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Showing 1–24 of 572 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Injury of Musculoskeletal System Clear all
Completed No phase listed Observational Accepts healthy volunteers

Evaluating Muscle Function After Ankle Surgery

NCT00060970
View directory record Official record
Conditions
Muscle Atrophy, Muscle Weakness, Fractures
Interventions
Physical Therapy
Procedure
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1995 – 2000
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Sep 9, 2026, 5:35 AM EDT
Completed Phase 2 Interventional

Healing With Venlafaxine After Injury (HELP)

NCT01716377
View directory record Official record
Conditions
Neck Pain
Interventions
Venlafaxine
Drug
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
3
States / cities
Grand Rapids, Michigan • Rochester, New York • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 12, 2017 · Synced Sep 9, 2026, 5:35 AM EDT
Recruiting Not applicable Interventional

Operant Conditioning of Spinal Reflexes Training System--Reflex Operant Down Conditioning

NCT05094362
View directory record Official record
Conditions
Spinal Cord Injuries, Neurological Injury, Paralysis, Spasticity, Muscle
Interventions
Spinal Reflex Operant Down Conditioning
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Sep 9, 2026, 5:35 AM EDT
Completed Phase 4 Interventional Results available

Antiepileptic Drugs and Osteoporotic Prevention Trial

NCT00869622
View directory record Official record
Conditions
Epilepsy, Bone Loss, Osteoporosis, Fractures
Interventions
Risedronate, Placebo + Calcium and Vitamin D
Drug
Lead sponsor
Boston VA Research Institute, Inc.
Other
Eligibility
18 Years to 85 Years · Male only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 23, 2015 · Synced Sep 9, 2026, 5:35 AM EDT
Recruiting Phase 4 Interventional

Efficacy Bioinductive Implant for Tennis Elbow (Lateral Epicondylitis)

NCT03718637
View directory record Official record
Conditions
Tennis Elbow, Lateral Epicondylitis
Interventions
Smith & Nephew Bioinductive Implant, Lateral Epicondylectomy, Ultrasound Imaging
Biological · Procedure · Radiation
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older · Male only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Sep 9, 2026, 5:35 AM EDT
Completed No phase listed Observational

Healthy Hip Study: Conservative Management for Pre-arthritic Hip Disorders

NCT04069507
View directory record Official record
Conditions
Femoroacetabular Impingement, Acetabular Dysplasia, Acetabular Labrum Tear, Hip Pain, Rehabilitation
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
15 Years to 40 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Sep 9, 2026, 5:35 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Platelet Rich Plasma for Musculoskeletal Conditions

NCT07231471
View directory record Official record
Conditions
Osteoarthritis (OA), Osteoarthritis (OA) of the Knee, Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Shoulder, Osteoarthritis Ankle, Elbow Osteoarthritis, Epicondylitis of the Elbow, Plantar Fasciitis of Both Feet, Tendinopathy
Interventions
Platelet Rich Plasma Injection, Platelet Rich Plasma Preparation
Biological · Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2035
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 9, 2026, 5:35 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Development of a Model of Shoulder Pain Following Spinal Cord Injury

NCT03137394
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Observation
Other
Lead sponsor
Drexel University
Other
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
2
States / cities
Gwynn Oak, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 30, 2022 · Synced Sep 9, 2026, 5:35 AM EDT
Completed No phase listed Observational Results available

Performance-Enhancing Effects of Platelet-Rich Plasma (PRP) Injections

NCT01200875
View directory record Official record
Conditions
Tendinopathy, Rheumatic Diseases
Interventions
Ultrasound-guided platelet-rich-plasma (PRP) injection, Platelet-Rich Plasma (PRP)
Procedure
Lead sponsor
Stanford University
Other
Eligibility
Not listed
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 5, 2018 · Synced Sep 9, 2026, 5:35 AM EDT
Not yet recruiting Not applicable Interventional

Synovial Fluid Withdrawal or PRP Injection For Acute ACL Tears and Cytokines

NCT07142369
View directory record Official record
Conditions
Posttraumatic Osteoarthritis, Anterior Cruciate Ligament (ACL) Rupture
Interventions
Synovial Fluid withdrawal at the preoperative clinic visit, Platelet-Rich Plasma (PRP) preparation and injection, Synovial fluid withdrawal at the time of surgery, 3mL synovial fluid withdrawn at the preoperative visit
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 50 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 9, 2026, 5:35 AM EDT
Completed No phase listed Observational

Patient Outcomes Evaluation of the EBI Vuelock™ Anterior Cervical Plate System

NCT00726128
View directory record Official record
Conditions
Trauma, Tumor, Pseudarthrosis, Scoliosis, Degenerative Disc Disease
Interventions
VueLock™ Anterior Cervical Plate
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
Not listed
Enrollment
371 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2009
U.S. locations
4
States / cities
Palo Alto, California • San Diego, California • Avon, Indiana + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 23, 2020 · Synced Sep 9, 2026, 5:35 AM EDT
Completed Not applicable Interventional

