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ClinicalTrials.gov public records Last synced Sep 17, 2026, 7:42 AM EDT

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Showing 1–24 of 255 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Intracranial Arterial Diseases Clear all
Completed No phase listed Observational

Osmotic Agent Use in Middle Cerebral Artery Stroke

NCT04156490
View directory record Official record
Conditions
Ischemic Stroke, MCA Infarction
Interventions
No intervention is planned, this will be a purely retrospective trial.
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 6, 2019 · Synced Sep 17, 2026, 7:42 AM EDT
Completed Not applicable Interventional Results available

All About Me: An Intervention to Ease the Transition to Long Term Care

NCT05516134
View directory record Official record
Conditions
Dementia, Alzheimer Disease, Dementia, Vascular, Dementia, Mixed, Dementia of Alzheimer Type
Interventions
SAFE at Home
Behavioral
Lead sponsor
Hopeful Aging
Industry
Eligibility
60 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Winchester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 28, 2025 · Synced Sep 17, 2026, 7:42 AM EDT
Completed No phase listed Observational Results available

Assessing the WAVE Extra Soft Coil in Intracranial Aneurysms and Comparing Imaging Modalities

NCT04106583
View directory record Official record
Conditions
Aneurysm, Brain
Interventions
WAVE, as part of the SMART COIL System
Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
18 Years and older
Enrollment
572 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
34
States / cities
Dothan, Alabama • Tucson, Arizona • La Mesa, California + 29 more
Source: ClinicalTrials.gov public record
Updated Mar 3, 2025 · Synced Sep 17, 2026, 7:42 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Feasibility Study of the LVIS™ (Low-profile Visualized Intraluminal Support)Device

NCT01541254
View directory record Official record
Conditions
Intracranial Aneurysms
Interventions
Low profile Visualized Intraluminal Device (LVIS and LVIS Jr.)
Device
Lead sponsor
Microvention-Terumo, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
6
States / cities
Albany, New York • Stony Brook, New York • Philadelphia, Pennsylvania + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2025 · Synced Sep 17, 2026, 7:42 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

n-3 PUFA for Vascular Cognitive Aging

NCT01953705
View directory record Official record
Conditions
Age Related Cognitive Decline, Alzheimer's Disease, Vascular Dementia, Endothelial Dysfunction, Executive Dysfunction
Interventions
Omega 3 PUFA, Placebo
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
75 Years and older
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 3, 2020 · Synced Sep 17, 2026, 7:42 AM EDT
Completed Not applicable Interventional Results available

Cognitive Stimulation Therapy for Dementia: A Two-Armed Pragmatic Trial

NCT05860127
View directory record Official record
Conditions
Dementia, Cognitive Impairment, Mild, Dementia, Vascular, Dementia, Mixed, Dementia With Lewy Bodies, Dementia Frontal, Dementia Moderate, Dementia of Alzheimer Type, Dementia, Mild
Interventions
Referral for Cognitive Stimulation Therapy, No change to Standard of Care
Behavioral · Other
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
18 Years and older
Enrollment
133 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Farmington, Connecticut • New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Sep 17, 2026, 7:42 AM EDT
Completed Not applicable Interventional Results available

Palliative Care for Persons With Late-stage Alzheimer's and Related Dementias and Their Caregivers

NCT04948866
View directory record Official record
Conditions
Dementia, Dementia, Vascular, Dementia With Lewy Bodies, Dementia Frontal, Dementia, Mixed, Dementia Alzheimers, Alzheimer Disease, Dementia Severe
Interventions
ADRD-PC Program
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
55 Years and older
Enrollment
884 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
5
States / cities
Denver, Colorado • Atlanta, Georgia • Indianapolis, Indiana + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Sep 17, 2026, 7:42 AM EDT
Not listed No phase listed Observational

