Independent directory Public ClinicalTrials.gov records United States
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Showing 1–24 of 868 matching trials from the live ClinicalTrials.gov search.
Conditions
Post Operative Analgesia
Interventions
Selective Tibial Nerve block, Sciatic Nerve Block
Procedure
Lead sponsor
Trinity Health Of New England
Other
Eligibility
18 Years to 85 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Hartford, Connecticut
Conditions
Knee Arthritis, Knee Osteoarthritis
Interventions
Suzetrigine
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 95 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
3
States / cities
Atlanta, Georgia
Conditions
Osteoarthritis
Interventions
Bupivacaine
Drug
Lead sponsor
Columbia University
Other
Eligibility
Not listed
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Results available

Adductor Canal Catheter Effectiveness and Safety Study

NCT04639128
Conditions
Total Knee Replacement Surgery
Interventions
Adductor Canal Catheter
Device
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
San Leandro, California
Conditions
Osteoarthritis: Joint Replacement Surgery
Interventions
CLARIX FLO, Saline
Other
Lead sponsor
BioTissue Holdings, Inc
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Orange Park, Florida
Conditions
Knee Osteoarthritis, Total Knee Arthroplasty (TKA)
Interventions
Pain Scale/Medication Log
Other
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years and older
Enrollment
375 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Skokie, Illinois
Conditions
Anesthesia, Local, Pain, Postoperative
Interventions
Short-term ON-Q, Short-term ON-Q, Long-term ON-Q, Long-term ON-Q
Device · Drug
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Orlando, Florida
Conditions
Osteoarthritis
Interventions
Active Device (Torino II), Sham Device (Torino II)
Device
Lead sponsor
Center for Joint Surgery and Sports Medicine, Maryland
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2010
U.S. locations
1
States / cities
Hagerstown, Maryland
Conditions
Arthrofibrosis of Knee
Interventions
Losartan
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Conditions
Joint Replacement Surgery
Interventions
Normal Saline 10 mL Injection
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
Not listed
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Not listed Not applicable Interventional Accepts healthy volunteers

Comparing Exparel & Ropivacaine for Pain Relief in Total Knee Arthroplasty

NCT02607579
Conditions
Knee Osteoarthritis
Interventions
Exparel, Ropivacaine
Drug
Lead sponsor
Monmouth Medical Center
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Long Branch, New Jersey
Conditions
Total Knee Arthroplasty (Postoperative Pain), Total Hip Arthroplasty (Postoperative Pain)
Interventions
Transcranial Direct Current Stimulation, Cognitive-Behavioral (CB) intervention
Device · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 90 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Conditions
Infection
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Total Knee Arthroplasty
Interventions
Fixed bearing total knee arthroplasty, Rotating platform total knee arthroplasty
Device
Lead sponsor
William Hopkinson
Other
Eligibility
Not listed
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2021
U.S. locations
1
States / cities
Maywood, Illinois
Conditions
Osteoarthritis of the Knee
Interventions
Instrument
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 75 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
St Louis, Missouri
Completed No phase listed Observational Accepts healthy volunteers Results available

Optimized Loading Response by JOURNEY II BCS Knee Increases Daily Physical Activity and Functions

NCT02335710
Conditions
Knee Injuries
Interventions
Journey II BCS TKA
Device
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
40 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
3
States / cities
Knoxville, Tennessee
Completed Phase 4 Interventional Results available

Antibiotic Elution in Total Knee Arthroplasty

NCT03928522
Conditions
Total Knee Replacement
Interventions
hand mixed vancomycin, hand mixed tobramycin, pre-mixed tobramycin
Drug · Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
Arthropathy of Knee Joint
Interventions
Vancomycin
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Phoenix, Arizona
Withdrawn Not applicable Interventional Accepts healthy volunteers

A Randomized Controlled Trial for Partial Knee Arthroplasty

NCT05037734
Conditions
Degenerative Joint Disease of Knee, Osteoarthritis, Traumatic Arthritis, Varus Deformity, Knee Pain Chronic
Interventions
Persona Partial Knee System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
Not listed
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
Jackson, Mississippi
Conditions
Total Knee Arthroplasty, Osteoarthritis
Interventions
Physical Activity Behavior Intervention, Attention Control
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 85 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Adductor Canal Block Versus Femoral Nerve Block for Total Knee Arthroplasty

NCT03133481
Conditions
Arthropathy of Knee
Interventions
Adductor Canal Nerve Block, Femoral Nerve Block
Procedure · Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 100 Years
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Osteoarthritis
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
40 Years to 90 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Completed Not applicable Interventional

Blood Flow Restriction Exercise Study

NCT02868021
Conditions
Osteoarthritis, Knee
Interventions
Strength testing, Short Physical Performance Battery (SPPB), Six-minute walk (SMW), Numerical pain scale, Self-assessed function, Muscle biopsies, Determination of 1 Repetition Maximum (1-RM), Blood flow restriction exercise, Borg CR10 scale
Device · Behavioral · Procedure
Lead sponsor
University of Florida
Other
Eligibility
55 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Completed Not applicable Interventional

The Effect of a Psychosensory Therapy

NCT02765932
Conditions
Joint Replacement Surgery
Interventions
Dummy Movements, Psychosensory Therapy
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York