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ClinicalTrials.gov public records Last synced Oct 21, 2026, 7:35 PM EDT

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Showing 1–24 of 1,027 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Insomnia Clear all
Completed Not applicable Interventional

The Effect of Family History on Insomnia During Sobriety in Alcoholics

NCT01603381
View directory record Official record
Conditions
Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I)
Behavioral
Lead sponsor
Corporal Michael J. Crescenz VA Medical Center
Federal
Eligibility
18 Years to 65 Years · Male only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 4, 2016 · Synced Oct 21, 2026, 7:35 PM EDT
Recruiting Not applicable Interventional

Transcutaneous Auricular Vagus Nerve Stimulation for Insomnia in Survivors of Childhood Acute Lymphoblastic Leukemia

NCT07191119
View directory record Official record
Conditions
Survivor of Childhood Cancer, Insomnia, Acute Lymphoblastic Leukemia (ALL)
Interventions
Soterix tVNS device, Soterix tVNS device (sham programmed), Sleep Quality, Neurocognitive and mental health outcomes
Device · Behavioral
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
20 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 21, 2026, 7:35 PM EDT
Completed Phase 2 Interventional

Sleep and Ventricular Arrhythmias Study

NCT02232204
View directory record Official record
Conditions
Cardiac Arrhythmia, Implantable Defibrillator User, Insomnia
Interventions
CBT for Insomnia in ICD Patients (CBT-I-ICD)
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 5, 2014 · Synced Oct 21, 2026, 7:35 PM EDT
Recruiting Not applicable Interventional

A Hybrid Effectiveness Implementation Trial Evaluating Behavioral Treatments for Insomnia for Socioeconomically Disadvantaged Adults in Primary Care

NCT05759065
View directory record Official record
Conditions
Insomnia
Interventions
Tele-Brief Behavioral Treatment for Insomnia, Tele-Cognitive-Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 21, 2026, 7:35 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Cereset Research For Chronic Nausea

NCT05229107
View directory record Official record
Conditions
Nausea, Gastroparesis, Stress, Anxiety, Hyperarousal, Quality of Life, Vomiting, Heart Rate Variability
Interventions
Cereset Research
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Oct 21, 2026, 7:35 PM EDT
Completed Phase 3 Interventional

6-Month Chronic Efficacy & Safety Study of Eszopiclone in Adult Subjects With Primary Insomnia

NCT00352144
View directory record Official record
Conditions
Primary Insomnia
Interventions
Eszopiclone, Placebo
Drug
Lead sponsor
Sumitomo Pharma America, Inc.
Industry
Eligibility
21 Years to 64 Years
Enrollment
830 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
58
States / cities
Birmingham, Alabama • Huntsville, Alabama • Phoenix, Arizona + 55 more
Source: ClinicalTrials.gov public record
Updated Feb 22, 2012 · Synced Oct 21, 2026, 7:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep in Osteoarthritis Project

NCT00592449
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders, Osteoarthritis
Interventions
Cognitive behavioral therapy (CBT) for insomnia, Behavioral desensitization treatment for insomnia
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
35 Years to 100 Years
Enrollment
209 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 23, 2019 · Synced Oct 21, 2026, 7:35 PM EDT
Completed Not applicable Interventional

Behavioral Insomnia Therapy in Primary Care

NCT00105872
View directory record Official record
Conditions
Insomnia, Primary Insomnia, Secondary Insomnia
Interventions
Cognitive-Behavioral Therapy
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2006
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 7, 2015 · Synced Oct 21, 2026, 7:35 PM EDT
Completed Phase 2 Interventional

A Polysomnographic Study to Compare the Efficacy of Gastric Retentive Zaleplon Accordion Pill to Placebo in Subjects With Insomnia

NCT01277107
View directory record Official record
Conditions
Insomnia
Interventions
Zaleplon AP formulation, Placebo capsule
Drug
Lead sponsor
Intec Pharma Ltd.
Industry
Eligibility
18 Years to 65 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
5
States / cities
San Diego, California • Miami, Florida • Pembroke Pines, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2014 · Synced Oct 21, 2026, 7:35 PM EDT
Not listed Not applicable Interventional

e-Pharmacovigilance II - Surveillance for Safety and Effectiveness - Calling for Earlier Detection of Adverse Reactions

NCT02087293
View directory record Official record
Conditions
Diabetes, Depression, Insomnia, Hypertension
Interventions
Intervention arm - automated call and phone-based pharmacist counseling
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years and older
Enrollment
38,400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 4, 2015 · Synced Oct 21, 2026, 7:35 PM EDT
Not yet recruiting Not applicable Interventional

The Impact of Brief Behavioral Treatment for Insomnia Versus Brief Mindfulness Treatment on Cognition and Sleep Health in Adults (Age 50+) With HIV

NCT07272863
View directory record Official record
Conditions
Insomnia, Cognition, Aging, HIV
Interventions
BBTI, BMT
Behavioral
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
50 Years to 99 Years
Enrollment
214 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
Birmingham, Alabama • Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 21, 2026, 7:35 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

