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Showing 1–24 of 1,672 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Insulin Resistance Clear all
Completed Phase 2 Interventional Results available

Atorvastatin in New Onset Type 1 Diabetes Mellitus (T1DM)

NCT00529191
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Atorvastatin, Placebo
Drug · Other
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
10 Years to 19 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 12, 2017 · Synced Jun 7, 2026, 3:16 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Comparison of Two Different Diets on Health Outcomes

NCT00269646
View directory record Official record
Conditions
Metabolic Syndrome X
Interventions
Low-carbohydrate and high-carbohydrate diets
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 64 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 17, 2009 · Synced Jun 7, 2026, 3:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Glycemic Index - Variability Among Individuals

NCT01023646
View directory record Official record
Conditions
Diabetes, Obesity, Metabolic Syndrome, Cardiovascular Disease
Interventions
Carbohydrate + Protein, Carbohydrate + Fat, Fiber, Carbohydrate load
Other
Lead sponsor
Tufts University
Other
Eligibility
18 Years to 85 Years
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2017 · Synced Jun 7, 2026, 3:16 AM EDT
Recruiting Not applicable Interventional

Safety Evaluation of MODI, an Insulin Titration Algorithm, in Adults With Diabetes

NCT07599982
View directory record Official record
Conditions
Type 1 Diabetes (T1D), Type 2 Diabetes (T2D)
Interventions
MODI Algorithm
Device
Lead sponsor
DreaMed Diabetes
Industry
Eligibility
18 Years to 80 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
3
States / cities
Albany, New York • Austin, Texas • Sandy City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jun 7, 2026, 3:16 AM EDT
Completed Phase 4 Interventional Results available

Testosterone Replacement in Men With Diabetes and Obesity

NCT01127659
View directory record Official record
Conditions
Hypogonadism
Interventions
testosterone, placebo
Drug
Lead sponsor
University at Buffalo
Other
Eligibility
30 Years to 65 Years · Male only
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Williamsville, New York
Source: ClinicalTrials.gov public record
Updated Nov 28, 2022 · Synced Jun 7, 2026, 3:16 AM EDT
Completed Not applicable Interventional

Evaluation of Medium Chain Triglycerides in a Mixed Racial Population of Patients: a Feasibility Study

NCT02783703
View directory record Official record
Conditions
Insulin Resistance
Interventions
Medium chain triglycerides (MCT)
Dietary Supplement
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 29, 2019 · Synced Jun 7, 2026, 3:16 AM EDT
Completed Not applicable Interventional

The Effects of Strawberries on Blood Cholesterol.

NCT03441620
View directory record Official record
Conditions
Hyper-LDL-cholesterolemia, Metabolic Syndrome
Interventions
strawberries, Control powder
Dietary Supplement · Other
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
3
States / cities
Las Vegas, Nevada • Oklahoma City, Oklahoma • Stillwater, Oklahoma
Source: ClinicalTrials.gov public record
Updated Mar 15, 2021 · Synced Jun 7, 2026, 3:16 AM EDT
Completed Phase 4 Interventional

The Effects of Aripiprazole on Patients With Metabolic Syndrome

NCT00224822
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Metabolic Syndrome X
Interventions
Aripiprazole
Drug
Lead sponsor
New Mexico VA Healthcare System
Federal
Eligibility
18 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Mar 23, 2010 · Synced Jun 7, 2026, 3:16 AM EDT
Completed Phase 4 Interventional Results available

A Clinical Trial to Prevent New Onset Diabetes After Transplantation

NCT01683331
View directory record Official record
Conditions
Prevention of New Onset Diabetes Among Kidney Transplant Patients
Interventions
Insulin treatment for hyperglycemia
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
251 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 19, 2019 · Synced Jun 7, 2026, 3:16 AM EDT
Recruiting Not applicable Interventional

UTSW NORC Pilot Spinal Cord Injury Dietary Program

NCT06924177
View directory record Official record
Conditions
Obesity and Obesity-related Medical Conditions, Spinal Cord Injury, Chronic
Interventions
Telehealth with dietician
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Jun 7, 2026, 3:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Vestibular Stimulation to Trigger Adipose Loss (VeSTAL) Clinical Trial

NCT03640286
View directory record Official record
Conditions
Obesity
Interventions
VeSTAL
Device
Lead sponsor
Neurovalens Ltd.
Industry
Eligibility
22 Years to 80 Years
Enrollment
241 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
3
States / cities
La Jolla, California • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Jun 7, 2026, 3:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Vitamin D Repletion on Insulin Resistance

NCT00606957
View directory record Official record
Conditions
Obesity
Interventions
Vitamin D3 (cholecalciferol)
Dietary Supplement
Lead sponsor
Rockefeller University
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 12, 2011 · Synced Jun 7, 2026, 3:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Glycemic Effects of Honey

