Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 14, 2026, 12:02 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 265–288 of 354 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Joint Replacement Clear all

Conditions: Knee Osteoarthritis, Knee Replacement
Interventions: Not listed
Lead sponsor: University of Massachusetts, Worcester; Other
Eligibility: 18 Years to 99 Years
Enrollment: 161 participants
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Worcester, Massachusetts

Conditions: Osteoarthritis of Knee, Edema, Wounds and Injuries
Interventions: ODIN1, Standard Care, Diagnostic Device Testing; Device · Other
Lead sponsor: Bioelectric Research Corporation; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016
U.S. locations: 2
States / cities: Las Vegas, Nevada

Conditions: Arthroplasty
Interventions: Biomet TMJ Replacement System; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 18 Years and older
Enrollment: 93 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 4
States / cities: Indianapolis, Indiana • West Bloomfield, Michigan • Philadelphia, Pennsylvania + 1 more

Conditions: Osteoarthritis, Pain
Interventions: Placebo, Fulranumab 1 mg, Fulranumab 3 mg; Drug
Lead sponsor: Janssen Research & Development, LLC; Industry
Eligibility: 18 Years to 99 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 7
States / cities: El Cajon, California • Sherman Oaks, California • Miami, Florida + 4 more

Conditions: Joint (Knee or Hip Replacement)
Interventions: Sleep banking; Behavioral
Lead sponsor: Defense and Veterans Center for Integrative Pain Management; Other
Eligibility: 18 Years to 74 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: San Diego, California

Conditions: Osteoarthritis
Interventions: Off the Shelf Total Knee Replacement, ConforMIS iTotal Knee Replacement; Device
Lead sponsor: Restor3D; Industry
Eligibility: 18 Years and older
Enrollment: 215 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2022
U.S. locations: 8
States / cities: La Jolla, California • San Diego, California • Parker, Colorado + 5 more

Conditions: Osteoarthritis, Sarcopenia
Interventions: Total knee replacement surgery; Procedure
Lead sponsor: University of Florida; Other
Eligibility: 60 Years and older
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Avascular Necrosis, Acute Fracture
Interventions: non-coated femoral hip stem, coated femoral hip stem; Device
Lead sponsor: DePuy Orthopaedics; Industry
Eligibility: Up to 75 Years
Enrollment: 245 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2009
U.S. locations: 1
States / cities: Warsaw, Indiana

Conditions: Knee Osteoarthritis
Interventions: DA/MI Intervention, an educational program (an NIH-developed booklet); Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 50 Years and older
Enrollment: 493 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2014
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Osteo Arthritis Shoulders, Traumatic Arthritis, Rheumatoid Arthritis
Interventions: Integra Titan Modular Shoulder System 2.5; Device
Lead sponsor: Smith & Nephew, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 7
States / cities: Birmingham, Alabama • Columbia, Maryland • Starkville, Mississippi + 3 more

Conditions: Osteoarthritis of Glenohumeral Joint
Interventions: Bigliani/Flatow Shoulder System; Device
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 207 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Osteoarthritis, Knee
Interventions: TKA surgery with modular polished tibial baseplate/XLK design, TKA surgery with the nonmodular APT/GVF design, P.F.C.® Sigma Knee System; Procedure · Device
Lead sponsor: Minneapolis Veterans Affairs Medical Center; Federal
Eligibility: 60 Years to 85 Years
Enrollment: 400 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2013
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Osteoarthritis
Interventions: Not listed
Lead sponsor: Anderson Orthopaedic Research Institute; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: Alexandria, Virginia

Conditions: Hip Osteoarthritis
Interventions: Not listed
Lead sponsor: Anne Arundel Health System Research Institute; Other
Eligibility: 40 Years to 90 Years
Healthy volunteers: Healthy volunteers not accepted
U.S. locations: 1
States / cities: Annapolis, Maryland

Conditions: Arthritis, Rheumatoid
Interventions: Not listed
Lead sponsor: Stryker Trauma and Extremities; Industry
Eligibility: 21 Years and older
Enrollment: 155 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2023
U.S. locations: 9
States / cities: Rancho Mirage, California • Fort Collins, Colorado • Libertyville, Illinois + 6 more

