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ClinicalTrials.gov public records Last synced Nov 12, 2026, 6:21 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 145–168 of 992 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Insomnia Disorders Clear all

Conditions: Insomnia, Insomnia Due to Medical Condition, Cancer
Interventions: STEP-YA with Coaching, STEP-YA without Coaching; Behavioral
Lead sponsor: Dana-Farber Cancer Institute; Other
Eligibility: 20 Years to 39 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Insomnia, Primary
Interventions: LFMS - Active, LFMS - Sham; Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 65 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Insomnia Chronic
Interventions: PEAR-003b PDT Intervention, Fitbit, Sleep education materials; Device · Behavioral
Lead sponsor: Yale University; Other
Eligibility: 22 Years to 64 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 2
States / cities: New Haven, Connecticut • Rochester, Minnesota

Conditions: Sleep, Diet Modification
Interventions: Diet Quality; Other
Lead sponsor: University of Chicago; Other
Eligibility: 21 Years to 40 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Sleep Disturbance
Interventions: melatonin; Dietary Supplement
Lead sponsor: Rothman Institute Orthopaedics; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Egg Harbor, New Jersey

Conditions: Insomnia, Depression
Interventions: Cognitive Behavioral Therapy for Insomnia (CBTI), Perinatal Understanding of Mindful Awareness for Sleep (PUMAS); Behavioral
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Novi, Michigan

Conditions: Insomnia
Interventions: Cognitive Behavioral Therapy for Insomnia (CBT-I); Behavioral
Lead sponsor: Corporal Michael J. Crescenz VA Medical Center; Federal
Eligibility: 18 Years to 65 Years · Male only
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Depression, Anxiety, Insomnia
Interventions: Eszopiclone, Placebo; Drug
Lead sponsor: Steward St. Elizabeth's Medical Center of Boston, Inc.; Other
Eligibility: 18 Years to 55 Years · Female only
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Chronic Insomnia
Interventions: CBTI, BBTI; Behavioral
Lead sponsor: VA Pittsburgh Healthcare System; Federal
Eligibility: 18 Years and older
Enrollment: 92 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Insomnia, Depression
Interventions: Cognitive Behavioral Therapy for Insomnia; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 13 Years to 19 Years
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Myofascial Pain, Myalgia
Interventions: Brief Behavioral Therapy for Insomnia, BBTI, Physical Self-Regulation, PSR; Behavioral
Lead sponsor: Ian Boggero, PhD; Other
Eligibility: 18 Years and older
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: Insomnia
Interventions: Tele-Brief Behavioral Treatment for Insomnia, Tele-Cognitive-Behavioral Therapy for Insomnia; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 350 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Migraine Headache, Sleep, Photophobia
Interventions: Ambient Lighting Condition; Other
Lead sponsor: Arizona State University; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Tempe, Arizona

Conditions: Insomnia, Chronic Pain
Interventions: Cognitive Behavioral Therapy for Insomnia (CBT-I), Interdisciplinary Pain Rehabilitation Program (IPRP); Behavioral
Lead sponsor: Mary Free Bed Rehabilitation Hospital; Other
Eligibility: 18 Years and older
Enrollment: 114 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Grand Rapids, Michigan

