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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Ketogenic Diet Clear all
Terminated Not applicable Interventional

Examining the Effects of Diet on Health in Prediabetes With an Online Program

NCT02188823
View directory record Official record
Conditions
Prediabetes
Interventions
Low carbohydrate diet
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 100 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 15, 2017 · Synced Jun 11, 2026, 2:23 AM EDT
Completed No phase listed Observational

Ketogenic Diet in Lafora Disease

NCT00007124
View directory record Official record
Conditions
Lafora Disease
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jun 11, 2026, 2:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

KNA Proof-of-Concept

NCT04968041
View directory record Official record
Conditions
Adherence, Treatment, Retention, Cognitive Impairment, Mild
Interventions
Motivational Interviewing-Cognitive Behavioral Therapy Ketogenic Nutrition Adherence Program
Behavioral
Lead sponsor
Florida State University
Other
Eligibility
60 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Feb 29, 2024 · Synced Jun 11, 2026, 2:23 AM EDT
Terminated Phase 4 Interventional Results available

Synergistic Enteral Regimen for Treatment of the Gangliosidoses

NCT02030015
View directory record Official record
Conditions
GM1 Gangliosidoses, GM2 Gangliosidoses, Tay-Sachs Disease, Sandhoff Disease
Interventions
miglustat, Ketogenic Diet
Drug · Other
Lead sponsor
University of Minnesota
Other
Eligibility
Up to 204 Months
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 13, 2021 · Synced Jun 11, 2026, 2:23 AM EDT
Completed Phase 2 Interventional

7-Keto DHEA for the Treatment of PTSD

NCT01861847
View directory record Official record
Conditions
PTSD
Interventions
7-Keto Dehydroepiandrosterone, Placebo
Drug
Lead sponsor
Humanetics Corporation
Industry
Eligibility
18 Years to 64 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Bay Pines, Florida
Source: ClinicalTrials.gov public record
Updated Oct 28, 2015 · Synced Jun 11, 2026, 2:23 AM EDT
Active, not recruiting Not applicable Interventional

Ketogenic Diet in People With Schizophrenia

NCT05968638
View directory record Official record
Conditions
Schizophrenia, Schizo Affective Disorder
Interventions
Regular Diet, Ketogenic Diet
Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 64 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Catonsville, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 11, 2025 · Synced Jun 11, 2026, 2:23 AM EDT
Completed Phase 1 Interventional

Leucine Enriched Essential Amino Acid Powder as an Add-on to a Classic Ketogenic Diet in Refractory Epilepsy

NCT06387186
View directory record Official record
Conditions
Refractory Epilepsy, Drug Resistant Epilepsy
Interventions
Leucine-Enriched Essential Amino Acid powder
Drug
Lead sponsor
Elizabeth Anne Thiele
Other
Eligibility
2 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jun 11, 2026, 2:23 AM EDT
Completed Phase 1 Interventional

Ketogenic Diet as Adjunctive Treatment in Refractory/End-stage Glioblastoma Multiforme: a Pilot Study

NCT01865162
View directory record Official record
Conditions
Glioblastoma Multiforme
Interventions
ketogenic diet
Other
Lead sponsor
Mid-Atlantic Epilepsy and Sleep Center, LLC
Other
Eligibility
18 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2021
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 8, 2022 · Synced Jun 11, 2026, 2:23 AM EDT
Completed Phase 1 Interventional Results available

Acute Effects of Medium Chain Triglyceride (MCT) Nutritional Ketosis on Parkinson's Disease (PD) Symptoms and Biomarkers (MCT-PD)

NCT04584346
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Liquigen MCT oil, Standard American Diet
Dietary Supplement · Other
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
50 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 12, 2022 · Synced Jun 11, 2026, 2:23 AM EDT
Suspended Not applicable Interventional

Keto-Brain:Investigating the Use of Ketogenic Diets in Brain Metastases

NCT05428852
View directory record Official record
Conditions
Brain Metastases, Adult
Interventions
Laboratory Biomarker Analysis, Neurocognitive Assessment, Questionnaire Administration, Fitbit, Dietary Intervention
Other · Device · Dietary Supplement
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Jun 11, 2026, 2:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ketogenic Diet for Obesity Hypoventilation Syndrome

NCT04108819
View directory record Official record
Conditions
Obesity Hypoventilation Syndrome, Ketogenic Dieting, Hypercapnic Respiratory Failure
Interventions
Ketogenic Diet
Dietary Supplement
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 30, 2022 · Synced Jun 11, 2026, 2:23 AM EDT
Recruiting Phase 1 Interventional

Ketogenic Diet for Prevention of Epileptic Spasms in Infantile Onset Genetic Epilepsies

