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ClinicalTrials.gov public records Last synced Oct 26, 2026, 4:54 AM EDT

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Showing 25–48 of 126 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Intestinal Obstruction Clear all
Completed Phase 1Phase 2 Interventional

Endoscopic Placement of Metal Stent in Patients With Cancer-Related Bowel Obstruction

NCT00004911
View directory record Official record
Conditions
Colorectal Cancer, Constipation, Impaction, and Bowel Obstruction, Gastric Cancer, Gastrointestinal Carcinoid Tumor, Gastrointestinal Stromal Tumor, Quality of Life, Small Intestine Cancer
Interventions
bowel obstruction management, quality-of-life assessment
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2003
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 6, 2012 · Synced Oct 26, 2026, 4:54 AM EDT
Not listed Phase 4 Interventional

Neostigmine Route for Acute Colonic Pseudo Obstruction

NCT04951726
View directory record Official record
Conditions
Ogilvie Syndrome
Interventions
Neostigmine
Drug
Lead sponsor
University of Southern California
Other
Eligibility
16 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 25, 2023 · Synced Oct 26, 2026, 4:54 AM EDT
Withdrawn Not applicable Interventional

AspireAssist for Palliative Venting Gastrostomy in Malignant Bowel Obstruction Patients

NCT04375462
View directory record Official record
Conditions
Malignant Small Bowel Obstruction, Malignant Gastric Outlet Obstruction
Interventions
AspireAssist device, Standard decompressive PEG tube, gastric outlet obstruction scoring system (GOOSS) questionnaire, Modified Gastroparesis Cardinal Symptom Index (GCSI) questionnaire, Patient satisfaction and ease of use survey
Device · Other
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 31, 2023 · Synced Oct 26, 2026, 4:54 AM EDT
Completed Phase 2 Interventional Results available

Subcutaneous Methylnaltrexone Versus Placebo for Postoperative Ileus Prevention

NCT03852524
View directory record Official record
Conditions
Postoperative Ileus
Interventions
Methylnaltrexone, Placebo
Drug · Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 27, 2021 · Synced Oct 26, 2026, 4:54 AM EDT
Terminated Not applicable Interventional

Roux-en-Y Gastric Bypass Versus Loop Gastrojejunostomy for Malignant Gastric Outlet Obstruction

NCT05986890
View directory record Official record
Conditions
Malignant Gastric Outlet Obstruction
Interventions
Roux-en-Y Bypass, gastrojejunostomy
Procedure
Lead sponsor
Corewell Health West
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Oct 26, 2026, 4:54 AM EDT
Completed Phase 1 Interventional

Combination of Brivanib With 5-Fluorouracil/Leucovorin (5FU/LV) and 5-Fluorouracil/Leucovorin/Irinotecan (FOLFIRI)

NCT01046864
View directory record Official record
Conditions
Gastro-Intestinal Cancer
Interventions
5-FU, Leucovorin, Irinotecan, Brivanib
Drug
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
20 Years to 75 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
3
States / cities
Los Angeles, California • Dallas, Texas • Temple, Texas
Source: ClinicalTrials.gov public record
Updated Sep 16, 2014 · Synced Oct 26, 2026, 4:54 AM EDT
Completed Not applicable Interventional

Effect of Sugared Chewing Gum on Gastrointestinal Recovery After Major Colorectal Surgery

NCT01559662
View directory record Official record
Conditions
Postoperative Ileus
Interventions
Sugared Chewing Gum (Juicy Fruit)
Dietary Supplement
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 15, 2012 · Synced Oct 26, 2026, 4:54 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis (EUS-CPN) for Chronic Pancreatitis

NCT04403074
View directory record Official record
Conditions
Chronic Pancreatitis
Interventions
Celiac Plexus Neurolysis
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2029
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 26, 2026, 4:54 AM EDT
Completed Not applicable Interventional

Transluminal Flexible Endoscopic Procedure in Foregut and Urologic Surgery

NCT00484783
View directory record Official record
Conditions
Gastric Foreign Body, Nos, Disorder of Abdomen (Disorder), Foreign Body in Esophagus, Prostatic Diseases, Disease of Small Intestine
Interventions
Natural Orifice Transluminal Endoscopic Surgery (NOTES), Natural Orifice Translumenal Endoscopic Surgery (NOTES)
Procedure
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 16, 2014 · Synced Oct 26, 2026, 4:54 AM EDT
Completed No phase listed Observational Results available

Clinical Outcomes After Bowel Resection in Patients Receiving Alvimopan Versus Patients Not Receiving Alvimopan in the Premier Perspective Database

NCT01150760
View directory record Official record
Conditions
Ileus
Interventions
Alvimopan
Drug
Lead sponsor
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Industry
Eligibility
18 Years and older
Enrollment
7,050 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 7, 2015 · Synced Oct 26, 2026, 4:54 AM EDT
Not listed Not applicable Interventional

Nasogastric Tube Clamping Trial vs. Immediate Removal

NCT04001985
View directory record Official record
Conditions
Small Bowel Obstruction, Ileus
Interventions
No clamp trial, Clamp trial
Other
Lead sponsor
University of Illinois College of Medicine at Peoria
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Peoria, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 30, 2019 · Synced Oct 26, 2026, 4:54 AM EDT
Recruiting Phase 4 Interventional

Bilateral TAP and RS Blocks Using Liposomal Bupivacaine/Bupivacaine vs. Regular Bupivacaine in Laparoscopic Colectomy

