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Showing 1–24 of 27 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional Results available

NHLBI DIR LAMPOON Study: Intentional Laceration of the Anterior Mitral Leaflet to Prevent Left Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Implantation

NCT03015194
View directory record Official record
Conditions
Mitral Valve Failure
Interventions
Edwards SAPIEN 3 transcatheter heart valve, ASHI INTECC Astato XS 20
Device
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
21 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
6
States / cities
Washington D.C., District of Columbia • Atlanta, Georgia • Detroit, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Sep 5, 2026, 4:28 PM EDT
Completed Not applicable Interventional

Aesthetic Outcome of Complex Linear Closure vs Second Intention Healing: Below the Knee

NCT05074212
View directory record Official record
Conditions
Wound Heal, Wound of Skin
Interventions
Factorial Assignment
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Sep 5, 2026, 4:28 PM EDT
Not yet recruiting Not applicable Interventional

Enhancing an Existing Prevention Strategy to Reduce Intentional Firearm Injuries Among High-risk Youth (Phase 1)

NCT07305467
View directory record Official record
Conditions
Prevention
Interventions
Establish an advisory board of high-risk youth, Feedback and advice sessions, Youth advisory board training, Semi-structured focus groups
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
13 Years to 17 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 5, 2026, 4:28 PM EDT
Completed Not applicable Interventional Results available

Wet-to-dry vs Petrolatum & Non-stick Dressings After Hidradenitis Suppurativa Surgery

NCT05194969
View directory record Official record
Conditions
Hidradenitis Suppurativa, Surgical Wound
Interventions
Wet-to-Dry Dressings, Petrolatum with Non-Stick Gauze
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
16 Years to 99 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 17, 2025 · Synced Sep 5, 2026, 4:28 PM EDT
Completed Not applicable Interventional Results available

Enhanced Secondary Intention Healing vs. Standard Secondary Intention Healing in Mohs Surgical Defects on the Head and Distal Lower Extremities

NCT04545476
View directory record Official record
Conditions
Wound Heal
Interventions
Participants in this group will receive the experimental APIS Biomaterial on the Head., Participants in this group will receive the experimental APIS Biomaterial on the Lower Extremities., Standard Secondary Intention Healing on the Head, Standard Secondary Intention Healing on the Lower Extremities
Device · Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 11, 2023 · Synced Sep 5, 2026, 4:28 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Ultrasound Imaging Based Sensing of Human Ankle Motion Intent and Control Strategies for Ankle Assistance

NCT05249595
View directory record Official record
Conditions
Incomplete Spinal Cord Injury, Transverse Myelitis
Interventions
Surface electromypgraphy-based interface to predict human ankle joint motion intent and use in ankle assistive devices, Ultrasound imaging-based interface to predict human ankle joint motion intent and use in ankle assistive devices, Surface electromypgraphy and ultrasound imaging-based interface to predict human ankle joint motion intent and use in ankle assistive devices
Device
Lead sponsor
North Carolina State University
Other
Eligibility
18 Years to 64 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 20, 2022 · Synced Sep 5, 2026, 4:28 PM EDT
Terminated Not applicable Interventional Results available

Porcine Xenograft Versus Second Intention Healing

NCT03931746
View directory record Official record
Conditions
Wound Healing and Scar Quality Following Mohs Surgery and Excisional Dermatologic Surgery
Interventions
Porcine xenograft
Device
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Bay Shore, New York • Lake Success, New York
Source: ClinicalTrials.gov public record
Updated Mar 19, 2023 · Synced Sep 5, 2026, 4:28 PM EDT
Recruiting Not applicable Interventional

Pinch Grafting Versus Second Intention Wound Healing for Mohs Micrographic Surgery Defects on the Scalp

NCT06287866
View directory record Official record
Conditions
Scarring
Interventions
Pinch Graft
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Sep 5, 2026, 4:28 PM EDT
Completed Not applicable Interventional

At-risk Intervention and Mentoring Evaluation

NCT02174224
View directory record Official record
Conditions
Violence
Interventions
Brief Intervention, Case Management, Standard Medical Care
Behavioral
Lead sponsor
Denver Health and Hospital Authority
Other
Eligibility
14 Years to 24 Years
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 10, 2021 · Synced Sep 5, 2026, 4:28 PM EDT
Recruiting Phase 3 Interventional

The Effect of Bacterial Decolonization Before Skin Cancer Surgery on Infection Rate of Lower Extremity Wounds Left Open to Heal

NCT07142408
View directory record Official record
Conditions
Surgical Wound Infection
Interventions
Chlorhexidine gluconate (4%), Mupirocin 2% Ointment
Drug
Lead sponsor
The Cooper Health System
Other
Eligibility
18 Years and older
Enrollment
848 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
1
States / cities
Marlton, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Sep 5, 2026, 4:28 PM EDT
Completed Not applicable Interventional Results available

Bioprosthetic or Native Aortic Scallop Intentional Laceration to Prevent Iatrogenic Coronary Artery Obstruction (BASILICA) Prospective Investigation

