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ClinicalTrials.gov public records Last synced Oct 24, 2026, 1:34 AM EDT

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Showing 145–168 of 680 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Intestinal Microbiome Clear all
Completed Not applicable Interventional Accepts healthy volunteers

To Investigate the Effect of Arabinogalactan on the Gut Microbiome in Adults

NCT04351841
View directory record Official record
Conditions
Gut Microbiota
Interventions
arabinogalactan, maltodextrin
Other
Lead sponsor
Biofortis, Merieux NutriSciences
Industry
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Addison, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 22, 2020 · Synced Oct 24, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Salty Gut: Effects of High Dietary Salt Intake on the Gut Microbiota

NCT04229680
View directory record Official record
Conditions
Cardiovascular Risk Factor
Interventions
High Salt, Recommended Salt
Other
Lead sponsor
University of Delaware
Other
Eligibility
18 Years to 45 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Oct 2, 2023 · Synced Oct 24, 2026, 1:34 AM EDT
Not listed No phase listed Observational

Predicting Chronic Opioid Use Following Lower Extremity Joint Arthroplasty

NCT04974463
View directory record Official record
Conditions
Joint Pain, Chronic Pain, Opioid Use
Interventions
Not listed
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 24, 2026, 1:34 AM EDT
Active, not recruiting Not applicable Interventional

A Culturally Tailored Dietary Intervention to Treat Crohn's Disease

NCT05627128
View directory record Official record
Conditions
Crohn Disease
Interventions
DAIN
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
21 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 24, 2026, 1:34 AM EDT
Active, not recruiting Early Phase 1 Interventional Accepts healthy volunteers

Analysis of the Microbiome in Rosacea

NCT04108897
View directory record Official record
Conditions
Rosacea
Interventions
Doxycycline, Ivermectin Topical
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 99 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 24, 2026, 1:34 AM EDT
Withdrawn No phase listed Observational

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Ulcerative Colitis

NCT04148274
View directory record Official record
Conditions
Ulcerative Colitis, Ulcerative Colitis Chronic
Interventions
No intervention
Other
Lead sponsor
ProgenaBiome
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2030
U.S. locations
1
States / cities
Ventura, California
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Oct 24, 2026, 1:34 AM EDT
Terminated No phase listed Observational

Gut and Tumor Microbiome in Patients With Early Stage (II-III), Locally Advanced or Advanced ER-positive and HER2-negative Breast Cancer.

NCT06126003
View directory record Official record
Conditions
Breast Cancer
Interventions
Observation
Other
Lead sponsor
BioCorteX Inc
Industry
Eligibility
18 Years to 85 Years · Female only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
6
States / cities
Decatur, Illinois • Las Vegas, Nevada • Belleville, New Jersey + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2024 · Synced Oct 24, 2026, 1:34 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Alteration of Stool Microbiota in Preterm Infants With Anemia

NCT03554278
View directory record Official record
Conditions
Anemia, Neonatal, Necrotizing Enterocolitis, Dysbiosis
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
7 Days to 30 Days
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Oct 24, 2026, 1:34 AM EDT
Withdrawn No phase listed Observational

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Anxiety

NCT04211376
View directory record Official record
Conditions
Anxiety, Anxiety Disorders, Anxiety Depression
Interventions
No Intervention
Other
Lead sponsor
ProgenaBiome
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2030
U.S. locations
1
States / cities
Ventura, California
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Oct 24, 2026, 1:34 AM EDT
Terminated Phase 2 Interventional

Investigational Microbiota Restoration Therapeutic for Hepatic Encephalopathy

NCT04155099
View directory record Official record
Conditions
Hepatic Encephalopathy, Cirrhosis, Liver
Interventions
RBX7455, Placebo
Biological
Lead sponsor
Ochsner Health System
Other
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Jefferson, Louisiana
Source: ClinicalTrials.gov public record
Updated Oct 3, 2023 · Synced Oct 24, 2026, 1:34 AM EDT
Completed Not applicable Interventional

Salmon Intake and Gut Health in Adults

NCT04792216
View directory record Official record
Conditions
Gut Microbiome, Inflammation
Interventions
Wild Salmon, Farmed Salmon
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
30 Years to 50 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 19, 2024 · Synced Oct 24, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Influence of Cannabidiol on Glucose Tolerance and The Gut Microbiota