Aneurysm Genetic Risk in Patients With QIB Changes

NCT05317169
View directory record Official record
Conditions
Brain Aneurysm
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated May 7, 2023 · Synced Sep 17, 2026, 7:42 AM EDT
Terminated Phase 4 Interventional Results available

The Intra-arterial Vasospasm Trial

NCT01996436
View directory record Official record
Conditions
Cerebral Vasospasm
Interventions
Nicardipine, Verapamil, Nicardipine + Verapamil + Nitroglycerin
Drug
Lead sponsor
Peng Roc Chen, MD
Other
Eligibility
18 Years to 80 Years
Enrollment
92 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
5
States / cities
New Haven, Connecticut • Manhasset, New York • Winston-Salem, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated May 10, 2025 · Synced Sep 17, 2026, 7:42 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Clopidogrel Hyper-Responsiveness: Incidence and Associated Outcomes in Patients With Cerebral Aneurysms

NCT05945563
View directory record Official record
Conditions
Cerebral Aneurysm
Interventions
Not listed
Lead sponsor
Methodist Health System
Other
Eligibility
18 Years to 85 Years
Enrollment
208 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 17, 2026, 7:42 AM EDT
Completed Not applicable Interventional

Auburn University Research on Olive Oil for Alzheimer's Disease (AU-ROOAD)

NCT03824197
View directory record Official record
Conditions
Alzheimer Disease, Cerebral Amyloid Angiopathy
Interventions
EVOO, OO
Other
Lead sponsor
Auburn University
Other
Eligibility
55 Years to 75 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 1, 2021 · Synced Sep 17, 2026, 7:42 AM EDT
Recruiting Not applicable Interventional

A Phase II Trial of Fetal Embolization for Vein of Galen Malformation

NCT07483255
View directory record Official record
Conditions
Vein of Galen Malformations
Interventions
Fetal embolization of vein of Galen malformation using Target XL and XXL Detachable Coils
Device
Lead sponsor
Darren Orbach
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Sep 17, 2026, 7:42 AM EDT
Recruiting No phase listed Observational

Product Surveillance Registry

NCT01524276
View directory record Official record
Conditions
Cardiac Rhythm Disorders, Urological Disorders, Neurological Disorders, Cardiovascular Disorders, Digestive Disorders, Intracranial Aneurysm, Mechanical Circulatory Support, Respiratory Therapy, Aortic, Peripheral Vascular and Venous Disorders, Minimally Invasive Surgical Procedures, Diagnostic Techniques and Procedures, Surgical Procedures, Operative, Renal Insufficiency, Neurovascular, Coronary Artery Disease, Ear, Nose and Throat Disorder
Interventions
Not listed
Lead sponsor
Medtronic
Industry
Eligibility
Not listed
Enrollment
100,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2040
U.S. locations
134
States / cities
Birmingham, Alabama • Huntsville, Alabama • Chandler, Arizona + 131 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Sep 17, 2026, 7:42 AM EDT
Completed No phase listed Observational

Intraoperative Fluorescence With Augmented Reality

NCT03888014
View directory record Official record
Conditions
Vascular; Lesion, Central Nervous System, Brain Tumor, Cerebral Aneurysm, Cerebral AVM
Interventions
GLOW800, indocyanine green (ICG)
Device · Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 17, 2023 · Synced Sep 17, 2026, 7:42 AM EDT
Not listed No phase listed Observational

Predictors of Intracranial Atherosclerotic Disease in Posterior Circulation: a Cohort Study

NCT06453252
View directory record Official record
Conditions
Stroke, Ischemic, Intracranial Atherosclerosis, Posterior Circulation Brain Infarction
Interventions
we are aiming to develop a Scoring system based on certain variables derived from both groups
Other
Lead sponsor
Sohag University
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 9, 2024 · Synced Sep 17, 2026, 7:42 AM EDT
Not listed Not applicable Interventional

Prospective Packing Density With Target Coils I

NCT02292017
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
Embolization of intracranial aneurysm
Device
Lead sponsor
Tennessee Neurovascular Institute, LLC
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Sep 17, 2026, 7:42 AM EDT
Completed Not applicable Interventional Results available

