Independent directory Public ClinicalTrials.gov records United States
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Showing 145–168 of 210 matching trials from the live ClinicalTrials.gov search.
Conditions
Prosthetic Joint Infection
Interventions
Phage Therapy, Two-Stage Exchange Arthroplasty
Biological · Procedure
Lead sponsor
Adaptive Phage Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Conditions
Osteoarthritis
Interventions
CR845 0.25 mg, CR845 0.50 mg, CR845 1 mg, CR845 5 mg
Drug
Lead sponsor
Cara Therapeutics, Inc.
Industry
Eligibility
25 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
5
States / cities
Omaha, Nebraska • Las Vegas, Nevada • Greensboro, North Carolina + 2 more
Terminated Phase 3 Interventional Results available

Tanezumab In Osteoarthritis Of The Hip Or Knee

NCT00985621
Conditions
Osteoarthritis
Interventions
tanezumab 10 mg, tanezumab 5 mg, oxycodone, placebo
Biological · Drug · Other
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 75 Years
Enrollment
614 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
66
States / cities
Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 54 more
Conditions
Patellofemoral Pain Syndrome
Interventions
Lumbopelvic Manipulation, Passive lumbar spine flexion and extension
Other
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 50 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Dallas, Texas
Conditions
Osteoarthritis, Knee
Interventions
OM1 Dell Shared Decision Making Tool, Education material from OM1 Dell Shared Decision Making Tool
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
45 Years to 89 Years
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Austin, Texas
Conditions
Osteoarthritis
Interventions
Cell injection
Procedure
Lead sponsor
Texas Plastic Surgery
Industry
Eligibility
25 Years to 85 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
San Antonio, Texas
Not listed Not applicable Interventional Accepts healthy volunteers

Prophylaxis Against DVTs After Primary Hip and Knee Replacement Surgery

NCT00767559
Conditions
Pulmonary Embolism
Interventions
warfarin, Fondaparinux:
Drug
Lead sponsor
The New England Baptist Hospital
Other
Eligibility
20 Years and older
Enrollment
330 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome
Interventions
Lumbar Spine Manipulation, Lumbar Spine Manipulation Placebo
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 65 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Conditions
Patellofemoral Pain Syndrome
Interventions
Triplanar Rotary Resistance
Other
Lead sponsor
High Point University
Other
Eligibility
18 Years and older · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
High Point, North Carolina
Conditions
Osteoarthritis of the Knee or Hip
Interventions
Fasinumab, Placebo
Drug
Lead sponsor
Regeneron Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
5,331 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
50
States / cities
Birmingham, Alabama • Chandler, Arizona • Glendale, Arizona + 44 more
Conditions
Diabetes Mellitus, Type 2, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Interventions
Dexcom G6 Pro Continuous Glucose Monitor (CGM)
Device
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Stony Brook, New York
Conditions
Arthropathy of Knee, Osteo Arthritis Knee, Osteonecrosis, Meditation, Knee Osteoarthritis, Knee Disease, Knee Injuries, Opioid Use, Opioid Dependence, Opioid Use Disorder
Interventions
Mindful meditation
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Hip Osteoarthritis, Knee Osteoarthritis
Interventions
Brief interactive decision aid, Long video decision aid
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts • Newton, Massachusetts
Conditions
Chronic Low Back Pain, Osteoarthritis
Interventions
Fasinumab, Placebo
Drug
Lead sponsor
Regeneron Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
56
States / cities
Phoenix, Arizona • Tucson, Arizona • Anaheim, California + 47 more
Conditions
ACL Injury, Hip Injuries
Interventions
Physical Therapy, Monitored Work-out, Moxy Oxygen Sensor Device
Procedure · Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
14 Years to 30 Years
Enrollment
226 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Avon, Ohio • Cleveland, Ohio
Recruiting No phase listed Observational Accepts healthy volunteers

HealthEast Community Hip and Knee Replacement Registry

NCT02692092
Conditions
Bone Fracture
Interventions
Not listed
Lead sponsor
HealthEast Care System
Other
Eligibility
18 Years and older
Enrollment
200,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1991 – 2091
U.S. locations
1
States / cities
Saint Paul, Minnesota
Conditions
Musculoskeletal Pain, Musculoskeletal Injury
Interventions
clinical examination, MRI
Diagnostic Test · Other
Lead sponsor
High Point University
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
High Point, North Carolina
Completed Not applicable Interventional Results available

Evaluating Advantages of Prevena After Hip and Knee Arthroplasty

NCT01854138
Conditions
Infection of Total Hip Joint Prosthesis
Interventions
Prevena Incision Management System
Device
Lead sponsor
ProMedica Health System
Other
Eligibility
18 Years to 85 Years
Enrollment
248 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Toledo, Ohio
Conditions
Chronic Pain
Interventions
Tramadol HCl ER
Drug
Lead sponsor
Bausch Health Americas, Inc.
Industry
Eligibility
18 Years to 74 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
1
States / cities
Duncansville, Pennsylvania
Conditions
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Interventions
JointCOACH
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
446 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Recruiting Not applicable Interventional Accepts healthy volunteers

Preoperative Oral Hydration in the Ambulatory Arthroplasty Population

NCT05520593
Conditions
Same-day Discharge, Length of Stay
Interventions
Complex Carbohydrate Drink
Dietary Supplement
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 75 Years
Enrollment
312 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
New York, New York
Conditions
Pulmonary Embolism
Interventions
Blood sample
Genetic
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 70 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2035
U.S. locations
1
States / cities
Los Angeles, California
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip, Chronic Low Back Pain
Interventions
COV155
Drug
Lead sponsor
Mallinckrodt
Industry
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
34
States / cities
Anaheim, California • Lomita, California • Santa Ana, California + 24 more
Conditions
Osteoarthritis, Pain
Interventions
Placebo, Fulranumab 1 mg, Fulranumab 3 mg, Celecoxib 100 mg, Celecoxib 100 mg Matching Placebo
Drug
Lead sponsor
Janssen Research & Development, LLC
Industry
Eligibility
18 Years to 99 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
32
States / cities
Glendale, Arizona • Phoenix, Arizona • Tucson, Arizona + 29 more