- Conditions
- Rupture of Anterior Cruciate Ligament, Osteoarthritis
- Interventions
- Not listed
- Lead sponsor
- Vanderbilt University
- Other
- Eligibility
- 14 Years to 55 Years
- Enrollment
- 432 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2025
- U.S. locations
- 4
- States / cities
- St Louis, Missouri • Cleveland, Ohio • Columbus, Ohio + 1 more
Search Results
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Showing 1–24
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- Conditions
- Infection of Total Knee Joint Prosthesis
- Interventions
- Bactisure
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2019
- U.S. locations
- 5
- States / cities
- Los Angeles, California • Lexington, Kentucky • Louisville, Kentucky + 2 more
- Conditions
- Post-op Pain
- Interventions
- Morphine PCA started at the end of surgery, 1 Percocet 1/325mg every 4 hours; may receive a second Percocet if needed., For the 30ml ropivacaine the intervention would be the subject can request extra pain medication which would be Percocet and/or morphine PCA.
- Drug
- Lead sponsor
- Loma Linda University
- Other
- Eligibility
- 18 Years to 99 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2017
- U.S. locations
- 1
- States / cities
- Loma Linda, California
- Conditions
- Arthroplasty, Replacement, Knee
- Interventions
- YM150, Warfarin
- Drug
- Lead sponsor
- Astellas Pharma Inc
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 685 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2009
- U.S. locations
- 44
- States / cities
- Mobile, Alabama • Phoenix, Arizona • Tuscon, Arizona + 35 more
- Conditions
- Articular Cartilage
- Interventions
- Carticel (autologous cultured chondrocyte) implantation
- Biological
- Lead sponsor
- Vericel Corporation
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 126 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2000 – 2005
- U.S. locations
- 25
- States / cities
- Los Angeles, California • San Diego, California • Santa Monica, California + 22 more
- Conditions
- Acute Postoperative Pain, Surgery
- Interventions
- continuous peripheral nerve block with OnQ pump, single injection nerve block
- Device · Drug
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 40 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- La Jolla, California
- Conditions
- Post-operative Pain
- Interventions
- Liposome Bupivacaine, Bupivacaine HCl
- Drug
- Lead sponsor
- Northwell Health
- Other
- Eligibility
- 18 Years to 74 Years
- Enrollment
- 65 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 1
- States / cities
- Valley Stream, New York
- Conditions
- VTE Prophylaxis With Anticoagulation After Total Knee Replacement Surgery
- Interventions
- JNJ-64179375 0.3 mg/kg, JNJ-64179375 0.6 mg/kg, JNJ-64179375 1.2 mg/kg, JNJ-64179375 (Dose to be Determined), JNJ-64179375 A mg/kg, JNJ-64179375 B mg/kg, JNJ-64179375 C mg/kg, JNJ-64179375 D mg/kg, Placebo JNJ-64179375, Apixaban placebo, Apixaban 2.5 mg
- Drug
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Eligibility
- 50 Years and older
- Enrollment
- 308 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2018
- U.S. locations
- 7
- States / cities
- Phoenix, Arizona • Torrance, California • Englewood, Colorado + 4 more
- Conditions
- Wound Heal, Wound of Skin
- Interventions
- Factorial Assignment
- Other
- Lead sponsor
- University of California, Davis
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2024
- U.S. locations
- 1
- States / cities
- Sacramento, California
- Conditions
- Surgical Wound, Bilateral Total Knee Arthroplasty, Wounds and Injuries, Joint Diseases, Musculoskeletal Diseases, Edema Leg, Joint Pain, Arthritis Knee
- Interventions
- Closed Incision Negative Pressure Therapy (ciNPT), Standard Silver-containing Dressing
- Device
- Lead sponsor
- Solventum US LLC
- Industry
- Eligibility
- 22 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2022
- U.S. locations
- 6
- States / cities
- Annapolis, Maryland • Baltimore, Maryland • Columbia, Maryland + 3 more
- Conditions
- Wound Healing, Scarring
- Interventions
- Topical calcium glycerophosphate lotion
- Other
- Lead sponsor
- AkPharma Inc.
