, Alabama • St. George, Utah
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 20, 2026, 3:08 PM EDT
Completed Not applicable Interventional

Does Blood Vessel Vasodilation, Caused by Focal Infiltration of Lidocaine Cause Temporary Nerve Functional Recovery for Patients with Common Peroneal Nerve Injury or Entrapment: Testing the 'Phoenix Sign' Effect Between Lidocaine (a Common Local Anesthetic) and Papaverine, a Know Vasodilator

NCT06637046
View directory record Official record
Conditions
Drop Foot
Interventions
Diagnostic procedures, Lidocaine HCl
Diagnostic Test
Lead sponsor
Stephen Barrett
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 20, 2026, 3:08 PM EDT
Completed Not applicable Interventional Results available

Low-Level Laser Therapy for Plantar Fasciitis

NCT05763381
View directory record Official record
Conditions
Plantar Fascitis
Interventions
Photobiomodulation Therapy (PBMT), Sham-Photobiomodualtion Therapy (Sham-PBMT)
Device
Lead sponsor
The Geneva Foundation
Other
Eligibility
18 Years to 64 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Oct 20, 2026, 3:08 PM EDT
Terminated Not applicable Interventional Results available

A Comparison of an Investigational Dressing to Tegaderm Matrix Wound Dressing in the Management of Diabetic Foot Ulcers

NCT01013792
View directory record Official record
Conditions
Foot Ulcer, Diabetic
Interventions
Wound Dressing
Device
Lead sponsor
Solventum US LLC
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
6
States / cities
Montgomery, Alabama • Castro Valley, California • Bay Pines, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Oct 20, 2026, 3:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Non-Invasive Assessment of Wound Healing With Optical Methods

NCT00578604
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
diffuse near infrared spectroscopy measurements
Device
Lead sponsor
Drexel University College of Medicine
Other
Eligibility
18 Years to 65 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 30, 2017 · Synced Oct 20, 2026, 3:08 PM EDT
Completed Not applicable Interventional

Quasi-Randomized Evaluation of the UCLA Next Day Clinic (NDC)

NCT06526884
View directory record Official record
Conditions
Pneumonia, Syncope, Congestive Heart Failure, Cellulitis, Pyelonephritis, AKI - Acute Kidney Injury, Diabetic Foot Infection, Osteomyelitis
Interventions
Next Day Clinic
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
570 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 20, 2026, 3:08 PM EDT
Completed Not applicable Interventional Results available

Efficacy, Safety and Economic Benefits of Topical Wound Oxygen Therapy in the Treatment of Chronic Diabetic Foot Ulcers

NCT02326337
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
TWO2 Device, Placebo Device
Device
Lead sponsor
AOTI Ltd.
Industry
Eligibility
18 Years to 89 Years
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
10
States / cities
Phoenix, Arizona • Vacaville, California • Washington D.C., District of Columbia + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Oct 20, 2026, 3:08 PM EDT
Active, not recruiting Not applicable Interventional

C-Brace II Spinal Cord Injury

NCT03930056
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
C-Brace II, Traditional Care KAFO intervention
Device
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Oct 20, 2026, 3:08 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

A Comparison of Stainless Steel and Bioabsorbable Screw Fixation of Lisfranc Foot Injuries

NCT00985023
View directory record Official record
Conditions
Unstable Lisfranc Fracture-dislocations of the Midfoot
Interventions
Steel screw fixation of Lisfranc fracture-dislocation., Absorbable screw fixation of Lisfranc fracture-dislocations.
Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2016
U.S. locations
2
States / cities
Media, Pennsylvania • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 18, 2017 · Synced Oct 20, 2026, 3:08 PM EDT
Terminated Not applicable Interventional

Derm-Maxx in Patients With Diabetic Foot Ulcers Unresponsive to Standard of Care Treatment Alone

NCT06455475
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Derm-Maxx
Other
Lead sponsor
Capsicure, LLC
Network
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
11
States / cities
Athens, Alabama • Encino, California • Hollywood, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 20, 2026, 3:08 PM EDT
Not listed No phase listed Observational

Long-term Safety and Effectiveness of AUGMENT® Bone Graft Compared to Autologous Bone Graft

NCT02879149
View directory record Official record
Conditions
Ankle and Hindfoot Arthrodesis
Interventions
AUGMENT® Bone Graft, Standard of Care
Device · Procedure
Lead sponsor
BioMimetic Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
21
States / cities
Tucson, Arizona • Capitola, California • San Francisco, California + 18 more
Source: ClinicalTrials.gov public record
Updated Mar 27, 2018 · Synced Oct 20, 2026, 3:08 PM EDT
Completed Phase 2 Interventional Results available

Phase 2a Multi-Center Prospective, Randomized Trial to Evaluate the Safety & Efficacy of Topical PEP-TISSEEL for Diabetic Foot Ulcers (DFU)

NCT06319287
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
PEP (Purified Exosome Product) / TISSEEL
Biological
Lead sponsor
Rion Inc.
Industry
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Blue Ash, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 20, 2026, 3:08 PM EDT
Terminated Phase 4 Interventional Results available

