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ClinicalTrials.gov public records Last synced Sep 9, 2026, 3:15 AM EDT

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Showing 1–24 of 485 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Intensive Care Units Clear all
Recruiting Phase 2 Interventional

Subanesthetic Ketamine Infusions for Depressive Symptoms in Intensive Care Unit Patients

NCT07639359
View directory record Official record
Conditions
Critical Illness, Depressive Symptoms
Interventions
Ketamine (0.5 mg/kg), Normal Saline (0.9% NaCl)
Drug · Other
Lead sponsor
Hospital Italiano de Buenos Aires
Other
Eligibility
18 Years to 99 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 9, 2026, 3:15 AM EDT
Completed Not applicable Interventional Results available

Duration of Antibiotic Treatment for Early VAP (DATE) Trial

NCT01994980
View directory record Official record
Conditions
Early Ventilator Associated Pneumonia
Interventions
Default 4 days antibiotic therapy
Drug
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 9, 2023 · Synced Sep 9, 2026, 3:15 AM EDT
Completed Not applicable Interventional Results available

Use of Neuromuscular Electrostimulation (NMES) for Treatment or Prevention of ICU-Associated Weakness

NCT00709124
View directory record Official record
Conditions
Intensive Care Unit, Muscle Weakness
Interventions
Neuromuscular Electrostimulation (NMES) CareStim Muscle Stimulation Device (Care Rehab; McLean, VA), Sham
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 22, 2018 · Synced Sep 9, 2026, 3:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Decreasing Catheter-Associated Urinary Tract Infections in the Pediatric Intensive Care Unit

NCT00672503
View directory record Official record
Conditions
Urinary Tract Infections
Interventions
Not listed
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
1 Day to 17 Years
Enrollment
321 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 11, 2011 · Synced Sep 9, 2026, 3:15 AM EDT
Recruiting Not applicable Interventional

Echography-guided Surfactant THERapy (ESTHER) For Preterm Infants With Respiratory Failure

NCT06446453
View directory record Official record
Conditions
Respiratory Distress Syndrome, Newborn, Pulmonary Surfactants, Intensive Care Units, Neonatal
Interventions
Echography-guided Surfactant THERapy (ESTHER)
Diagnostic Test
Lead sponsor
Connecticut Children's Medical Center
Other
Eligibility
0 Hours to 2 Hours
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Sep 9, 2026, 3:15 AM EDT
Completed Not applicable Interventional Results available

Feasibility, Acceptability, and Barriers to Implementation of a Geriatrics Bundle in the ICU

NCT04652453
View directory record Official record
Conditions
Intensive Care Unit Syndrome
Interventions
Geriatrics Bundle
Other
Lead sponsor
Yale University
Other
Eligibility
65 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 15, 2024 · Synced Sep 9, 2026, 3:15 AM EDT
Completed Phase 4 Interventional Results available

Intravenous Exenatide in Coronary Intensive Care Unit (ICU) Patients

NCT00736229
View directory record Official record
Conditions
Hyperglycemia, Acute Coronary Syndromes, Myocardial Infarction
Interventions
Exenatide
Drug
Lead sponsor
Saint Luke's Health System
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 19, 2014 · Synced Sep 9, 2026, 3:15 AM EDT
Completed Not applicable Interventional

Intermittent Versus Continuous Enteral Nutrition in Mechanically Ventilated Patients in the Medical Intensive Care Unit

NCT04437264
View directory record Official record
Conditions
Enteral Feeding, Nutrition Disorders
Interventions
Intermittent feed participant, Continuous feeds participant
Dietary Supplement
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 2, 2025 · Synced Sep 9, 2026, 3:15 AM EDT
Completed No phase listed Observational

Pharmacist-Driven Stress Ulcer Prophylaxis Minimization in the Intensive Care Unit

NCT06225167
View directory record Official record
Conditions
Stress Ulcer
Interventions
To evaluate the effectiveness and safety of a pharmacist-driven protocol to discontinue stress ulcer prophylaxis in ICU patients when it is no longer indicated according to pre-defined criteria.
Behavioral
Lead sponsor
Methodist Health System
Other
Eligibility
18 Years to 85 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Sep 9, 2026, 3:15 AM EDT
Enrolling by invitation Not applicable Interventional

Impact of Intensive Care Unit Nurse Participation in Post - ICU Follow Up Clinic

NCT04243356
View directory record Official record
Conditions
Nurse-Patient Relations, Nurse Role
Interventions
Nurse Encounter Group, Nurse control group
Behavioral · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 9, 2026, 3:15 AM EDT
Not listed Not applicable Interventional

Comparison of Breastfeeding Teaching Intervention

NCT03602729
View directory record Official record
Conditions
Breast Feeding
Interventions
Breastfeeding education
Other
Lead sponsor
Brookdale University Hospital Medical Center
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Jan 17, 2019 · Synced Sep 9, 2026, 3:15 AM EDT
Recruiting Not applicable Interventional