Neurohormonal Benefits of Exercise in Fibromyalgia and PTSD

NCT03236467
View directory record Official record
Conditions
FM and PTSD
Interventions
Progressive Exercise Training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 60 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 2, 2022 · Synced Sep 9, 2026, 5:35 AM EDT
Not listed Phase 1Phase 2 Interventional

Evaluation of EpiBone-CMF for Mandibular Ramus Reconstruction

NCT03678467
View directory record Official record
Conditions
Mandible Tumor, Mandibular Injuries, Mandible; Deformity
Interventions
EB-CMF
Combination Product
Lead sponsor
Epibone, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
3
States / cities
San Francisco, California • Cleveland, Ohio • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 26, 2022 · Synced Sep 9, 2026, 5:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mind-Body Conditioning Course for University Dance Students

NCT06925503
View directory record Official record
Conditions
Perceived Stress, Student Burnout, Resilience, Musculoskeletal Injury, Musculoskeletal Abnormalities
Interventions
Mind-Body Conditioning Course
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 9, 2026, 5:35 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of Lumbosacral Joint Mobilization/Manipulation on Lower Extremity Muscle Neuromuscular Response

NCT00601341
View directory record Official record
Conditions
Knee Pain, Hip Pain, Ankle Pain, Lumbopelvic Pain
Interventions
lumbosacral joint manipulation, lumbar passive range of motion, No active intervention
Other
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 50 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2009
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 23, 2010 · Synced Sep 9, 2026, 5:35 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Efficacy of Lidocaine Patch in Acute Musculoskeletal Pain in the Emergency Department

NCT03571737
View directory record Official record
Conditions
Acute Musculoskeletal Disease, Sprains, Sprains and Strains, Injuries, Emergencies, Trauma, Acute Pain
Interventions
Ibuprofen, Lidocaine Patch 4%
Drug
Lead sponsor
East Carolina University
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 24, 2024 · Synced Sep 9, 2026, 5:35 AM EDT
Terminated Phase 2 Interventional

Statin Monotherapy for Treatment of Endocrine Metabolic Disease Risk

NCT03113994
View directory record Official record
Conditions
Spinal Cord Injuries, Osteoporosis, Metabolic Syndrome
Interventions
Rosuvastatin Calcium, Placebo Oral Tablet, Coenzyme Q10, Calcium Carbonate, Vitamin D
Drug · Dietary Supplement
Lead sponsor
Dr. B. Catharine. Craven
Other
Eligibility
18 Years to 60 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 9, 2026, 5:35 AM EDT
Not listed Not applicable Interventional

Treatment of Lateral Epicondylitis With a Percussive Therapy Device

NCT05723809
View directory record Official record
Conditions
Tennis Elbow
Interventions
Percussive Therapy Device, Physical Therapy
Device · Behavioral
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 12, 2023 · Synced Sep 9, 2026, 5:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Protective Brace to Prevent Hand and Arm Injuries

NCT00074893
View directory record Official record
Conditions
Cumulative Trauma Disorders, Carpal Tunnel Syndrome
Interventions
piezoelectric wrist brace
Device
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
NIH
Eligibility
21 Years to 55 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2004
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 7, 2006 · Synced Sep 9, 2026, 5:35 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Sequencing on Outcome Measures

NCT06445491
View directory record Official record
Conditions
Muscle Weakness
Interventions
Control order, Randomized sequence
Other
Lead sponsor
Louisiana State University Health Sciences Center Shreveport
Other
Eligibility
18 Years to 57 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Shreveport, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Sep 9, 2026, 5:35 AM EDT
Recruiting Not applicable Interventional

Absorbable vs Non-Absorbable Sutures for Hip Capsular Closure

NCT06845735
View directory record Official record
Conditions
Labrum Injury of the Hip Joint, Hip Arthroscopy, Femoroacetabular Impingement Syndrome
Interventions
Non-Absorbable Sutures, Absorbable Suture
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 9, 2026, 5:35 AM EDT
Recruiting No phase listed Observational

JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction

NCT06883396
View directory record Official record
Conditions
Patellar Dislocation, Recurrent, Patellar Dislocation, Patellar Instability, Patellofemoral Dislocation, Patellofemoral Joint Dislocation, Patellofemoral Disorder
Interventions
Medial Patellofemoral Ligament (MPFL) Reconstruction
Procedure
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
10 Years to 35 Years
Enrollment
850 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
16
States / cities
Redwood City, California • Gainesville, Florida • Chicago, Illinois + 10 more
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Sep 9, 2026, 5:35 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Study of Effects of Age and Hyperkyphosis on Spine Motion and Loading

NCT03008902
View directory record Official record
Conditions
Kyphosis, Vertebral Fracture
Interventions
Near-infrared passive motion capture recording
Procedure
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 3, 2018 · Synced Sep 9, 2026, 5:35 AM EDT
Completed Not applicable Interventional Results available

A Pilot Study of Switching From One Pain Medication to Another (Opioid Rotation)

NCT00580294
View directory record Official record
Conditions
Pain
Interventions
Oxymorphone
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 2, 2016 · Synced Sep 9, 2026, 5:35 AM EDT