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Showing 1–24 of 100 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Intrauterine Device Clear all
Withdrawn Phase 2Phase 3 Interventional Accepts healthy volunteers

Nitrous Oxide for Pain Management During IUD Insertion in Nulliparous Adolescent Women

NCT04089852
View directory record Official record
Conditions
Contraceptive Devices, Long-Acting Reversible Contraception, Analgesia, Adolescent Health, Gynecology
Interventions
Nitrous oxide gas for inhalation, Oxygen Gas for Inhalation
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
14 Years to 24 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 15, 2022 · Synced Sep 3, 2026, 9:43 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effect of a Levonorgestrel-releasing Intrauterine Device (IUD) Versus a Copper Containing IUD on Risk of Blood Clots

NCT00584610
View directory record Official record
Conditions
Blood Coagulation Disorders
Interventions
Levonorgestrel-containing IUD (Mirena®), Copper-containing IUD (Paraguard®)
Device
Lead sponsor
University of Vermont
Other
Eligibility
18 Years to 52 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jan 17, 2010 · Synced Sep 3, 2026, 9:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of the PelvicSim Simulator for Training in Intrauterine Device Insertions

NCT02220205
View directory record Official record
Conditions
Contraceptive Devices, Intrauterine, Education, Medical
Interventions
PelvicSim, Manufacturer model
Other · Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
Not listed
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 23, 2017 · Synced Sep 3, 2026, 9:43 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Patient-centered Information on Permanent Contraception

NCT06296797
View directory record Official record
Conditions
Contraception, Reproductive Behavior, Contraception Behavior
Interventions
Control arm: Existing educational website, Advancing Access Website
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
21 Years to 45 Years · Female only
Enrollment
650 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced Sep 3, 2026, 9:43 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

A Multicenter Analysis of Levonorgestrel-Intrauterine System (LNG-IUS) Use in the Postpartum Period

NCT01161095
View directory record Official record
Conditions
Contraception, Postpartum Period
Interventions
LNG-IUS
Device
Lead sponsor
United States Naval Medical Center, Portsmouth
Federal
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
2
States / cities
Little Rock, Arkansas • Portsmouth, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 19, 2025 · Synced Sep 3, 2026, 9:43 PM EDT
Completed Phase 4 Interventional Results available

Intrauterine Contraceptive Device (IUD) Placement at Time of C-Section

NCT00733278
View directory record Official record
Conditions
Contraception
Interventions
Copper IUD ( ParaGard Intrauterine Contraceptive Device)
Device
Lead sponsor
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Torrance, California
Source: ClinicalTrials.gov public record
Updated Aug 10, 2014 · Synced Sep 3, 2026, 9:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A RCT of Ultrasound Guided IUD Insertion

NCT03493815
View directory record Official record
Conditions
IUD Not Visible
Interventions
Transabdominal Ultrasound Guided IUD Insertion, Traditional Blind IUD Insertion
Procedure
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 20, 2020 · Synced Sep 3, 2026, 9:43 PM EDT
Completed Phase 4 Interventional

Immediate Versus Delayed Intrauterine Device (IUD) Insertion Following First Trimester Suction Aspiration Procedures

NCT00562276
View directory record Official record
Conditions
Contraception
Interventions
Immediate IUD insertion
Procedure
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older · Female only
Enrollment
578 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
3
States / cities
Atlanta, Georgia • Albuquerque, New Mexico • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 13, 2012 · Synced Sep 3, 2026, 9:43 PM EDT
Completed No phase listed Observational

Occurrence and Trend of Pregnancies Growing Outside the Womb (Ectopic Pregnancy) 2009-2018. A Study on a Defined Group of Persons

NCT03670784
View directory record Official record
Conditions
Pregnancy, Ectopic
Interventions
No intervention
Other
Lead sponsor
Bayer
Industry
Eligibility
15 Years to 44 Years · Female only
Enrollment
3,922,877 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 4, 2022 · Synced Sep 3, 2026, 9:43 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

LNG-IUS at 2 Weeks Postpartum

NCT02121067
View directory record Official record
Conditions
Contraception, Malposition of Intrauterine Contraceptive Device
Interventions
Levonorgestrel Intrauterine System (LNG-IUS)
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 23, 2017 · Synced Sep 3, 2026, 9:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Naproxen for Pain Control With Intrauterine Device Insertion

NCT02388191
View directory record Official record
Conditions
Contraception
Interventions
Naproxen sodium, Placebo tablet
Drug · Other
Lead sponsor
Planned Parenthood League of Massachusetts
Other
Eligibility
18 Years and older · Female only
Enrollment
119 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 21, 2017 · Synced Sep 3, 2026, 9:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of Immune Cell Changes in the Genital Tract 2 Months After Initiation of an IUD for Contraception

