Independent directory Public ClinicalTrials.gov records United States
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ClinicalTrials.gov public records Last synced Oct 7, 2026, 3:35 PM EDT

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Showing 25–48 of 1,210 matching trials from the live ClinicalTrials.gov search.
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip
Interventions
Celecoxib
Drug
Lead sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
875 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
67
States / cities
Huntsville, Alabama • Peoria, Arizona • Phoenix, Arizona + 58 more
Conditions
Obesity, Knee Osteoarthritis
Interventions
InBody Band 2
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Osteo Arthritis Knee, Pain
Interventions
Intervention -- "Headspace" mindfulness application, Control -- "My Water Balance" application
Device
Lead sponsor
jilliansylvester
Federal
Eligibility
18 Years to 74 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Scott Air Force Base, Illinois
Conditions
Osteoarthritis, Knee
Interventions
Ibuprofen, celecoxib, placebo
Drug · Other
Lead sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Industry
Eligibility
40 Years and older
Enrollment
393 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
33
States / cities
Anniston, Alabama • Phoenix, Arizona • Anaheim, California + 30 more
Conditions
Osteoarthritis, Pain
Interventions
Placebo Gel, OLT1177 Gel
Drug
Lead sponsor
Olatec Therapeutics, Inc.
Industry
Eligibility
45 Years to 80 Years
Enrollment
202 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
13
States / cities
Birmingham, Alabama • Milford, Connecticut • DeLand, Florida + 10 more
Conditions
Osteoarthritis, Knee, Osteoarthritis of the Knee
Interventions
Placebo, Cannabidiol (CBD), Tetrahydrocannabinol (Marinol® or generic equivalent (e.g., dronabinol)
Drug
Lead sponsor
Steven E Harte, PhD
Other
Eligibility
21 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Osteoarthritis, Knee
Interventions
Off-the-Shelf Implant Total Knee Replacement, Customized Implant Total Knee Replacement
Device
Lead sponsor
Restor3D
Industry
Eligibility
18 Years and older
Enrollment
59 participants
Timeline
2020 – 2022
U.S. locations
1
States / cities
Kettering, Ohio
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Intravenous (IV) Hydrocortisone for TKA (Total Knee Arthroplasty)

NCT04082533
Conditions
Pain, Arthrofibrosis, Osteoarthritis, Knee
Interventions
Hydrocortisone, Dextrose 5% in water (D5W)
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 83 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
New York, New York
Conditions
Osteoarthritis
Interventions
Flavocoxid, Placebo
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
40 Years to 75 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Birmingham, Alabama
Completed Not applicable Interventional Accepts healthy volunteers

Acceptance and Commitment Therapy Delivered by Automated Software Messaging

NCT04329897
Conditions
Hip Osteoarthritis, Knee Osteoarthritis, Mental Stress, Coronavirus
Interventions
Software Messaging
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Arthritis, Knee Osteoarthritis, Arthropathy of Knee
Interventions
Stated-Preferences Evaluation Instrument
Other
Lead sponsor
Duke University
Other
Eligibility
40 Years to 80 Years
Enrollment
348 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

TENS Effectiveness and Knee Osteoarthritis in Humans

NCT01354054
Conditions
Knee Osteoarthritis
Interventions
High Frequency TENS, Low frequency TENS, Placebo TENS
Procedure
Lead sponsor
University of Iowa
Other
Eligibility
30 Years to 95 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Osteoarthritis of Knee
Interventions
Triamcinolone Acetonide Low Dose, Triamcinolone Acetonide Standard Dose
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
55 Years to 85 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Jacksonville, Florida
Conditions
Osteoarthritis
Interventions
Mesenchymal Stem Cell Injection
Biological
Lead sponsor
TricelX Inc.
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Frisco, Texas
Conditions
Osteoarthritis, Knee, Obesity
Interventions
HFFS
Device
Lead sponsor
University of Southern Mississippi
Other
Eligibility
30 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Hattiesburg, Mississippi
Conditions
Osteoarthritis of the Knee
Interventions
Stryker Triathlon Tritanium primary knee
Device
Lead sponsor
Scott Sporer
Other
Eligibility
18 Years to 80 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2015
U.S. locations
1
States / cities
Winfield, Illinois
Conditions
Knee Osteoarthritis
Interventions
Wearable sensor-based exercise training
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 90 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Tucson, Arizona
Conditions
Osteo Arthritis Knee
Interventions
Behavioral Health, Health Education
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
65 Years and older
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Pain, Chronic Back Pain, Chronic Low Back Pain, Osteoarthritis Pain In The Hip or Knee
Interventions
Nucynta ER
Drug
Lead sponsor
Janssen Scientific Affairs, LLC
Industry
Eligibility
18 Years to 74 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
7
States / cities
Jacksonville, Florida • Prairie Village, Kansas • Mandeville, Louisiana + 4 more
Conditions
Osteoarthritis, Knee
Interventions
active tDCS paired with active MBM, sham tDCS paired with sham MBM
Device
Lead sponsor
Florida State University
Other
Eligibility
50 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Tallahassee, Florida
Conditions
Whole Body Vibration, Osteo Arthritis Knee
Interventions
Sub Acute Whole Body Vibration Training
Device
Lead sponsor
Augusta University
Other
Eligibility
40 Years to 75 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Augusta, Georgia
Conditions
Osteoarthritis, Knee
Interventions
PF-04136309, Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 75 Years
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
18
States / cities
DeLand, Florida • South Miami, Florida • Overland Park, Kansas + 10 more
Conditions
Knee Osteoarthritis
Interventions
SM04690, Placebo, Sham
Drug · Other
Lead sponsor
Biosplice Therapeutics, Inc.
Industry
Eligibility
40 Years to 80 Years
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
74
States / cities
Anniston, Alabama • Birmingham, Alabama • Mobile, Alabama + 68 more
Conditions
Knee Osteoarthritis, Knee Pain Chronic, Knee Arthritis, Knee Arthropathy
Interventions
Dorsal Root Ganglion Stimulation
Device
Lead sponsor
Kenneth B Chapman
Other
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
New York, New York