NCT01371266
View directory record Official record
Conditions
Pre-diabetes
Interventions
Honey, High Fructose Corn Syrup 55 (HFCS 55), CHO (sugar)
Dietary Supplement
Lead sponsor
USDA Grand Forks Human Nutrition Research Center
Federal
Eligibility
20 Years to 80 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated Aug 2, 2018 · Synced Jun 7, 2026, 3:16 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effect of Nesiritide Infusion on Insulin Sensitivity in Healthy Obese Insulin Resistant Subjects

NCT03234751
View directory record Official record
Conditions
Diabetes
Interventions
Continous IV infusion of Nesiritide, Hyperinsulinemic euglycemic clamp, Placebo
Drug
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
40 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Mar 9, 2020 · Synced Jun 7, 2026, 3:16 AM EDT
Terminated Phase 1Phase 2 Interventional Accepts healthy volunteers

A Phase 1/2 Study to Evaluate ALN-KHK in Overweight to Obese Healthy Volunteers and Obese Patients With T2DM

NCT05761301
View directory record Official record
Conditions
Type 2 Diabetes Mellitus (T2DM)
Interventions
ALN-KHK, Placebo
Drug
Lead sponsor
Alnylam Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
11
States / cities
Phoenix, Arizona • Vista, California • Lake Worth, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced Jun 7, 2026, 3:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Racial Differences in the Natriuretic Peptide Response to Glucose Challenge

NCT03072602
View directory record Official record
Conditions
Healthy, Natriuretic Peptides, Metabolic Syndrome
Interventions
Study diet, Glucose Challenge
Dietary Supplement · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 40 Years
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 21, 2023 · Synced Jun 7, 2026, 3:16 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Effect of Resveratrol on Age-related Insulin Resistance and Inflammation in Humans

NCT01354977
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Insulin Resistance
Interventions
Resveratrol
Drug
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
45 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2017
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Mar 7, 2022 · Synced Jun 7, 2026, 3:16 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Vitamin K and Glucose Metabolism in Adults at Risk for Diabetes (Vita-K 'n' Adults Study)

NCT02366481
View directory record Official record
Conditions
Obesity, Insulin Resistance, Insulin Sensitivity, Beta-Cell Dysfunction, Prediabetes
Interventions
Placebo, Low-Dose Vitamin K2 Supplement (menaquinone-7; 90-mcg/d), High-Dose Vitamin K2 Supplement (menaquinone-7; 180-mcg/d)
Dietary Supplement
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Nov 19, 2019 · Synced Jun 7, 2026, 3:16 AM EDT
Completed Not applicable Interventional

Nutrition to Optimize, Understand, and Restore Insulin Sensitivity in HIV for Oklahoma

NCT05208671
View directory record Official record
Conditions
HIV, Insulin Resistance, Food Insecurity
Interventions
NOURISH Food Box
Other
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
675 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Tulsa, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Jun 7, 2026, 3:16 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Effect of Vitamin D Repletion on Insulin Resistance and Systemic Inflammation

NCT01354964
View directory record Official record
Conditions
Insulin Resistance
Interventions
Vitamin D, Placebo
Drug
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
21 Years to 75 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Nov 1, 2020 · Synced Jun 7, 2026, 3:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Learning to BREATHE: A Randomized Controlled Trial to Lower Diabetes Risk in Adolescent Girls

NCT02218138
View directory record Official record
Conditions
Type 2 Diabetes, Depression, Obesity
Interventions
Learning 2 BREATHE, Colorado Blues
Behavioral
Lead sponsor
Colorado State University
Other
Eligibility
12 Years to 17 Years · Female only
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 11, 2020 · Synced Jun 7, 2026, 3:16 AM EDT
Completed Not applicable Interventional Results available

Regular Insulin vs Rapid Insulin Delivered by V-Go

NCT03495908
View directory record Official record
Conditions
Type 2 Diabetes, Type 2 Diabetes Mellitus
Interventions
VGo
Device
Lead sponsor
East Coast Institute for Research
Network
Eligibility
21 Years and older
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
Jacksonville, Florida • Macon, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 1, 2021 · Synced Jun 7, 2026, 3:16 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Yo-Yo Sleep on Cardiometabolic Health

NCT05880758
View directory record Official record
Conditions
Cardiometabolic Syndrome, Obesity
Interventions
Intermittent Short Sleep (ISS), Social Jetlag (SJL), Sustained Adequate Sleep (SAS)
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 49 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Jun 7, 2026, 3:16 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Chromium and Insulin Resistance

NCT00846248
View directory record Official record
Conditions
Insulin Resistance
Interventions
Chromium, placebo
Dietary Supplement
Lead sponsor
University of California, San Francisco
Other
Eligibility
20 Years to 50 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 30, 2012 · Synced Jun 7, 2026, 3:16 AM EDT