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ClinicalTrials.gov public records Last synced Oct 12, 2026, 3:50 PM EDT

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Showing 337–360 of 714 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Insulin Resistance Syndrome Clear all
Completed No phase listed Observational Accepts healthy volunteers

Research Study for Children With a Mother or Sister With Polycystic Ovary Syndrome

NCT00559390
View directory record Official record
Conditions
Precursors to PCOS
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
8 Years to 12 Years · Female only
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 5, 2013 · Synced Oct 12, 2026, 3:50 PM EDT
Completed Not applicable Interventional Results available

The Influence of Time-Restricted Eating in Patients With Metabolic Syndrome

NCT04057339
View directory record Official record
Conditions
Metabolic Syndrome, Pre-Diabetes
Interventions
Time Restricted Eating + Standard of Care, Standard of Care
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 75 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 12, 2026, 3:50 PM EDT
Recruiting Phase 1Phase 2 Interventional

Probiotics and Gut Health

NCT03418857
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Yogurt smoothie with BB-12, Yogurt smoothie
Drug
Lead sponsor
Penn State University
Other
Eligibility
55 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 14, 2021 · Synced Oct 12, 2026, 3:50 PM EDT
Completed Not applicable Interventional Results available

The HOMBRE Trial: Comparing Two Innovative Approaches to Reduce Chronic Disease Risk Among Latino Men

NCT03092960
View directory record Official record
Conditions
Obesity, Metabolic Syndrome, Lifestyle Intervention, Pre Diabetes
Interventions
Minimal intensity intervention, HOMBRE
Behavioral
Lead sponsor
Palo Alto Medical Foundation
Other
Eligibility
18 Years and older · Male only
Enrollment
424 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Nov 17, 2021 · Synced Oct 12, 2026, 3:50 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Study of the Function of Hormones Present In Taste Buds

NCT00233298
View directory record Official record
Conditions
Diabetes, Obesity, Pre-Diabetes, Metabolic Syndrome
Interventions
Not listed
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
12 Years to 50 Years
Enrollment
225 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 12, 2026, 3:50 PM EDT
Completed Not applicable Interventional Results available

Optimizing Individual Nutrition in Preterm Very Low Birth Weight Infants

NCT02372136
View directory record Official record
Conditions
Infant, Premature, Diseases, Infant, Small for Gestational Age
Interventions
Individualized Nutrition, Optimized nutrition
Dietary Supplement
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
Up to 7 Days
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 12, 2026, 3:50 PM EDT
Completed Phase 2 Interventional Results available

Polyunsaturated Fatty Acids (PUFA) in Diabetic Fatty Liver

NCT00323414
View directory record Official record
Conditions
Fatty Liver
Interventions
Polyunsaturated fatty acid (Opti-EPA), Placebo
Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
2
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 23, 2018 · Synced Oct 12, 2026, 3:50 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes (OPTIMAL)

NCT06605898
View directory record Official record
Conditions
Cognitive Change, Diet, Healthy, Metabolic Syndrome, Protection Against
Interventions
MIND Diet, Control Diet
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
45 Years to 64 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 20, 2024 · Synced Oct 12, 2026, 3:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Pasta on Blood Glucose Response in Normal Subjects

NCT01469312
View directory record Official record
Conditions
Blood Glucose Concentration, Type 2 Diabetes, Metabolic Syndrome
Interventions
modified pasta
Other
Lead sponsor
Minneapolis Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 11, 2011 · Synced Oct 12, 2026, 3:50 PM EDT
Not listed No phase listed Observational

Body Composition Assessment in Spinal Cord Injury

NCT00957762
View directory record Official record
Conditions
Diabetes Mellitus, Body Composition, Tetraplegia, Paraplegia, Spinal Cord Injury
Interventions
Body composition
Other
Lead sponsor
Hunter Holmes Mcguire Veteran Affairs Medical Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 12, 2009 · Synced Oct 12, 2026, 3:50 PM EDT
Completed Phase 4 Interventional

The Effects of Aripiprazole on Patients With Metabolic Syndrome

NCT00224822
View directory record Official record
Conditions
Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Metabolic Syndrome X
Interventions
Aripiprazole
Drug
Lead sponsor
New Mexico VA Healthcare System
Federal
Eligibility
18 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Mar 24, 2010 · Synced Oct 12, 2026, 3:50 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effects of Brisk Walking and Regular Intensity Exercise Interventions on Glycemic Control

NCT03227575
View directory record Official record
Conditions
Metabolic Syndrome, Obesity
Interventions
Exercise Intervention
Behavioral
Lead sponsor
Plymouth State University
Other
Eligibility
18 Years to 39 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
2
States / cities
Plymouth, New Hampshire
Source: ClinicalTrials.gov public record
Updated Nov 12, 2024 · Synced Oct 12, 2026, 3:50 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Exenatide and Metformin Therapy in Overweight Women With PCOS

