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ClinicalTrials.gov public records Last synced Nov 4, 2026, 1:37 PM EST

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Showing 1–24 of 251 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Keratosis Clear all

Conditions: Actinic Keratoses
Interventions: Test Product (A): Fluorouracil Cream, 5% topical cream, Reference Product (B): Fluorouracil 5% Topical Cream of Mylan Pharmaceuticals Inc., Morgantown, WV 26505 U.S.A., Placebo Product (C): Test vehicle cream for fluorouracil 5% of Encube Ethicals Pvt. Ltd., India; Drug
Lead sponsor: Encube Ethicals Pvt. Ltd.; Industry
Eligibility: 18 Years and older
Enrollment: 458 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 7
States / cities: Bakersfield, California • Cerritos, California • Lauderdale Lakes, Florida + 3 more

Conditions: Sjogren-Larsson Syndrome (SLS)
Interventions: Not listed
Lead sponsor: University of Nebraska; Other
Eligibility: Not listed
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2023
U.S. locations: 2
States / cities: Omaha, Nebraska • Pittsburgh, Pennsylvania

Conditions: Actinic Keratosis
Interventions: Imiquimod Cream, 3.75%, Zyclara®, Vehicle of Test Product; Drug · Other
Lead sponsor: Teva Pharmaceuticals USA; Industry
Eligibility: 18 Years and older
Enrollment: 589 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 23
States / cities: Tucson, Arizona • Encino, California • Los Angeles, California + 20 more

Conditions: Hearing Loss, Sensorineural, Hearing Loss, Conductive, Hearing Loss, Mixed Conductive-Sensorineural, Otosclerosis, Tympanic Membrane Perforation, Otitis Media With Effusion, Cholesteatoma
Interventions: Not listed
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 20 Years to 89 Years
Enrollment: 320 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2020
U.S. locations: 2
States / cities: Portland, Oregon • Mountain Home, Tennessee

Conditions: Actinic Keratosis
Interventions: GDC 695, Diclofenac Sodium Gel, 3%, Vehicle gel; Drug
Lead sponsor: Balmoral Medical company; Industry
Eligibility: 18 Years and older
Enrollment: 665 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 16
States / cities: Fort Smith, Arkansas • San Diego, California • San Ramon, California + 13 more

Conditions: Skin Cancer, Non-melanoma Skin Cancer, Sun Damaged Skin, Actinic Keratosis
Interventions: Levulan® Kerastick®, BLU-U Blue Light Photodynamic Therapy; Drug
Lead sponsor: Medical Dermatology Specialists; Other
Eligibility: 18 Years and older
Enrollment: 8 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2024
U.S. locations: 1
States / cities: Phoenix, Arizona

Conditions: Burns
Interventions: Fish skin, Cadaver skin; Device
Lead sponsor: Kerecis Ltd.; Industry
Eligibility: 22 Years to 75 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Precancerous Condition
Interventions: liposomal T4N5 lotion; Drug
Lead sponsor: Applied Genetics; Industry
Eligibility: 2 Years to 60 Years
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 1996
U.S. locations: 7
States / cities: Miami Beach, Florida • Ann Arbor, Michigan • Minneapolis, Minnesota + 4 more

Conditions: Keratosis, Actinic
Interventions: Swift System; Device
Lead sponsor: Blackwell Device Consulting; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Actinic Keratosis
Interventions: SOR007 (Uncoated Nanoparticulate Paclitaxel) Ointment, SOR007 Ointment Vehicle; Drug · Other
Lead sponsor: DFB Soria, LLC; Industry
Eligibility: 45 Years to 85 Years
Enrollment: 33 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Irritable Bowel Syndrome
Interventions: Mindfulness training, Psycho-educational support group for women with IBS; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older · Female only
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Actinic Keratoses, Skin Neoplasms
Interventions: Aminolevulinic Acid, Vehicle; Drug · Other
Lead sponsor: DUSA Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 7
States / cities: Irvine, California • San Francisco, California • Miami, Florida + 4 more

Conditions: Actinic Keratosis
Interventions: ALA, Vehicle, IBL 20 mW, IBL 10 mW; Drug · Device
Lead sponsor: DUSA Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 7
States / cities: San Diego, California • Arlington Heights, Illinois • Carmel, Indiana + 4 more

Conditions: Keratosis
Interventions: Imiquimod 5% cream; Drug
Lead sponsor: Graceway Pharmaceuticals, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 84 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2005
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Sjögren-Larsson Syndrome
Interventions: Active topical NS2 1% dermatologic cream, Vehicle placebo 0.0% NS2 dermatologic cream; Drug
Lead sponsor: Aldeyra Therapeutics, Inc.; Industry
Eligibility: 6 Years and older
Enrollment: 12 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 3
States / cities: Omaha, Nebraska • Hershey, Pennsylvania • Fairfax, Virginia

