Search | Clinical Trials Finder

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ClinicalTrials.gov public records Last synced Nov 13, 2026, 7:43 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 97–120 of 354 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Joint Replacement Clear all

Conditions: Osteoarthritis, Acetaminophen, Arthroplasty, Hip Replacement
Interventions: Intravenous acetaminophen, Oral acetaminophen; Drug
Lead sponsor: Duke University; Other
Eligibility: 56 Years to 85 Years
Enrollment: 81 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Primary Arthrosis
Interventions: Scandinavian Total Ankle Replacement System (STAR Ankle); Device
Lead sponsor: Stryker Trauma and Extremities; Industry
Eligibility: 18 Years and older
Enrollment: 87 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2016
U.S. locations: 5
States / cities: Oakland, California • Temple Terrace, Florida • Boise, Idaho + 2 more

Conditions: Osteoarthritis, Knee
Interventions: Digital hand-held surgical navigation system, Conventional tibial extramedullary alignment system; Device
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: Not listed
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: New York, New York

Conditions: Arthritis
Interventions: Live Music Therapy, Recorded Music Therapy, Control; Other
Lead sponsor: April Armstrong; Other
Eligibility: 18 Years and older
Enrollment: 121 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Osteoarthritis, Hip
Interventions: OMNI Apex Modular™ Hip Device, OMNI Apex ARC™ Hip Device; Device
Lead sponsor: Spokane Joint Replacement Center; Other
Eligibility: 20 Years to 80 Years
Enrollment: 73 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2018
U.S. locations: 1
States / cities: Spokane, Washington

Conditions: Knee Osteoarthritis, Pain, Postoperative, Acupuncture
Interventions: Acupuncture, Peripheral Nerve Stimulator; Other · Device
Lead sponsor: Hospital for Special Surgery, New York; Other
Eligibility: 18 Years to 70 Years
Enrollment: 41 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Talus, Ankle Arthropathy
Interventions: Total Talus Replacement (TTR), Total Ankle Total Talus Replacement (TATTR), Total Ankle Total Talus Replacement + Subtalar Fusion (TATTR + STJ), Total Talus Replacement + Subtalar Fusion (TTR + STJ); Procedure
Lead sponsor: Restor3D; Industry
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 2
States / cities: Paducah, Kentucky • Bellevue, Ohio

Conditions: Knee Osteoarthritis, Knee Rheumatism
Interventions: Obturator nerve regional block, Adductor canal regional block, Saline; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years to 85 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Arthritis
Interventions: Reverse Shoulder Arthroplasty, Total Shoulder Arthroplasty; Device
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 70 Years to 95 Years
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Arthroplasty
Interventions: Biomet TMJ Replacement System; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 18 Years and older
Enrollment: 93 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2008
U.S. locations: 4
States / cities: Indianapolis, Indiana • West Bloomfield, Michigan • Philadelphia, Pennsylvania + 1 more

Conditions: Arthritis
Interventions: Exparel, Saline; Drug · Other
Lead sponsor: Maimonides Medical Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Joint Disease, Arthropathy
Interventions: Zipper surgical skin closure, Monocryl + Dermabond, Polyester mesh + Dermabond; Device · Other
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 160 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Arthroplasty, Replacement, Hip
Interventions: Accolade® TMZF® Hip Stem; Device
Lead sponsor: Stryker Orthopaedics; Industry
Eligibility: 18 Years to 90 Years
Enrollment: 241 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2014
U.S. locations: 11
States / cities: Newport Beach, California • San Diego, California • Boynton Beach, Florida + 8 more

Conditions: Knee Replacement Surgery, Osteoarthritis
Interventions: Standard of Care, FLOSEAL Hemostatic Matrix + Standard of care; Procedure · Drug
Lead sponsor: Baxter Healthcare Corporation; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 137 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 12
States / cities: Los Angeles, California • Redwood City, California • Englewood, Colorado + 8 more

Conditions: Arthroplasty, Replacement, Knee, Osteoarthritis, Knee
Interventions: Journey II posterior cruciate retaining total knee arthroplasty, Journey II posterior bi-cruciate retaining total knee arthroplasty; Device
Lead sponsor: The University of Tennessee, Knoxville; Other
Eligibility: 40 Years to 85 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 4
States / cities: Chattanooga, Tennessee • Knoxville, Tennessee

Conditions: Knee Osteoarthritis, Post-traumatic Osteoarthritis
Interventions: Unicompartmental Biologic Arthroplasty, Extensive Biologic Arthroplasty; Procedure
Lead sponsor: University of Missouri-Columbia; Other
Eligibility: 18 Years to 55 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2022
U.S. locations: 1
States / cities: Columbia, Missouri