Use of INTEGRA™ Flowable Wound Matrix to Manage Diabetic Foot Ulcers

NCT01108263
View directory record Official record
Conditions
Diabetes, Foot Ulcer
Interventions
INTEGRA™ Flowable Matrix (Collagen)
Drug
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Mar 17, 2014 · Synced Oct 20, 2026, 3:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Triage-Based Application of OFAR on the Number of Radiographs Ordered

NCT01779804
View directory record Official record
Conditions
Ankle Injuries, Foot Injuries
Interventions
OFAR
Procedure
Lead sponsor
Lehigh Valley Hospital
Other
Eligibility
16 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Allentown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 8, 2016 · Synced Oct 20, 2026, 3:08 PM EDT
Recruiting Not applicable Interventional

Study of Miro3D Wound Matrix for Healing Wounds and Ulcers in Outpatient Care

NCT06939673
View directory record Official record
Conditions
Diabetic Foot Ulcers (DFUs), Venous Leg Ulcers (VLUs), Pressure Ulcers, Surgical Wound Dehiscence (SWD), Chronic Wounds, Undermined and Tunneling Wounds
Interventions
Acellular Porcine-Derived Wound Matrix
Device
Lead sponsor
Reprise Biomedical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Coconut Creek, Florida • Tamarac, Florida
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Oct 20, 2026, 3:08 PM EDT
Terminated Not applicable Interventional

Effectiveness of AutoloGel Therapy in Diabetic Foot Ulcers

NCT01816633
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
AutoloGel
Device
Lead sponsor
Cytomedix
Industry
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
2
States / cities
Arcadia, California • Cumming, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 21, 2016 · Synced Oct 20, 2026, 3:08 PM EDT
Completed Phase 4 Interventional

Exparel Use in Peripheral Nerve Blocks and Local Infiltration for Foot and Ankle Surgery

NCT05494645
View directory record Official record
Conditions
Pain, Postoperative, Pain, Acute Postoperative, Ankle Fractures, Ankle Injuries and Disorders
Interventions
Exparel, Peripheral Nerve Block
Drug
Lead sponsor
St. Luke's Hospital, Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Bethlehem, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 20, 2026, 3:08 PM EDT
Recruiting No phase listed Observational

Correlating Multispectral Near-Infrared Imaging to Standard Vascular Diagnostics

NCT06899113
View directory record Official record
Conditions
Vascular Disease, Peripheral, Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer)
Interventions
Not listed
Lead sponsor
MIMOSA Diagnostics Inc.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Timeline
2025
U.S. locations
1
States / cities
Lake Success, New York
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Oct 20, 2026, 3:08 PM EDT
Recruiting Not applicable Interventional

Comprehensive Assistance and Resources for Effective Diabetic Foot Navigation

NCT07223268
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
CARE-D-Foot-Nav, Standard of care
Other
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 31, 2025 · Synced Oct 20, 2026, 3:08 PM EDT
Terminated Phase 4 Interventional

RESPOND Restoring Equilibrium and Wound Stimulation to Promote Healing Of Non-healing DFUs

NCT01608776
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
MIST Therapy, SOC - Standard of Care
Device · Other
Lead sponsor
Celleration, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 8, 2014 · Synced Oct 20, 2026, 3:08 PM EDT
Completed Not applicable Interventional Results available

Sous Vide Rewarming for Frostbitten Extremities

NCT04633174
View directory record Official record
Conditions
Frostbite, Frostbite of Hand, Frostbite of Foot
Interventions
Sous Vide Device (SVD)
Device
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
Not listed
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Oct 20, 2026, 3:08 PM EDT
Completed Not applicable Interventional

Online Wound Electronic Medical Record (OWEMR) to Decrease Amputations in Diabetics

NCT01371318
View directory record Official record
Conditions
Wounds, Diabetes Complications, Diabetic Foot, Foot Ulcer
Interventions
Online Wound Electronic Medical Record
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
1,609 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
13
States / cities
Phoenix, Arizona • Tuscon, Arizona • Pomona, California + 8 more
Source: ClinicalTrials.gov public record
Updated Dec 31, 2014 · Synced Oct 20, 2026, 3:08 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Evaluation of Topical Wound Oxygen (two2) Therapy

NCT00871312
View directory record Official record
Conditions
Diabetic Ulcer
Interventions
Topical wound oxygen therapy, Topical wound oxygen Placebo
Device
Lead sponsor
AOTI Ltd.
Industry
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jan 10, 2014 · Synced Oct 20, 2026, 3:08 PM EDT
Not listed Not applicable Interventional

Effectiveness of Vaporous Hyperoxia Therapy (VHT) in the Treatment of Chronic Diabetic Foot Ulcers

NCT04210609
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Vaporous Hyperoxia Therapy
Device
Lead sponsor
Vaporox
Industry
Eligibility
18 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
3
States / cities
Castle Rock, Colorado • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 11, 2021 · Synced Oct 20, 2026, 3:08 PM EDT