Conditions: Seborrheic Keratosis
Interventions: cryosurgery, Curettage; Procedure
Lead sponsor: Milton S. Hershey Medical Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Hershey, Pennsylvania

Conditions: Actinic Keratosis
Interventions: Imiquimod, Zyclara®, Vehicle Cream; Drug
Lead sponsor: Actavis Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 467 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 27
States / cities: Birmingham, Alabama • Fremont, California • Los Angeles, California + 23 more

Conditions: Actinic Keratosis (AK)
Interventions: Low dose DFD07 once daily, High dose DFD07 once daily, High dose DFD07 twice daily, Placebo twice daily; Drug
Lead sponsor: Dr. Reddy's Laboratories Limited; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 20
States / cities: Cerritos, California • Fremont, California • Palm Springs, California + 14 more

Conditions: Imipramine, Photodynamic Therapy, Actinic Keratosis
Interventions: Imipramine, Vehicle; Drug · Other
Lead sponsor: Wright State University; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Fairborn, Ohio

Conditions: Actinic Keratoses
Interventions: PEP005 (ingenol mebutate) Gel, Vehicle gel; Drug
Lead sponsor: Peplin; Industry
Eligibility: 18 Years and older
Enrollment: 255 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 18
States / cities: Mesa, Arizona • Denver, Colorado • Kissimmee, Florida + 14 more

Conditions: Actinic Keratosis
Interventions: Carac Cream, Placebo Cetaphil cream; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 90 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Actinic Keratoses
Interventions: Cryotherapy, 5Fluorouracil; Procedure · Drug
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years and older
Enrollment: 73 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Actinic Keratosis
Interventions: KX2-391 Ointment; Drug
Lead sponsor: Athenex, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 29 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2016
U.S. locations: 1
States / cities: Austin, Texas

Conditions: Actinic Keratosis
Interventions: LEO 43204 gel 0.018%, LEO 43204 gel 0.1%, LEO 43204 gel 0.037%; Drug
Lead sponsor: LEO Pharma; Industry
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015
U.S. locations: 1
States / cities: Pflugerville, Texas

Search by objective public record fields.

Therapeutic Equivalence of Fluorouracil Cream, 5% Compared With Fluorouracil 5% Topical Cream of MylanPharmaceuticals Inc., U.S.A in the Treatment of Actinic Keratosis

Sjogren-Larsson Syndrome: Natural History, Clinical Variation and Evaluation of Biochemical Markers

Study Comparing Imiquimod Cream, 3.75% to Zyclara® (Imiquimod) Cream, 3.75% in the Treatment of Actinic Keratosis

Wide Frequency Band Test of Hearing in Veterans

Study Comparing GDC 695 and Diclofenac Sodium Gel, 3% in Subjects With Actinic Keratoses

DUSA: Cyclic PDT for the Prevention of AK & NMSC in Solid Organ Transplant Recipients

Fish Skin Compared to Cadaver Skin as Temporary Cover for Full Thickness Burns

T4N5 Liposome Lotion Compared With Placebo Lotion for Preventing Actinic Keratoses in Patients With Xeroderma Pigmentosum

Microwave Treatment for Actinic Keratosis

Study of SOR007 Ointment for Actinic Keratosis

Mindfulness vs. Support Groups for Irritable Bowel Syndrome

ALA-PDT Versus Vehicle PDT for Treatment of AK and Reduction of New NMSC in Solid Organ Transplant Recipients

Phase 3 Study of Levulan With New Blue Light for AK on the Face or Scalp

1-Year Follow up to the 1473-IMIQ Study

A Study of Topical NS2 Cream to Treat Ichthyosis in Sjögren-Larsson Syndrome (SLS)

Is Cryosurgery or Curettage More Effective at Treating Seborrheic Keratoses?

A Study to Evaluate the Safety and Efficacy Imiquimod Cream, 2.5% in Participants With Actinic Keratoses

A Study to Evaluate Two Concentrations of DFD-07 Cream, in Subjects With Actinic Keratosis (AK) of the Face and/or Scalp Over a 12-week Treatment Period

The Effect of Topical Imipramine on Pain and Effectiveness of Topical Photodynamic Therapy

A Multicenter Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel When Used to Treat Actinic Keratoses (AKs) on the Non Head Locations

Cryosurgery and Cream Combination for Actinic Keratosis

Efficacy and Safety of Cryotherapy Versus 5-Fluorouracil in the Treatment of Actinic Keratosis

Ph 1, Single-Center, Safety, Tolerability & Pharmacokinetic Study of KX2 391 Ointment in Subj. w Actinic Keratosis

Pharmacokinetics of LEO 43204 Gel in Actinic Keratosis Administered Under Maximal Use Conditions