- Conditions
- Pain
- Interventions
- Suzetrigine, Placebo
- Drug
- Lead sponsor
- Vertex Pharmaceuticals Incorporated
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 2
- States / cities
- Bellaire, Texas • Houston, Texas
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.
These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 1–24
of 803
matching trials from the live ClinicalTrials.gov search.
- Conditions
- Postsurgical Pain
- Interventions
- CA-008, Placebo
- Drug
- Lead sponsor
- Concentric Analgesics
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 55 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Houston, Texas
- Conditions
- Knee Osteoarthritis, Knee Osteoarthritis (Knee OA), Knee Osteoarthritis (OA)
- Interventions
- Registry (N/A)
- Other
- Lead sponsor
- University of Chicago
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2028
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Osteoarthritis, Total Knee Arthroplasty
- Interventions
- Game Ready Injury Treatment System (CoolSystems Inc.), Ice with compressive bandages
- Device · Other
- Lead sponsor
- CoolSystems, Inc.
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 224 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 10
- States / cities
- San Diego, California • Honolulu, Hawaii • Winfield, Illinois + 7 more
- Conditions
- Knee Arthroplasty, Total
- Interventions
- LEGION Hinge Knee System
- Device
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 47 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2028
- U.S. locations
- 3
- States / cities
- Iowa City, Iowa • New York, New York • Portland, Oregon
- Conditions
- Postoperative Complications, Memory Disorders
- Interventions
- pulsatile saline lavage, carbon dioxide lavage
- Device
- Lead sponsor
- Kinamed Incorporated
- Industry
- Eligibility
- 50 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2011
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Post-Operative Pain
- Interventions
- Sufentanil NanoTab PCA System/15 mcg, morphine IV PCA
- Drug
- Lead sponsor
- Talphera, Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 357 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012
- U.S. locations
- 16
- States / cities
- Florence, Alabama • Montgomery, Alabama • Sheffield, Alabama + 13 more
- Conditions
- Arthritis Knee, Knee Osteoarthritis, Pain, Postoperative
- Interventions
- Methylprednisolone 4 milligram Tab, Dexamethasone injection
- Drug
- Lead sponsor
- F. Johannes Plate
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 2
- States / cities
- Monroeville, Pennsylvania • Pittsburgh, Pennsylvania
- Conditions
- Total Knee Arthroplasty
- Interventions
- Virtual Reality Immersive Relaxation, Immersive Audio Experience, Sham Virtual Reality Experience
- Other
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 86 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Postoperative Urinary Retention, Total Hip Arthroplasty, Total Knee Arthroplasty
- Interventions
- Indwelling foley catheter, No foley catheter
- Device · Other
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 388 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2020 – 2022
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Total Knee Replacement
- Interventions
- Interview
- Other
- Lead sponsor
- Invibio Ltd
- Industry
- Eligibility
- Not listed
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Primary Total Knee Arthroplasty, Intraosseous Morphine Injection, Knee Osteoarthritis
- Interventions
- Morphine, Vancomycin
- Drug
- Lead sponsor
- Carilion Clinic
- Other
- Eligibility
- 18 Years to 100 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Roanoke, Virginia
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- Triathlon® CR Total Knee System
- Device
- Lead sponsor
- Stryker Orthopaedics
- Industry
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 419 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2017
- U.S. locations
- 11
- States / cities
- Phoenix, Arizona • Miami, Florida • Columbus, Georgia + 8 more
- Conditions
- Osteoarthritis
- Interventions
- Total and Unicompartment Knee Replacement
- Device
- Lead sponsor
- Medacta USA
- Industry
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2026
- U.S. locations
- 1
- States / cities
- Leesburg, Florida
- Conditions
- Knee Osteoarthritis, Hip Osteoarthritis, Knee Arthritis, Hip Arthritis
- Interventions
- Total knee or Hip Arthroplasty
- Procedure
- Lead sponsor
- University of Arkansas
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 500 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- Little Rock, Arkansas
- Conditions
- Arthroplasty, Replacement, Knee, Anesthesia, Conduction, Acute Pain
- Interventions
- adductor canal block, SPANK, Ropivacaine
- Procedure · Drug
- Lead sponsor
- Bruce Ben-David
- Other
- Eligibility
- 19 Years to 90 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Knee Osteoarthritis, Pain Management
- Interventions
- bupivacaine liposome injectable suspension, Bupivacaine Hydrochloride
- Drug
- Lead sponsor
- Pacira Pharmaceuticals, Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 167 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022
- U.S. locations
- 6
- States / cities
- Little Rock, Arkansas • Pasadena, California • Dayton, Ohio + 3 more
- Conditions
- Infected Total Hip or Knee Arthroplasty
- Interventions
- Not listed
- Lead sponsor
- Central DuPage Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2012
- U.S. locations
- 2
- States / cities
- Chicago, Illinois • Winfield, Illinois
- Conditions
- Flexion Contracture Following Total Knee Replacement
- Interventions
- Botox, placebo
- Drug
- Lead sponsor
- Rothman Institute Orthopaedics
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 140 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2012
- U.S. locations
- 2
- States / cities
- Bryn Mawr, Pennsylvania • Lankenau, Pennsylvania
- Conditions
- Pain, Postoperative, Total Knee Arthroplasty
- Interventions
- Duloxetine, Placebos
- Drug
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 241 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Osteoarthritis, Post Traumatic Degenerative Disease
- Interventions
- EPIK™ uni-compartmental knee
- Device
- Lead sponsor
- Encore Medical, L.P.
- Industry
- Eligibility
- 18 Years to 60 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2012
- U.S. locations
- 1
- States / cities
- Kyle, Texas
- Conditions
- Knee Arthritis, Hip Arthritis
- Interventions
- Wagner Pain Algometer, Dynamometer
- Device
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 201 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Durham, North Carolina
- Conditions
- Knee Injuries
- Interventions
- Spinal Surgery, Verasense Knee System device
- Procedure · Device
- Lead sponsor
- NYU Langone Health
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 52 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2022
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Osteoarthritis, Knee, Total Knee Arthroplasty, Chronic Postsurgical Pain
- Interventions
- GlyNAC (combination of glycine and n-acetylcysteine), Placebo
- Drug
- Lead sponsor
- Vanderbilt University Medical Center
- Other
- Eligibility
- 50 Years and older
- Enrollment
- 148 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2029
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee