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ClinicalTrials.gov public records Last synced Nov 15, 2026, 8:07 AM EST

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Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Instability, Joint Clear all

Conditions: Hypermobile Ehlers-Danlos Syndrome, Heavy Menstrual Bleeding, Hypermobility Syndrome (Disorder)
Interventions: Not listed
Lead sponsor: St. Jude Children's Research Hospital; Other
Eligibility: 12 Years to 40 Years · Female only
Enrollment: 15 participants
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Osteoarthritis
Interventions: functional exercise training; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 50 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Blood Pressure, HDL Low, Stress, Lung Function Decreased, Quality of Life, Energy Supply; Deficiency, Concentration Ability Impaired, Joint Instability, Immune Deficiency
Interventions: Stem Cell 100+; Dietary Supplement
Lead sponsor: Centagen, Inc.; Industry
Eligibility: 35 Years to 80 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016
U.S. locations: 1
States / cities: San Diego, California

Conditions: Patellar (or Kneecap) Instability and Mal-alignment
Interventions: Not listed
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 16 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 2
States / cities: Amherst, New York • Orchard Park, New York

Conditions: Knee Osteoarthritis
Interventions: VERASENSE; Procedure
Lead sponsor: Orthosensor, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Fort Lauderdale, Florida

Conditions: Other Instability, Shoulder, Dislocations, Subluxations, Recurrent Dislocation of Shoulder Region
Interventions: Not listed
Lead sponsor: Carolyn M Hettrich; Other
Eligibility: 12 Years to 99 Years
Enrollment: 1,733 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2042
U.S. locations: 11
States / cities: San Francisco, California • Boulder, Colorado • Iowa City, Iowa + 8 more

Conditions: Patellar Dislocation, Recurrent, Patellar Dislocation, Patellar Instability, Patellofemoral Dislocation, Patellofemoral Joint Dislocation, Patellofemoral Disorder
Interventions: Medial Patellofemoral Ligament (MPFL) Reconstruction; Procedure
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 10 Years to 35 Years
Enrollment: 850 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2027
U.S. locations: 16
States / cities: Redwood City, California • Gainesville, Florida • Chicago, Illinois + 10 more

Conditions: Elbow Joint Destruction, Post-traumatic Lesions, Ankylosed Joints, Advanced Rheumatoid Arthritis, Joint Instability or Loss of Motion, Acute Comminuted Articular Fracture of Elbow Joint Surfaces, Bone Loss Contributing to Elbow Instability, Bilateral Ankylosis From Causes Other Than Active Sepsis, Post-traumatic Arthritis, Degenerative Arthritis
Interventions: Nexel Total Elbow; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 18 Years and older
Enrollment: 134 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2036
U.S. locations: 4
States / cities: Golden, Colorado • Charlotte, North Carolina • Philadelphia, Pennsylvania + 1 more

Conditions: Joint Instability
Interventions: Linvatec 4.5 mm Smart Screw, Synthes 4.0 mm steel screw; Device
Lead sponsor: Rothman Institute Orthopaedics; Other
Eligibility: 18 Years to 75 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2016
U.S. locations: 2
States / cities: Media, Pennsylvania • Philadelphia, Pennsylvania

Conditions: Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction, Joint Instability
Interventions: Anterior cruciate ligament reconstruction (ACLR), Lateral extra-articular tenodesis (LET); Procedure
Lead sponsor: University of Pittsburgh; Other
Eligibility: 14 Years to 25 Years
Enrollment: 1,272 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2028
U.S. locations: 14
States / cities: Redwood City, California • San Francisco, California • Orlando, Florida + 11 more

Conditions: Hip Dysplasia, Hip Pain Chronic, Hip Osteoarthritis, Hip Arthritis, Psychosocial Problem
Interventions: Cell Phone Based Cognitive Based Therapy (Pacifica App), Control; Device · Other
Lead sponsor: Michael C Willey; Other
Eligibility: 15 Years to 39 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Ankle Inversion Sprain, Chronic Instability of Joint
Interventions: Joint Mobilization, Massage; Other
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 35 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Ankle Sprain, Ankle Injuries, Sprain
Interventions: proximal tibiofibular manipulation, distal tibiofibular manipulation, no intervention; Other
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years to 50 Years
Enrollment: 61 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Ligament Injury, Ligament; Laxity, Tendon Rupture, Tendon Injuries
Interventions: methylsulfonylmethane, Placebo; Dietary Supplement · Other
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years to 30 Years · Female only
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Davis, California

Conditions: Ankle Sprain
Interventions: Small amplitude (Grade IV) mobilization, High velocity, low amplitude (Grade V) mobilization; Other
Lead sponsor: Creighton University; Other
Eligibility: 19 Years to 45 Years · Male only
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Arthritis, Unstable Radial Head, Proximal Radioulnar Joint Instability, Decreased Motion at the Proximal Radioulnar Joint and/or the Radio-humeral Joint
Interventions: Aptis PRUJ Prosthesis; Device
Lead sponsor: Aptis Medical; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 84 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2030
U.S. locations: 7
States / cities: Carmel, Indiana • Louisville, Kentucky • Boston, Massachusetts + 4 more