Conditions: TBI (Traumatic Brain Injury)
Interventions: InFuSE, Patient Education/Group Discussion; Behavioral
Lead sponsor: Washington D.C. Veterans Affairs Medical Center; Federal
Eligibility: 18 Years to 65 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Sleep, Sleep Quality, Sleepiness, Daytime, Technology
Interventions: Accurate Sleep Data Feedback, Inflated Sleep Data Feedback, Deflated Sleep Data Feedback, Accurate Sleep Data Feedback + Sleep-related Educational Information; Behavioral
Lead sponsor: NextSense, Inc.; Industry
Eligibility: 25 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Depression, Insomnia
Interventions: CBT-I (Cognitive Behavioral Therapy for Insomnia) with rTMS, Repetitive Transcranial Magnetic Stimulation; Behavioral · Device
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 18 Years to 85 Years
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Alzheimer Disease, Dementia, Sleep Disturbance
Interventions: Non-Contact Sleep Quality Monitor System; Device
Lead sponsor: Indiana University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Tourette's Disorder, Insomnia
Interventions: Forehead Temperature-Regulating Therapy; Device
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years to 50 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Fibromyalgia, Insomnia, Chronic Widespread Pain
Interventions: Cognitive Behavioral Treatment-Insomnia, Sleep Hygiene Education; Behavioral
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years and older · Female only
Enrollment: 131 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2025
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Alzheimer Disease, Dementia, Sleep Disorder, Sleep Disturbance
Interventions: LOCK Sleep Program, No intervention (control period/baseline data collection); Behavioral · Other
Lead sponsor: University of Alabama, Tuscaloosa; Other
Eligibility: 50 Years and older
Enrollment: 456 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 3
States / cities: Lakewood, Colorado • Murfreesboro, Tennessee • San Marcos, Texas

Conditions: Advanced Cancer, Anorexia, Weight Loss, Insomnia
Interventions: Mirtazapine, Placebo; Drug
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 98 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2027
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Orthopedic Trauma, Sleep Quality
Interventions: Standard Postoperative Care, Zolpidem, Melatonin, Sleep Hygiene Education, Actigraph GT3X-BT Actigraph; Other · Drug · Dietary Supplement + 2 more
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Trauma, Insomnia, Nightmares
Interventions: Cognitive Processing Therapy-Cognitive Only (CPT), Cognitive Behavioral Therapy of Insomnia and Nightmares (CBTin), Continuation Cognitive Processing Therapy-Cognitive Only (CPT); Behavioral
Lead sponsor: University of North Texas, Denton, TX; Other
Eligibility: 18 Years to 50 Years
Enrollment: 94 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Fort Hood, Texas

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Sleep Treatment Education Program for Young Adult Cancer Survivors (STEP-YA)

Study of Low Field Magnetic Stimulation (LFMS) on Measures of Sleep

Prescription Digital Therapeutic for the Treatment of Insomnia

Diet and Sleep Monitoring

Sleep Quality and Pain Medication Use Following Arthroscopic Rotator Cuff Repair

Improving Negative Stressful Perseverations in Insomnia to Revitalize Expecting Moms (INSPIRE)

The Effect of Family History on Insomnia During Sobriety in Alcoholics

The Effects of Eszopiclone and Lexapro on Prefrontal Glutamate and GABA in Depression With Anxiety and Insomnia

Implementation of Brief Insomnia Treatments - Clinical Trial

Development of an Insomnia Treatment for Depressed Adolescents

BBTI vs PSR in Musculoskeletal Orofacial Pain Adults

A Hybrid Effectiveness Implementation Trial Evaluating Behavioral Treatments for Insomnia for Socioeconomically Disadvantaged Adults in Primary Care

Light Exposure, Migraine Outcomes, and Sleep Quality

Dual Treatment of Chronic Pain and Insomnia

Effects of an Interdisciplinary Fitness and Social Engagement Intervention

Nextsense Brain-sensing Buds Study

Cognitive Behavioral Therapy for Insomnia with RTMS

Automated, Assistive, Non-Contact Sleep Quality Monitor for Individuals With Alzheimer's Disease

Forehead Temperature-Regulating Therapy for Insomnia in Adults With Tourette's Disorder

Sleep and Pain Interventions in Women With Fibromyalgia

Enhancing Sleep Quality for Nursing Home Residents With Dementia - R33 Phase

Effects of Mirtazapine on Appetite in Advanced Cancer Patients

Sleep Quality and the Efficacy of a Multimodal Sleep Pathway in Hospitalized Orthopedic Trauma Patients

Treatment of Comorbid Sleep Disorders and Post Traumatic Stress Disorder (PTSD)