UCLA REST Study (REsearch on Sleep Techniques)

NCT05576090
View directory record Official record
Conditions
Sleep Disturbance, Inflammation, Psychosocial Functioning
Interventions
Mindfulness Meditation, Sleep Education
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 22 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 21, 2026, 7:35 PM EDT
Completed Phase 3 Interventional Results available

Long Term Safety Study of Study Drug (Eszopiclone) in Children and Adolescents With ADHD -Associated Insomnia

NCT00857220
View directory record Official record
Conditions
Insomnia, Attention Deficit Hyperactivity Disorder
Interventions
eszopiclone
Drug
Lead sponsor
Sumitomo Pharma America, Inc.
Industry
Eligibility
6 Years to 17 Years
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
89
States / cities
Tucson, Arizona • Little Rock, Arkansas • Carson, California + 70 more
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Oct 21, 2026, 7:35 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Nextsense Brain-sensing Buds Study

NCT06602960
View directory record Official record
Conditions
Sleep, Sleep Quality, Sleepiness, Daytime, Technology
Interventions
Accurate Sleep Data Feedback, Inflated Sleep Data Feedback, Deflated Sleep Data Feedback, Accurate Sleep Data Feedback + Sleep-related Educational Information
Behavioral
Lead sponsor
NextSense, Inc.
Industry
Eligibility
25 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 18, 2025 · Synced Oct 21, 2026, 7:35 PM EDT
Completed No phase listed Observational

To Study the Prevalence of Insomnia in Geriatric COPD Patients Who Are Enrolled in a Pulmonary Rehabilitation Program.

NCT00346554
View directory record Official record
Conditions
COPD, Sleep Disorders
Interventions
Not listed
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
60 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 4, 2014 · Synced Oct 21, 2026, 7:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study to Evaluate the Effects of the Speed Sleep Supplement on Sleep Quality and Quantity

NCT07564817
View directory record Official record
Conditions
Sleep Disturbance
Interventions
Dietary Supplement: Speed Sleep, Placebo
Dietary Supplement
Lead sponsor
Bio Nature Health
Industry
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 21, 2026, 7:35 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Sleep Quality in CHIMES (MF101)

NCT00454441
View directory record Official record
Conditions
Sleep Quality, Menopausal Symptoms
Interventions
MF101
Drug
Lead sponsor
Bionovo
Industry
Eligibility
40 Years to 60 Years · Female only
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
2
States / cities
San Francisco, California • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 30, 2007 · Synced Oct 21, 2026, 7:35 PM EDT
Completed Not applicable Interventional Results available

Effect of Theraworx/[pH]Uel on Night-time Leg Cramps and Spasm Symptoms

NCT03159260
View directory record Official record
Conditions
Leg Cramp, Nocturnal
Interventions
Theraworx, Placebo
Device · Other
Lead sponsor
Sport and Spine Rehab Clinical Research Foundation
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 25, 2019 · Synced Oct 21, 2026, 7:35 PM EDT
Completed Not applicable Interventional Results available

Efficacy of Sleep Interventions for Posttraumatic Stress Disorder (PTSD)

NCT00393874
View directory record Official record
Conditions
Anxiety Disorders, Mood Disorders, Insomnia, Nightmares
Interventions
Behavioral Sleep Intervention, Prazosin, Placebo
Behavioral · Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 55 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 24, 2016 · Synced Oct 21, 2026, 7:35 PM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Partial Sleep Restriction in Chronic Low Back Pain: A Feasibility Study

NCT07008924
View directory record Official record
Conditions
Chronic Low-back Pain, Insomnia, Sleep
Interventions
No intervention is provided. We monitor natural recovery to full sleep.
Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
25 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 6, 2025 · Synced Oct 21, 2026, 7:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Tai Chi Chuan on Psychobiological Indicators of Anxiety and Sleep Quality in Young Adults

NCT01624168
View directory record Official record
Conditions
Anxiety
Interventions
Anxiety Management Education, 10 week tai chi intervention, Enhanced tai chi instruction
Behavioral
Lead sponsor
Appalachian State University
Other
Eligibility
18 Years to 40 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Boone, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 8, 2016 · Synced Oct 21, 2026, 7:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Automating Peer Learning to Reduce Alcohol Use and Related Deviant Behavior in Secondary School

NCT04478240
View directory record Official record
Conditions
Substance Use, Stress, Relation, Interpersonal, Bullying, Victimisation, Mental Health Issue, Sleep, Inadequate, Social Skills
Interventions
PeerLearning.net
Behavioral
Lead sponsor
Oregon Research Behavioral Intervention Strategies, Inc.
Industry
Eligibility
Not listed
Enrollment
924 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 3, 2023 · Synced Oct 21, 2026, 7:35 PM EDT
Active, not recruiting Phase 2 Interventional

Nightmare Deconstruction and Reprocessing vs. NightWare Wristband

NCT06399874
View directory record Official record
Conditions
Nightmare
Interventions
Nightmare Deconstruction and Reprocessing, NightWare
Behavioral · Device
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
22 Years to 64 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 21, 2026, 7:35 PM EDT