NCT01240811
View directory record Official record
Conditions
Genital Tract Mucosal Immunity, Genital Tract Microflora
Interventions
IUD placement, Levonorgestrel IUD, Copper T380A IUD
Drug
Lead sponsor
Sharon Achilles
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 25, 2017 · Synced Sep 3, 2026, 9:43 PM EDT
Enrolling by invitation Phase 2 Interventional Accepts healthy volunteers

Oral Ketorolac for IUD Pain Reduction

NCT06853327
View directory record Official record
Conditions
IUD Insertion Pain
Interventions
Ketorolac, Placebo
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Hillsborough, North Carolina
Source: ClinicalTrials.gov public record
Updated May 29, 2025 · Synced Sep 3, 2026, 9:43 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

A Randomized Controlled Trial of No Strings Intrauterine Device (IUD) Removal Techniques

NCT05702242
View directory record Official record
Conditions
IUD Threads Not Visible, IUD Removal Complication
Interventions
IUD removal with no visible strings, Alligator forceps, Manual Vacuum Aspirator
Procedure · Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 30, 2024 · Synced Sep 3, 2026, 9:43 PM EDT
Terminated Not applicable Interventional Results available

Immediate Postplacental IUD Insertion

NCT02169869
View directory record Official record
Conditions
Contraception
Interventions
Mirena, Paragard
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 30, 2019 · Synced Sep 3, 2026, 9:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Use of Misoprostol for Intrauterine Device (IUD) Insertion in Nulliparous Women

NCT01001897
View directory record Official record
Conditions
Contraception
Interventions
Misoprostol, Placebo
Drug
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
2
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 13, 2012 · Synced Sep 3, 2026, 9:43 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Stress Hormones and IUDs

NCT03499379
View directory record Official record
Conditions
Contraception, Mood Change
Interventions
Mirena, Paraguard
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 39 Years · Female only
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 6, 2020 · Synced Sep 3, 2026, 9:43 PM EDT
Completed Not applicable Interventional

Effect of an Intrauterine Contraceptive Device (IUD) in HIV Infected Women

NCT00096694
View directory record Official record
Conditions
HIV Infections
Interventions
Levonorgestrel-releasing intrauterine device (IUD)
Device
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years and older · Female only
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2005
U.S. locations
8
States / cities
Los Angeles, California • Baltimore, Maryland • Fall River, Massachusetts + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2021 · Synced Sep 3, 2026, 9:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Early vs. Interval Postpartum IUD Insertion

NCT03462758
View directory record Official record
Conditions
Contraception
Interventions
IUD
Device
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older · Female only
Enrollment
404 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
4
States / cities
La Jolla, California • San Diego, California • Chicago, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 12, 2023 · Synced Sep 3, 2026, 9:43 PM EDT
Terminated Not applicable Interventional

Intrauterine Device (IUD) Self Removal

NCT05191238
View directory record Official record
Conditions
IUD Removal
Interventions
IUD self-removal education
Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 21, 2023 · Synced Sep 3, 2026, 9:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Innovative Model of Patient-Centered ConTraception

NCT02364037
View directory record Official record
Conditions
Contraception, Unintended Pregnancy
Interventions
CHOICE Project Structured Contraceptive Counseling, Contraceptive Education Session, Cost Support for IUDs and implants
Behavioral · Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
14 Years to 45 Years · Female only
Enrollment
1,008 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
3
States / cities
St Louis, Missouri • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 1, 2020 · Synced Sep 3, 2026, 9:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Tolerability and Satisfaction With Evie

NCT01969812
View directory record Official record
Conditions
Infertility
Interventions
Evie Slow-release Insemination Device, Traditional Intrauterine Insemination
Device · Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 21, 2022 · Synced Sep 3, 2026, 9:43 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Misoprostol With Intrauterine Device Insertion

NCT00613366
View directory record Official record
Conditions
Contraception
Interventions
Misoprostol, Magnesium Oxide
Drug · Dietary Supplement
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
2
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 14, 2013 · Synced Sep 3, 2026, 9:43 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Quantification of Immune Cells in Women Using Contraception (CHIC II)

NCT01873170
View directory record Official record
Conditions
HIV, Immune Cells (Mucosal and Systemic), Contraception
Interventions
levonorgestrel exposure, DMPA exposure, etonogestrel exposure, IUD insertion, subdermal contraceptive implant insertion
Drug · Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 34 Years · Female only
Enrollment
326 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 26, 2021 · Synced Sep 3, 2026, 9:43 PM EDT