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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Insomnia Disorders Clear all
Completed Phase 3 Interventional Results available

Long Term Safety Study of Study Drug (Eszopiclone) in Children and Adolescents With ADHD -Associated Insomnia

NCT00857220
View directory record Official record
Conditions
Insomnia, Attention Deficit Hyperactivity Disorder
Interventions
eszopiclone
Drug
Lead sponsor
Sumitomo Pharma America, Inc.
Industry
Eligibility
6 Years to 17 Years
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
89
States / cities
Tucson, Arizona • Little Rock, Arkansas • Carson, California + 70 more
Source: ClinicalTrials.gov public record
Updated Oct 25, 2017 · Synced Jun 25, 2026, 10:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Agewise Project 3: Brief Behavioral Treatment of Insomnia in Primary Care

NCT00177203
View directory record Official record
Conditions
Insomnia
Interventions
Brief Behavioral Treatment of Insomnia or Information
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
60 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2009
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 27, 2015 · Synced Jun 25, 2026, 10:07 PM EDT
Recruiting Not applicable Interventional

Effect of ANNE One-Wellue Device Array Use on Staff Bedside Vital Sign Measurement Activity

NCT06995742
View directory record Official record
Conditions
Vital Sign Evaluation, Vital Sign Monitoring, Sleep Quality, Provider Behavior, Patient Satisfaction
Interventions
Device Array Use, Routine Vital Sign Measurement
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Jun 25, 2026, 10:07 PM EDT
Completed Not applicable Interventional

Exploring the Outcomes and Financial Impact of a CBT-I Group Program Provided by Registered Nurses for Adults With Insomnia

NCT02038556
View directory record Official record
Conditions
Insomnia
Interventions
cognitive behaviorial therapy -Insomnia
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
2
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 7, 2015 · Synced Jun 25, 2026, 10:07 PM EDT
Completed Not applicable Interventional

Venlafaxine With or Without Zolpidem in Treating Hot Flashes and Associated Sleep Disorders in Women With Breast Cancer OR at High Risk for Developing Breast Cancer

NCT00084669
View directory record Official record
Conditions
Breast Cancer, Hot Flashes, Sleep Disorders
Interventions
venlafaxine, zolpidem tartrate, management of therapy complications
Drug · Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 27, 2010 · Synced Jun 25, 2026, 10:07 PM EDT
Enrolling by invitation Not applicable Interventional

Relieving Pain and Improving Sleep: Evaluating Topical Pain Relief and Sleep Patches

NCT06505005
View directory record Official record
Conditions
Pain, Back, Pain, Acute, Sleep Disorder, Sleep Disorders, Circadian Rhythm, Sleep, Sleep Deprivation, Insomnia
Interventions
Drug- free, non-invasive patch (FREEDOM or REM Patch) with haptic vibrotactile trigger technology (VTT) Other Names:, Sham Patch without haptic vibrotactile trigger technology (VTT)
Device
Lead sponsor
SuperPatch Limited LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Tyrone, Georgia
Source: ClinicalTrials.gov public record
Updated Dec 7, 2025 · Synced Jun 25, 2026, 10:07 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Assess the Pharmacodynamic Effects of SAGE-217 in Healthy Adults Using an Insomnia Model

NCT03284931
View directory record Official record
Conditions
Healthy
Interventions
SAGE-217 high dose, Placebo, SAGE-217 low dose
Drug
Lead sponsor
Biogen
Industry
Eligibility
18 Years to 64 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 28, 2023 · Synced Jun 25, 2026, 10:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Impact of Behavioral Treatment of Insomnia on Nighttime Urine Production

NCT03883724
View directory record Official record
Conditions
Sleep Fragmentation, Poor Quality Sleep, Nocturia, Nocturnal Enuresis
Interventions
Brief behavioral treatment of insomnia (BBTI), Information-only control (IC)
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
65 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 21, 2022 · Synced Jun 25, 2026, 10:07 PM EDT
Completed Not applicable Interventional Results available

Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)

NCT02697435
View directory record Official record
Conditions
Chronic Low Back Pain, Hip Ostearthritis, Myofascial Pain Syndrome, Fibromyalgia, Depression, Maladaptive Coping, Lumbar Spinal Stenosis, Insomnia, Sacroiliac Joint Pain, Lateral Hip and Thigh Pain, Anxiety, Dementia, Recent Leg Length Discrepancy
Interventions
Patient-Centered Care, Imaging-Directed Care
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years to 89 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Pittsburgh, Pennsylvania • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 18, 2019 · Synced Jun 25, 2026, 10:07 PM EDT
Completed Not applicable Interventional

Feasibility of Web-based CBT-I Intervention in Individuals With Multiple Sclerosis

NCT03783585
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Cognitive behavioral therapy for insomnia, Cognitive behavioral therapy for insomnia + biweekly support
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Jun 25, 2026, 10:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep in Osteoarthritis Project

NCT00592449
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders, Osteoarthritis
Interventions
Cognitive behavioral therapy (CBT) for insomnia, Behavioral desensitization treatment for insomnia
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
35 Years to 100 Years
Enrollment
209 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 22, 2019 · Synced Jun 25, 2026, 10:07 PM EDT
Completed Not applicable Interventional

Development of an Insomnia Treatment for Depressed Adolescents

NCT02163564
View directory record Official record
Conditions
Insomnia, Depression
Interventions
Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
13 Years to 19 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 28, 2016 · Synced Jun 25, 2026, 10:07 PM EDT
Completed Phase 4 Interventional Results available

