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ClinicalTrials.gov public records Last synced Nov 13, 2026, 9:54 AM EST

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Showing 265–288 of 992 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Insomnia Disorders Clear all
Completed Phase 2 Interventional Results available

Xyrem(Sodium Oxybate) and Ambien(Zolpidem Tartrate) in the Treatment of Chronic Insomnia.

NCT00383643
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders
Interventions
zolpidem tartrate, sodium oxybate, Matching Placebos
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 1, 2017 · Synced Nov 13, 2026, 9:54 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility of Insomnia Tracking and Treatment in IBD

NCT04132024
View directory record Official record
Conditions
Inflammatory Bowel Diseases, Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I)
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
Not listed
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated May 11, 2021 · Synced Nov 13, 2026, 9:54 AM EST
Completed Phase 3 Interventional Results available

A Study to Evaluate Next-Dose Transition From Zolpidem to Lemborexant (LEM) for the Treatment of Insomnia

NCT04009577
View directory record Official record
Conditions
Insomnia
Interventions
LEM 5 mg, LEM 10 mg
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
17
States / cities
Glendale, Arizona • Sacramento, California • San Diego, California + 14 more
Source: ClinicalTrials.gov public record
Updated Apr 12, 2021 · Synced Nov 13, 2026, 9:54 AM EST
Active, not recruiting Not applicable Interventional

Safety and Effectiveness of the Luna System in People With Type 1 Diabetes Mellitus

NCT06627517
View directory record Official record
Conditions
Type 1 Diabetes Mellitus, Sleep Quality
Interventions
Episodic overnight patch pump
Device
Lead sponsor
Luna Diabetes
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
3
States / cities
Walnut Creek, California • Aurora, Colorado • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Nov 13, 2026, 9:54 AM EST
Enrolling by invitation No phase listed Observational

Adult Sleep Health in the Rural Appalachia and Mississippi Delta Region and Its Relationships With Cardiometabolic Health Disparities.

NCT06336525
View directory record Official record
Conditions
Sleep Apnea, Insomnia, Sleep Deprivation, Sleep Disorders, Circadian Rhythm, Sleepiness, Excessive Daytime, Fatigue
Interventions
Not listed
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
25 Years to 65 Years
Enrollment
3,680 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Nov 13, 2026, 9:54 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Management in Cancer Survivors

NCT00935376
View directory record Official record
Conditions
Insomnia
Interventions
Sleep Education Program, Mind-Body Bridging Program, Mindfulness Meditation Program
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 65 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Nov 13, 2026, 9:54 AM EST
Not listed Not applicable Interventional Accepts healthy volunteers

Non-Invasive At-Home Sleep Therapy System

NCT05970276
View directory record Official record
Conditions
Sleep, Sleep Duration, Sleep Quality
Interventions
Deep Sleep (N3) Enhancement with TES
Device
Lead sponsor
Brain Electrophysiology Laboratory Company
Industry
Eligibility
22 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 2, 2023 · Synced Nov 13, 2026, 9:54 AM EST
Completed Phase 3 Interventional Results available

Long-term Study of Lemborexant in Insomnia Disorder (SUNRISE 2)

NCT02952820
View directory record Official record
Conditions
Insomnia Disorder
Interventions
lemborexant, Placebo
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years and older
Enrollment
971 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
42
States / cities
Chandler, Arizona • Rogers, Arkansas • Beverly Hills, California + 35 more
Source: ClinicalTrials.gov public record
Updated Feb 6, 2020 · Synced Nov 13, 2026, 9:54 AM EST
Completed Not applicable Interventional

STATE Trial: SusTained Attention Training to Enhance Sleep

NCT02921074
View directory record Official record
Conditions
Insomnia
Interventions
Computerized Plasticity-Based Adaptive Cognitive Training, Commercially available computerized training
Other
Lead sponsor
Posit Science Corporation
Industry
Eligibility
55 Years to 80 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 11, 2018 · Synced Nov 13, 2026, 9:54 AM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Web-based Cognitive Behavioral Treatment for Insomnia in Dementia Caregivers

NCT04632628
View directory record Official record
Conditions
Insomnia Chronic, Dementia
Interventions
Web-based Cognitive Behavior Therapy for Insomnia (CBT-I)
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Nov 13, 2026, 9:54 AM EST
Not listed Not applicable Interventional

Sleep Treatment for Addiction Recovery

NCT04198311
View directory record Official record
Conditions
Insomnia, Alcohol Use Disorder, Substance Use Disorders
Interventions
CBT-I
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 10, 2022 · Synced Nov 13, 2026, 9:54 AM EST
Completed Not applicable Interventional Results available

A Trial of Group Psychotherapy for Veterans and Military Personnel With Post Traumatic Stress Disorder (PTSD)

NCT00984698
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Depression, Insomnia Disorder
Interventions
Cognitive Behavioral Social Rhythm Group Therapy, Present Centered Group Therapy
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
2
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 31, 2014 · Synced Nov 13, 2026, 9:54 AM EST
Completed Phase 2 Interventional

