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ClinicalTrials.gov public records Last synced Nov 9, 2026, 6:20 AM EST

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Showing 25–48 of 990 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Insomnia Disorders Clear all
Completed Phase 2 Interventional Accepts healthy volunteers

A Randomized, Double Blind, Parallel Group, Placebo Controlled, Multicenter Outpatient Trial Of PD 0200390 In Adults With Primary Insomnia

NCT00569972
View directory record Official record
Conditions
Insomnia
Interventions
PD 0200390, Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 64 Years
Enrollment
682 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
71
States / cities
Birmingham, Alabama • Phoenix, Arizona • Scottsdale, Arizona + 57 more
Source: ClinicalTrials.gov public record
Updated Jul 25, 2012 · Synced Nov 9, 2026, 6:20 AM EST
Active, not recruiting Not applicable Interventional

Digital CBT for Insomnia and Depression

NCT05456607
View directory record Official record
Conditions
Depression, Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia, Cognitive Behavioral Therapy for Depression, Mood Monitoring
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
1,175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Nov 9, 2026, 6:20 AM EST
Completed Phase 3 Interventional

A Study of Eszopiclone in Subjects With Insomnia Related to Major Depressive Disorder

NCT00368030
View directory record Official record
Conditions
Insomnia, Depressive Disorder, Major
Interventions
Eszopiclone, Placebo
Drug · Other
Lead sponsor
Sumitomo Pharma America, Inc.
Industry
Eligibility
21 Years to 64 Years
Enrollment
545 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004
U.S. locations
65
States / cities
Birmingham, Alabama • Peoria, Arizona • Tucson, Arizona + 62 more
Source: ClinicalTrials.gov public record
Updated Feb 22, 2012 · Synced Nov 9, 2026, 6:20 AM EST
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Improving Sleep With a Digital Cognitive Behavioral Therapy for Insomnia Application

NCT05991492
View directory record Official record
Conditions
Insomnia
Interventions
Web-based Cognitive Behavioral Therapy for Insomnia (wCBT-I
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Nov 9, 2026, 6:20 AM EST
Terminated Not applicable Interventional

Solving Insomnia Electronically: Sleep Treatment for Asthma

NCT03327519
View directory record Official record
Conditions
Asthma, Insomnia
Interventions
SHUTi, Emmi
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 75 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 21, 2023 · Synced Nov 9, 2026, 6:20 AM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

DESCANSO, a Mental Health Intervention for Depression, Insomnia, and Fatigue Symptoms in Latino People With Cancer

NCT07225088
View directory record Official record
Conditions
Solid Tumor, Solid Tumor, Adult
Interventions
DESCANSO/Depresión/Depressed Mood, Cansancio/Fatigue, and Sueño/Sleep; Rest in English
Behavioral
Lead sponsor
Ponce Medical School Foundation, Inc.
Industry
Eligibility
21 Years to 100 Years
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 23, 2026 · Synced Nov 9, 2026, 6:20 AM EST
Completed Phase 2Phase 3 Interventional Results available

Mindfulness Versus Pharmacotherapy for Chronic Insomnia: A Pilot Study

NCT00515177
View directory record Official record
Conditions
Chronic Insomnia, Primary Insomnia
Interventions
Mindfulness-Based Stress Reduction, eszopiclone
Behavioral · Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
2
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 29, 2013 · Synced Nov 9, 2026, 6:20 AM EST
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Magnesium Supplement for Sleep Quality in Women With Poor Sleep

NCT07708857
View directory record Official record
Conditions
Sleep Quality
Interventions
Magnesium Breakthrough, Placebo
Dietary Supplement
Lead sponsor
Jacksonville University
Other
Eligibility
35 Years to 60 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Nov 9, 2026, 6:20 AM EST
Completed Not applicable Interventional

Treating Insomnia & Nightmares After Trauma: Impact on Symptoms & Quality of Life

NCT01009112
View directory record Official record
Conditions
Nightmares, Insomnia, Posttraumatic Stress Disorder
Interventions
PTSD + IRT/CBT-I, PTSD + Supportive Care Therapy
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 28, 2015 · Synced Nov 9, 2026, 6:20 AM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Implementing and Evaluating Computer-Based Interventions for Mental Health: Testing an Implementation Strategy for VA Outpatient Care

NCT03151083
View directory record Official record
Conditions
Insomnia
Interventions
Internet-based Self-help Insomnia Intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 21, 2023 · Synced Nov 9, 2026, 6:20 AM EST
Recruiting Not applicable Interventional

Treating Insomnia in Mild Cognitive Impairment

NCT06687161
View directory record Official record
Conditions
Mild Cognitive Impairment (MCI), Insomnia, Subjective Cognitive Decline (SCD)
Interventions
Transcranial Magnetic Stimulation (TMS) therapy, Cognitive behavioral therapy for insomnia (CBT-I)
Device · Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
60 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 5, 2026 · Synced Nov 9, 2026, 6:20 AM EST
Completed Not applicable Interventional Results available

