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ClinicalTrials.gov public records Last synced Nov 5, 2026, 1:55 PM EST

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Showing 1–24 of 211 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Knee and Hip Clear all

Conditions: Prosthesis Related Infections
Interventions: [124I]FIAU; Radiation
Lead sponsor: BioMed Valley Discoveries, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2013
U.S. locations: 3
States / cities: Little Rock, Arkansas • Baltimore, Maryland • Lake Success, New York

Conditions: Prosthetic-joint Infection
Interventions: Culturelle Digestive Daily Probiotic Capsule; Dietary Supplement
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 90 Years
Enrollment: 152 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Osteoarthritis, Knee, Osteoarthritis, Hip, Osteo Arthritis Shoulders, Synovitis of Knee, Synovitis/Tenosynovitis - Hip, Synovitis, Pain, Chronic
Interventions: Shoulder/Hip/Knee Embolization with Embozene Microspheres; Device
Lead sponsor: Palo Alto Veterans Institute for Research; Other
Eligibility: 25 Years to 80 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Osteoarthritis, Knee, Osteoarthritis, Hip, Avascular Necrosis, Rheumatoid Arthritis
Interventions: POPOP (preoperative patient optimization program), SOC (standard of care); Other
Lead sponsor: University of Arkansas; Other
Eligibility: 18 Years to 80 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Anemia, Arthritis, Total Knee Arthroplasty, Total Hip Arthroplasty
Interventions: Conventional Oral TXA (Tranexamic Acid), Multi-Dose Oral TXA (Tranexamic Acid); Drug
Lead sponsor: Rush University Medical Center; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Postoperative Recovery
Interventions: GRF6021, Placebo; Biological · Other
Lead sponsor: Alkahest, Inc.; Industry
Eligibility: 50 Years to 85 Years
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Prosthetic Joint Infections
Interventions: [124I]FIAU; Radiation
Lead sponsor: BioMed Valley Discoveries, Inc; Industry
Eligibility: 18 Years and older
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2013
U.S. locations: 10
States / cities: Mobile, Alabama • Tucson, Arizona • Little Rock, Arkansas + 7 more

Conditions: Allergic Contact Dermatitis, Osteoarthritis, Hip, Osteoarthritis, Knee
Interventions: Sylke Adhesive Dressing, Exofin Skin Glue, Suture Strip Plus; Procedure
Lead sponsor: West Virginia University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 600 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: Morgantown, West Virginia

Conditions: Prosthetic Joint Infection, Debridement With Prosthesis Retention, Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee, Suture
Interventions: VICRYL™ Plus (Coated VICRYL™ Plus Antibacterial), Polydioxanone (PDS™ II ) Sterile Synthetic Absorbable Surgical Suture-Monofilament; Device
Lead sponsor: University of Miami; Other
Eligibility: 18 Years to 89 Years
Enrollment: 142 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Hyperglycemia
Interventions: Metformin, Placebo; Drug · Other
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years to 99 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Osteoarthritis
Interventions: DVD Decision Aid, Internet Based Decision Aid; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 18 Years and older
Enrollment: 155 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2014
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Venous Thromboembolism
Interventions: Not listed
Lead sponsor: Medical Compression Systems; Industry
Eligibility: 18 Years and older
Enrollment: 411 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011
U.S. locations: 10
States / cities: Little Rock, Alaska • La Jolla, California • Menlo Park, California + 7 more

Conditions: Osteoarthritis, Knee, Osteoarthritis, Hip
Interventions: REGN475, Placebo; Drug
Lead sponsor: Regeneron Pharmaceuticals; Industry
Eligibility: 40 Years to 80 Years
Enrollment: 421 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 72
States / cities: Birmingham, Alabama • Mobile, Alabama • Chandler, Arizona + 69 more

Conditions: Knee Pain, Hip Pain, Ankle Pain, Lumbopelvic Pain
Interventions: lumbosacral joint manipulation, lumbar passive range of motion, No active intervention; Other
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years to 50 Years
Enrollment: 106 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Knee Osteoarthritis, Hip Osteoarthritis
Interventions: Kaia hip and knee pain application, Treatment as usual; Behavioral · Other
Lead sponsor: Kaia Health Software; Industry
Eligibility: 22 Years to 75 Years
Enrollment: 192 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021
U.S. locations: 1
States / cities: Stamford, Connecticut

Conditions: Patellofemoral Osteoarthritis
Interventions: Supervised exercise program; Other
Lead sponsor: University of the Sciences in Philadelphia; Other
Eligibility: 35 Years to 70 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2015
U.S. locations: 2
States / cities: Philadelphia, Pennsylvania