Neurosteer Bedside Monitoring System

NCT06718764
View directory record Official record
Conditions
Delirium, Sedation, Agitation
Interventions
Neurosteer's single-channel EEG monitoring device
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Sep 9, 2026, 3:15 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Study of Bathing With Chlorhexidine Impregnated Cloths on Nosocomial Infections in the Pediatric Intensive Care Unit

NCT00549393
View directory record Official record
Conditions
Nosocomial Infections
Interventions
2% Chlorhexidine gluconate cloth
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
2 Months to 25 Years
Enrollment
5,659 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
5
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 13, 2017 · Synced Sep 9, 2026, 3:15 AM EDT
Completed No phase listed Observational

Helping Older Persons Emerge Stronger

NCT02863081
View directory record Official record
Conditions
Delirium, Ventilators, Pain, Agitation, Anxiety
Interventions
Survey, interview
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 18, 2017 · Synced Sep 9, 2026, 3:15 AM EDT
Completed Not applicable Interventional Results available

Improving Family Meetings in the Pediatric Cardiac Intensive Care Unit

NCT03749330
View directory record Official record
Conditions
Communication, Critical Illness
Interventions
CICU Team And Loved Ones Communicating (CICU TALC)
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Not listed
Enrollment
451 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 17, 2024 · Synced Sep 9, 2026, 3:15 AM EDT
Completed Not applicable Interventional

Assessing the Impact of LIve Music in the Intensive Care Unit (ICU) to Improve Care for Critically Ill Patients

NCT03948984
View directory record Official record
Conditions
Anxiety, Pain, Critical Illness, Relaxation
Interventions
Therapeutic Music Session
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Sep 9, 2026, 3:15 AM EDT
Terminated Not applicable Interventional Results available

Use of Dexmedetomidine to Facilitate Extubation in Surgical ICU Patients Who Failed Previous Weaning Attempts

NCT00464490
View directory record Official record
Conditions
Intubation; Difficult, Respiration Disorders
Interventions
Dexmedetomidine
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 69 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 30, 2014 · Synced Sep 9, 2026, 3:15 AM EDT
Terminated Not applicable Interventional

Effect and Utilization of Protected Time Among Interns on Extended Duty-Hour Call Shifts

NCT00983008
View directory record Official record
Conditions
Fatigue, Sleep Deprivation, Depression
Interventions
Protected time and Dedicated time
Behavioral
Lead sponsor
Providence Health & Services
Other
Eligibility
Not listed
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 25, 2019 · Synced Sep 9, 2026, 3:15 AM EDT
Completed Not applicable Interventional Results available

Rapid Identification and Phenotypic Susceptibility Testing for Gram-Negative Bacteremia

NCT03218397
View directory record Official record
Conditions
Gram-negative Bacteremia
Interventions
Accelerate PhenoTest™ BC Kit, Standard Culture and AST
Device
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Los Angeles, California • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 25, 2019 · Synced Sep 9, 2026, 3:15 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Role of Transposable Elements in Septic Immune Aging

NCT06809868
View directory record Official record
Conditions
Sepsis, Sepsis and Septic Shock, Sepsis With Multiple Organ Dysfunction (MOD), Sepsis With Acute Organ Dysfunction, Sepsis, Severe, Sepsis at Intensive Care Unit, Sepsis, Severe Sepsis and Septic Shock, Sepsis, Septic Shock
Interventions
RNA and DNA Sequencing
Genetic
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Sep 9, 2026, 3:15 AM EDT
Not yet recruiting Not applicable Interventional

Randomized Evaluation of Operating Room Extubation After Cardiac Surgery

NCT07757880
View directory record Official record
Conditions
Cardiac Surgery
Interventions
OR extubation, ICU extubation
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 9, 2026, 3:15 AM EDT
Terminated No phase listed Observational

Detection of Gastrointestinal Bleeding in Intensive Care Patients Via Biosensor Watch

NCT03874169
View directory record Official record
Conditions
Gastro Intestinal Bleeding
Interventions
E4 wristband
Device
Lead sponsor
Columbia University
Other
Eligibility
25 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 2, 2023 · Synced Sep 9, 2026, 3:15 AM EDT
Completed Not applicable Interventional Results available

Mobile Mindfulness to Improve Psychological Distress After Critical Illness

NCT02701361
View directory record Official record
Conditions
Psychological Distress, Depression, Anxiety, Post-traumatic Stress Disorder, Informal Caregivers, Family Members
Interventions
mobile mindfulness, standard mindfulness, education
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Durham, North Carolina • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 6, 2018 · Synced Sep 9, 2026, 3:15 AM EDT
Completed No phase listed Observational

Critical Care Observation of Motor Activity (COMA) and SICU Outcomes

NCT02994641
View directory record Official record
Conditions
Motor Activity, Muscle Strength, Muscle Weakness
Interventions
COMA Score Assessment
Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 112 Years
Enrollment
761 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 15, 2016 · Synced Sep 9, 2026, 3:15 AM EDT