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Showing 1–24 of 709 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Insulin Resistance Syndrome Clear all
Recruiting Not applicable Interventional

Telenutrition for Individuals With SCI

NCT05468437
View directory record Official record
Conditions
Spinal Cord Injuries, Obesity, Cardiometabolic Syndrome
Interventions
Telenutrition
Behavioral
Lead sponsor
Santa Clara Valley Health & Hospital System
Other
Eligibility
20 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated May 15, 2025 · Synced Jul 23, 2026, 12:09 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Strong Families Start at Home/Familias Fuertes Comienzan en Casa

NCT06099288
View directory record Official record
Conditions
Metabolic Syndrome, Protection Against, Diet, Healthy
Interventions
Home-Based Video and Motivational Interviewing Intervention, Read Educate and Develop Youth (READY) Comparison
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
257 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced Jul 23, 2026, 12:09 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Vitamin D for the Treatment of Women With Polycystic Ovary Syndrome (PCOS)

NCT00907153
View directory record Official record
Conditions
Polycystic Ovary Syndrome
Interventions
Vitamin D, Placebo
Dietary Supplement · Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 18, 2017 · Synced Jul 23, 2026, 12:09 AM EDT
Completed Not applicable Interventional

Chromium Picolinate for the Treatment of Metabolic Syndrome

NCT00128154
View directory record Official record
Conditions
Metabolic Syndrome X, Prediabetic State, Insulin Resistance, Obesity, Metabolic Diseases
Interventions
Chromium picolinate
Drug
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years to 75 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 17, 2006 · Synced Jul 23, 2026, 12:09 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Effect of Physical Activity on Metabolic Syndrome in Pregnancy & Fetal Outcome

NCT00647595
View directory record Official record
Conditions
Obesity, Pregnancy, Diabetes Mellitus
Interventions
Experimental group
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 45 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Joint Base Lewis McChord, Washington
Source: ClinicalTrials.gov public record
Updated Apr 21, 2015 · Synced Jul 23, 2026, 12:09 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Health Effects of Liposuction in Overweight Women With Elevated Insulin Levels, Impaired Glucose Tolerance and/or Type 2 Diabetes

NCT00005760
View directory record Official record
Conditions
Glucose Intolerance, Hyperinsulinemia, Diabetes Mellitus, Non Insulin Dependent, Obesity
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 23, 2026, 12:09 AM EDT
Completed Phase 1 Interventional

Alpha Lipoic Acid and Polycystic Ovary Syndrome

NCT00505427
View directory record Official record
Conditions
Insulin Resistance, Oxidative Stress
Interventions
Alpha Lipoic Acid
Dietary Supplement
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 30, 2013 · Synced Jul 23, 2026, 12:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Reduced Carbohydrate Diet Intervention for Polycystic Ovary Syndrome (PCOS)

NCT01028989
View directory record Official record
Conditions
Polycystic Ovary Syndrome
Interventions
Reduced Glycemic Load Diet, Standard Diet
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 50 Years · Female only
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 14, 2013 · Synced Jul 23, 2026, 12:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Re-energize With Nutrition, Exercise and Weight Loss

NCT00712127
View directory record Official record
Conditions
Obesity
Interventions
Diet and Exercise, Diet and Exercise-Delayed
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
30 Years to 55 Years
Enrollment
310 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2010
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 30, 2017 · Synced Jul 23, 2026, 12:09 AM EDT
Recruiting Not applicable Interventional

A Study Of Milk Consumption In Metabolic Syndrome

NCT07401888
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Full-fat diet, Low-fat diet
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Jul 23, 2026, 12:09 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Northern Manhattan Study of Metabolism and Mind

NCT02470260
View directory record Official record
Conditions
Diabetes, Pre-diabetes, Cognition - Other, Depressive Symptoms, Metabolic Syndrome
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
50 Years to 64 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced Jul 23, 2026, 12:09 AM EDT
Completed Phase 2 Interventional Results available

Comparison of Aliskiren and Amlodipine on Insulin Resistance and Endothelial Dysfunction in Patients With Hypertension and Metabolic Syndrome

NCT00417170
View directory record Official record
Conditions
High Blood Pressure, Metabolic Syndrome, Insulin Resistance, Endothelial Dysfunction
Interventions
Aliskiren, Amlodipine, Placebo Aliskiren, Placebo Amlodipine
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Sep 25, 2011 · Synced Jul 23, 2026, 12:09 AM EDT
Completed Phase 2 Interventional Results available

Effects of Human Leptin Replacement

NCT00657605
View directory record Official record
Conditions
Obesity, Metabolic Syndrome, Diabetes
Interventions
Recombinant methionyl human leptin
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 80 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2010
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 12, 2020 · Synced Jul 23, 2026, 12:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cellular Dynamics of Subcutaneous Fat Distribution in Obese Women

