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Showing 1–24 of 100 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Intoxication Clear all
Completed Phase 1Phase 2 Interventional Results available

A Clinical Trial to Evaluate the Safety and Efficacy of ADX-629 in in Subjects With Elevated Ethanol Levels

NCT05487404
View directory record Official record
Conditions
Ethanol Intoxication
Interventions
ADX-629, Placebo
Drug
Lead sponsor
Aldeyra Therapeutics, Inc.
Industry
Eligibility
21 Years to 65 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Jul 21, 2026, 11:18 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Drinking in Young Adult Duos (DYAD) Study

NCT06822257
View directory record Official record
Conditions
Alcohol Consumption, Alcohol Drinking, Alcohol Intoxication
Interventions
Alcohol beverage, Non-alcohol beverage
Drug · Other
Lead sponsor
Carnegie Mellon University
Other
Eligibility
21 Years to 30 Years
Enrollment
504 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 27, 2025 · Synced Jul 21, 2026, 11:18 AM EDT
Withdrawn Phase 2 Interventional

An Open-Label, Randomized Pilot Study Comparing the Safety of a Single Dose of TNX-1300 to Usual Care (UC) Alone for the Treatment of Signs and Symptoms of Acute Cocaine Intoxication in Male Emergency Department (ED) Subjects

NCT04996056
View directory record Official record
Conditions
Cocaine Intoxication
Interventions
TNX-1300, Usual Care
Drug · Other
Lead sponsor
Tonix Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 50 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Detroit, Michigan • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 28, 2022 · Synced Jul 21, 2026, 11:18 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Towards a Wearable Alcohol Biosensor: Examining the Accuracy of BAC Estimates From New-Generation Transdermal Technology Using Large-Scale Human Testing and Machine Learning Algorithms

NCT05692830
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Intoxication
Interventions
Alcohol
Drug
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
21 Years and older
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Champaign, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 5, 2025 · Synced Jul 21, 2026, 11:18 AM EDT
Completed Not applicable Interventional

Primary Care-Based Interventions to Reduce Alcohol Use Among HIV Patients

NCT01671501
View directory record Official record
Conditions
HIV, Acquired Immunodeficiency Syndrome, Alcoholism, Alcoholic Intoxication, Substance-Related Disorders
Interventions
Motivational Interviewing, Email Feedback, Usual Care
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 100 Years
Enrollment
614 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 9, 2018 · Synced Jul 21, 2026, 11:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cannabidiol Effects on Blood Alcohol Level and Intoxication

NCT06105138
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
200mg Cannabidiol oral solution, 30mg Cannabidiol oral solution, Placebo
Dietary Supplement
Lead sponsor
Colorado State University
Other
Eligibility
21 Years to 60 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 22, 2024 · Synced Jul 21, 2026, 11:18 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

A Clinical Study to Evaluate the Safety of CS-1103 in Healthy Participants

NCT06316973
View directory record Official record
Conditions
Substance Use Disorders, Methamphetamine Abuse, Methamphetamine Intoxication
Interventions
CS-1103, Sterile Saline
Drug
Lead sponsor
Clear Scientific, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Jul 21, 2026, 11:18 AM EDT
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

Rapid Reversal of CNS-Depressant Drug Effect Prior to Brain Death Determination

NCT03743805
View directory record Official record
Conditions
Brain Death, Anoxic Brain Injury, Cardiac Arrest, Sedative Intoxication, Narcotic Intoxication
Interventions
Flumazenil, Naloxone
Drug
Lead sponsor
Prisma Health-Midlands
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 30, 2024 · Synced Jul 21, 2026, 11:18 AM EDT
Completed Not applicable Interventional

Behavior and Driving Safety Study

NCT00575679
View directory record Official record
Conditions
Alcoholic Intoxication
Interventions
Brief motivational interview
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
864 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jan 3, 2019 · Synced Jul 21, 2026, 11:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Using Imaging to Assess Effects of THC on Brain Activity

NCT03655717
View directory record Official record
Conditions
Intoxication Alcohol, Intoxication THC, Intoxication Combined Alcohol THC
Interventions
Dronabinol, Ethanol, Placebo dronabinol, Placebo ethanol
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 55 Years
Enrollment
316 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 27, 2022 · Synced Jul 21, 2026, 11:18 AM EDT
Terminated Phase 2 Interventional Results available

Meth-OD: A Study of IXT-m200 in Patients With Toxicity From Methamphetamine Overdose

NCT04715230
View directory record Official record
Conditions
Methamphetamine Intoxication (Disorder)
Interventions
IXT-m200, Lorazepam, Haloperidol
Biological · Drug
Lead sponsor
InterveXion Therapeutics, LLC
Industry
Eligibility
18 Years to 45 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
4
States / cities
Little Rock, Arkansas • Albuquerque, New Mexico • Everett, Washington + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Jul 21, 2026, 11:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Group-based Intervention for Club Patrons

NCT03652688
View directory record Official record
Conditions
Drink Too Much, Drinking, Binge, Drunk, Drug Use, Aggression, Aggression Sexual, Peer Group, Safety Issues, Harm Reduction
Interventions
Nightlife Safety Plans (NSP), Fire Safety
Behavioral
Lead sponsor
Pacific Institute for Research and Evaluation
Other
Eligibility
21 Years and older
Enrollment
959 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Jul 21, 2026, 11:18 AM EDT
Recruiting No phase listed Observational