NCT05285449
View directory record Official record
Conditions
Diabetes
Interventions
Cannabidiol (CBD) powder formulation, Matching Placebo Cannabidiol (CBD) powder formulation
Dietary Supplement
Lead sponsor
Christopher Bell
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 24, 2026, 1:34 AM EDT
Recruiting No phase listed Observational

Celiac Disease Genomic Environmental Microbiome and Metabolomic Study

NCT02061306
View directory record Official record
Conditions
Celiac Disease
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
Up to 6 Months
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 24, 2026, 1:34 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Impact of Soluble Arabinoxylan and Rice Bran Fiber on the Gut Microbiome in Healthy Adults

NCT06873204
View directory record Official record
Conditions
Healthy
Interventions
Soluble Arabinoxylan, Rice Bran, Maltodextrin (Placebo)
Dietary Supplement
Lead sponsor
Purdue University
Other
Eligibility
18 Years to 45 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 29, 2025 · Synced Oct 24, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Clinical Study to Assess the Effect of Novel Glycans on Nitrogen Metabolism of the Gut in Healthy Subjects

NCT04603378
View directory record Official record
Conditions
Healthy
Interventions
KB195, Polydextrose, Pullulan, Maltodextrin
Other
Lead sponsor
Kaleido Biosciences
Industry
Eligibility
18 Years to 50 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 26, 2020 · Synced Oct 24, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

DASH INtervention to INvestigate the Gut

NCT04538482
View directory record Official record
Conditions
Microbiota, Cancer
Interventions
DASH Diet, standard American diet
Behavioral
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
19 Years to 65 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 24, 2026, 1:34 AM EDT
Completed No phase listed Observational

Kids Intestinal Dysfunction in Congenital Heart Disease: the Kind Heart Study

NCT02824705
View directory record Official record
Conditions
Congenital Disease
Interventions
Congenital Heart Disease Surgery
Procedure
Lead sponsor
University of Arizona
Other
Eligibility
3 Days to 2 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Oct 24, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Time-Restricted Eating and Mindfulness-Based Stress Reduction to Reduce the Risk of Early-Onset Colorectal Cancer

NCT06022887
View directory record Official record
Conditions
Obesity, Colorectal Cancer, Microbial Colonization, Time Restricted Feeding, Stress, Psychological
Interventions
TRE, MBSR
Behavioral
Lead sponsor
Lisa Tussing-Humphreys
Other
Eligibility
18 Years to 39 Years
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Oct 24, 2026, 1:34 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Phage-based Control and Limitation of Pathobionts for Microbiome Equilibrium and Resilience

NCT07816809
View directory record Official record
Conditions
Gastrointestinal Symptoms, Skin Quality
Interventions
Bacteriophages - MuniPhage, Bacteriophages - RenuPhage, Placebo
Dietary Supplement · Other
Lead sponsor
Colorado State University
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 24, 2026, 1:34 AM EDT
Recruiting Phase 2 Interventional

The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action

NCT05414409
View directory record Official record
Conditions
Type 1 Diabetes, Obesity
Interventions
Metformin
Drug
Lead sponsor
Heba M. Ismail
Other
Eligibility
11 Years to 18 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 21, 2026 · Synced Oct 24, 2026, 1:34 AM EDT
Completed Phase 1Phase 2 Interventional

FMT in Pediatric Crohn's Disease

NCT03194529
View directory record Official record
Conditions
Crohn Disease, Pediatric Crohns Disease
Interventions
FMT
Biological
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
7 Years to 21 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 13, 2020 · Synced Oct 24, 2026, 1:34 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Gut Mini-Pill Study

NCT07220369
View directory record Official record
Conditions
Gut Microbiota
Interventions
plant-based meat alternative entrees, mini-pill, meat based entree
Other · Device
Lead sponsor
Tufts University
Other
Eligibility
50 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Oct 24, 2026, 1:34 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Changes in Vaginal, Cervical and Uterine Microflora With Levonorgestrel Intrauterine Device Placement

NCT01496898
View directory record Official record
Conditions
Human Microbiome, Metagenome, Contraception, Cytokine
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 13, 2016 · Synced Oct 24, 2026, 1:34 AM EDT
Completed No phase listed Observational

Microbes and Bariatric Surgery

NCT01130207
View directory record Official record
Conditions
Obesity, Diabetes, Periodontal Disease
Interventions
Not listed
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years to 65 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Nov 19, 2014 · Synced Oct 24, 2026, 1:34 AM EDT