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Conditions: Gout
Interventions: lesinurad 400 mg, naproxen 250 mg, indomethacin 25 mg; Drug
Lead sponsor: Ardea Biosciences, Inc.; Industry
Eligibility: 18 Years to 55 Years · Male only
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013
U.S. locations: 1
States / cities: Kalamazoo, Michigan

Conditions: Osteoarthritis
Interventions: Total knee; Procedure
Lead sponsor: Heekin Orthopedic Research Institute; Other
Eligibility: 21 Years to 80 Years
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Joint Infection
Interventions: No-Rinse Solution (NS), Saline irrigation; Other
Lead sponsor: Northwell Health; Other
Eligibility: Not listed
Enrollment: 936 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 3
States / cities: Manhasset, New York • New Hyde Park, New York • New York, New York

Conditions: Developmental Dysplasia of the Hip
Interventions: Delta Dry® Waterproof Pantaloon, Cotton Padding; Other
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 0 Years to 5 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Uncontrolled Gout, Chronic Gout
Interventions: Pegloticase, Methotrexate (MTX); Biological · Drug
Lead sponsor: Amgen; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 12
States / cities: Anchorage, Alaska • Glendale, Arizona • San Leandro, California + 9 more

Conditions: Joint Infection
Interventions: PLG0206; Drug
Lead sponsor: Peptilogics; Industry
Eligibility: 18 Years to 79 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 12
States / cities: Palo Alto, California • Sarasota, Florida • Baltimore, Maryland + 8 more

Conditions: Osteoarthritis (OA) of the Knee
Interventions: Preoperative Methadone, Preoperative Oxycodone; Drug
Lead sponsor: University of Louisville; Other
Eligibility: 21 Years to 89 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: Louisville, Kentucky

Conditions: Rheumatoid Arthritis
Interventions: Olokizumab, Placebo; Drug
Lead sponsor: R-Pharm International, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 368 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 50
States / cities: Phoenix, Arizona • Hot Springs, Arkansas • Covina, California + 44 more

Conditions: Total Joint Replacement Surgery
Interventions: SPARTA force plate; Device
Lead sponsor: Derek Amanatullah; Other
Eligibility: 18 Years to 99 Years
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Stanford, California

Conditions: Osteoarthritis, Knee
Interventions: Lidocaine Hydrochloride; Drug
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 45 Years and older
Enrollment: 55 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Temporomandibular Joint Disorders, Orofacial Pain
Interventions: Cognitive-Behavioral Treatment, Individualized Assessment and Treatment Program, Standard Conservative Care; Behavioral · Other
Lead sponsor: UConn Health; Other
Eligibility: 18 Years and older
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Farmington, Connecticut

Conditions: Pain, Chronic, Pain, Joint Pain, Musculoskeletal Pain
Interventions: Not listed
Lead sponsor: Stanford University; Other
Eligibility: 11 Years to 18 Years
Enrollment: 275 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 2
States / cities: Palo Alto, California • Cincinnati, Ohio

Conditions: Osteoarthritis
Interventions: SD-6010, Placebo; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 40 Years to 99 Years
Enrollment: 1,457 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 120
States / cities: Birmingham, Alabama • Peoria, Arizona • Phoenix, Arizona + 83 more

Conditions: Defect of Articular Cartilage, Osteochondral Lesion of Talus, Osteochondritis Dissecans
Interventions: DeNovo NT Natural Tissue Graft; Other
Lead sponsor: Zimmer Orthobiologics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 205 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2019
U.S. locations: 8
States / cities: Sacramento, California • Honolulu, Hawaii • Baltimore, Maryland + 5 more

Conditions: Arthralgia, Breast Cancer
Interventions: Cannabidiol (CBD); Drug
Lead sponsor: University of Michigan Rogel Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Rheumatoid Arthritis
Interventions: Non-Interventional; Other
Lead sponsor: Bristol-Myers Squibb; Industry
Eligibility: 18 Years and older
Enrollment: 1,132 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Princeton, New Jersey

Conditions: Osteoarthritis, Knee
Interventions: Health coach, Remote Incentive Program; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 40 Years to 90 Years
Enrollment: 254 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 5
States / cities: Birmingham, Alabama • Omaha, Nebraska • Portland, Oregon + 2 more

Conditions: Arthritis, Rheumatoid
Interventions: CP-690,550; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years and older
Enrollment: 4,488 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2017
U.S. locations: 147
States / cities: Birmingham, Alabama • Huntsville, Alabama • Gilbert, Arizona + 116 more

Conditions: Spondylitis, Ankylosing
Interventions: Secukinumab, Placebo secukinumab; Drug
Lead sponsor: Novartis Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 226 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 14
States / cities: Mobile, Alabama • Mesa, Arizona • Peoria, Arizona + 11 more

Conditions: Pain Dysfunction, Sleep Disturbance, Osteoarthritis
Interventions: Lifestyles A, Lifestyles B, Lifestyles C; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 60 Years and older
Enrollment: 367 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 2
States / cities: Seattle, Washington