Study of an Oral Fluid Testing Approach

NCT06891235
View directory record Official record
Conditions
Cannabis Use, Cannabis Intoxication, Cannabis Use Disorder
Interventions
Biologic testing for THC
Other
Lead sponsor
Boston Children's Hospital
Other
Eligibility
18 Years to 30 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Jul 21, 2026, 11:18 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Men, Mood, and Attention Study: Examination of Alcohol, State Anger, and Emotion Regulation Sexual Aggression

NCT04192448
View directory record Official record
Conditions
Alcohol Intoxication, Anger
Interventions
Alcohol Administration, Mood Induction
Other
Lead sponsor
Elizabeth C Neilson
Other
Eligibility
21 Years to 35 Years · Male only
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Morehead, Kentucky
Source: ClinicalTrials.gov public record
Updated May 28, 2024 · Synced Jul 21, 2026, 11:18 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Alcohol and the Social Brain: An Alcohol-Administration Hyperscanning Study Employing a Within-Subject Design

NCT07125534
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Use Disorder (AUD), Alcohol Intoxication, Alcohol; Harmful Use, Alcoholism, Binge Drinking
Interventions
Alcohol beverage, Control - non alcoholic beverage
Drug · Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
21 Years to 30 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
2
States / cities
Champaign, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced Jul 21, 2026, 11:18 AM EDT
Enrolling by invitation Not applicable Interventional

Responsible Marijuana Sales Practices to Reduce the Risk of Selling to Intoxicated Customers

NCT06235632
View directory record Official record
Conditions
Alcoholic Intoxication, Automobile Accident, Cannabis
Interventions
Policy and Training Intervention, Usual and Customary Policy and Training (UC-PT) (Control) Condition
Behavioral
Lead sponsor
Klein Buendel, Inc.
Industry
Eligibility
21 Years and older
Enrollment
229 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Golden, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Jul 21, 2026, 11:18 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Neuroscience of Marijuana Impaired Driving

NCT02757313
View directory record Official record
Conditions
Marijuana Impairment
Interventions
Low dose THC marijuana, High dose THC marijuana, Placebo marijuana
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 40 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 22, 2024 · Synced Jul 21, 2026, 11:18 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Alcohol Myopia, Objectification, and Sexual Assault

NCT03956238
View directory record Official record
Conditions
Alcoholic Intoxication
Interventions
Alcohol intoxication, Objectification
Behavioral
Lead sponsor
University of Nebraska Lincoln
Other
Eligibility
21 Years to 30 Years
Enrollment
359 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Jul 9, 2023 · Synced Jul 21, 2026, 11:18 AM EDT
Completed Not applicable Interventional

WayToServe Español: Online Responsible Beverage Service Training for Spanish-Speaking Servers

NCT03001024
View directory record Official record
Conditions
Alcoholic Intoxication
Interventions
Implementation of WayToServe Español, Usual and Customary RBS Training
Behavioral
Lead sponsor
Klein Buendel, Inc.
Industry
Eligibility
18 Years and older
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
2
States / cities
Golden, Colorado • El Paso, Texas
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Jul 21, 2026, 11:18 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Computer-Assisted Self-Administration of Ethanol

NCT00713492
View directory record Official record
Conditions
Alcoholic Intoxication
Interventions
Alcohol
Drug
Lead sponsor
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
NIH
Eligibility
21 Years to 60 Years
Enrollment
229 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2023
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Jul 21, 2026, 11:18 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

WayToServePlus: Improving Responsible Alcohol Service Ph II

NCT05779774
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Intoxication, Alcohol Use, Unspecified
Interventions
WayToServe Plus In-service Component, WayToServe Training Only
Behavioral
Lead sponsor
Klein Buendel, Inc.
Industry
Eligibility
19 Years and older
Enrollment
1,172 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Golden, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Jul 21, 2026, 11:18 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Biphasic Effects of Acute Alcohol Intoxication on Bystander Intervention

NCT05701865
View directory record Official record
Conditions
Alcohol Intoxication
Interventions
Alcohol Intoxication- Ascending Limb, Alcohol Intoxication- Descending Limb, No Alcohol Control
Behavioral
Lead sponsor
Georgia State University
Other
Eligibility
21 Years to 30 Years
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 11, 2024 · Synced Jul 21, 2026, 11:18 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Alcohol Impairment Detection in Healthy Adult Users With the Gaize Device

NCT07126938
View directory record Official record
Conditions
Alcohol Impairment, Nystagmus, Virtual Reality, Lack of Smooth Pursuit, Impairment, Alcohol Intoxication, Intoxication
Interventions
Alcoholic beverage
Drug
Lead sponsor
Gaize
Industry
Eligibility
21 Years to 45 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Missoula, Montana
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Jul 21, 2026, 11:18 AM EDT
Recruiting Phase 1 Interventional

Influence of Mavoglurant on Alcohol Craving and Drinking in Heavy Drinkers

NCT06136195
View directory record Official record
Conditions
Alcohol Consumption, Heavy Drinker, Alcohol Use Disorder (AUD)
Interventions
Mavoglurant
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 50 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Jul 21, 2026, 11:18 AM EDT