Conditions: Degenerative Arthritis, Rheumatoid Arthritis, Post Traumatic Arthritis
Interventions: Zimmer Trabecular Metal Total Ankle System; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2027
U.S. locations: 5
States / cities: Sacramento, California • Grand Rapids, Michigan • Charlotte, North Carolina + 2 more

Conditions: Osteoarthritis, Knee, Osteoarthritis, Hip
Interventions: mymobility with Apple Watch; Other
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 18 Years and older
Enrollment: 6,559 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2025
U.S. locations: 26
States / cities: Fremont, California • Irvine, California • Redwood City, California + 23 more

Conditions: Osteoarthritis, Knee
Interventions: Liposomal bupivacaine, Standard of Care; Drug
Lead sponsor: OhioHealth; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Knee Osteoarthristis
Interventions: Cognitive-Behavioral Therapy for Insomnia, Bright Light therapy via the Re-Timer®, Negative Ion exposure via IonMi Device, Sleep / Knee Osteoarthritis Education; Behavioral · Device
Lead sponsor: Johns Hopkins University; Other
Eligibility: 60 Years and older
Enrollment: 252 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 2
States / cities: Baltimore, Maryland • Chestnut Hill, Massachusetts

Conditions: Osteoarthritis: Joint Replacement Surgery
Interventions: CLARIX FLO, Saline; Other
Lead sponsor: BioTissue Holdings, Inc; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 1
States / cities: Orange Park, Florida

Conditions: Osteo Arthritis Knee
Interventions: Cryoneurolysis (Iovera); Procedure
Lead sponsor: Fondren Orthopedic Group L.L.P.; Other
Eligibility: 18 Years to 90 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Knee Pain, Chronic Osteoarthritis, Avascular Necrosis of the Femoral Condyle, Moderate Varus, Valgus or Flexion Deformities, Rheumatoid Arthritis
Interventions: PERSONA Total Knee, Vanguard Total Knee, NexGen Total Knee; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 18 Years and older
Enrollment: 181 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2023
U.S. locations: 5
States / cities: Vail, Colorado • Westminster, Colorado • Springfield, Illinois + 2 more

Conditions: Osteoarthritis, Blood Loss, Surgical, Blood Loss, Postoperative
Interventions: Tranexamic Acid (Oral), Tranexamic Acid (Intravenous); Drug
Lead sponsor: The New England Baptist Hospital; Other
Eligibility: 18 Years and older
Enrollment: 118 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Search by objective public record fields.

Intravenous Versus Oral Acetaminophen in Primary Total Hip Arthroplasty

Post-Approval Study to Investigate the Long Term (8 Year) Survivorship of STAR Ankle Among Continued Access Study Patients

Conventional Alignment System Versus Surgical Navigation System in Total Knee Arthroplasty

The Effect of Music Therapy Intervention on Pain and Anxiety in Adult Patients Undergoing Total Shoulder Arthroplasty

Femoral Remodeling Following Total Hip Arthroplasty With OMNI Apex Modular™ and OMNI Apex ARC™ Stem Compared to Competitive Designs

Acupuncture for Low-Dose Opioid for TKA Replacement

Retrospective Evaluation of Clinical and Radiographic Outcomes Following Total Talus Replacement

Does Adding an Additional Numbing Medication Injection in the Thigh Help With Pain Control After Knee Replacement Surgery?

Total vs. Reverse Shoulder Replacement: Pain Relief Two Years After Surgery

Total Temporomandibular Joint Replacement System Post Approval Study

Evaluation Exparel Delivered in Knee Replacement

A Study Investigating the Efficacy of Various Wound Closure Devices in Reducing Postoperative Wound Complications

Accolade® TMZF® Hip Stem Outcomes Study

Efficacy and Safety of FLOSEAL for Hemostasis in Total Knee Arthroplasty

Kinematics in Posterior Cruciate Retaining and Bi-Cruciate Retaining Total Knee Replacements

A Biologic Joint Replacement Strategy for Knee Trauma and Post-Traumatic Osteoarthritis

Zimmer Trabecular Metal Total Ankle PMCF

A Prospective Multicenter Longitudinal Cohort Study of the Mymobility Platform

Liposomal Bupivacaine Versus Standard of Care in Total Knee Surgery

Sleep TO Prevent Post-surgical Pain

Amniotic Umbilical Cord Particulate During Total Knee Arthroplasty

Pain Control With Pre-operative Cryoneurolysis Following TKA

ROSA Robot Used in Total Knee Replacement Post Market Study

Non-inferiority Trial of Oral Tranexamic Acid vs. Intravenous Tranexamic Acid in Joint Replacement Surgery