NCT00344851
View directory record Official record
Conditions
Polycystic Ovary Syndrome
Interventions
metformin, exenatide or combined (metformin & exenatide )
Drug
Lead sponsor
Metabolic Center of Louisiana Research Foundation
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jul 11, 2007 · Synced Oct 12, 2026, 3:50 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Group Lifestyle Balance DVD in Primary Care Practice

NCT00480779
View directory record Official record
Conditions
Prediabetes, Metabolic Syndrome
Interventions
GLB Group, GLB DVD
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 28, 2016 · Synced Oct 12, 2026, 3:50 PM EDT
Completed Phase 4 Interventional

Comparative Effects of Chronic Treatment With Olanzapine and Risperidone on Glucose and Lipid Metabolism

NCT00287820
View directory record Official record
Conditions
Schizophrenia, Diabetes, Metabolic Syndrome, Hyperglycemia
Interventions
olanzapine, risperidone
Drug
Lead sponsor
Nathan Kline Institute for Psychiatric Research
Other
Eligibility
18 Years to 65 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 25, 2011 · Synced Oct 12, 2026, 3:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Vestibular Stimulation on Fat Consumption and Energy Expenditure as Assessed Using Indirect Calorimetry

NCT03138382
View directory record Official record
Conditions
Obesity, Metabolic Syndrome
Interventions
Vestibular Nerve Stimulator, Sham stimulator
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jun 27, 2019 · Synced Oct 12, 2026, 3:50 PM EDT
Completed Not applicable Interventional Results available

Sleep Chatbot Intervention for Emerging Black/African American Adults

NCT05956886
View directory record Official record
Conditions
Sleep Deprivation, Insomnia, Metabolic Syndrome
Interventions
sleep chatbot
Behavioral
Lead sponsor
University of Delaware
Other
Eligibility
18 Years to 25 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Jul 31, 2026 · Synced Oct 12, 2026, 3:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Controlled Clinical Study to Determine Novel Health Benefits of Cheese Consumption

NCT02918422
View directory record Official record
Conditions
Metabolic Syndrome X
Interventions
Nutritional and Dietary Manipulation
Other
Lead sponsor
Ohio State University
Other
Eligibility
21 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 12, 2026, 3:50 PM EDT
Completed Phase 2 Interventional

Evaluation of Lifestyle Interventions to Treat Elevated Cardiometabolic Risk in Primary Care

NCT00842426
View directory record Official record
Conditions
Obesity, Pre-diabetes, Metabolic Syndrome
Interventions
Self-management program (SM), Care management program (CM)
Behavioral
Lead sponsor
Palo Alto Medical Foundation
Other
Eligibility
18 Years and older
Enrollment
241 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 13, 2012 · Synced Oct 12, 2026, 3:50 PM EDT
Terminated No phase listed Observational

Risks for Insulin Resistance and Metabolic Syndrome Between Major Depressive Disorder (MDD) or MDD With Psychotic Features

NCT01310140
View directory record Official record
Conditions
Major Depressive Disorder, Major Depressive Disorder w/ Psychotic Features, Metabolic Syndrome
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 13, 2017 · Synced Oct 12, 2026, 3:50 PM EDT
Recruiting Not applicable Interventional

The Effects of Cognitive Behavioral Therapy on Insulin Resistance in People With HIV

NCT07226128
View directory record Official record
Conditions
HIV, Depression in Adults, Insulin Resistance, Cognitive Behavior Therapy
Interventions
Internet cognitive behavioral therapy (iCBT-D), Active Control (AC)
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 12, 2026, 3:50 PM EDT
Active, not recruiting Not applicable Interventional

Telenutrition for Individuals With SCI

NCT05468437
View directory record Official record
Conditions
Spinal Cord Injuries, Obesity, Cardiometabolic Syndrome
Interventions
Telenutrition
Behavioral
Lead sponsor
Santa Clara Valley Health & Hospital System
Other
Eligibility
20 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 12, 2026, 3:50 PM EDT
Completed Not applicable Interventional

Diet and Depression

NCT06252701
View directory record Official record
Conditions
Depression, Major Depressive Disorder, Weight Gain, Obesity, Metabolic Syndrome
Interventions
Reduction of Ultra-processed foods
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 21, 2025 · Synced Oct 12, 2026, 3:50 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Combination Metformin and Oral Contraception for Polycystic Ovary Syndrome (PCOS)

NCT00682890
View directory record Official record
Conditions
Polycystic Ovary Syndrome, PCOS, Insulin Sensitivity
Interventions
placebo, metformin
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2010
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 20, 2014 · Synced Oct 12, 2026, 3:50 PM EDT