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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Intracranial Aneurysm Clear all
Active, not recruiting Phase 2 Interventional

Minocycline for Aneurysmal Subarachnoid Hemorrhage (MASH)

NCT04876638
View directory record Official record
Conditions
Aneurysm, Ruptured, Vasospasm, Intracranial, Delayed Cerebral Ischemia, Blood Brain Barrier Defect
Interventions
Minocyclin
Drug
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Jul 21, 2026, 9:24 PM EDT
Terminated Not applicable Interventional Results available

Study to Evaluate the Safety and Effectiveness of the CODMAN ENTERPRISE® Vascular Reconstruction Device

NCT02532517
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
CODMAN ENTERPRISE® Vascular Reconstruction Device and Delivery System
Device
Lead sponsor
Cerenovus, Part of DePuy Synthes Products, Inc.
Industry
Eligibility
21 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
11
States / cities
Englewood, Colorado • Gainesville, Florida • Jacksonville, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Oct 22, 2020 · Synced Jul 21, 2026, 9:24 PM EDT
Suspended No phase listed Observational

Intraoperative Laser Speckle Contrast Imaging of Cerebral Blood Flow

NCT04865718
View directory record Official record
Conditions
Aneurysm, Brain, Arteriovenous Malformation of Brain, Neurovascular Disorder
Interventions
ICGA imaging
Diagnostic Test
Lead sponsor
Andrew Dunn
Other
Eligibility
18 Years and older
Enrollment
20 participants
Timeline
2019 – 2028
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Jul 21, 2026, 9:24 PM EDT
Completed Phase 1 Interventional

Influence of MMP on Brain AVM Hemorrhage

NCT00783523
View directory record Official record
Conditions
Arteriovenous Malformations, Cavernous Angiomas, Brain Aneurysms
Interventions
Doxycycline or Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
13 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Aug 8, 2013 · Synced Jul 21, 2026, 9:24 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Hypovitaminosis D in Neurocritical Patients

NCT02881957
View directory record Official record
Conditions
Craniocerebral Trauma, Intracranial Aneurysm, Brain Neoplasms, Spinal Cord Injuries, Seizures, Meningitis, Stroke, Intracranial Hemorrhages, Critical Illness, Vitamin d Deficiency
Interventions
Cholecalciferol, Placebo
Drug · Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 14, 2022 · Synced Jul 21, 2026, 9:24 PM EDT
Completed Phase 4 Interventional

Aneurysm Wall Histology Registry

NCT01444664
View directory record Official record
Conditions
Brain Aneurysm
Interventions
Surgical Clipping of Aneurysm
Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
9
States / cities
Chicago, Illinois • Indianapolis, Indiana • Albany, New York + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 23, 2016 · Synced Jul 21, 2026, 9:24 PM EDT
Active, not recruiting Not applicable Interventional

International Subarachnoid Aneurysm Trial II

NCT01668563
View directory record Official record
Conditions
Intracranial Hemorrhage Ruptured Aneurysm
Interventions
surgical management, Endovascular management
Procedure
Lead sponsor
Centre hospitalier de l'Université de Montréal (CHUM)
Other
Eligibility
18 Years and older
Enrollment
1,724 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2024
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 14, 2024 · Synced Jul 21, 2026, 9:24 PM EDT
Completed Not applicable Interventional Results available

Hydrogel Endovascular Aneurysm Treatment Trial

NCT01407952
View directory record Official record
Conditions
Cerebral Aneurysm
Interventions
HydroCoil Embolic System, Control (bare platinum coils)
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 75 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
38
States / cities
Phoenix, Arizona • Sacramento, California • Newark, Delaware + 31 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2019 · Synced Jul 21, 2026, 9:24 PM EDT
Recruiting Phase 2 Interventional

Effect of Sirolimus on Molecular Alterations in Cerebral Aneurysms

NCT04141020
View directory record Official record
Conditions
Cerebral Aneurysm
Interventions
Microsurgical clipping, Endovascular treatment, Sirolimus
Procedure · Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Jul 21, 2026, 9:24 PM EDT
Completed No phase listed Observational Results available

TransForm™ Occlusion Balloon Catheter Registry

NCT01949779
View directory record Official record
Conditions
Intracranial Aneurysms
Interventions
TransForm™ Occlusion Balloon Catheter
Device
Lead sponsor
Stryker Neurovascular
Industry
Eligibility
18 Years to 80 Years
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
6
States / cities
Palm Springs, California • Lexington, Kentucky • Worcester, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2019 · Synced Jul 21, 2026, 9:24 PM EDT
Completed Phase 2 Interventional Results available

Evaluating Neuroprotection in Aneurysm Coiling Therapy

NCT00728182
View directory record Official record
Conditions
Stroke
Interventions
NA-1, Placebo
Drug
Lead sponsor
NoNO Inc.
Industry
Eligibility
18 Years and older
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
3
States / cities
Phoenix, Arizona • Stanford, California • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 16, 2013 · Synced Jul 21, 2026, 9:24 PM EDT
Withdrawn Phase 2 Interventional

Clevidipine for Vasospasm After Subarachnoid Hemorrhage (SAH)

NCT02011321
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Cerebral Aneurysm, Vasospasm, Intracranial
Interventions
clevidipine
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 31, 2023 · Synced Jul 21, 2026, 9:24 PM EDT
Active, not recruiting Not applicable Interventional