Study of the Penumbra Coil 400 System to Treat Aneurysm

NCT01465841
View directory record Official record
Conditions
Intracranial Aneurysms, Peripheral Aneurysms
Interventions
PC 400 coils (Penumbra )
Device
Lead sponsor
Penumbra Inc.
Industry
Eligibility
Not listed
Enrollment
517 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
6
States / cities
Newport Beach, California • Chicago, Illinois • New York, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 6, 2020 · Synced Sep 17, 2026, 7:42 AM EDT
Completed Not applicable Interventional Results available

Optimizing Dementia Care

NCT02585232
View directory record Official record
Conditions
Alzheimer's Disease, Dementia, Dementia, Vascular, Caregivers, Veterans
Interventions
Counseling (C), Care Consultation (CC)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
19 Years and older
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 10, 2022 · Synced Sep 17, 2026, 7:42 AM EDT
Completed Phase 4 Interventional Results available

Reducing Total Cardiovascular Risk in an Urban Community

NCT00241904
View directory record Official record
Conditions
Cardiovascular Diseases, Heart Diseases, Coronary Disease, Diabetes Mellitus, Atherosclerosis, Cerebral Arteriosclerosis, Hypertension
Interventions
Lifestyle Changes, Antiplatelet Agents, Beta Blocker, ACE Inhibitors
Behavioral · Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 80 Years
Enrollment
525 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 14, 2017 · Synced Sep 17, 2026, 7:42 AM EDT
Active, not recruiting Not applicable Interventional

Evaluation of Flow Diverter Technology Device for Intracranial Aneurysm

NCT06411418
View directory record Official record
Conditions
Intracranial Aneurysms
Interventions
Pipeline™ Flex Embolization Device with Shield Technology™
Device
Lead sponsor
Jacobs institute
Other
Eligibility
22 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Sep 17, 2026, 7:42 AM EDT
Withdrawn Not applicable Interventional

Remote Ischemic PreConditioning (RIPC)

NCT03814850
View directory record Official record
Conditions
Unruptured Cerebral Aneurysm
Interventions
Standard Manual Aneroid Sphygmomanometer
Device
Lead sponsor
Sebastian Koch
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Dec 7, 2023 · Synced Sep 17, 2026, 7:42 AM EDT
Completed No phase listed Observational

Testing of Identification Markers for Stroke

NCT04292600
View directory record Official record
Conditions
Stroke, Ischemic, Infarction, Middle Cerebral Artery, Infarction, Anterior Circulation, Brain
Interventions
POCKiT diagnostics' algorithm for LVO detection
Diagnostic Test
Lead sponsor
POCKiT diagnostics Ltd
Industry
Eligibility
18 Years and older
Enrollment
383 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
3
States / cities
Birmingham, Alabama • Brandon, Florida • Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Apr 2, 2023 · Synced Sep 17, 2026, 7:42 AM EDT
Recruiting Not applicable Interventional

Safety, Feasibility, and Efficacy of Non-invasive Vagus Nerve Stimulation (nVNS) in the Treatment of Aneurysmal Subarachnoid Hemorrhage

NCT05103566
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Aneurysmal
Interventions
gammaCore
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Sep 17, 2026, 7:42 AM EDT
Terminated Not applicable Interventional Results available

Pipeline™ Vantage Embolization Device With Shield Technology™ for Wide-Necked Intracranial Aneurysms (ADVANCE)

NCT03873714
View directory record Official record
Conditions
Intracranial Aneurysm
Interventions
Pipeline™ Vantage Embolization Device with Shield Technology™
Device
Lead sponsor
Medtronic Neurovascular Clinical Affairs
Industry
Eligibility
22 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
3
States / cities
Jacksonville, Florida • Miami, Florida • Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Sep 17, 2026, 7:42 AM EDT