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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Insufflation Clear all
Completed Not applicable Interventional Results available

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Use in Pediatric Procedures

NCT03430206
View directory record Official record
Conditions
Oxygen Deficiency, Desaturation of Blood, Hypoventilation, Anesthesia; Adverse Effect
Interventions
High-flow nasal cannula
Device
Lead sponsor
Stanford University
Other
Eligibility
Up to 18 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 5, 2020 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional

Water-aided Colonoscopy vs Air Insufflation Colonoscopy in Colorectal Cancer Screening

NCT02041507
View directory record Official record
Conditions
Colorectal Cancer, Colorectal Adenomas, Colorectal Polyps, Pain
Interventions
Air insufflation method., Water Immersion method., Water Exchange method.
Other
Lead sponsor
Presidio Ospedaliero Santa Barbara
Other
Eligibility
50 Years to 70 Years
Enrollment
1,224 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 12, 2016 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

AirSeal®Insufflation Trocar/CO2 Absorption Study

NCT02654808
View directory record Official record
Conditions
Gynecologic Diseases
Interventions
AirSeal trocar, Standard trocar
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 15, 2021 · Synced Jul 23, 2026, 5:12 AM EDT
Not yet recruiting Not applicable Interventional

Low Gas Pressure vs Standard Gas Pressure in Weight-Loss Surgery

NCT07710352
View directory record Official record
Conditions
Obesity & Overweight, Robotic Surgery, Pneumoperitoneum
Interventions
AirSeal Robotic Solution, Standard-pressure pneumoperitoneum (15 mmHg)
Device · Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional Results available

A Comparative Study Between AirSeal, an Integrated Insufflation System, and Conventional Insufflation

NCT02075658
View directory record Official record
Conditions
Renal Cell Carcinoma
Interventions
AirSeal® System-Interventional, Conventional Insufflator and Trocar
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2014
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Feb 13, 2018 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional

Single Port Insufflation RCT

NCT06990750
View directory record Official record
Conditions
Postoperative Pain Score
Interventions
15 mmHg, 12 mmHg
Procedure
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional

A Comparison of Air Insufflation, Water Immersion and Water Exchange Colonoscopy in CRC Screening

NCT01780818
View directory record Official record
Conditions
Pain, Colorectal Adenomas, Colorectal Cancer
Interventions
Air Insufflation method., Water Immersion method., Water Exchange method.
Other
Lead sponsor
Presidio Ospedaliero Santa Barbara
Other
Eligibility
50 Years to 70 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2014 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Trendelenburg, Abdominal Insufflation and Time to Completion of Cystoscopy

NCT05786391
View directory record Official record
Conditions
Bladder Integrity, Bladder Function, Ureteral Integrity, Ureteral Function
Interventions
Flat position, Trendelenburg position, Insufflation
Other · Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 90 Years · Female only
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 23, 2025 · Synced Jul 23, 2026, 5:12 AM EDT
Not yet recruiting Not applicable Interventional

Comparison of AirSeal to DV5 Insufflation in Gastric Sleeve Procedures - The "CAT5-GS" Study

NCT07312006
View directory record Official record
Conditions
Pain, Postoperative
Interventions
AirSeal Insufflation system, DV5 Insufflation system
Device
Lead sponsor
SurgiQuest, Inc.
Industry
Eligibility
22 Years to 65 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Jul 23, 2026, 5:12 AM EDT
Terminated Phase 3 Interventional Accepts healthy volunteers

Comparison of Adenoma Detection Rate Among Water, Carbon Dioxide and Air Methods of Minimal Sedation Colonoscopy

NCT01782014
View directory record Official record
Conditions
Screening Colonoscopy
Interventions
colonoscopy
Procedure
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 80 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jan 31, 2016 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Phase 4 Interventional Results available

Safety and Efficacy of CO2 for Endoscopy

NCT03287687
View directory record Official record
Conditions
Endoscopy, Insufflation
Interventions
Carbon dioxide (CO2) gas insufflation, Air insufflation
Drug
Lead sponsor
Warren Bishop
Other
Eligibility
6 Months to 21 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional Results available

Is End Tidal CO2 Level Elevation During Upper Endoscopy With CO2 Gas Insufflation Physiologically Significant

NCT04541667
View directory record Official record
Conditions
Endoscopy
Interventions
Air, Carbon Dioxide
Other
Lead sponsor
University of Nebraska
Other
Eligibility
6 Months to 19 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 9, 2023 · Synced Jul 23, 2026, 5:12 AM EDT
Active, not recruiting Phase 2 Interventional Results available

