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ClinicalTrials.gov public records Last synced Sep 11, 2026, 4:56 PM EDT

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Showing 1–24 of 37 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Intubated Patients Clear all
Completed Not applicable Interventional

A Pilot Study Swiftsure

NCT05578599
View directory record Official record
Conditions
Ventilated Patients
Interventions
Swiftsure CCS device
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 22, 2023 · Synced Sep 11, 2026, 4:56 PM EDT
Recruiting Phase 2 Interventional

Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection

NCT06999603
View directory record Official record
Conditions
Viral Pneumonia
Interventions
SNG001, Placebo
Drug
Lead sponsor
Synairgen Research Ltd.
Industry
Eligibility
18 Years and older
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
22
States / cities
Sacramento, California • Torrance, California • Naples, Florida + 19 more
Source: ClinicalTrials.gov public record
Updated Dec 30, 2025 · Synced Sep 11, 2026, 4:56 PM EDT
Terminated No phase listed Observational

Intubated ICU Patients

NCT02171091
View directory record Official record
Conditions
Patients Requiring Endotracheal Intubation
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 85 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 14, 2018 · Synced Sep 11, 2026, 4:56 PM EDT
Terminated Early Phase 1 Interventional

Convalescent Plasma in ICU Patients With COVID-19-induced Respiratory Failure

NCT04353206
View directory record Official record
Conditions
Covid-19, Sars-CoV2
Interventions
Multiple Doses of Anti-SARS-CoV-2 convalescent plasma
Biological
Lead sponsor
Noah Merin
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
2
States / cities
Los Angeles, California • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 7, 2021 · Synced Sep 11, 2026, 4:56 PM EDT
Completed Phase 3 Interventional

Oral Care to Reduce Mouth and Throat Infections in Critically Ill Patients

NCT00078663
View directory record Official record
Conditions
Critical Illness
Interventions
Oral Care
Behavioral
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
5
States / cities
Washington D.C., District of Columbia • Bethesda, Maryland • Fairfax, Virginia + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 11, 2026, 4:56 PM EDT
Completed Not applicable Interventional

Music Therapy With Intubated and Sedated Pediatric Patients

NCT03629145
View directory record Official record
Conditions
Respiratory Syncytial Virus Infections
Interventions
Live Music Therapy, Recorded Music Therapy
Behavioral
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
Up to 2 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 25, 2019 · Synced Sep 11, 2026, 4:56 PM EDT
Completed No phase listed Observational

Airway IgA: Respiratory Tract IgA Levels in Critically Ill Intubated Patients

NCT00205309
View directory record Official record
Conditions
Intubation, Critically Ill
Interventions
Not listed
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2011
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 17, 2012 · Synced Sep 11, 2026, 4:56 PM EDT
Active, not recruiting Not applicable Interventional

Efficacy of A Novel RinSe Device to Reduce Oral Bacteria in Intubated IntEnsive CaRe Patients: a Pilot Study

NCT06193512
View directory record Official record
Conditions
Oral Bacterial Infection, Mechanical Ventilation Complication
Interventions
SwishKit + Oral care treatment as usual, Oral care treatment as usual
Device · Procedure
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Sep 11, 2026, 4:56 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of PEEP on TRJV in Mechanically Intubated Pediatric Patients

NCT06229886
View directory record Official record
Conditions
Tricuspid Regurgitation, Mechanical Ventilation Pressure High, Pediatric Respiratory Diseases
Interventions
Application of positive-end-expiratory pressure
Other
Lead sponsor
Northwell Health
Other
Eligibility
3 Months to 18 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Sep 25, 2024 · Synced Sep 11, 2026, 4:56 PM EDT
Completed No phase listed Observational

New Devices to Measure the Intracuff Pressure

NCT02202798
View directory record Official record
Conditions
Patients Intubated With a Cuffed Endotracheal Tube
Interventions
Syringe device
Device
Lead sponsor
Joseph D. Tobias
Other
Eligibility
Up to 18 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 3, 2015 · Synced Sep 11, 2026, 4:56 PM EDT
Not listed Not applicable Interventional

The Prognostic Value of Limited Transthoracic Echocardiogram (LTTE) During Trauma Resuscitation

NCT02218983
View directory record Official record
Conditions
Patients Who Are in Shock and Intubated in the Trauma Bay (TB)
Interventions
Limited Transthoracic Echocardiogram (LTTE, SonoSite Ultrasound), Usual care
Device · Other
Lead sponsor
Riverside University Health System Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Moreno Valley, California
Source: ClinicalTrials.gov public record
Updated Apr 16, 2017 · Synced Sep 11, 2026, 4:56 PM EDT
Completed Phase 3 Interventional Results available

Inhaled Amikacin Solution BAY41-6551 as Adjunctive Therapy in the Treatment of Gram-Negative Pneumonia

NCT01799993
View directory record Official record
Conditions
Pneumonia, Bacterial
Interventions
Amikacin Inhalation Solution (BAY41-6551), Aerosolized Placebo
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older
Enrollment
725 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
32
States / cities
Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 27 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2018 · Synced Sep 11, 2026, 4:56 PM EDT
Terminated Phase 1 Interventional