NCT05224089
View directory record Official record
Conditions
Bowel Disease
Interventions
Liposomal Bupivicaine/Bupivacaine Admixture, Bupivacaine HCL
Drug
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Oct 26, 2026, 4:54 AM EDT
Completed Not applicable Interventional Results available

Comparison of Duodenal Stenting vs Transpyloric and Duodenal Stenting for Malignant Obstruction

NCT03125148
View directory record Official record
Conditions
Duodenal Obstruction
Interventions
Enteral stenting
Device
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 27, 2022 · Synced Oct 26, 2026, 4:54 AM EDT
Completed Not applicable Interventional

Seprafilm in the Reduction of Incidence of Bowel Obstruction in General Surgery

NCT00130715
View directory record Official record
Conditions
Intestinal Obstruction, Digestive System Surgical Procedures
Interventions
Seprafilm Bioresorbable Membrane
Device
Lead sponsor
Genzyme, a Sanofi Company
Industry
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2003
U.S. locations
16
States / cities
Scottsdale, Arizona • Los Angeles, California • Torrence, California + 11 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2015 · Synced Oct 26, 2026, 4:54 AM EDT
Completed Phase 4 Interventional

SurgiWrapTM to Reduce Soft Tissue Attachment & Incidence Early Post-Operative Bowel Obstruction in Colorectal Surgery

NCT00531739
View directory record Official record
Conditions
Adhesions, Colectomy
Interventions
Polylactic Acid Sheet
Other
Lead sponsor
Cytori Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 7, 2010 · Synced Oct 26, 2026, 4:54 AM EDT
Completed Not applicable Interventional Results available

Optimizing the Previs Device for Prediction of Postoperative Ileus

NCT03505476
View directory record Official record
Conditions
Ileus
Interventions
Entac Medical device application, Patient Daily Assessment, Patient Discharge Assessment
Device · Other
Lead sponsor
Jennifer Hrabe
Other
Eligibility
18 Years to 100 Years
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 13, 2025 · Synced Oct 26, 2026, 4:54 AM EDT
Not yet recruiting Phase 2 Interventional

SAMe in Prevention of Oxaliplatin-associated Liver Injury

NCT06258525
View directory record Official record
Conditions
Colorectal Cancer, Liver Metastases, Liver Metastasis Colon Cancer, Liver Injury, Sinusoidal Obstruction Syndrome, 5-Fluorouracil Toxicity, Liver Toxicity, Chemically-Induced
Interventions
Standard of care oxaliplatin-based chemotherapy, S-adenosylmethionine (SAMe) supplement, Surgery
Radiation · Dietary Supplement · Procedure
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 26, 2026, 4:54 AM EDT
Completed No phase listed Observational

Measurement of Body Composition by Air Displacement Plethysmography in Pediatric Intestinal Failure Patients

NCT02561819
View directory record Official record
Conditions
Short Bowel Syndrome
Interventions
Not listed
Lead sponsor
Christopher Duggan
Other
Eligibility
2 Years to 17 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Oct 26, 2026, 4:54 AM EDT
Not listed No phase listed Observational

Prospective Evaluation of the Efficacy and Safety of Submucosal Endoscopy

NCT03626350
View directory record Official record
Conditions
Gastrointestinal Neoplasia, Hirschsprung's Disease, Esophageal Obstruction, Gastroparesis, Spastic Esophageal Disorders, Zenker's Diverticulum
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
250 participants
Timeline
2018 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 21, 2024 · Synced Oct 26, 2026, 4:54 AM EDT
Terminated Not applicable Interventional Results available

Stoma Tube Decompression and Postoperative Ileus After Major Colorectal Surgery

NCT01911793
View directory record Official record
Conditions
Ileus, Bowel Obstruction
Interventions
Stoma Tube
Device
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 7, 2018 · Synced Oct 26, 2026, 4:54 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Comparison Trial of Enema vs. PEG 3350 for Constipation

NCT00467350
View directory record Official record
Conditions
Constipation
Interventions
PEG 3350, milk and molasses enema
Drug
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
1 Year to 17 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 2, 2020 · Synced Oct 26, 2026, 4:54 AM EDT
Completed Not applicable Interventional Results available

Alvimopan and Ileus in PSF

NCT02218190
View directory record Official record
Conditions
Ileus, Spinal Fusion
Interventions
Alvimopan, Placebo
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 17, 2019 · Synced Oct 26, 2026, 4:54 AM EDT
Completed Phase 2 Interventional Results available

A Study to Evaluate LB1148 for Return of Gastrointestinal Function and Adhesions in Subjects Undergoing Bowel Resection

NCT02836470
View directory record Official record
Conditions
Ileus, Post-Operative Adhesions
Interventions
LB1148, Placebo
Drug
Lead sponsor
Palisade Bio
Industry
Eligibility
18 Years to 80 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
28
States / cities
Mobile, Alabama • Yuma, Arizona • Irvine, California + 20 more
Source: ClinicalTrials.gov public record
Updated Jun 21, 2024 · Synced Oct 26, 2026, 4:54 AM EDT
Completed No phase listed Observational

Use of a Water Soluble Contrast-Based Protocol to Assist in the Management of Pediatric Adhesive Small Bowel Obstruction

NCT06101719
View directory record Official record
Conditions
Small Bowel Obstruction, Contrast Media Adverse Reaction
Interventions
Enteral contrast challenge
Diagnostic Test
Lead sponsor
Children's Hospital Colorado
Other
Eligibility
1 Year to 20 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
9
States / cities
Phoenix, Arizona • Los Angeles, California • Oakland, California + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 23, 2024 · Synced Oct 26, 2026, 4:54 AM EDT