NCT01748994
View directory record Official record
Conditions
Obesity, Metabolic Syndrome
Interventions
Pioglitazone, Placebo
Drug
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
2
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 29, 2021 · Synced Jul 23, 2026, 12:09 AM EDT
Active, not recruiting No phase listed Observational

Using Secondary Data to Evaluate Sex-based Heterogeneity of GLP-1 Agonists and SGLT2 Inhibitors on Cardiovascular-Kidney-Metabolic Health (CKMH) Outcomes in Real-world Settings (DASH-CKMH)

NCT07188545
View directory record Official record
Conditions
Cardiovascular Kidney Metabolic Syndrome
Interventions
Intervention, Active Comparator
Drug
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
23,280,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Jul 23, 2026, 12:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Dietary Flavonoids on Intestinal Microbiota, Intestinal Inflammation and Metabolic Syndrome

NCT02728570
View directory record Official record
Conditions
Metabolic Syndrome X, Inflammation
Interventions
High Dietary Flavonoids, Low Dietary Flavonoids
Other
Lead sponsor
Utah State University
Other
Eligibility
18 Years to 70 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Logan, Utah
Source: ClinicalTrials.gov public record
Updated Apr 14, 2016 · Synced Jul 23, 2026, 12:09 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Determine How Consumption of Dairy Fat Fractions Rich in Phospholipids and Proteins Influence Inflammation in the Fed State-Phase 1

NCT01811329
View directory record Official record
Conditions
Metabolic Syndrome, Obesity
Interventions
Dairy fat, Dairy fat + MFGM, Palm fat, Palm fat + MFGM
Dietary Supplement
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 65 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2027
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Jul 23, 2026, 12:09 AM EDT
Withdrawn No phase listed Observational

Hispanics With Metabolic Syndrome and Non-ischemic Heart Failure

NCT00804882
View directory record Official record
Conditions
Metabolic Syndrome, Heart Failure
Interventions
Not listed
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 59 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Apr 12, 2015 · Synced Jul 23, 2026, 12:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Phosphorus Additives on the Metabolome in Healthy Adults

NCT03841786
View directory record Official record
Conditions
Metabolic Syndrome, Insulin Sensitivity, Cardiovascular Diseases
Interventions
Phosphorus-supplemented study diet, Control Diet
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 45 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 28, 2022 · Synced Jul 23, 2026, 12:09 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Does Antidepressant Use Blunt Adaptations to Exercise?

NCT03934723
View directory record Official record
Conditions
Depression, Depressive Disorder, Metabolic Syndrome
Interventions
Exercise
Behavioral
Lead sponsor
California State University, San Marcos
Other
Eligibility
18 Years to 40 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Marcos, California
Source: ClinicalTrials.gov public record
Updated Jul 22, 2019 · Synced Jul 23, 2026, 12:09 AM EDT
Completed Phase 2 Interventional Results available

Safety, Tolerability, and Efficacy of Saroglitazar Mg 4 mg in Liver Transplant Recipients With Nonalcoholic Fatty Liver Disease (NAFLD)

NCT03639623
View directory record Official record
Conditions
Liver Transplant; Complications, NAFLD
Interventions
Saroglitazar
Drug
Lead sponsor
Zydus Therapeutics Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 23, 2024 · Synced Jul 23, 2026, 12:09 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Polycystic Ovary Syndrome (PCOS) and Sleep Apnea

NCT00203996
View directory record Official record
Conditions
Polycystic Ovary Syndrome, Obstructive Sleep Apnea
Interventions
continuous positive airway pressure (CPAP), depot leuprolide plus estrogen/progestin replacement, pioglitazone, REM frag, SWS supp
Device · Drug · Procedure
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 40 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 20, 2023 · Synced Jul 23, 2026, 12:09 AM EDT
Active, not recruiting Not applicable Interventional

Influence of Metabolic Syndrome on Endogenous Oxalate Synthesis

NCT06735924
View directory record Official record
Conditions
MASLD, Metabolic Dysfunction-Associated Steatotic Liver Disease
Interventions
Low-oxalate fixed diet
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Jul 23, 2026, 12:09 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Partnership Programs to Reduce Ethnic Differences in the Risk of Cardiovascular Disease

NCT00101517
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, Obesity, Metabolic Syndrome X
Interventions
Not listed
Lead sponsor
Emory University
Other
Eligibility
30 Years to 78 Years
Enrollment
4,024 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 15, 2014 · Synced Jul 23, 2026, 12:09 AM EDT