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ClinicalTrials.gov public records Last synced Oct 23, 2026, 3:14 AM EDT

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Showing 1–24 of 47 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Knee Range of Motion Clear all
Not listed Not applicable Interventional

Measuring Every Day (MED) Study

NCT03010605
View directory record Official record
Conditions
Total Knee Arthroplasty
Interventions
Measuring Every Day Device, Physical Therapy
Device · Other
Lead sponsor
The Christ Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 18, 2018 · Synced Oct 23, 2026, 3:14 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Mymobility Knee ROM

NCT06863428
View directory record Official record
Conditions
Knee Range of Motion
Interventions
Not listed
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Auburn Hills, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 23, 2026, 3:14 AM EDT
Terminated No phase listed Observational

Evaluation of the VEGA Knee System® Range of Motion

NCT01768871
View directory record Official record
Conditions
Patients With Total Knee Arthroplasty Using the VEGA System
Interventions
Not listed
Lead sponsor
Aesculap Implant Systems
Industry
Eligibility
21 Years to 75 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
3
States / cities
Denver, Colorado • Vero Beach, Florida • Asheville, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 14, 2018 · Synced Oct 23, 2026, 3:14 AM EDT
Completed Not applicable Interventional Results available

An Investigation of Functional Improvements in the RHEO KNEE Compared to Hydraulic Microprocessor Controlled Knees (MPKs)

NCT04023578
View directory record Official record
Conditions
Prosthesis User, Amputation
Interventions
RHEO KNEE XC
Device
Lead sponsor
Össur Iceland ehf
Industry
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
4
States / cities
Orlando, Florida • Flowood, Mississippi • Fort Worth, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 6, 2020 · Synced Oct 23, 2026, 3:14 AM EDT
Completed No phase listed Observational

Osteoarthritis: Weakness From Inflammation

NCT00104312
View directory record Official record
Conditions
Osteoarthritis
Interventions
Not listed
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
50 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 29, 2009 · Synced Oct 23, 2026, 3:14 AM EDT
Completed Not applicable Interventional

Photographic Evidence on Total Knee Arthroplasty Outcomes

NCT07223359
View directory record Official record
Conditions
Osteoarthritis (OA) of the Knee
Interventions
Photographic Evidence of Postoperative Knee Range of Motion, Standard Postoperative Care
Behavioral
Lead sponsor
Loyola University
Other
Eligibility
18 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Maywood, Illinois • Melrose Park, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 31, 2025 · Synced Oct 23, 2026, 3:14 AM EDT
Suspended Not applicable Interventional

Low Frequency Ultrasound for Osteoarthritis Healing and Rehabilitation

NCT06562374
View directory record Official record
Conditions
Osteo Arthritis Knee, Age Related Osteoporosis, Pain, Knee Joint Contracture
Interventions
Low Frequency Ultrasound Therapy
Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
40 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 6, 2026 · Synced Oct 23, 2026, 3:14 AM EDT
Terminated Not applicable Interventional

PB125, Osteoarthritis, Pain, Mobility, and Energetics

NCT04638387
View directory record Official record
Conditions
Osteoarthritis, Knee, Muscle Weakness, Pain, Joint
Interventions
PB125, Placebo
Dietary Supplement
Lead sponsor
Colorado State University
Other
Eligibility
50 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 14, 2022 · Synced Oct 23, 2026, 3:14 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Tourniquet Pressure in Primary Total Knee Arthroplasty

NCT02830087
View directory record Official record
Conditions
Tourniquets, Knee Arthroplasty, Total, Knee Replacement, Total
Interventions
Tourniquet Cuff Pressure
Procedure
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
2
States / cities
Bermuda Run, North Carolina • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 19, 2018 · Synced Oct 23, 2026, 3:14 AM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Intravenous (IV) Hydrocortisone for TKA (Total Knee Arthroplasty)

NCT04082533
View directory record Official record
Conditions
Pain, Arthrofibrosis, Osteoarthritis, Knee
Interventions
Hydrocortisone, Dextrose 5% in water (D5W)
Drug
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 83 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 23, 2026, 3:14 AM EDT
Completed Not applicable Interventional

ROM Outcomes in Patients Undergoing a Primary TKA

NCT04217486
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Patient will be shown a photograph of their knee at 2 weeks postop, Patient will not be shown a photograph of their knee at 2 weeks postop
Other
Lead sponsor
University of Louisville
Other
Eligibility
22 Years to 89 Years
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Sep 16, 2021 · Synced Oct 23, 2026, 3:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Reparel Knee Sleeve vs. TED Hose for Post-op Swelling, Pain and Range of Motion After Total Knee Replacement

