- Conditions
- Osteoarthritis
- Interventions
- Adipose Derived (AD) Stromal Vascular Fraction (SVF)
- Genetic
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 18 Years to 45 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
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Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
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Showing 1–24
of 124
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Knee Injuries, Shoulder Injuries, Rotator Cuff Disease, Meniscus Tear, Patellofemoral Pain
- Interventions
- eRehab, Formal Physical Therapy
- Other
- Lead sponsor
- Charlotte Sports Medicine Institute, PA
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2013
- U.S. locations
- 2
- States / cities
- Prince Frederick, Maryland • Charlotte, North Carolina
- Conditions
- Rupture of Anterior Cruciate Ligament, Osteoarthritis
- Interventions
- Not listed
- Lead sponsor
- Vanderbilt University
- Other
- Eligibility
- 14 Years to 55 Years
- Enrollment
- 432 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2025
- U.S. locations
- 4
- States / cities
- St Louis, Missouri • Cleveland, Ohio • Columbus, Ohio + 1 more
- Conditions
- Articular Cartilage Disorder of Knee, Cartilage Damage, Microfractures
- Interventions
- microfracture surgery + HST003
- Biological
- Lead sponsor
- Histogen
- Industry
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2023
- U.S. locations
- 5
- States / cities
- Vail, Colorado • Bradenton, Florida • Bethesda, Maryland + 2 more
- Conditions
- Orthopedic Disorders, Injury of Anterior Cruciate Ligament
- Interventions
- High Pressure Injection, Low Pressure Injection
- Procedure
- Lead sponsor
- University of Miami
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 26 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2015 – 2016
- U.S. locations
- 1
- States / cities
- Miami, Florida
- Conditions
- Osteoarthritis, Knee, Post-traumatic Osteoarthritis, ACL Tear
- Interventions
- Metformin, Placebo
- Drug
- Lead sponsor
- Brigham and Women's Hospital
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 512 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2029
- U.S. locations
- 9
- States / cities
- Atlanta, Georgia • Iowa City, Iowa • Lexington, Kentucky + 6 more
- Conditions
- Articular Cartilage Disorder of Knee, Articular Cartilage; Degeneration
- Interventions
- Autologous peripheral blood stem cells and hyaluronic acid, Hyaluronic acid
- Biological · Other
- Lead sponsor
- KLSMC Stem Cells, Inc.
- Industry
- Eligibility
- 18 Years to 55 Years
- Enrollment
- 120 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2022
- U.S. locations
- 1
- States / cities
- Gulf Breeze, Florida
- Conditions
- Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury), Phantom Limb Pain
- Interventions
- Distractor and Lower limb VR
- Device
- Lead sponsor
- University of Pennsylvania
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 14 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Patellofemoral Joint Dislocation, Bicep Tendon Rupture
- Interventions
- Blood Flow Restriction (BFR) Therapy, Physical Therapy
- Other
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years to 80 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Ligament Injury, Ligament; Laxity, Tendon Rupture, Tendon Injuries
- Interventions
- methylsulfonylmethane, Placebo
- Dietary Supplement · Other
- Lead sponsor
- University of California, Davis
- Other
- Eligibility
- 18 Years to 30 Years · Female only
- Enrollment
- 32 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019
- U.S. locations
- 1
- States / cities
- Davis, California
- Conditions
- Chronic Patellar Tendinopathy, Chronic PT
- Interventions
- platelet rich plasma, saline
- Biological · Other
- Lead sponsor
- University of Wisconsin, Madison
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 29 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2014 – 2024
- U.S. locations
- 2
- States / cities
- Madison, Wisconsin
- Conditions
- Surgical Site Infection, Zonulin
- Interventions
- Zonulin Biomarker
- Diagnostic Test
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2021
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- Patellar Tendinopathy, Patellar Tendinitis, Patellar Tendon Pain, Patellar Tendinosis, Jumper's Knee
- Interventions
- Exercise Treatment, Pain- Guided Activity Modification
- Other
- Lead sponsor
- University of Delaware
- Other
- Eligibility
- 16 Years to 40 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Newark, Delaware
- Conditions
- Arthroplasty, Replacement, Knee, Knee Injuries
- Interventions
- ALGRX 4975
- Drug
- Lead sponsor
- AlgoRx Pharmaceuticals
- Industry
- Eligibility
- 35 Years to 80 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005
- U.S. locations
- 1
- States / cities
- Birmingham, Alabama
- Conditions
- Knee Injuries, Knee Osteoarthritis, Patellofemoral Syndrome
- Interventions
- Limber Digital Application, Physical therapy Therapy
- Device · Behavioral
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Patella Dislocation
- Interventions
- medial patellofemoral reconstruction, Non-operative group
- Procedure
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 12 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2026 – 2032
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Degenerative Joint Disease, Osteoarthritis, Knee Injury, Trauma, Connective Tissue Disorder, Pain, Loss of Function
- Interventions
- Not listed
- Lead sponsor
- Loma Linda University
- Other
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2016
- U.S. locations
- 1
- States / cities
- San Bernardino, California
- Conditions
- Spine Degeneration, Hip Arthritis, Knee Osteoarthritis, Hip Fractures
- Interventions
- App for in-bed conditioning exercises, Usual care
- Device · Other
- Lead sponsor
- Yale University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- New Haven, Connecticut
- Conditions
- Knee Injuries, Knee Osteoarthritis
- Interventions
- Cutaneous Stimulation, Knee Sleeve
- Device
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 38 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Stanford, California
- Conditions
- Aseptic Loosening, Infection, Bone Loss, MCL - Medial Collateral Ligament Rupture of the Knee, Periprosthetic Fractures
- Interventions
- Freedom Knee PCK Components
- Device
- Lead sponsor
- Maxx Orthopedics Inc
- Industry
- Eligibility
- 40 Years to 80 Years
- Enrollment
- 300 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2022
- U.S. locations
- 1
- States / cities
- Bradenton, Florida
- Conditions
- Knee Injuries, Knee Injuries and Disorders, Opioid Use
- Interventions
- Opioid Reduction Program
- Behavioral
- Lead sponsor
- University of Tennessee
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 85 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2022
- U.S. locations
- 1
- States / cities
- Memphis, Tennessee
- Conditions
- Knee Injuries, Knee Osteoarthritis, Knee Arthritis
- Interventions
- B-FREE
- Other
- Lead sponsor
- Michigan Technological University
- Other
- Eligibility
- 40 Years to 75 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2025
- U.S. locations
- 1
- States / cities
- Houghton, Michigan
- Conditions
- Knee Injuries
- Interventions
- Blood Flow Restriction, Standard rehabilitation
- Other
- Lead sponsor
- Keller Army Community Hospital
- Federal
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 2
- States / cities
- West Point, New York • Fort Bragg, North Carolina
- Conditions
- Patellar Dislocation, Recurrent, Patellar Dislocation, Patellar Instability, Patellofemoral Dislocation, Patellofemoral Joint Dislocation, Patellofemoral Disorder
- Interventions
- Medial Patellofemoral Ligament (MPFL) Reconstruction
- Procedure
- Lead sponsor
- Hospital for Special Surgery, New York
- Other
- Eligibility
- 10 Years to 35 Years
- Enrollment
- 850 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2027
- U.S. locations
- 16
- States / cities
- Redwood City, California • Gainesville, Florida • Chicago, Illinois + 10 more