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ClinicalTrials.gov public records Last synced Oct 27, 2026, 1:08 PM EDT

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Showing 649–672 of 680 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Intestinal Microbiome Clear all
Not listed No phase listed Observational

Predicting Chronic Opioid Use Following Lower Extremity Joint Arthroplasty

NCT04974463
View directory record Official record
Conditions
Joint Pain, Chronic Pain, Opioid Use
Interventions
Not listed
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 27, 2026, 1:08 PM EDT
Completed No phase listed Observational

Endotoxin and Intestinal Flora Before and After Gastric Bypass or Banding in Diabetics

NCT00960765
View directory record Official record
Conditions
Obesity, Morbid, Diabetes Mellitus, Type 2, Gastric Bypass
Interventions
Not listed
Lead sponsor
CPL Associates
Other
Eligibility
18 Years to 95 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
2
States / cities
Buffalo, New York • Williamsville, New York
Source: ClinicalTrials.gov public record
Updated Jan 28, 2016 · Synced Oct 27, 2026, 1:08 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Early Iron Exposure on the Gut Microbiota in Young Infants

NCT03828708
View directory record Official record
Conditions
Infant Development
Interventions
Iron in infant formula
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
1 Day to 4 Months
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 2, 2023 · Synced Oct 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Gut Microbiota Changes in Obese Individuals Undergoing Dedicated Lifestyle Modification Programs

NCT02855242
View directory record Official record
Conditions
Obesity
Interventions
Lifestyle Counseling, Controls Group
Behavioral · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 16, 2021 · Synced Oct 27, 2026, 1:08 PM EDT
Recruiting No phase listed Observational

Impact of Gut Microbiome on Metabolic and Bowel Function During the First Year After Spinal Cord Injury

NCT05670288
View directory record Official record
Conditions
Spinal Cord Injuries, Gut Microbiome
Interventions
Not listed
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 85 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Oct 27, 2026, 1:08 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Low Sugar Protein Pacing, Intermittent Fasting Diet in Men and Women

NCT04327141
View directory record Official record
Conditions
Weight Loss, Gut Microbiome, Anti-Aging
Interventions
P-IF, HH
Behavioral
Lead sponsor
Skidmore College
Other
Eligibility
25 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Saratoga Springs, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2024 · Synced Oct 27, 2026, 1:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Almonds, Gut Microbiome and Kids

NCT07636850
View directory record Official record
Conditions
Dysbiosis, Cardiometabolic Health Indicators
Interventions
Creamy Richards 100% Almonds! Creamy Natural Almond Butter, Cadbury Milk Chocolate Spread
Other
Lead sponsor
Florida State University
Other
Eligibility
6 Years to 13 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 27, 2026, 1:08 PM EDT
Active, not recruiting Not applicable Interventional

Can Gut Bacteria Predict Who Benefits Most From Exercise? A Gut Supplement to Help Exercise Non-Responders

NCT07180446
View directory record Official record
Conditions
Obesity &Amp; Overweight
Interventions
Cardiovascular Exercise, Butyrate
Behavioral · Dietary Supplement
Lead sponsor
Texas Christian University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 27, 2026, 1:08 PM EDT
Recruiting No phase listed Observational

The Gut Microbiome and Serum Metabolites as a Biological Mechanism Underlying Pain in Kidney Transplantation

NCT06206486
View directory record Official record
Conditions
Kidney Transplant Symptoms, Gut Microbiome
Interventions
no intervention, observational
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years and older
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 27, 2026, 1:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Native Chicory Inulin on Change and Persistence of Gut Microbiota

NCT06528041
View directory record Official record
Conditions
Healthy
Interventions
Inulin, Maltodextrin
Other
Lead sponsor
Purdue University
Other
Eligibility
18 Years to 45 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Oct 27, 2026, 1:08 PM EDT
Completed Phase 1 Interventional

Vitamin D Regulation of Gut Specific B Cells and Antibodies Targeting Gut Bacteria in Inflammatory Bowel Disease

NCT04828031
View directory record Official record
Conditions
Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
Interventions
Vitamin D
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 21, 2023 · Synced Oct 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Consuming Red Meat on the Gut Microbiota in Young Adults