NCT04751942
View directory record Official record
Conditions
Osteoarthritis Knees Both
Interventions
Non-compressive Bioactive Garment, thrombo-embolic deterrent
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Beachwood, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 4, 2025 · Synced Oct 23, 2026, 3:14 AM EDT
Completed Early Phase 1 Interventional

Anterior Heel Wedge to Treat Flexion Contracture After Total Knee Arthroplasty

NCT07620145
View directory record Official record
Conditions
Knee Flexion Contracture, Total Knee Arthroplasty (TKA)
Interventions
Anterior heel wedge
Device
Lead sponsor
University of North Carolina, Charlotte
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 23, 2026, 3:14 AM EDT
Completed Phase 4 Interventional Results available

A Real-World Evidence Study to Evaluate the Effects of Voltaren Use on Mobility and Quality of Life in Participants With Knee Osteoarthritis Pain

NCT06379893
View directory record Official record
Conditions
Pain
Interventions
Voltaren Gel
Drug
Lead sponsor
HALEON
Industry
Eligibility
40 Years to 85 Years
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
2
States / cities
Marrero, Louisiana • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 23, 2026, 3:14 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Effects of Oral Tranexamic Acid Following Total Knee Arthroplasty

NCT06479161
View directory record Official record
Conditions
Postoperative Pain
Interventions
Tranexamic acid
Drug
Lead sponsor
Matthew Grosso, MD
Other
Eligibility
18 Years to 89 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Dec 13, 2024 · Synced Oct 23, 2026, 3:14 AM EDT
Not yet recruiting Not applicable Interventional

Developing a Nonpharmacological Pain Intervention for Community-dwelling Older Adults With Dementia

NCT06264362
View directory record Official record
Conditions
Pain, Chronic, Dementia, Mild, Mobility Limitation, Physical Disability, Osteo Arthritis Knee, Mild Cognitive Impairment
Interventions
Tailored Physical Activity Program
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
60 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 11, 2025 · Synced Oct 23, 2026, 3:14 AM EDT
Completed Not applicable Interventional

Aquatic Power Training

NCT00904319
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Aquatic Power Training
Other
Lead sponsor
University of Iowa
Other
Eligibility
50 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jun 25, 2010 · Synced Oct 23, 2026, 3:14 AM EDT
Completed Not applicable Interventional

Dry Needling and Stretching vs. Stretching Alone on Hamstring Flexibility in Patients With Knee Pain

NCT02498704
View directory record Official record
Conditions
Mobility Limitation
Interventions
Dry Needling, Sham Needling
Procedure · Other
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
18 Years to 40 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
West Point, New York
Source: ClinicalTrials.gov public record
Updated Feb 23, 2016 · Synced Oct 23, 2026, 3:14 AM EDT
Completed Not applicable Interventional

Improving Walking in Older Adults With Knee Osteoarthritis

NCT00583245
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Gait Training
Other
Lead sponsor
University of Iowa
Other
Eligibility
60 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 10, 2017 · Synced Oct 23, 2026, 3:14 AM EDT
Suspended Phase 4 Interventional Accepts healthy volunteers

Effect of Colchicine on Range of Motion After Manipulation Under Anesthesia for the Stiff Total Knee Replacement

NCT02926248
View directory record Official record
Conditions
Manipulation Under Anesthesia
Interventions
Colchicine, Placebo
Drug · Other
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years and older
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Oct 23, 2026, 3:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Platform Exercise Training

NCT01239823
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
Whole Body Vibration Training, Exercise without vibration
Other
Lead sponsor
University of Iowa
Other
Eligibility
45 Years to 60 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 11, 2011 · Synced Oct 23, 2026, 3:14 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Study of Wearable Interventions for Improving Mobility of Individuals With Knee Osteoarthritis

NCT07652437
View directory record Official record
Conditions
Knee Osteoarthristis
Interventions
Dephy Exoboot
Device
Lead sponsor
Massachusetts Institute of Technology
Other
Eligibility
21 Years to 100 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 23, 2026, 3:14 AM EDT
Not yet recruiting Not applicable Interventional

Effect of a Microprocessor-controlled Prosthetic Knee Joint on K2 Level Ambulators

NCT07103798
View directory record Official record
Conditions
Transfemoral Amputation, Limb Loss, Limb Absence
Interventions
College Park ICON, Conventional NMPK
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
45 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
2
States / cities
Chicago, Illinois • Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 7, 2026 · Synced Oct 23, 2026, 3:14 AM EDT
Completed Not applicable Interventional

Overcoming TWEAK Signaling to Restore Muscle and Mobility After Joint Replacement

NCT02628795
View directory record Official record
Conditions
Osteoarthritis
Interventions
PRT + FM, Usual Care
Behavioral · Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
40 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jul 7, 2021 · Synced Oct 23, 2026, 3:14 AM EDT