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ClinicalTrials.gov public records Last synced Nov 4, 2026, 11:41 AM EST

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Showing 1–23 of 23 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Insulin Homeostasis Clear all

Conditions: Pre Diabetes
Interventions: Hyperinsulemic euglycemic clamp, Muscle Biopsy, Oral abscisic acid (ABA), Placebo; Other · Procedure · Dietary Supplement
Lead sponsor: AdventHealth Translational Research Institute; Other
Eligibility: 18 Years to 65 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Orlando, Florida

Conditions: Type 2 Diabetes Mellitus, Obesity
Interventions: Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric Banding, Lifestyle Weight Loss Intervention; Procedure · Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 25 Years to 55 Years
Enrollment: 69 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2028
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Insulin Resistance
Interventions: Novel dietary fiber, Placebo; Other
Lead sponsor: Cargill; Industry
Eligibility: 30 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Diabetes Mellitus
Interventions: Aldosterone infusion (A), Vehicle Infusion (V), High Sodium Diet (HS), Low Sodium Diet (LS); Drug · Other
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years to 70 Years
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2013
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Diabetes, Prediabetic, Prediabetes, Glucose Intolerance
Interventions: eszopiclone; Drug
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 64 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Healthy, Insulin Resistance
Interventions: Ultrasound; Procedure
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 60 Years
Enrollment: 37 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Obesity, Insulin Resistance, Vitamin D Deficiency
Interventions: Vitamin D3; Drug
Lead sponsor: Perrin C White, MD; Other
Eligibility: 6 Years to 17 Years
Enrollment: 109 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Morbid Obesity
Interventions: gastric bypass, gastric banding, sleeve gastrectomy; Procedure
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 20 Years to 70 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2018
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Bone Mineral Density, Body Fat Distribution, Insulin Homeostasis
Interventions: Not listed
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 5 Years to 10 Years · Female only
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Continuous Glucose Monitoring, Oral Glucose Tolerance, Insulin Sensitivity, Inflammatory Markers
Interventions: Non-Nutritive Sweetener Intake and impact on glucose homeostasis; Other
Lead sponsor: Virginia Polytechnic Institute and State University; Other
Eligibility: 40 Years and older
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Blacksburg, Virginia

Conditions: Obesity, PreDiabetes
Interventions: ADI-PEG20, Placebo; Biological · Other
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 22 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Insulin Sensitivity, Oxidative Stress
Interventions: Galantamine, Placebo; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 60 Years · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Polycystic Ovary Syndrome, Insulin Resistance
Interventions: walnuts, almonds; Dietary Supplement
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Mather, California

Conditions: Metabolic Syndrome, Pre-Diabetes
Interventions: Time Restricted Eating + Standard of Care, Standard of Care; Behavioral
Lead sponsor: University of California, San Diego; Other
Eligibility: 18 Years to 75 Years
Enrollment: 122 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Glucose Intolerance, Type 2 Diabetes Mellitus, Metabolic Syndrome
Interventions: Vitamin D3 2,000 IU orally once daily, Calcium Carbonate 400 mg orally twice daily, Vitamin D3-Placebo, Calcium-Placebo; Drug
Lead sponsor: Tufts Medical Center; Other
Eligibility: 40 Years and older
Enrollment: 92 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2009
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Bypass, Gastric, Roux-en-Y Gastric Bypass, Vertical Sleeve Gastrectomy, Gastric Banding, Bariatric Surgery
Interventions: Placebo, Lo-Xenin, Hi-Xenin, Extra Hi-Xenin; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 65 Years
Enrollment: 13 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Glucose Homeostasis
Interventions: Placebo, Januvia; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 21 Years to 75 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Type 2 Diabetes Mellitus
Interventions: Placebo, Bethanechol (25 mg), Bethanechol (50 mg), Bethanechol (100 mg); Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 65 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Glucose Intolerance, Insulin Resistance, Iron Metabolism
Interventions: Blood Donation; Procedure
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 40 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Insulin Resistance, Metabolic Syndrome, Obesity, Diabetes, NAFLD, Inflammation
Interventions: Limited dairy diet, Low-fat dairy diet, Full-fat dairy diet; Other
Lead sponsor: Fred Hutchinson Cancer Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 72 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Continuous Glucose Monitoring, Oral Glucose Tolerance, Insulin Sensitivity, Inflammatory Markers
Interventions: Non-Nutritive Sweetener Intake and impact on glucose homeostasis; Other
Lead sponsor: Virginia Polytechnic Institute and State University; Other
Eligibility: 40 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Blacksburg, Virginia

Conditions: Metabolic Syndrome
Interventions: Sildenafil citrate, Placebo Oral Capsule; Drug
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Insulin Sensitivity, 24-hour Glucose Control
Interventions: HIgh UPF controlled diet, No UPF controlled diet; Other
Lead sponsor: Virginia Polytechnic Institute and State University; Other
Eligibility: 40 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Blacksburg, Virginia

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Abscisic Acid Effects on Glucose Homeostasis and Insulin Sensitivity

The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes

Effects of Novel Fiber on Glucose Homeostasis in Individuals at Risk for Diabetes

Aldosterone and Glucose Homeostasis

Sleep Effectiveness and Insulin and Glucose Homeostasis

Effects of Hepatic Ultrasound on Metabolic Homeostasis

Correction of Vitamin D Levels and Its Effect on Insulin Resistance and Weight Gain in Obese Youth

Glucose Homeostasis Pre and Post Bariatric Surgery

The Bone-Fat-Pancreas Axis in Children

Non-Nutritive Sweetener Consumption and Glucose Homeostasis in Older Adults With Prediabetes

ADI-PEG20, Obesity and Prediabetes

Racial Differences in Vagal Control of Glucose Homeostasis, Chronic Study

The Effects of Walnuts, Walnut-Oil, Almonds and Fish Oils on Glucose Homeostasis in Polycystic Ovary Syndrome

The Influence of Time-Restricted Eating in Patients With Metabolic Syndrome

Vitamin D and Calcium Homeostasis for Prevention of Type 2 Diabetes

To Define the Role of GLP-1 for Improving Glucose Homeostasis in Humans Following Gastric Bypass Surgery

Dipeptidyl Peptidase-4 Inhibition on Glucagon-like Peptide-1 (GLP-1)

The Effects of Bethanechol on Glucose Homeostasis

Iron and Insulin Resistance in Overweight and Obese Humans

The Impact of Low-fat and Full-fat Dairy Consumption on Glucose Homeostasis (DAIRY Study)

Saccharin and Acesulfame Potassium Consumption and Glucose Homeostasis in Older Adults With Prediabetes

Effect of Prolonged PDE-5 Inhibition on Insulin Signaling in Skeletal Muscle.

Ultra-processed Food Consumption, Gut Microbiota, and Glucose Homeostasis