Conditions: Healthy
Interventions: Not listed
Lead sponsor: National Center for Research Resources (NCRR); NIH
Eligibility: 15 Years to 23 Years
Healthy volunteers: Accepts healthy volunteers
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Ankle Injuries, Sprains and Strains, Joint Instability
Interventions: Hyperarch Fascia Training; Behavioral
Lead sponsor: Applied Science & Performance Institute; Industry
Eligibility: 20 Years to 45 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Headache
Interventions: No intervention will be administered. We are only performing tests and measures.; Other
Lead sponsor: Des Moines University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 82 participants
Timeline: 2020 – 2022
U.S. locations: 7
States / cities: Hartford, Connecticut • Des Moines, Iowa • Lafayette, New Jersey + 4 more

Conditions: Physical Endurance, Hypermobility, Joint, Muscular Weakness
Interventions: lateral neck flexor endurance test; Other
Lead sponsor: University of Hartford; Other
Eligibility: 18 Years to 60 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021
U.S. locations: 1
States / cities: West Hartford, Connecticut

Conditions: Shoulder Dislocation, Glenohumeral Dislocation, Anterior Shoulder Dislocation
Interventions: Arthroscopic Bankart repair procedure, Open Bankart, Latarjet, Post-Operative Rehabilitation; Procedure · Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 17 Years to 50 Years
Enrollment: 450 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2027
U.S. locations: 15
States / cities: Tempe, Arizona • San Diego, California • Vail, Colorado + 12 more

Conditions: Shoulder Pain
Interventions: ibuprofen 600 mg, Oxycodone/acetaminophen (Percocet) 5 mg/325; Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: New York, New York

Conditions: Arthroplasty, Replacement
Interventions: Investigational Arm: SMR Stemless Reverse, Control Arm: SMR Reverse Shoulder System; Device
Lead sponsor: Limacorporate S.p.a; Industry
Eligibility: 22 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2028
U.S. locations: 13
States / cities: Los Angeles, California • Denver, Colorado • Boca Raton, Florida + 9 more

Conditions: Primary Knee Arthroplasty
Interventions: ATTUNE Revision Knee System in Total Knee Arthroplasty; Device
Lead sponsor: DePuy Orthopaedics; Industry
Eligibility: 22 Years to 80 Years
Enrollment: 400 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2030
U.S. locations: 15
States / cities: San Diego, California • Denver, Colorado • Fort Collins, Colorado + 12 more

Search by objective public record fields.

Identifying the Determinants of Bleeding and Hypermobility in Patients With Heavy Menstrual Bleeding

Exercise Intervention to Reduce Postural Instability in Osteoarthritis

Effects of a 10 Component Dietary Supplement on Health and the Quality of Life

CT Analysis of the Patellofemoral Joint in Patients Having Knee Surgery

Using Intraoperative Sensing Technology to Evaluate Revision Total Knee Arthroplasty

MOON Shoulder Instability-Cohort of Patients Undergoing Operative Treatment.

JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction

Clinical Outcomes Study of the Nexel Total Elbow

A Comparison of Steel and Bioabsorbable Screw Fixation of Lisfranc Foot Injuries

STABILITY 2: Anterior Cruciate Ligament Reconstruction +/- Lateral Tenodesis With Patellar vs Quad Tendon

Psychosocial Interventions for Young Adults With Hip Pain

Mechanisms of Manual Therapies in CAI Patients

Effects of Proximal and Distal Tibiofibular Joint Manipulation on Lower Extremity Muscle Activation, Ankle Range of Motion, and Functional Outcome Scores in Individuals With Chronic Ankle Instability

Methylsulfonylmethane on Knee Laxity

Effect of Joint Mobilization in the Treatment of Chronic Ankle Instability

Aptis PRUJ Prosthesis for the Treatment of Patients With Proximal Radial Ulna Joint Disorders.

The Effect of Estrogen and Progesterone Levels on Knee and Ankle Joint Laxity

Impact of Hyperarch Fascia Training on Ankle Health and Exercise Performance

Musculoskeletal Impairment in Headaches Attributed to Rhinosinusitis

Lateral Neck Flexor Endurance and Hyperlaxity

Open Versus Arthroscopic Stabilization of Shoulder Instability With Subcritical Bone Loss: The OASIS Trial

Multimodal Analgesia With NSAID vs. Narcotics Alone After Shoulder Instability Surgery

SMR Stemless Reverse vs SMR Reverse Shoulder System

ATTUNE® Revision- Complex Primary in Total Knee Arthroplasty Population