Conditions: Total Knee Arthroplasty (Postoperative Pain), Total Hip Arthroplasty(Postoperative Pain)
Interventions: 4 Real sessions of Transcranial Direct Current Stimulation, 2 Real Sessions of Transcranial Direct Current Stimulation, 1 Real Session of Transcranial Direct Current Stimulation, Sham Transcranial Direct Current Stimulation; Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 19 Years to 90 Years
Enrollment: 119 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: Diabetes Mellitus, Steroid Diabetes, Shoulder Osteoarthritis, Knee Osteoarthritis, Adhesive Capsulitis, Hip Osteoarthritis
Interventions: Not listed
Lead sponsor: Duke University; Other
Eligibility: 40 Years to 75 Years
Enrollment: 38 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Joint Replacement Surgery
Interventions: Dummy Movements, Psychosensory Therapy; Procedure
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: New York, New York

Conditions: Post-Op Complication
Interventions: Telemedicine; Other
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Hip Fracture, Osteoarthritis, Femur Head Necrosis
Interventions: Essential amino acid supplement, Ketoconazole, Placebo; Drug
Lead sponsor: University of Arkansas; Other
Eligibility: 30 Years to 80 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Arthroscopic Knee Repair, Arthroscopic Hip Repair
Interventions: Methadone group, Placebo; Drug
Lead sponsor: Keck School of Medicine of USC; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Osteoarthritis, Knee, Osteoarthritis, Hip
Interventions: Fasinumab, Naproxen, Fasinumab-matching placebo, Naproxen-matching placebo; Drug
Lead sponsor: Regeneron Pharmaceuticals; Industry
Eligibility: 18 Years and older
Enrollment: 3,307 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 58
States / cities: Mesa, Arizona • Phoenix, Arizona • Tucson, Arizona + 50 more

Conditions: Postoperative Pain
Interventions: Q8003 (morphine sulfate and oxycodone hydrochloride), Low dose Q8003 (morphine sulfate and oxycodone hydrochloride), Percocet (oxycodone and acetaminophen); Drug
Lead sponsor: QRxPharma Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009
U.S. locations: 4
States / cities: Birmingham, Alabama • Phoenix, Arizona • Royal Oak, Michigan + 1 more

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Biodistribution and Dosimetry Evaluation of [124I]FIAU

The Effect of Peri-Operative Adjunctive Probiotics on Immunological Markers in Cases of Prosthetic Joint Infection of the Hip and Knee

Perfusion MRI-targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee

Impact of a POPOP on Preoperative Health, Eligibility, and Clinical & Patient-Reported Outcomes in TJA

Single Versus Multi-Dose Oral Tranexamic Acid in Patients at High Risk for Blood Transfusion After Total Joint Arthroplasty

A Study to Evaluate the Effect of GRF6021 on Postoperative Recovery Following Primary Hip or Knee Arthroplasty

[124I]FIAU PET-CT Scanning in Patients With Pain in a Prosthetic Knee or Hip Joint

Rate of Allergic Contact Dermatitis and Cosmetic Outcomes

Antibiotic-coated Braided Suture Study

Metformin Use in Patients Undergoing Total Joint Replacement Surgery

Evaluation of DVD and Internet Decision Aids for Hip and Knee Osteoarthritis: Focus on Health Literacy

Multicenter Registry for Effectiveness Analysis of ActiveCare+S.F.T® Mobile Compression Device for Thrombosis Prevention in Hip and Knee Arthroplasty

Study of REGN475 in Patients With Pain Due to Osteoarthritis of the Knee or Hip

Effects of Lumbosacral Joint Mobilization/Manipulation on Lower Extremity Muscle Neuromuscular Response

The Kaia Hip and Knee Pain Intervention for Self-management of the Pain in Patients With Osteoarthritis.

Effect of Hip and Core Muscle Strengthening for Patellofemoral Osteoarthritis: A Feasibility Study

Dose Dependent Effects of tDCS on Post-Operative Pain

Effect of Corticosteroid Injections on Blood Glucose

The Effect of a Psychosensory Therapy

Tele-monitoring of Post Join Arthroplasty Outcomes: A Feasibility Study

Effectiveness of Two Types of Treatment in Restoring Muscle After Hip or Knee Surgery

PO Methadone Ortho Outpatient

A Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Naproxen for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip

Pilot Study of the Efficacy and Safety of Q8003 in Patients Who Have Undergone Total Knee Arthroplasty or Total Hip Arthroplasty