A Pilot Study of Suvorexant for Insomnia in Parkinson Disease

NCT02729714
View directory record Official record
Conditions
Insomnia
Interventions
Suvorexant, Placebo
Drug
Lead sponsor
Burdick, Daniel, M.D.
Individual
Eligibility
30 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Kirkland, Washington
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Jun 25, 2026, 10:07 PM EDT
Not listed Not applicable Interventional

Safety and Efficacy of an Ambulatory Biofeedback Device for Primary Insomnia

NCT00415714
View directory record Official record
Conditions
Primary Insomnia
Interventions
Portable Biofeedback
Device
Lead sponsor
Helicor
Industry
Eligibility
18 Years to 55 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 28, 2007 · Synced Jun 25, 2026, 10:07 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Physician Mental Health Study for Medical Trainees

NCT02950363
View directory record Official record
Conditions
Mental Illness, Burnout Syndrome
Interventions
Not listed
Lead sponsor
Scripps Translational Science Institute
Other
Eligibility
19 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 27, 2017 · Synced Jun 25, 2026, 10:07 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Sleep Hygiene Intervention to Improve Sleep Health in Urban, Latino Middle School Children

NCT06942455
View directory record Official record
Conditions
Sleep, Sleep Quality, Intervention Study, Ethnic Minority
Interventions
SIESTA, Sleep education and health education control
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
11 Years to 13 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Jun 25, 2026, 10:07 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Pistachio Snacking and Metabolic Flexibility

NCT07340125
View directory record Official record
Conditions
Overweight (BMI > 25), Obese But Otherwise Healthy Participants, Overweight or Obese, Obese Patients (BMI ≥ 30 kg/m²), Poor Sleep Quality, Healthy Participants, Physically Inactive
Interventions
Pistachio
Other
Lead sponsor
University of South Carolina
Other
Eligibility
25 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Jun 25, 2026, 10:07 PM EDT
Completed Phase 3 Interventional Results available

Study to Assess the Efficacy and Safety of ACT-541468 (Daridorexant) in Adult and Elderly Subjects With Insomnia Disorder

NCT03545191
View directory record Official record
Conditions
Insomnia Disorder
Interventions
Daridorexant 25 mg, Daridorexant 50 mg, Placebo
Drug · Other
Lead sponsor
Idorsia Pharmaceuticals Ltd.
Industry
Eligibility
18 Years and older
Enrollment
930 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
36
States / cities
Anniston, Alabama • Birmingham, Alabama • Little Rock, Arkansas + 33 more
Source: ClinicalTrials.gov public record
Updated Mar 24, 2022 · Synced Jun 25, 2026, 10:07 PM EDT
Completed Not applicable Interventional

Identifying At-Risk Patients and Predicting Deterioration of In-Patients Using Continuous Heart Rate, Respiratory Rate, and Movement Monitoring

NCT03010774
View directory record Official record
Conditions
Sleep Quality
Interventions
Risk Stratification, Usual Care
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
166 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 26, 2020 · Synced Jun 25, 2026, 10:07 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Non-Invasive At-Home Sleep Therapy System

NCT05970276
View directory record Official record
Conditions
Sleep, Sleep Duration, Sleep Quality
Interventions
Deep Sleep (N3) Enhancement with TES
Device
Lead sponsor
Brain Electrophysiology Laboratory Company
Industry
Eligibility
22 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Jun 25, 2026, 10:07 PM EDT
Completed Not applicable Interventional Results available

PracticeGround: Transforming Training and Delivery of Mental Health EBPs

NCT02314624
View directory record Official record
Conditions
Depression, Insomnia, Suicide
Interventions
Behavioral Activation for Depression, Cognitive Behavior Therapy for Insomnia, Collaborative Assessment and Management of Suicidality, Care-as-Usual Psychotherapy
Behavioral
Lead sponsor
Evidence-Based Practice Institute, Seattle, WA
Industry
Eligibility
18 Years and older
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Jun 25, 2026, 10:07 PM EDT
Not listed Phase 3 Interventional

Effect of Rozerem on the Perception of GERD Symptoms in Patients With Chronic Insomnia.

NCT01128582
View directory record Official record
Conditions
Gastroesophageal Reflux Disease, Chronic Insomnia
Interventions
Rozerem (ramelteon), placebo
Drug
Lead sponsor
Southern Arizona VA Health Care System
Federal
Eligibility
Up to 82 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 11, 2011 · Synced Jun 25, 2026, 10:07 PM EDT
Completed Not applicable Interventional Results available

Trial on the Effect of Optically Modified Fiber Mattress Covers on Sleep Disturbances in Patients With Chronic Back Pain

NCT00969540
View directory record Official record
Conditions
Back Pain, Insomnia
Interventions
Active Mattress Cover, Placebo Mattress Cover
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Dec 2, 2014 · Synced Jun 25, 2026, 10:07 PM EDT
Terminated Not applicable Interventional Results available

Respiratory Resistance Training on Sleep Quality in Persons With Spinal Cord Injury

NCT00629850
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Powerlung Performer
Device
Lead sponsor
Texas State University, San Marcos
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
San Marcos, Texas
Source: ClinicalTrials.gov public record
Updated May 7, 2019 · Synced Jun 25, 2026, 10:07 PM EDT