NCT06700811
View directory record Official record
Conditions
Developmental and Epileptic Encephalopathies, Epileptic Spasms, Genetic Epilepsy, Neonatal and Infant Epilepsy
Interventions
Ketogenic diet
Drug
Lead sponsor
Heather Olson
Other
Eligibility
0 Days to 9 Months
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 1, 2026 · Synced Jun 11, 2026, 2:23 AM EDT
Completed Not applicable Interventional

Brain Small Chain Fatty Acid Metabolism in Bipolar Disorder: Ketones

NCT06335875
View directory record Official record
Conditions
Bipolar Disorder
Interventions
Ketone Ester Beverage, Low Glycemic Index Diet
Dietary Supplement · Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 11, 2025 · Synced Jun 11, 2026, 2:23 AM EDT
Completed Phase 2 Interventional Results available

Compatibility of C7 With Ketogenic Diet in Patients Diagnosed With G1D

NCT03301532
View directory record Official record
Conditions
GLUT1DS1
Interventions
Triheptanoin
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
30 Months to 35 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 16, 2024 · Synced Jun 11, 2026, 2:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of a Modified Ketogenic-Mediterranean Diet on Alzheimer's Disease

NCT02984540
View directory record Official record
Conditions
Mild Cognitive Impairment, Insulin Resistance
Interventions
Low-Carbohydrate Diet, Low-Fat Diet
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
50 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 27, 2025 · Synced Jun 11, 2026, 2:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Contrasting Ketogenic and Mediterranean Diets in Individuals With Type 2 Diabetes and Prediabetes: The Keto-Med Trial

NCT03810378
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, PreDiabetes
Interventions
Mediterranean Diet (Med-Plus), Well-Formulated Ketogenic Diet (WFKD)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 20, 2023 · Synced Jun 11, 2026, 2:23 AM EDT
Completed Phase 1 Interventional

Ketogenic Diet in Combination With Standard-of-care Radiation and Temozolomide for Patients With Glioblastoma

NCT03451799
View directory record Official record
Conditions
GBM, Glioblastoma
Interventions
Ketogenic Diet, Standard-of-care radiation, Standard-of-care Temozolomide
Other · Radiation · Drug
Lead sponsor
Jethro Hu
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Jun 11, 2026, 2:23 AM EDT
Enrolling by invitation Phase 1Phase 2 Interventional

Improving Cardiovascular Health Risks in Adults With Epilepsy on a Modified Atkins Diet

NCT06369571
View directory record Official record
Conditions
Epilepsy, Dyslipidemia
Interventions
Atorvastatin 10mg, Modification of dietary fat composition
Drug · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Jun 11, 2026, 2:23 AM EDT
Completed Phase 4 Interventional

Lifestyle Modification for Obesity-Related Type 2 Diabetes

NCT00415688
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Overweight, Obesity
Interventions
Low carbohydrate, ketogenic diet, Low glycemic index, reduced calorie diet
Behavioral
Lead sponsor
Robert C. Atkins Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 24, 2006 · Synced Jun 11, 2026, 2:23 AM EDT
Terminated Not applicable Interventional

Ketogenic Diet Phase 1 for Head & Neck Cancer

NCT01975766
View directory record Official record
Conditions
Head and Neck Neoplasms
Interventions
Ketogenic diet, External beam radiation therapy
Dietary Supplement · Device
Lead sponsor
Bryan Allen
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 25, 2018 · Synced Jun 11, 2026, 2:23 AM EDT
Completed Not applicable Interventional

Modified Atkins Diet Plus KetoCal for Adult Epilepsy

NCT01834482
View directory record Official record
Conditions
Epilepsy, Seizure, Medically Resistant Epilepsy, Medically Resistant Seizures
Interventions
Modified Atkins diet, KetoCal
Dietary Supplement
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 30, 2018 · Synced Jun 11, 2026, 2:23 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Effects of a Ketogenic Diet on Body Weight and Cardiovascular Risk Factors

NCT00498394
View directory record Official record
Conditions
Obesity
Interventions
Clinical diet trial
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older · Female only
Enrollment
103 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2002
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 9, 2007 · Synced Jun 11, 2026, 2:23 AM EDT
Recruiting Phase 3 Interventional

Ketogenic Diet for New-Onset Absence Epilepsy

NCT04274179
View directory record Official record
Conditions
Absence Epilepsy, Ketogenic Dieting, Epilepsy, Absence
Interventions
Modified Atkins Diet, Absence epilepsy medications
Other · Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
3 Years to 12 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Jun 11, 2026, 2:23 AM EDT
Completed Not applicable Interventional

Use of the Atkins Diet for Adults With Intractable Epilepsy

NCT00121927
View directory record Official record
Conditions
Epilepsy
Interventions
Atkins diet (15 grams/day carbohydrates)
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 26, 2010 · Synced Jun 11, 2026, 2:23 AM EDT