Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 13, 2026, 9:13 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 217–240 of 354 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Joint Replacement Clear all

Conditions: Arthroplasty, Replacement
Interventions: Investigational Arm: SMR Stemless Reverse, Control Arm: SMR Reverse Shoulder System; Device
Lead sponsor: Limacorporate S.p.a; Industry
Eligibility: 22 Years and older
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2028
U.S. locations: 13
States / cities: Los Angeles, California • Denver, Colorado • Boca Raton, Florida + 9 more

Conditions: Osteoarthritis of the Knee
Interventions: Blood Draw, Joint Aspirate Harvest; Procedure
Lead sponsor: Scuderi, Gaetano J., M.D.; Other
Eligibility: 19 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Knee Total Joint Replacement, Hip Total Joint Replacement
Interventions: Education on disposal of opioids; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 1
States / cities: Scottsdale, Arizona

Conditions: Osteoarthritis
Interventions: Not listed
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 45 Years and older
Enrollment: 248 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2019
U.S. locations: 1
States / cities: Chestnut Hill, Massachusetts

Conditions: Radial Head Fractures
Interventions: DePuy Synthes Radial Head Replacement System; Device
Lead sponsor: DePuy Synthes Products, Inc.; Industry
Eligibility: 22 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2030
U.S. locations: 3
States / cities: Cleveland, Ohio • Eugene, Oregon • Falls Church, Virginia

Conditions: Knee Injuries, Knee Osteoarthritis, Knee Arthritis
Interventions: B-FREE; Other
Lead sponsor: Michigan Technological University; Other
Eligibility: 40 Years to 75 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2027
U.S. locations: 1
States / cities: Houghton, Michigan

Conditions: Osteoarthritis, Arthroplasty, Replacement, Knee
Interventions: Patient support sessions, Treatment as usual; Behavioral
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 21 Years and older
Enrollment: 196 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2012
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Osteoarthritis,Knee
Interventions: ConforMIS iTotal® Knee Replacement; Device
Lead sponsor: Restor3D; Industry
Eligibility: 19 Years and older
Enrollment: 235 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Atlantis, Florida

Conditions: Hip Arthropathy, Knee Arthropathy, Vitamin D Deficiency
Interventions: Vitamin D3; Dietary Supplement
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 900 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Arthritis
Interventions: Total knee arthroplasty; Procedure
Lead sponsor: Heekin Orthopedic Research Institute; Other
Eligibility: 21 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Jacksonville, Florida

Conditions: Arthritis
Interventions: Live Music Therapy, Recorded Music Therapy, Control; Other
Lead sponsor: April Armstrong; Other
Eligibility: 18 Years and older
Enrollment: 121 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Arthroplasty, Replacement, Knee
Interventions: Radiofrequency Ablation (RFA), Simulated Radiofrequency Ablation (RFA); Procedure
Lead sponsor: Northwestern University; Other
Eligibility: 30 Years to 80 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Osteoarthritis, Knee
Interventions: Exercise; Behavioral
Lead sponsor: Helen Hayes Hospital; Other
Eligibility: 60 Years to 89 Years
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: West Haverstraw, New York

Conditions: Knee Osteoarthritis, Total Knee Replacement
Interventions: Telephonic Active Coaching (Motivational Interviewing) + Financial Incentives, Wrist based activity tracker wear, Basic Study Activities; Behavioral · Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 40 Years to 85 Years
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 5
States / cities: Chicago, Illinois • Kansas City, Kansas • Boston, Massachusetts + 2 more

Conditions: Osteoarthritis, Inflammatory Arthritis
Interventions: TSR - traditional subscapularis release, TSR - rotator cuff sparing; Procedure
Lead sponsor: NYU Langone Health; Other
Eligibility: 21 Years and older
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Arthropathy of Knee Joint, Arthropathy of Hip Joint
Interventions: personalized prehabilitation; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 55 Years and older
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2029
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Knee Arthroplasty
Interventions: Total Knee Arthroplasty, MAKO® Robot Assisted Medial Knee Arthroplasty, RESTORIS Multicompartmental Knee System, Depuy Knee Replacement System, Stryker® Knee Replacement System; Procedure · Device
Lead sponsor: Northwest Surgical Specialists, Vancouver; Other
Eligibility: 21 Years to 80 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2023
U.S. locations: 1
States / cities: Vancouver, Washington