Kaneka Endovascular Embolization and Protection

NCT05563051
View directory record Official record
Conditions
Aneurysm Cerebral
Interventions
i-ED COIL
Device
Lead sponsor
Kaneka Medical America LLC
Industry
Eligibility
18 Years to 80 Years
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
4
States / cities
Grand Blanc, Michigan • New York, New York • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Jul 21, 2026, 9:24 PM EDT
Completed Phase 3 Interventional

Simvastatin in Aneurysmal Subarachnoid Haemorrhage (STASH) a Multicentre Randomised Controlled Clinical Trial

NCT00731627
View directory record Official record
Conditions
Subarachnoid Haemorrhage
Interventions
placebo, simvastatin
Drug
Lead sponsor
Cambridge University Hospitals NHS Foundation Trust
Other
Eligibility
18 Years to 65 Years
Enrollment
803 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
2
States / cities
Gainesville, Florida • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 24, 2014 · Synced Jul 21, 2026, 9:24 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Feasibility Study of the LVIS™ (Low-profile Visualized Intraluminal Support)Device

NCT01541254
View directory record Official record
Conditions
Intracranial Aneurysms
Interventions
Low profile Visualized Intraluminal Device (LVIS and LVIS Jr.)
Device
Lead sponsor
Microvention-Terumo, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
6
States / cities
Albany, New York • Stony Brook, New York • Philadelphia, Pennsylvania + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2025 · Synced Jul 21, 2026, 9:24 PM EDT
Completed Not applicable Interventional Results available

Goal-Directed Intraoperative Fluid Management Using FloTrac© Monitoring in High-Risk Neurosurgical Patients

NCT02701582
View directory record Official record
Conditions
Intracranial Aneurysm, Brain Edema, Scoliosis, Surgery
Interventions
Phenylephrine, Epinephrine, Albumin, Voluven, Normal Saline, Packed Red Blood Cells, FloTrac Monitor
Drug · Other · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
15 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 27, 2019 · Synced Jul 21, 2026, 9:24 PM EDT
Recruiting Not applicable Interventional

The Use of p48/64 MW HPC Flow Modulation Device in the Treatment of Wide-necked Intracranial Aneurysms

NCT07143019
View directory record Official record
Conditions
Hemorrhagic Stroke, Aneurysm, Intracranial, Saccular Aneurysm, Fusiform Aneurysm, Brain Aneurysm
Interventions
Flow diversion
Device
Lead sponsor
phenox Inc.
Industry
Eligibility
18 Years and older
Enrollment
214 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
21
States / cities
Phoenix, Arizona • San Francisco, California • Aurora, Colorado + 17 more
Source: ClinicalTrials.gov public record
Updated Jul 5, 2026 · Synced Jul 21, 2026, 9:24 PM EDT
Completed Phase 2 Interventional

Balloon Prophylaxis of Aneurysmal Vasospasm

NCT00282893
View directory record Official record
Conditions
Aneurysm, Vasospasm
Interventions
transluminal ballooning, currently existing therapies for the treatment of vasospasm
Procedure · Other
Lead sponsor
University of California, Davis
Other
Eligibility
17 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2006
U.S. locations
3
States / cities
Sacramento, California • Nashville, Tennessee • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 14, 2017 · Synced Jul 21, 2026, 9:24 PM EDT
Terminated No phase listed Observational

CARE: A Prospective Multicenter Case Study to Assess Radiation Exposure in Patients Treated With the Penumbra Coil 400

NCT02122133
View directory record Official record
Conditions
Intracranial Aneurysms
Interventions
PC 400
Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
Not listed
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Bellevue, Washington
Source: ClinicalTrials.gov public record
Updated Apr 11, 2019 · Synced Jul 21, 2026, 9:24 PM EDT
Withdrawn Not applicable Interventional

Analysis Of Intracranial Artery Lesions Using 2-D/3D Phase Contrast MR

NCT00710281
View directory record Official record
Conditions
Intracranial Arterial Aneurysm
Interventions
Additional scan time on standard MR angiography
Radiation
Lead sponsor
Lahey Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Burlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 17, 2013 · Synced Jul 21, 2026, 9:24 PM EDT
Completed No phase listed Observational

Optical Coherence Tomography Imaging of Post Coil Aneurysm Healing.

NCT00556309
View directory record Official record
Conditions
Cerebral Aneurysm
Interventions
Optical Coherence Tomography
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
2
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2022 · Synced Jul 21, 2026, 9:24 PM EDT
Completed No phase listed Observational

Doppler Flow Wires in Cerebral Angiography

NCT03145701
View directory record Official record
Conditions
Aneurysm, Cerebral Aneurysm
Interventions
Not listed
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 30, 2020 · Synced Jul 21, 2026, 9:24 PM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Induced Suppression of Platelet Activity in Aneurysmal Subarachnoid Hemorrhage Management-2 (iSPASM-2)

NCT07493577
View directory record Official record
Conditions
Aneurysmal Subarachnoid Hemorrhage
Interventions
Tirofiban, Placebo
Drug
Lead sponsor
Dr David Hasan, M.D.
Other
Eligibility
18 Years to 85 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
2
States / cities
Durham, North Carolina • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Jul 21, 2026, 9:24 PM EDT
Withdrawn Not applicable Interventional

Decision Aids in Cerebral Aneurysm Treatment

NCT02503553
View directory record Official record
Conditions
Cerebral Aneurysm
Interventions
Option grid for cerebral aneurysm treatment, Control
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Feb 2, 2016 · Synced Jul 21, 2026, 9:24 PM EDT