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Conditions: Systolic Blood Pressure, Blood Pressure, Depression - Major Depressive Disorder, Anxiety, Sleep Quality, Physical Function, Cognitive Function
Interventions: Inspiratory Muscle Strength Training High-Resistance, Inspiratory Muscle Strength Training Low-Resistance; Device
Lead sponsor: Florida State University; Other
Eligibility: 60 Years to 80 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Inspiratory Muscle Training, Blood Pressure
Interventions: O2 Trainer, Deep breathing; Other
Lead sponsor: Sam Houston State University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 8 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 1
States / cities: Conroe, Texas

Conditions: Asthma
Interventions: Inspiratory muscle training (IMT), Exercise alone, IMT and Exercise; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 10 Years to 17 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Multiple Sclerosis
Interventions: Inspiratory Muscle Trainer (IMT); Other
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 2
States / cities: Boston, Massachusetts • Flint, Michigan

Conditions: Obesity
Interventions: High-resistance inspiratory muscle strength training, Very-low-resistance inspiratory muscle strength training; Device
Lead sponsor: Florida State University; Other
Eligibility: 18 Years to 45 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Respiratory Muscle Training
Interventions: POWERbreathe Plus IMT; Device
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 6 Years to 12 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Diabetes Mellitus Type 2
Interventions: Inspiratory Muscle Strength Training (IMST), Sham Training; Device
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: 14 Years to 40 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Seattle, Washington

Conditions: Lung Transplantation, Chronic Lung Disease, Muscle Weakness, Rehabilitation
Interventions: IMT- Intervention group, IMT- Placebo group; Device
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Systolic Hypertension, Brachial Artery Flow-mediated Dilation
Interventions: POWERbreathe K5; Device
Lead sponsor: University of Minnesota; Other
Eligibility: 18 Years and older
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Heart Failure With Reduced Ejection Fraction
Interventions: Powerbreathe; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Healthy, Heart Failure
Interventions: Inspiratory muscle training; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Failure to Wean, Respiratory Failure, Ventilator Dependent
Interventions: inspiratory muscle strength training; Procedure
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: 16 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2009
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Menopause, Hot Flashes, Blood Pressure Regulation
Interventions: High-Resistance Inspiratory Muscle Strength Training, Low-Resistance Inspiratory Muscle Strength Training, POWERbreathe K3 device; Behavioral · Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 45 Years to 60 Years · Female only
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Hypertension, Prehypertension, Aging
Interventions: Inspiratory muscle strength training, Sham training; Other
Lead sponsor: Douglas Seals; Other
Eligibility: 50 Years to 64 Years
Enrollment: 64 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Boulder, Colorado

Conditions: Post-Lung Transplantation Bronchiectasis
Interventions: POWERBreathe Plus®, Cardiopulmonary rehabilitation post lung transplant; Device · Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Early Stage Breast Carcinoma, Dyspnea
Interventions: Inspiratory muscle training; Behavioral
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Critically Ill, Respiratory Failure
Interventions: Inspiratory Muscle Trainer; Device
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 90 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Constipation, Constipation by Outlet Obstruction, Constipation-predominant Irritable Bowel Syndrome, Constipation - Functional
Interventions: Standard Physical Therapy Care, Aerobic and Inspiratory Muscle Training; Other
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Coral Gables, Florida

Conditions: Frailty, Ventral Hernia
Interventions: Prehabilitation, Standard of Care (SOC); Behavioral · Other
Lead sponsor: Prisma Health-Upstate; Other
Eligibility: 65 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Greenville, South Carolina

Conditions: Chronic Kidney Diseases, Hypertension, Aging, Blood Pressure
Interventions: IMST, Sham Training; Device
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 50 Years and older
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Healthy Adults, Mechanical Ventilation Dependence, Hypoxia, Exercise Training, Exercise Intolerance, Dietary Supplement, Nitrate Supplementation, Inspiratory Muscle Training
Interventions: Respiratory Muscle Training (RMT), Sham Respiratory Muscle Training, Dietary Supplement: Beetroot Juice Concentrate, placebo beverage; Device · Dietary Supplement
Lead sponsor: Embry-Riddle Aeronautical University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Daytona Beach, Florida

Conditions: Covid19
Interventions: Strength RMT, Strength RMT and nasal breathing, Endurance RMT, Endurance RMT and nasal breathing, Low dose RMT; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 2,268 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Scottsdale, Arizona

Conditions: Exercise Induced Bronchospasm, Exercise Induced Asthma
Interventions: PrO2Fit Device; Device
Lead sponsor: Indiana University; Other
Eligibility: 18 Years to 35 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Bloomington, Indiana

Conditions: Blood Pressure, Vascular Function, Adherence, Treatment
Interventions: App-Based Inspiratory Muscle Strength Training, Clinic-Based Inspiratory Muscle Strength Training; Device
Lead sponsor: University of Colorado, Boulder; Other
Eligibility: 18 Years and older
Enrollment: 33 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Boulder, Colorado

Search by objective public record fields.

IMST for Dementia Risk Reduction

Inspiratory Muscle Training Using the O2 Trainer

A Trial Assessing the Safety and Feasibility of Respiratory Muscle Training and Exercise Training in Children and Adolescents With Persistent Asthma

Effects of Inspiratory Muscle Training in Persons With Advanced Multiple Sclerosis

Inspiratory Muscle Strength Training in Adults With Obesity

Diaphragm Structure and Function in Children

Effects of High-Resistance Inspiratory Muscle Strength Training on Cardiorenal and Vascular Function in Youth and Young Adults With Type 2 Diabetes

Inspiratory Muscle Training Immediately After Lung Transplantation

Dose-Response Effects of Inspiratory Muscle Strength Training on Blood Pressure and Vascular Function

A Study Investigating the Impact of IMT With CR On Exercise Responses In HF

A Study to Evaluate Breathing Muscle Training in Cardiac Rehab

Inspiratory Muscle Training in Ventilator Dependent Patients

Improving Sympathetic Activity, Hot Flashes, and Sleep in Midlife Women Using Inspiratory Muscle Strength Training

Inspiratory Muscle Strength Training to Improve Blood Pressure and Physiological Function

Effect of Inspiratory Muscle Training on Physiological Function and Clinical Outcomes After Lung Transplant

Inspiratory Muscle Training for Breast Cancer Patients on Chemotherapy

A Randomized, Controlled Trial of Inspiratory Muscle Training (IMT)in the ICU and CCU

The Impact of Aerobic Interval and Inspiratory Muscle Training On Patient Reported Outcome Scores In Individuals With Chronic Constipation

Targeted Prehabilitation With Physical Exercise and Inspiratory Muscle Training for Elderly Frail Patients Prior to Ventral Hernia Repair

Inspiratory Muscle Strength Training in Chronic Kidney Disease

Effects of Breathing Training and Nitrate on Exercise at Simulated Altitude

Covid-19 Virtual Recovery Study

Inspiratory Muscle Training on The Severity of Exercise-Induced Bronchoconstriction and Time-Trial Performance (IMT_EIB)

Smartphone App-guided Inspiratory Muscle Strength Training for Lowering Systolic Blood Pressure