The Effect of Deep Versus Moderate Muscle Relaxants in Men During and After Robotic Surgery for Prostate Cancer

NCT03808077
View directory record Official record
Conditions
Prostate Cancer
Interventions
Rocuronium 0.3mg/kg/hr, Rocuronium 1.5mg/kg/hr
Drug
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years to 80 Years · Male only
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional Results available

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Short Laryngologic Surgery

NCT03091179
View directory record Official record
Conditions
Laryngologic Surgical Procedures
Interventions
THRIVE, Endotracheal tube
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 3, 2020 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigation of Cecal Intubation Rates and Pain Levels Between Water Exchange and Air Insufflation Flexible Sigmoidoscopy

NCT03209349
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Water Exchange Sigmoidoscopy, Air Insufflation Sigmoidoscopy
Procedure
Lead sponsor
Kelowna Gastroenterology Associates
Other
Eligibility
50 Years to 74 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
North Hills, California
Source: ClinicalTrials.gov public record
Updated Nov 6, 2022 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Pneumoinsufflation Modes and Pressure Settings in Gynecology

NCT02853591
View directory record Official record
Conditions
Pain, Pneumoperitoneum, Inflammation, Quality of Life
Interventions
Pneumoinsufflator mode and setting
Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Mar 7, 2023 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

RCT of Air Insufflation Versus Water Infusion Colonoscopy by Supervised Trainees

NCT00841282
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Colonoscopy for colorectal cancer screening, Water Infusion Colonoscopy, Air insufflation colonoscopy
Procedure
Lead sponsor
East Bay Institute for Research and Education
Other
Eligibility
50 Years to 80 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Mather, California
Source: ClinicalTrials.gov public record
Updated Feb 10, 2009 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional

Comparison of Methods to Distend the Colon During Insertion: CO2, Air Insufflation, Water-aided Colonoscopy

NCT01954862
View directory record Official record
Conditions
Pain, Colorectal Adenomas, Colorectal Cancer
Interventions
Air Insufflation method., CO2 insufflation, Water Immersion/CO2, Water Exchange/CO2, Water Immersion/AI, Water Exchange/AI
Other
Lead sponsor
Presidio Ospedaliero Santa Barbara
Other
Eligibility
18 Years to 85 Years
Enrollment
624 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 30, 2014 · Synced Jul 23, 2026, 5:12 AM EDT
Not listed Not applicable Interventional

SurgiQuest AirSeal in Robotic Partial Nephrectomy - (TARPAN Study)

NCT02262884
View directory record Official record
Conditions
Subcutaneous Emphysema
Interventions
SurgiQuest AirSeal Insufflation System (AIS), Conventional Insufflation System (CIS)
Device
Lead sponsor
SurgiQuest, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
189 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
3
States / cities
St Louis, Missouri • Hackensack, New Jersey • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 5, 2016 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional Results available

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Laser Laryngeal Surgery

NCT03086265
View directory record Official record
Conditions
Otorhinolaryngologic Surgical Procedures, Laser Therapy
Interventions
THRIVE, Endotracheal tube
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 16, 2020 · Synced Jul 23, 2026, 5:12 AM EDT
Active, not recruiting Not applicable Interventional

Mechanical Insufflation in the Philadelphia Amyotrophic Lateral Sclerosis Cohort (MI-PALS) Study

NCT06119087
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis, Chronic Respiratory Failure, Airway Clearance Impairment, Neuromuscular Diseases
Interventions
Mechanical insufflation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Jul 23, 2026, 5:12 AM EDT
Not yet recruiting Not applicable Interventional

Pneumoperitoneum Management With SurgiQuest AirSeal® at Low vs. Higher Pressure

NCT02837601
View directory record Official record
Conditions
Shoulder Pain
Interventions
AirSeal® Insufflation System (AIS)
Device
Lead sponsor
Akron Children's Hospital
Other
Eligibility
Up to 21 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 12, 2020 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional

Carbon Dioxide Insufflation Versus Conventional Air Insufflation

NCT02790359
View directory record Official record
Conditions
Abdominal Pain
Interventions
Air, Carbon dioxide
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
8 Years to 21 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 12, 2019 · Synced Jul 23, 2026, 5:12 AM EDT
Completed Not applicable Interventional

Veress Entry With/Without Concomitant CO2

NCT02896036
View directory record Official record
Conditions
Laparoscopy, Laparoscopic Surgery, Insufflation, Gynecologic Surgical Procedures
Interventions
Veress needle entry with concomitant CO2, Veress needle entry with subsequent CO2
Procedure
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 29, 2018 · Synced Jul 23, 2026, 5:12 AM EDT