Conditions: Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout, Crohn Disease, Juvenile Idiopathic Arthritis, Lupus Erythematosus, Myositis, Osteoarthritis, Osteoporosis, Psoriasis, Psoriatic Arthritis, Scleroderma, Dermatomyositis, Inflammatory Bowel Diseases, Polymyositis, Axial Spondyloarthritis, Diffuse Idiopathic Skeletal Hyperostosis, Polymyalgia Rheumatica, Giant Cell Arteritis, Temporal Arteritis, Wegener, Relapsing Polychondritis, Undifferentiated Connective Tissue Disease, Spinal Cord Injuries, Alzheimer Disease, Amyotrophic Lateral Sclerosis, Ataxia, Bell Palsy, Brain Tumor, Cerebral Aneurysm, Epilepsy, Guillain-Barre Syndrome, Headache, Head Injury, Hydrocephalus, Lumbar Disc Disease, Meningitis, Multiple Sclerosis, Muscular Dystrophy, Neurocutaneous Syndromes, Parkinson Disease, Stroke, Cluster Headache, Tension-Type Headache, Chronic Obstructive Pulmonary Disease, Asthma, Lung Cancer, Cystic Fibrosis, Sleep Apnea, Eczema, Alopecia, Chronic Inflammation, Unstable Angina, Heart Attack, Heart Failure, Arrythmia, Valve Heart Disease, High Blood Pressure, Congenital Heart Disease, Peripheral Arterial Disease, Diabetes, Chronic Liver Disease, Obesity
Interventions: Not listed
Lead sponsor: Global Healthy Living Foundation; Other
Eligibility: 19 Years and older
Enrollment: 40,000 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2025
U.S. locations: 1
States / cities: Upper Nyack, New York

Conditions: Rheumatoid Arthritis, Osteoarthritis
Interventions: Arthritis Self-Management Program, SMART Program; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 1,200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1996 – 2001
U.S. locations: 4
States / cities: Palo Alto, California • Wichita, Kansas • Pittsburgh, Pennsylvania + 1 more

Conditions: CNS Malignancies, Medulloblastoma Recurrent, ATRT Recurrent, Pineoblastoma, Embryonal Neoplasm, Ependymoma Recurrent, High Grade Gliomas
Interventions: SGT-53, hypofractionated radiotherapy with immunotherapy, Nivolumab; Drug · Radiation
Lead sponsor: Children's National Research Institute; Other
Eligibility: 3 Years to 21 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Osteoarthritis, Insomnia
Interventions: Placebo, Eszopiclone; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 64 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2013
U.S. locations: 1
States / cities: Baltimore, Maryland

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NSAID Drug Interaction Study

Anterior Referencing Versus Posterior Referencing in Minimally Invasive Total Knee Arthroplasty

Rate of Total Joint Infection 90-day After Surgery Following Irrigation With Next Science No-Rinse Solution vs SOC Alone

Effectiveness of Cotton vs. Waterproof Cast Padding

A Phase 4, Open-label Study of KRYSTEXXA® (Pegloticase) Co-administered With Methotrexate (MTX) in Patients With Uncontrolled Gout (FORWARD OL)

Study in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Occurring After Total Knee Arthroplasty (TKA)

Postoperative Pain and Analgesic Requirements After Preoperative Methadone for Primary TKA

Evaluation of the Efficacy and Safety of Two Dosing Regimens of Olokizumab (OKZ), Compared to Placebo, in Subjects With Rheumatoid Arthritis (RA) Who Were Taking an Existing Medication Called a Tumour Necrosis Factor Alpha Inhibitor But Had Active Disease

A Rehabilitation Tool to Determine Patient's Stay in Hospital After Joint Replacement

Effect of Knee Pain on Walking Biomechanics

Individualized Assessment and Treatment for TMD

SPRINT: Signature for Pain Recovery IN Teens

A Long-Term, Placebo-Controlled X-Ray Study Investigating the Safety and Efficacy of SD-6010 in Subjects With Osteoarthritis of the Knee

DeNovo NT Ankle LDC Study

Cannabidiol (CBD) for Treatment of Aromatase Inhibitor-Associated Arthralgias

A Study to Determine the Risk of Cancer in Rheumatoid Arthritis (RA) Patients Who Use Abatacept and Other Biologic Agents

Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans

Long-Term Effectiveness And Safety Of CP-690,550 For The Treatment Of Rheumatoid Arthritis

16-week Efficacy and 3-year Safety, Tolerability and Efficacy of Secukinumab in Active Ankylosing Spondylitis Patients

Cognitive Behavioral Therapy for Arthritis Pain and Insomnia in Older Adults

PatientSpot Formerly Known as ArthritisPower

Patient Education in Rheumatoid Arthritis and Osteoarthritis

A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refractory CNS Malignancies.

Insomnia and Osteoarthritis Study