A Clinical Safety Study on AT-100 in Treating Adults With Severe COVID-19 Infection or Severed Community Acquired Pneumonia

NCT04659122
View directory record Official record
Conditions
COVID-19, Undefined
Interventions
AT-100
Biological
Lead sponsor
Airway Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 13, 2023 · Synced Sep 11, 2026, 4:56 PM EDT
Withdrawn Not applicable Interventional

Evaluation of Leak-Free Bronchoscope Adapter to Limit Ventilated Air Volume Loss During Bronchoscopy

NCT06310577
View directory record Official record
Conditions
Pulmonary Disease
Interventions
Leak-free bronchoscope adapter
Device
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 29, 2025 · Synced Sep 11, 2026, 4:56 PM EDT
Completed No phase listed Observational

Prehospital Ventilator-Associated Pneumonia Prevention Trial

NCT01902446
View directory record Official record
Conditions
Wounds and Injuries, Respiratory Failure, Pneumonia, Ventilator-Associated
Interventions
Chlorhexidine gluconate
Drug
Lead sponsor
Nicholas M Mohr
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 8, 2017 · Synced Sep 11, 2026, 4:56 PM EDT
Completed Phase 4 Interventional

A Safety and Efficacy Study of Dexmedetomidine in ICU Patients Requiring Continuous Sedation

NCT00216190
View directory record Official record
Conditions
Mechanically Ventilated and Intubated Subjects
Interventions
Dexmedetomidine HCL Injection, Midazolam Injection
Drug
Lead sponsor
Hospira, now a wholly owned subsidiary of Pfizer
Industry
Eligibility
18 Years and older
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
78
States / cities
Birmingham, Alabama • Chandler, Arizona • Phoenix, Arizona + 75 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2015 · Synced Sep 11, 2026, 4:56 PM EDT
Withdrawn Not applicable Interventional

The HEALiX™ Intubated Patient (IP) Pilot Study

NCT04759066
View directory record Official record
Conditions
Device Ineffective, Safety Issues
Interventions
HEALiX
Device
Lead sponsor
Lancaster General Hospital
Other
Eligibility
18 Years to 89 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Lancaster, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 2, 2022 · Synced Sep 11, 2026, 4:56 PM EDT
Withdrawn No phase listed Observational

Utility of Empiric Antibiotics for Non-intubated Novel Coronavirus Diseases 2019 Patients

NCT04674410
View directory record Official record
Conditions
Covid19, Coronavirus Infection, Pneumonia
Interventions
Antibiotic
Drug
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 21, 2024 · Synced Sep 11, 2026, 4:56 PM EDT
Completed No phase listed Observational

Accuracy of Using the CPAP Technique to Eliminate Air Leak and Prevent Excessive Endotracheal Tube Cuff Pressures

NCT01384318
View directory record Official record
Conditions
Surgical Patients Intubated With Cuffed ETT
Interventions
Manometer
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Up to 17 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 29, 2012 · Synced Sep 11, 2026, 4:56 PM EDT
Completed Not applicable Interventional

Effects of Oral Care in the Neuroscience ICU

NCT00518752
View directory record Official record
Conditions
Ventilator Associated Pneumonia, Oral Hygiene
Interventions
Standard Oral Care, Comprehensive Oral Care
Procedure
Lead sponsor
St. Joseph's Hospital and Medical Center, Phoenix
Other
Eligibility
18 Years and older
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 15, 2013 · Synced Sep 11, 2026, 4:56 PM EDT
Completed Phase 2 Interventional

Safety, Tolerability and Pharmacokinetics of Aerosolized Amikacin in Intubated and Mechanically-ventilated Patients With Nosocomial Pneumonia

NCT01021436
View directory record Official record
Conditions
Pneumonia
Interventions
Amikacin inhalation solution (BAY41-6551)
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
4
States / cities
Birminghan, Alabama • Cincinnati, Ohio • Memphis, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2016 · Synced Sep 11, 2026, 4:56 PM EDT
Completed No phase listed Observational Results available

Gastric Ultrasound in Tube Fed Intubated Patients

NCT04612348
View directory record Official record
Conditions
Critical Illness
Interventions
Ultrasound
Diagnostic Test
Lead sponsor
Joseph D. Tobias
Other
Eligibility
Up to 18 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 11, 2026, 4:56 PM EDT
Completed Not applicable Interventional

Trial of Continuous Versus Interrupted Feeding for Intubated Intensive Care Unit Patients

NCT01383980
View directory record Official record
Conditions
Malnutrition
Interventions
Continuous Tube Feedings
Dietary Supplement
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 18, 2019 · Synced Sep 11, 2026, 4:56 PM EDT
Withdrawn Phase 1 Interventional

Validation of Aspiration Markers in Intubated Patients

NCT02598713
View directory record Official record
Conditions
Pneumonia, Aspiration
Interventions
Aspiration Marker
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Sep 11, 2026, 4:56 PM EDT