Sleep Without Insomnia or The Use of Chronic Hypnotics

NCT03687086
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders
Interventions
Program A, Program B
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
55 Years and older
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Nov 9, 2026, 6:20 AM EST
Active, not recruiting Not applicable Interventional

Sleep for Health Study on the Effects of Cognitive Behavioral Therapy for Insomnia on Diabetes Risk

NCT06067139
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Prediabetic State, Sleep Initiation and Maintenance Disorders
Interventions
SHUTi, Patient Education
Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
22 Years to 79 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Nov 9, 2026, 6:20 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow

NCT00634608
View directory record Official record
Conditions
Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy, Bursitis, Depression, Anxiety, Diabetes Mellitus, Esophageal Reflux, HIV Infections, Hyperlipidemia, Hypertension, Insomnia, Irritable Bowel Syndrome, Obesity, Osteoporosis (Senile), Shoulder Pain, Sinusitis, Symptomatic Menopause, Urinary Incontinence, Urinary Tract Infection, Vaginitis
Interventions
Health Information Prescription
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 30, 2016 · Synced Nov 9, 2026, 6:20 AM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

UCLA REST Study (REsearch on Sleep Techniques)

NCT05576090
View directory record Official record
Conditions
Sleep Disturbance, Inflammation, Psychosocial Functioning
Interventions
Mindfulness Meditation, Sleep Education
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 22 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Nov 9, 2026, 6:20 AM EST
Completed Not applicable Interventional Results available

The Efficacy of CBT-I in Alcoholics & Its Effects on Remission & Relapse

NCT01987089
View directory record Official record
Conditions
Insomnia
Interventions
Cognitive Behavioral Therapy for Insomnia (CBT-I)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
21 Years to 70 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 7, 2020 · Synced Nov 9, 2026, 6:20 AM EST
Completed Early Phase 1 Interventional

Bio Electro Stimulation Therapy for Parkinson's Disease

NCT03014050
View directory record Official record
Conditions
Parkinson Disease
Interventions
e-Tapper TT-R1
Device
Lead sponsor
Boston University
Other
Eligibility
50 Years to 75 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 3, 2020 · Synced Nov 9, 2026, 6:20 AM EST
Completed Not applicable Interventional

Mindfulness Meditation and Insomnia in Alzheimer Disease Caregivers

NCT03538574
View directory record Official record
Conditions
Insomnia Chronic
Interventions
CBT-I, MAP-I
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
45 Years to 95 Years
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 4, 2022 · Synced Nov 9, 2026, 6:20 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

A Clinical Trial to Evaluate the Effects of a Topical Roll-on and Diffuser Blend on Sleep Quality and Sleep Duration

NCT07779382
View directory record Official record
Conditions
Sleep Quality, Sleep Duration, Fatigue, Energy Levels, Overall Health and Well-Being
Interventions
Sleep Well Diffuser Blend followed by Sleep Well Roll-On
Dietary Supplement
Lead sponsor
Saie Beauty
Industry
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Nov 9, 2026, 6:20 AM EST
Completed Not applicable Interventional

The Effect of Cognitive Behavioral Therapy for Insomnia on Type 2 Diabetes Health Outcomes

NCT03713996
View directory record Official record
Conditions
Type2 Diabetes, Insomnia
Interventions
Cognitive behavioral therapy for insomnia, Health Education
Behavioral · Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
40 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Nov 9, 2026, 6:20 AM EST
Completed Not applicable Interventional Results available

Transcranial Magnetic Stimulation for Treatment of Insomnia

NCT02196025
View directory record Official record
Conditions
Insomnia
Interventions
Transcranial magnetic stimulation
Device
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 65 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Nov 9, 2026, 6:20 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Mechanisms Underlying the Sleep Promoting Effect of Cherry Juice Standardized to Its Proanthocyanidin Content

NCT01669317
View directory record Official record
Conditions
Insomnia, Sleep Problem
Interventions
8-ounce glass of cherry juice, Artificial Cherry Juice
Other
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
65 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 18, 2015 · Synced Nov 9, 2026, 6:20 AM EST
Completed Not applicable Interventional Results available

The SleepWell Study - Chronotherapeutic Intervention to Improve Sleep Following ACS

NCT05299723
View directory record Official record
Conditions
Sleep Disturbance, Insomnia, Acute Coronary Syndrome
Interventions
BLT Intervention, BLB Intervention, Sleep Hygiene Education
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Nov 9, 2026, 6:20 AM EST
Completed Not applicable Interventional

Cognitive-Behavioral Therapy for Chronic Insomnia After Breast Cancer Treatment

NCT00672217
View directory record Official record
Conditions
Breast Cancer
Interventions
Cognitive Behavioral Therapy for Insomnia (CBTI), Behavioral Placebo Treatment
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 65 Years · Female only
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 27, 2015 · Synced Nov 9, 2026, 6:20 AM EST