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ClinicalTrials.gov public records Last synced Nov 14, 2026, 5:54 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 649–672 of 992 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Insomnia Disorders Clear all

Conditions: Primary Insomnia
Interventions: Eplivanserin, Placebo; Drug
Lead sponsor: Sanofi; Industry
Eligibility: 18 Years and older
Enrollment: 637 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Bridgewater, New Jersey

Conditions: Anxiety Disorder, Worry, Uncertainty, Sleep Disorders, Insomnia, Fatigue, Pain, Depression, Cognitive-behavioral Therapy, Psychological Intervention, Esophageal Cancer, Pancreatic Cancer, Leukemia, Lung Cancer, Multiple Myeloma, Ovarian Neoplasm, Stage III or IV Cervical or Uterine Cancer, Stage IIIB, IIIC, or IV Breast Cancer, Glioblastoma Multiforme, Relapsed Lymphoma, Stage III or IV Colorectal Cancer, Stage IIIC or IV Melanoma
Interventions: Cognitive-behavioral therapy for worry, uncertainty & insomnia; Behavioral
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Insomnia, Sleep Health, Cardiometabolic Health
Interventions: Mindfulness-based therapy for insomnia (MBTI); Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 70 Years · Female only
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 2
States / cities: New Haven, Connecticut • West Haven, Connecticut

Conditions: Neurobehavioral Manifestations, Sleep Deprivation, Dyssomnias
Interventions: Sleep promoting interventions; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 88 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Fibromyalgia, Insomnia
Interventions: Eszopiclone, placebo; Drug
Lead sponsor: Lesley A. Allen, Ph.D.; Other
Eligibility: 18 Years to 64 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Piscataway, New Jersey

Conditions: Shift-Work Sleep Disorder, Insomnia, Restless Leg Syndrome, Obstructive Sleep Apnea, Impaired Driving
Interventions: Sleep health education provided via a web-based program, Sleep disorder detection and treatment, Optimization of Sleep in Fire Station; Behavioral · Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 620 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Insomnia, Primary, Major Depressive Disorder, Rumination
Interventions: digital Cognitive Behavioral Therapy for Insomnia, face-to-face Cognitive Behavioral Therapy for Insomnia, Sleep Hygiene Education Control; Behavioral
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years and older
Enrollment: 1,237 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: Novi, Michigan

Conditions: Chronic Insomnia
Interventions: Brief Behavioral Treatment for Insomnia; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Nightmare
Interventions: Nightmare Deconstruction and Reprocessing; Behavioral
Lead sponsor: Uniformed Services University of the Health Sciences; Federal
Eligibility: 18 Years to 64 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 2
States / cities: San Diego, California • Bethesda, Maryland

Conditions: Poor Quality Sleep
Interventions: Refrain from caffeine techniques, Project REST Platform; Behavioral
Lead sponsor: University of Arizona; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Tucson, Arizona

Conditions: Insomnia, Malignant Solid Neoplasm
Interventions: Biospecimen Collection, Placebo Administration, Single Agent Therapy; Procedure · Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 25 Years and older
Enrollment: 69 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Transient Insomnia
Interventions: SM-1, Active Comparator; Drug
Lead sponsor: Sequential Medicine Ltd; Industry
Eligibility: 25 Years to 55 Years
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Severe Sleep Apnea, Severe Insomnia, Epileptiform Activity
Interventions: Polysomnography Data, Jawbone UP®, Fitbit Charge ®; Device
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: New York, New York

Conditions: Anxiety, Depression - Major Depressive Disorder, Burnout, Insomnia, Resilience, Feasibility, Acceptability
Interventions: Transcendental Meditation; Behavioral
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Opioid Use Disorder, Opioid Use, Insomnia, Orexin Antagonist
Interventions: Placebo, Lemborexant 10 MG; Drug
Lead sponsor: Virginia Commonwealth University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Richmond, Virginia

Conditions: Insomnia
Interventions: Not listed
Lead sponsor: Power Life Sciences Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Asthma, Insomnia
Interventions: SHUTi, Emmi; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 75 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Cerebrovascular Accident, Sleep Disorder
Interventions: CES; Device
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Transient Insomnia
Interventions: SM-1, D+Z, D+L, Placebo; Drug
Lead sponsor: Sequential Medicine Ltd; Industry
Eligibility: 18 Years and older
Enrollment: 85 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 2
States / cities: Atlanta, Georgia • New York, New York

Conditions: Depression - Major Depressive Disorder, Insomnia
Interventions: Alpha phase-locked auditory stimulation, Sham Stimulation; Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 20 Years to 50 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Insomnia
Interventions: Sleep Healthy Using the Internet (SHUTi), Patient education; Behavioral
Lead sponsor: Georgetown University; Other
Eligibility: 21 Years and older · Male only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Insomnia, Postoperative Delirium, Delayed Neurocognitive Recovery, Postoperative Neurocognitive Disorder
Interventions: digital Cognitive Behavioral Therapy for Insomnia (dCBT-I), Sleep Health Education; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 65 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Anxiety, Stress
Interventions: Alcohol Alternative Herbal Tincture (Test Product), Placebo; Dietary Supplement
Lead sponsor: Apothekary; Industry
Eligibility: 21 Years to 65 Years
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Santa Monica, California

Conditions: Sleep Architecture, Mild Traumatic Brain Injury, Sleep, Sleep and Circadian Problems
Interventions: Cognitive behavioral Therapy for insomnia (CBT-I); Behavioral
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years to 60 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Columbia, Missouri

Search by objective public record fields.

Efficacy and Safety of Eplivanserin 5mg/Day in Insomnia Characterized by Sleep Maintenance Difficulties

Cognitive-Behavioral Intervention for Worry, Uncertainty, and Insomnia for Cancer Survivors

Project Women's Insomnia Sleep Health Equity Study (WISHES)

Intensive Care Unit (ICU) Sleep Quality and Neurocognitive Performance

Eszopiclone in the Treatment of Insomnia and Fibromyalgia

Fire Fighter Fatigue Management Program: Operation Fight Fatigue

Sleep To Reduce Incident Depression Effectively

Brief Behavioral Treatment of Insomnia in Military Veterans: Phase 1

Nightmare Deconstruction and Reprocessing Pilot

Project REST: Club Sports

THC Versus THC/CBD Versus Placebo to Improve Sleep Quality for Patients With Solid Organ Cancer and Insomnia

SM-1 vs. an Active Comparator in A Model of Transient Insomnia

Mainstream Sleep Tracking Devices vs Polysomnography

Transcendental Meditation Intervention to Reduce Burnout and Enhance Resilience Among NewYork-Presbyterian Hospital and Weill Cornell Medicine Employees and Residents

Effects of Lemborexant on Insomnia and Its Relationship to Mood and Behavior on Opioid Use Disorder Subjects

Appraising Clinical Trial Experiences of Patients With Insomnia

Solving Insomnia Electronically: Sleep Treatment for Asthma

Cranial Electrical Stimulation (CES) as Treatment for Insomnia in Patients With Subacute Stroke

SM-1 vs 2 Comparators and Placebo in Participants With a History of Transient Insomnia.

Auditory Stimulation for Insomnia and Depression

Assessing the Feasibility of Web-based Insomnia Treatment Among Prostate Cancer Survivors

Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients

A Clinical Trial to Assess the Impact of an Alcohol Alternative Herbal Tincture on Signs of Stress Anxiety and Sleep Quality.

Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI)