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ClinicalTrials.gov public records Last synced Sep 11, 2026, 5:32 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Intraocular Lens Clear all
Completed Phase 4 Interventional Accepts healthy volunteers

Evaluation of a Monofocal Intraocular Lens

NCT06428955
View directory record Official record
Conditions
Cataract
Interventions
CT LUCIA 621P
Device
Lead sponsor
Carl Zeiss Meditec AG
Industry
Eligibility
50 Years and older
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
3
States / cities
Indianapolis, Indiana • Lexington, Kentucky • Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Sep 11, 2026, 5:32 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Artisan Aphakia Lens for the Correction of Aphakia in Children

NCT01547442
View directory record Official record
Conditions
Aphakia
Interventions
Artisan Aphakia Intraocular Lens
Device
Lead sponsor
Ophtec USA
Industry
Eligibility
2 Years to 21 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2025
U.S. locations
18
States / cities
Phoenix, Arizona • Los Angeles, California • Indianapolis, Indiana + 15 more
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Sep 11, 2026, 5:32 AM EDT
Completed Not applicable Interventional Results available

Clinical Trial of a Hydrophilic EMV Toric Lens RAO210T in the Correction of Aphakia and Corneal Astigmatism

NCT05985304
View directory record Official record
Conditions
Cataract, Corneal Astigmatism
Interventions
RayOne EMV Toric IOL, RayOne Monofocal IOL, Cataract Surgery
Device · Procedure
Lead sponsor
Rayner Intraocular Lenses Limited
Industry
Eligibility
22 Years and older
Enrollment
274 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
9
States / cities
Fayetteville, Arkansas • Grand Junction, Colorado • Alexandria, Minnesota + 6 more
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 11, 2026, 5:32 AM EDT
Terminated Not applicable Interventional Results available

Capsular Tension Rings in Intraocular Lens Rotation

NCT04436198
View directory record Official record
Conditions
Cataract, Ophthalmoplegia, Ophthalmologic Complication
Interventions
MORCHER® EYEJET® CTR Types 14, 14A, and 14C, Toric IOL Only
Device
Lead sponsor
Rachel Lieberman
Federal
Eligibility
30 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Nellis Air Force Base, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 18, 2024 · Synced Sep 11, 2026, 5:32 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Vision After Vivity IOL Implantation With a Target of Slight Myopia in the Non-dominant Eye

NCT04482439
View directory record Official record
Conditions
Cataract
Interventions
Vivity Extended Depth of Focus intraocular lens (IOL)
Device
Lead sponsor
Newsom Eye & Laser Center
Other
Eligibility
40 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Sebring, Florida
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Sep 11, 2026, 5:32 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparative Study of Photopic and Mesopic Distance, Intermediate and Near Visual Acuity, and Spectacle Independence

NCT01191502
View directory record Official record
Conditions
Visual Acuity
Interventions
Not listed
Lead sponsor
Innovative Medical
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 5, 2011 · Synced Sep 11, 2026, 5:32 AM EDT
Completed Phase 4 Interventional

Comparison of Postoperative Visual Acuity and Spectacle Independence Between the Tecnis Multifocal Intraoculer Lens (IOL) and the Crystalens Accommodating IOL

NCT01275118
View directory record Official record
Conditions
Cataract
Interventions
Tecnis Multifocal IOL, crystalens Accommodating IOL
Device
Lead sponsor
Mark Packer, MD, FACS
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 27, 2014 · Synced Sep 11, 2026, 5:32 AM EDT
Completed Not applicable Interventional

AT ELANA 841P Posterior Chamber Intraocular Lens for Correction of Aphakia Following Cataract Removal

NCT06264232
View directory record Official record
Conditions
Cataract Senile
Interventions
Cataract Surgery
Device
Lead sponsor
Carl Zeiss Meditec, Inc.
Industry
Eligibility
22 Years to 100 Years
Enrollment
284 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
14
States / cities
Beverly Hills, California • Northridge, California • Orange, California + 11 more
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Sep 11, 2026, 5:32 AM EDT
Completed Phase 4 Interventional Results available

Visual Function After Implantation of Bilateral AcrySof® Toric Natural Intraocular Lens

NCT00760487
View directory record Official record
Conditions
Cataract
Interventions
AcrySof Toric IOL
Device
Lead sponsor
Alcon Research
Industry
Eligibility
21 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jan 15, 2012 · Synced Sep 11, 2026, 5:32 AM EDT
Terminated No phase listed Observational

Using the Optovue OCT to Select IOL Power

NCT01361282
View directory record Official record
Conditions
Fuchs' Endothelial Dystrophy, Cataract
Interventions
Not listed
Lead sponsor
Legacy Health System
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 12, 2017 · Synced Sep 11, 2026, 5:32 AM EDT
Completed Not applicable Interventional

Post Market Clinical Follow-up (PMCF) Study of Clareon Vivity & Clareon PanOptix

NCT05796453
View directory record Official record
Conditions
Aphakia, Astigmatism, Presbyopia
Interventions
Clareon Vivity IOL - Non Toric, Clareon Vivity IOL - Toric, Clareon PanOptix Trifocal IOL - Non Toric, Clareon PanOptix Trifocal IOL - Toric
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
470 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
6
States / cities
Torrance, California • Jacksonville, Florida • Liverpool, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 11, 2026, 5:32 AM EDT
Not listed Not applicable Interventional

Visual Acuity Outcome Differences Between the Alcon Vivity Toric IOL and RxSight LAL+

NCT06574646
View directory record Official record
Conditions
Cataract
Interventions
LAL+, Clareon Vivity Toric IOL
Device
Lead sponsor
The Eye Associates
Other
Eligibility
45 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Sep 11, 2026, 5:32 AM EDT
Completed No phase listed Observational

Refractive Accuracy of Toric Intraocular Lens Implantation Using Digital Marking Compared to Conventional Marking

NCT07176897
View directory record Official record
Conditions
Cataract, Astigmatism
Interventions
Normal Toric IOL implantation with digital marking
Diagnostic Test
Lead sponsor
Colvard Kandavel Eye Center
Other
Eligibility
50 Years to 90 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Encino, California
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Sep 11, 2026, 5:32 AM EDT
Completed No phase listed Observational

A Study to Evaluate the enVista® Aspire (EA) Intraocular Lens in Subjects Undergoing Cataract Extraction

NCT06333028
View directory record Official record
Conditions
Cataract
Interventions
enVista Aspire EA IOLs
Device
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
22 Years and older
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
7
States / cities
Dover, New Jersey • Woodland Park, New Jersey • Garden City, New York + 4 more
Source: ClinicalTrials.gov public record
Updated May 1, 2025 · Synced Sep 11, 2026, 5:32 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Comparison of Visual Outcomes With Mini-Monovision Between a Monofocal and an Adjustable Intraocular Lens

NCT06122103
View directory record Official record
Conditions
Cataract
Interventions
Clareon Monofocal, Light-Adjustable Lens
Device
Lead sponsor
Gainesville Eye Associates
Other
Eligibility
18 Years and older
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Gainesville, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Sep 11, 2026, 5:32 AM EDT
Recruiting Phase 4 Interventional

A Prospective, Randomized, Subject- and Examiner-Masked, Multicenter Study Comparing Bilateral Clareon TruPlus and Bilateral Clareon Monofocal Intraocular Lens Implantation (Spherical and Toric) in Cataract Subjects

NCT07693205
View directory record Official record
Conditions
Cataract
Interventions
Clareon TruPlus, Clareon monofocal
Device
Lead sponsor
Berkeley Eye Center
Other
Eligibility
22 Years and older
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Sugar Land, Texas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 11, 2026, 5:32 AM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety of Bromfenac Ophthalmic Solution in Cataract Surgery

NCT00703781
View directory record Official record
Conditions
Cataract
Interventions
bromfenac ophthalmic solution, placebo
Drug
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Mar 23, 2015 · Synced Sep 11, 2026, 5:32 AM EDT
Completed Phase 2 Interventional

Iontophoretic Delivery of EGP-437 in Patients Who Have Undergone Cataract Surgery

NCT03180255
View directory record Official record
Conditions
Cataract, Anterior Chamber Inflammation, Pain, Postoperative
Interventions
Dexamethasone phosphate, Placebo
Combination Product · Other
Lead sponsor
Eyegate Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated May 20, 2018 · Synced Sep 11, 2026, 5:32 AM EDT
Completed Phase 3 Interventional Results available

Loteprednol vs Prednisolone for the Treatment of Intraocular Inflammation Following Cataract Surgery in Children.

NCT01475643
View directory record Official record
Conditions
Cataract
Interventions
Loteprednol etabonate, Prednisolones acetate
Drug
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
Up to 11 Years
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 10, 2019 · Synced Sep 11, 2026, 5:32 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Clinical Investigation of Expanded Designs of a Multifocal IOL

NCT01714635
View directory record Official record
Conditions
Cataract
Interventions
Tecnis Multifocal Intraocular Lens, Monofocal Intraocular Lens
Device
Lead sponsor
Abbott Medical Optics
Industry
Eligibility
18 Years and older
Enrollment
445 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
17
States / cities
Tucson, Arizona • Rogers, Arkansas • Bakersfield, California + 14 more
Source: ClinicalTrials.gov public record
Updated Mar 16, 2015 · Synced Sep 11, 2026, 5:32 AM EDT
Completed No phase listed Observational Results available

Effect of Intraocular Lens (IOL) Centration and Tilt on Visual Performance With Clareon® Vivity® IOL Implantation

NCT05827133
View directory record Official record
Conditions
Cataract, Lenses, Intraocular
Interventions
No intervention
Other
Lead sponsor
East Coast Institute for Research
Network
Eligibility
18 Years and older
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Sep 11, 2026, 5:32 AM EDT
Enrolling by invitation No phase listed Observational

Long-Term Clinical Outcomes Of Subjects Enrolled In The RxSight Light Adjustable Lens (LAL) And Light Delivery Device (LDD) New Enrollment Study

NCT07347379
View directory record Official record
Conditions
Aphakia Cataract
Interventions
Light Adjustable lens (LAL) and Light Delivery Device (LDD)
Device
Lead sponsor
RxSight, Inc.
Industry
Eligibility
Not listed
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Sep 11, 2026, 5:32 AM EDT
Completed Not applicable Interventional Results available

ACRYSOF® Toric NATURAL T9 Intraocular Lens (IOL)

NCT00967473
View directory record Official record
Conditions
Bilateral Cataract
Interventions
ACRYSOF® Single-Piece NATURAL Toric IOL Model SN60T9 and Model SN60T8.
Device
Lead sponsor
Alcon Research
Industry
Eligibility
21 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jan 8, 2017 · Synced Sep 11, 2026, 5:32 AM EDT
Terminated Not applicable Interventional Results available

A Clinical Study Comparing Postoperative Outcomes Between the TECNIS Intraocular Lens.

NCT05396599
View directory record Official record
Conditions
Cataract
Interventions
Model DIU, Model DFW, Model ZCT
Device
Lead sponsor
Johnson & Johnson Surgical Vision, Inc.
Industry
Eligibility
22 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
5
States / cities
Los Angeles, California • Orange, California • San Francisco, California + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2024 · Synced Sep 11, 2026, 5:32 AM EDT