Conditions: Pain Management, Opioid Consumption
Interventions: Placebo, Oxycodone 5 mg, Multimodal Non-Opioid Analgesia; Drug · Other
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Osteoarthritis of the Knee
Interventions: Stryker Triathlon Tritanium primary knee; Device
Lead sponsor: Scott Sporer; Other
Eligibility: 18 Years to 80 Years
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2015
U.S. locations: 1
States / cities: Winfield, Illinois

Conditions: Osteoarthritis, Knee Infection, Prosthetic Joint Infection, Complications; Arthroplasty, Infection or Inflammation, Complications; Arthroplasty
Interventions: Static Spacer, Articulating Spacer; Procedure
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years to 100 Years
Enrollment: 68 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2020
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Osteoarthritis of the Knee
Interventions: Total Knee Arthroplasty; Device
Lead sponsor: Tufts Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2015
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Knee Osteoarthritis, Arthroplasty Complications
Interventions: Treadmill-based perturbation training, Education Control; Behavioral
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years and older
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Osteoarthritis, Knee, Arthritis, Rheumatoid
Interventions: total knee arthroplasty; Device
Lead sponsor: DePuy Orthopaedics; Industry
Eligibility: Up to 80 Years
Enrollment: 938 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2013
U.S. locations: 9
States / cities: Mobile, Alabama • Berkley, California • Fort Collins, Colorado + 6 more

Conditions: Osteoarthritis, Pain
Interventions: Placebo, Fulranumab 1 mg, Fulranumab 3 mg; Drug
Lead sponsor: Janssen Research & Development, LLC; Industry
Eligibility: 18 Years to 99 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 26
States / cities: Phoenix, Arizona • Costa Mesa, California • Laguna Hills, California + 23 more

Conditions: Osteoarthritis, Post-Traumatic Arthritis, Rheumatoid Arthritis
Interventions: Scandinavian Total Ankle Replacement (STAR); Device
Lead sponsor: Link America, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2001
U.S. locations: 5
States / cities: Jacksonville, Florida • Iowa City, Iowa • Kansas City, Kansas + 2 more

Conditions: Osteoarthritis
Interventions: Experimental: LRU Pillow, Control Group; Other
Lead sponsor: Newton-Wellesley Hospital; Other
Eligibility: 30 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Newton, Massachusetts

Search by objective public record fields.

Physical Therapy Components for Maximum TKR Outcome

Microcurrent Stimulation Reduces Post-Operative Swelling and Healing Time Following Knee Replacement Surgery

Total Temporomandibular Joint Replacement System Post Approval Study

Study of Efficacy, Safety of Fulranumab Monotherapy for OA of Hip or Knee, PAI3003

The Impact of Extending Sleep Before Joint-replacement Surgery on Post-surgical Pain

A Multicenter Study to Evaluate Functional Outcome After Knee Replacement

The Strong Brain Study

Clinical Study Comparing Two Implant Surface Finishes in Patients Undergoing Cementless Total Hip Replacement

Race and Preference for Knee Replacement: A Patient-Centered Intervention

Clinical Evaluation of the Integra® Titan™ Modular Shoulder System Generation 2.5 for Primary Shoulder Joint Replacement

Columbia Shoulder Study (CSS)

Comparison of a Metal Backed Fixed-Bearing Tibial Baseplate and an All-Polyethylene Tibia in Total Knee Arthroplasty

A Comparison of Wear Among Mobile and Fixed Bearing Knee Replacements

Hip Replacement in a High Volume Community Hospital: Effect on Length of Stay and Hospital Cost

INFINITY™Total Ankle Replacement Follow-up

Opioid-Sparing Joint Replacement

A Prospective Radiostereometric Analysis (RSA) and Clinical Evaluation of the Triathlon Tritanium Total Knee Replacement

Articulating Versus Static Antibiotic Loaded Spacers for the Treatment of Prosthetic Knee Infection

Prospective Functional Outcome Study of the Knee

Treadmill Perturbation Training for Fall Prevention After Total Knee Replacement

Gamma Vacuum Foil (GVF) Versus Cross-linked Polyethylene in Total Knee Arthroplasty Study

Study of Efficacy, Safety of Fulranumab Monotherapy for OA of Hip or Knee, PAI3002

Study of the Scandinavian Total Ankle Replacement (STAR) for the Treatment of Bilateral Degenerative Ankle Disease

Use of the LRU Pillow in the Acute Setting Following Total Knee Arthroplasty