Cognitive Behavioral Therapy With or Without Armodafinil in Treating Cancer Survivors With Insomnia and Fatigue After Chemotherapy

NCT01019187
View directory record Official record
Conditions
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
Quality of Life Assessment, Questionnaire Administration, Placebo, Fatigue assessment and management, Sleep disorder therapy, Armodafinil, Management of Therapy, Cognitive Assessment, Management of therapy and complications, Fatifue assessment and management
Procedure · Other · Drug
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
21 Years to 75 Years
Enrollment
226 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 9, 2020 · Synced Nov 13, 2026, 9:54 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Helping Young Children Sleep

NCT01729715
View directory record Official record
Conditions
Insomnia
Interventions
Internet, DVD
Behavioral
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
6 Months to 36 Months
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 21, 2017 · Synced Nov 13, 2026, 9:54 AM EST
Completed Not applicable Interventional Results available

Trial on the Effect of Optically Modified Fiber Mattress Covers on Sleep Disturbances in Patients With Chronic Back Pain

NCT00969540
View directory record Official record
Conditions
Back Pain, Insomnia
Interventions
Active Mattress Cover, Placebo Mattress Cover
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Oct 27, 2026 · Synced Nov 13, 2026, 9:54 AM EST
Terminated Not applicable Interventional Accepts healthy volunteers

Integrative Cardiac Health Project Cognitive-Behavior Therapy for Insomnia

NCT02779023
View directory record Official record
Conditions
Insomnia, Cardiovascular Risk Factor
Interventions
Cognitive-Behavior Therapy for Insomnia (CBT-I)
Behavioral
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 11, 2018 · Synced Nov 13, 2026, 9:54 AM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

UCLA REST Study (REsearch on Sleep Techniques)

NCT05576090
View directory record Official record
Conditions
Sleep Disturbance, Inflammation, Psychosocial Functioning
Interventions
Mindfulness Meditation, Sleep Education
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 22 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Nov 13, 2026, 9:54 AM EST
Recruiting Early Phase 1 Interventional

CBTi for the Treatment of Insomnia in Type 1 Diabetes

NCT07091318
View directory record Official record
Conditions
Diabetes Mellitus Type 1, Insomnia
Interventions
Sleep quality improvement therapy, Healthy Living
Behavioral
Lead sponsor
University of Illinois Chicago
Other
Eligibility
18 Years to 65 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Nov 13, 2026, 9:54 AM EST
Completed Not applicable Interventional

Sleep Well: Digital Insomnia Treatment Program For Physicians

NCT05289596
View directory record Official record
Conditions
Sleep Disturbance, Insomnia, Stress, Psychological, Anxiety, Burnout, Professional
Interventions
Sleep Healthy Using the Internet (SHUT-i)
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 28, 2023 · Synced Nov 13, 2026, 9:54 AM EST
Completed Not applicable Interventional

Infant Night Wakings in Pediatric Primary Care

NCT02780596
View directory record Official record
Conditions
Insomnia, Night Wakings
Interventions
Item1, Item2, Item3, Item4, Item5
Other
Lead sponsor
Indiana University
Other
Eligibility
5 Months to 20 Months
Enrollment
3,501 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 22, 2018 · Synced Nov 13, 2026, 9:54 AM EST
Completed Phase 3 Interventional

Efficacy and Safety of M100907 on Sleep Maintenance Insomnia With a Sub-study in Stable Type II Diabetes Mellitus

NCT00495885
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders
Interventions
volinanserin (M100907), Placebo
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
848 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated May 26, 2016 · Synced Nov 13, 2026, 9:54 AM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers

NCT06737055
View directory record Official record
Conditions
Sleep, Postpartum Depression, Pregnancy Related, Insomnia, Sleep Deprivation, Sleep Hygiene, Sleep Disturbance
Interventions
Education about behavioral strategies to improve sleep
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
18 Years to 99 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 27, 2024 · Synced Nov 13, 2026, 9:54 AM EST
Not listed Not applicable Interventional

The Effects of MBSR on Patients With TBI and Chronic Insomnia

NCT03560843
View directory record Official record
Conditions
Chronic Insomnia, TBI (Traumatic Brain Injury)
Interventions
MBSR
Behavioral
Lead sponsor
Henry M. Jackson Foundation for the Advancement of Military Medicine
Other
Eligibility
18 Years to 60 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Nov 13, 2026, 9:54 AM EST
Recruiting Not applicable Interventional

Accelerated Treatment for Co-occurring Insomnia, Nightmares, and PTSD

NCT07069517
View directory record Official record
Conditions
Insomnia, PTSD - Post Traumatic Stress Disorder, Nightmares
Interventions
Cognitive-Behavioral Therapy for Insomnia (CBTi), Cognitive Behavioral Therapy for Nightmares (CBTn), Written Exposure Therapy (WET), Sleep Hygiene
Behavioral
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
18 Years to 65 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Kileen, Texas
Source: ClinicalTrials.gov public record
Updated Dec 3, 2025 · Synced Nov 13, 2026, 9:54 AM EST