NCT03381989
View directory record Official record
Conditions
Native and Valve in Valve Aortic Valve Failure
Interventions
ASHI_INTECC Astato XS 20 0.014 guidewire
Device
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
21 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
4
States / cities
Washington D.C., District of Columbia • Atlanta, Georgia • Detroit, Michigan + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 17, 2021 · Synced Sep 5, 2026, 4:28 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

HISTOACRYL: A Study of Its Efficacy in Final Scar Formation

NCT00890578
View directory record Official record
Conditions
Surgical Incisions
Interventions
adhesive to suture
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
21 Years and older · Female only
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 20, 2012 · Synced Sep 5, 2026, 4:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Concussion Education Programs

NCT04492696
View directory record Official record
Conditions
Concussion, Brain
Interventions
Education
Other
Lead sponsor
Stanford University
Other
Eligibility
14 Years to 19 Years · Male only
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jul 29, 2020 · Synced Sep 5, 2026, 4:28 PM EDT
Terminated Not applicable Interventional Results available

Doubleblinded RCT of the Omnilux on Lower Extremity Surgical Wounds Left to Heal by Second Intention

NCT02383056
View directory record Official record
Conditions
Wound
Interventions
Omnilux, Omnilux Sham
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 90 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 22, 2019 · Synced Sep 5, 2026, 4:28 PM EDT
Completed Not applicable Interventional

Evaluation of Purse-String Closure Vs Second Intention

NCT02062866
View directory record Official record
Conditions
Wound Closure Techniques
Interventions
Purse-String, Second Intent
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 15, 2015 · Synced Sep 5, 2026, 4:28 PM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Ostomy Primary Closure With 0.1% Betaine/Polyhexanide Wound Irrigation Compared to Pursestring Closure

NCT06309368
View directory record Official record
Conditions
Surgical Site Infection, Wound Surgical, Colorectal Disorders
Interventions
Primary Ostomy Closure with 0.1% Betaine/0.1% Polyhexanide Wound Irrigation, Pursestring Closure
Drug · Procedure
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Jun 1, 2025 · Synced Sep 5, 2026, 4:28 PM EDT
Not listed Phase 4 Interventional

Pilonidal Disease Wound Healing Study

NCT01857128
View directory record Official record
Conditions
Pilonidal Disease
Interventions
Drawtex dressing, Negative Pressure Wound Therapy
Device
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 19, 2013 · Synced Sep 5, 2026, 4:28 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Addressing Attitudes to Improve Use of Protective Headwear in Older Adults

NCT01582464
View directory record Official record
Conditions
Injury of Unknown Intent Due to Fall From Height, Traumatic Brain Injury
Interventions
Social Marketing for protective headgear
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
65 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Multiple, California
Source: ClinicalTrials.gov public record
Updated May 8, 2016 · Synced Sep 5, 2026, 4:28 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Platelets for Acute Wound Healing

NCT00125086
View directory record Official record
Conditions
Wounds
Interventions
autologous platelet gel
Device
Lead sponsor
Medtronic
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 13, 2005 · Synced Sep 5, 2026, 4:28 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Feasibility of Virtual Tai Chi Easy for Registered Nurses

NCT06423638
View directory record Official record
Conditions
Transition Shock, Nurses' Intention to Quit, Stress, Somatic Symptoms, Burnout, Trauma and Stressor Related Disorders
Interventions
Virtual Tai Chi Easy
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 99 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Sep 5, 2026, 4:28 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Healthy Relationships and Economic Pathways

NCT03519191
View directory record Official record
Conditions
Adolescent Relationship Abuse, Sexually Transmitted Infections, Pregnancy (Unwanted), Violence, Intentional Injury
Interventions
Healthy Relationships Education (HRE), HRE+Technology Bootcamp
Behavioral
Lead sponsor
Public Health Institute, California
Other
Eligibility
18 Years to 24 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Sep 12, 2019 · Synced Sep 5, 2026, 4:28 PM EDT
Terminated No phase listed Observational

PMCF Study to Evaluate the VERTICALE® Cervical System in Spine Surgery According to Its Intended Use.

NCT05489822
View directory record Official record
Conditions
Degenerative Disc Disease (DDD), Instabilities, Trauma, Deformity
Interventions
VERTICALE® Cervical System
Device
Lead sponsor
Silony Medical GmbH
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Sep 5, 2026, 4:28 PM EDT
Terminated Not applicable Interventional Results available

Secondary Intention Wound Healing Versus Micrografting in Patients Undergoing Mohs Surgery

NCT01442844
View directory record Official record
Conditions
Impaired Wound Healing
Interventions
Micrografting
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
40 Years to 75 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 16, 2014 · Synced Sep 5, 2026, 4:28 PM EDT
Recruiting Not applicable Interventional

Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT)

NCT07521930
View directory record Official record
Conditions
Tetraplegia/Tetraparesis, Amyotrophic Lateral Sclerosis (ALS), Muscular Disorders, Atrophic, Brain Stem Stroke, Spinal Cord Injuries (SCI), Muscular Dystrophies, Muscular Atrophy, Progressive, Pontine Hemorrhage, Pontine Infarction
Interventions
INTENT Neural Interface System
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 5, 2026, 4:28 PM EDT