- Industry
- Eligibility
- 45 Years to 75 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2010
- U.S. locations
- 1
- States / cities
- Egg Harbor, New Jersey
- Conditions
- Osteoarthritis, Knee
- Interventions
- MISHA Knee System, Non-Surgical Treatment
- Device · Other
- Lead sponsor
- Moximed
- Industry
- Eligibility
- Not listed
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2030
- U.S. locations
- 9
- States / cities
- Davis, California • Oceanside, California • Sacramento, California + 6 more
- Conditions
- Knee Pain, Knee Osteoarthritis
- Interventions
- Not listed
- Lead sponsor
- Penn State University
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2010
- U.S. locations
- 1
- States / cities
- Hershey, Pennsylvania
- Conditions
- Anterior Cruciate Ligament Injury
- Interventions
- Operant Conditioning, Control, Single Pulse Transcranial Magnetic Stimulation
- Behavioral · Device
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years to 45 Years
- Enrollment
- 11 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2025
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Anterior Cruciate Ligament Rupture
- Interventions
- Initial graft tension during ACL reconstruction surgery
- Procedure
- Lead sponsor
- Rhode Island Hospital
- Other
- Eligibility
- 15 Years to 50 Years
- Enrollment
- 168 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2004 – 2024
- U.S. locations
- 2
- States / cities
- Providence, Rhode Island
- Conditions
- Degenerative Arthritis of Knee
- Interventions
- VISIONAIRE Total Knee Arthroplasty, Standard Total Knee Arthroplasty
- Other
- Lead sponsor
- Smith & Nephew, Inc.
- Industry
- Eligibility
- Not listed
- Enrollment
- 134 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 6
- States / cities
- Park Ridge, Illinois • Springfield, Illinois • St Louis, Missouri + 3 more
- Conditions
- Pain
- Interventions
- Ofirmev, Caldolor
- Drug
- Lead sponsor
- Anita Gupta
- Other
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 78 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2014
- U.S. locations
- 1
- States / cities
- Philadelphia, Pennsylvania
- Conditions
- ACL Injury, Anterior Cruciate Ligament Injuries
- Interventions
- Video-Based Intervention, Classroom-Based Intervention
- Behavioral
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 15 Years to 65 Years
- Enrollment
- 105 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 1
- States / cities
- Phoenix, Arizona
- Conditions
- Wound of Knee, Wound of Hip
- Interventions
- Single-Use Negative Pressure Wound Therapy, Standard postsurgical dressings
- Device
- Lead sponsor
- University of Missouri-Columbia
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 526 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 1
- States / cities
- Columbia, Missouri
- Conditions
- Total Knee Replacement
- Interventions
- Reaming with Synthes RIA (Reamer-Irrigator-Aspirator), Reaming with conventional reamer
- Procedure
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Anterior Cruciate Ligament Injuries
- Interventions
- Opiate Sparing, Opiate Based
- Drug
- Lead sponsor
- Campbell Clinic
- Other
- Eligibility
- 14 Years to 85 Years
- Enrollment
- 56 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 1
- States / cities
- Memphis, Tennessee
- Conditions
- Chronic Pain
- Interventions
- Observational
- Other
- Lead sponsor
- Wake Forest University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 55 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2017
- U.S. locations
- 1
- States / cities
- Winston-Salem, North Carolina
- Conditions
- Osteoarthritis, Pain
- Interventions
- Placebo, Fulranumab 1 mg, Fulranumab 3 mg, Celecoxib 100 mg, Celecoxib 100 mg Matching Placebo
- Drug
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 111 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2016
- U.S. locations
- 32
- States / cities
- Glendale, Arizona • Phoenix, Arizona • Tucson, Arizona + 29 more
- Conditions
- Knee Osteoarthritis, Musculoskeletal Disease, Surgery
- Interventions
- PAI, PAI + steroid, PAI + zilretta
- Drug
- Lead sponsor
- Walter Reed National Military Medical Center
- Federal
- Eligibility
- 18 Years and older
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2027
- U.S. locations
- 1
- States / cities
- Bethesda, Maryland