NCT03885544
View directory record Official record
Conditions
Diet Modification
Interventions
Controlled Lacto-ovo vegetarian diet, Controlled Unprocessed red meat diet, Controlled processed red meat diet
Other
Lead sponsor
Purdue University
Other
Eligibility
20 Years to 35 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Jul 14, 2020 · Synced Oct 27, 2026, 1:08 PM EDT
Completed Phase 2 Interventional Results available

MTT for Children With Both Pitt Hopkins Syndrome and Gastrointestinal Disorders

NCT04132427
View directory record Official record
Conditions
Pitt Hopkins Syndrome
Interventions
vancomycin, magnesium citrate, microbiota, placebo vancomycin, real magnesium citrate, placebo microbiota
Combination Product
Lead sponsor
Arizona State University
Other
Eligibility
7 Years to 17 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 26, 2024 · Synced Oct 27, 2026, 1:08 PM EDT
Active, not recruiting No phase listed Observational

Hypoglycemia and the Gut Microbiome

NCT03385707
View directory record Official record
Conditions
Hypoglycemia
Interventions
Not listed
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 6, 2026 · Synced Oct 27, 2026, 1:08 PM EDT
Recruiting Not applicable Interventional

A Pilot Study Examining Low Sulfur Diet as Treatment for Persistent Symptoms in Quiescent Crohn's Disease

NCT05849012
View directory record Official record
Conditions
Crohn's Disease in Remission
Interventions
Low Sulfur Diet, Usual Diet
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Oct 27, 2026, 1:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Assessing the Short-Term Effects of Multi-Fiber Supplementation on Gut Health

NCT07787026
View directory record Official record
Conditions
Mixed Fiber Supplementation for Healthy Adults
Interventions
Prebiotic, Placebo
Dietary Supplement
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 26, 2026 · Synced Oct 27, 2026, 1:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Gut Microbiota Composition in Hispanic and Non-Hispanic Children.

NCT03990350
View directory record Official record
Conditions
Obesity
Interventions
Fecal Sample Collection, Physical Activity Questionnaire, Food Frequency Questionnaire, 24-hour dietary recall diary
Other
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
6 Years to 12 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jun 30, 2020 · Synced Oct 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Dietary Sodium Supplementation on Growth & Intestinal Microbiome

NCT05546814
View directory record Official record
Conditions
Preterm Birth
Interventions
Sodium algorithm
Procedure
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
25 Weeks to 30 Weeks
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Oct 27, 2026, 1:08 PM EDT
Recruiting Phase 1 Interventional

Vancomycin Study in Multiple Sclerosis (MS)

NCT05539729
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Vancomycin, Placebo
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 50 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 27, 2026, 1:08 PM EDT
Recruiting Not applicable Interventional

BILe Acid-gut Microbiome Axis MODification Through Diet Education for Colorectal Cancer Prevention

NCT07162337
View directory record Official record
Conditions
Colorectal Cancer Prevention, Colorectal Adenoma
Interventions
Increased Plant-Based Diet and Decreased Animal-Based Diet
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Oct 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional

Elemental Diet and Gut Microbiome

NCT05978973
View directory record Official record
Conditions
Irritable Bowel Syndrome
Interventions
Elemental Diet
Dietary Supplement
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Oct 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intermediate Wheatgrass Products and Gut Health

NCT07773441
View directory record Official record
Conditions
Gut Health, Gastrointestinal Symptoms, Gut Microbiome, Dietary Fiber
Interventions
Intermediate Wheatgrass-Based Products, Whole Wheat-Based Products
Dietary Supplement
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 15, 2026 · Synced Oct 27, 2026, 1:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Role of Dietary Intake and Host Genetics in Gut Microbiome Response to Resistant Starch Consumption

NCT05743790
View directory record Official record
Conditions
Healthy Volunteers
Interventions
RS2-control-RS4, RS4-control-RS2
Dietary Supplement
Lead sponsor
Cornell University
Other
Eligibility
18 Years and older
Enrollment
196 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Ithaca, New York
Source: ClinicalTrials.gov public record
Updated Apr 3, 2023 · Synced Oct 27, 2026, 1:08 PM EDT
Terminated Not applicable Interventional Results available

Gut Microbiome & Gastrointestinal Toxicities as Determinants of Response to Neoadjuvant Chemo for Advanced Breast Cancer

NCT02696759
View directory record Official record
Conditions
Breast Cancer
Interventions
Blood & Fecal Collection
Other
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Mar 16, 2022 · Synced Oct 27, 2026, 1:08 PM EDT