Conditions: Non-inflammatory Degenerative Joint Disease
Interventions: ASR™-XL Modular Acetabular Cup System, Pinnacle™ acetabular shell; Device
Lead sponsor: DePuy Orthopaedics; Industry
Eligibility: 20 Years to 75 Years
Enrollment: 265 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 8
States / cities: Rancho Mirage, California • Cumming, Georgia • Morton Grove, Illinois + 5 more

Conditions: Osteoarthritis
Interventions: Evaluation of Augmented Reality technology in TKA compared to standard TKA; Other
Lead sponsor: Foundation for Orthopaedic Research and Education; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Knee Pain Arthritis
Interventions: periarticular bupivicaine and liposomal bupivicaine; Drug
Lead sponsor: OrthoCarolina Research Institute, Inc.; Other
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2017
U.S. locations: 4
States / cities: Charlotte, North Carolina

Conditions: Hypovitaminosis D
Interventions: Cholecalciferol, Placebo; Dietary Supplement
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 100 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Joint Disease
Interventions: total hip arthroplasty implant; Device
Lead sponsor: MicroPort Orthopedics Inc.; Industry
Eligibility: 21 Years to 80 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Spokane, Washington

Conditions: Osteoarthritis of Knee
Interventions: Medacta GMK Sphere; Device
Lead sponsor: Northwestern University; Other
Eligibility: 18 Years to 90 Years
Enrollment: 112 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Knee Arthroplasty
Interventions: Non-MAKO® Robot Assisted Total Knee Arthroplasty, MAKO® Robot Assisted Medial Knee Arthroplasty, MAKO® Robot Assisted Medial and PF Knee Arthroplasty, RESTORIS Multicompartmental Knee System, Depuy Knee Replacement System, Stryker® Knee Replacement System; Procedure · Device
Lead sponsor: Northwest Surgical Specialists, Vancouver; Other
Eligibility: 21 Years and older
Enrollment: 316 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2018
U.S. locations: 1
States / cities: Vancouver, Washington

Search by objective public record fields.

SMR Stemless Reverse vs SMR Reverse Shoulder System

Serum and Synovium Protease Inhibitor Levels in Primary and Secondary Osteoarthritic Joints

Increasing Awareness of Opioid Disposal in the Orthopedic Patient Population

Prediction of Outcomes Following Total Knee Replacement

A Study of Participants Undergoing Radial Head Replacement Using the DePuy Synthes Radial Head Replacement System for Partial Replacement of the Elbow Joint

Blood-Flow Restriction Exercise Following a Knee Replacement

Perioperative Intervention to Improve Post-TKR Support and Function

Costs and Benefits of ConforMIS iTotal® Knee Replacement System Versus Standard Total Knee

Effect of Vitamin D Status and Repletion on Postoperative Total Joint Arthroplasty Complications

Effect of Preop Nutritional Status on Outcomes of Staged Bilateral Total Knee Arthroplasty

The Effect of Music Therapy Intervention on Pain and Anxiety in Adult Patients Undergoing Total Shoulder Arthroplasty

Does Radiofrequency Ablation of the Articular Nerves of the Knee Prior to Total Knee Replacement Improve Pain Outcomes

A Comparative Analysis of Two Types of Exercise on Outcomes Following Total Knee Arthroplasty

Knee Arthroplasty Activity Trial

Rotator Cuff Sparing Total Arthroplasty

A Personalized Prehabilitation Intervention In Elective Joint Replacement Surgery

Clinical and Economic Comparison of Robot Assisted Versus Manual Knee Replacement

Multi-Center Comparative Trial of the ASR™-XL Acetabular Cup System vs. the Pinnacle™ Metal- on- Metal Total Hip System

ARVIS TKA vs Conventional TKA

Serum Levels of Bupivacaine in Autotransfusion Drains Following Total Joint Arthroplasty

Vitamin D Status in Lower Extremity Joint Replacement Surgery Patients

Evaluation of Bone Mineral Density Changes After Total Hip Replacement: A Two-Year Clinical and DXA Analysis

Total Knee Replacement Component Alignment Using Manual Versus Custom Instrumentation

Clinical Outcomes of Knee Replacement