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ClinicalTrials.gov public records Last synced Oct 22, 2026, 1:47 AM EDT

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Showing 409–432 of 919 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: LASER Clear all
Completed Not applicable Interventional

Study of Light Treatment and Laser Treatment for Melasma

NCT00509977
View directory record Official record
Conditions
Melasma
Interventions
Light Treatment, Laser Treatment
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 75 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 3, 2021 · Synced Oct 22, 2026, 1:47 AM EDT
Completed Not applicable Interventional

Patient Comfort Using Green vs. Yellow Pan Retinal Photocoagulation

NCT02995629
View directory record Official record
Conditions
Proliferative Diabetic Retinopathy - High Risk
Interventions
laser indirect ophthalmoscopy pan retinal photocoagulation
Procedure
Lead sponsor
Wills Eye
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 16, 2016 · Synced Oct 22, 2026, 1:47 AM EDT
Withdrawn Not applicable Interventional

Clinical Evaluation of 755nm Alexandrite Laser Versus Nanosecond 755nm Alexandrite

NCT01811017
View directory record Official record
Conditions
Tattoos
Interventions
755nm Alexandrite Laser
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 85 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 5, 2014 · Synced Oct 22, 2026, 1:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of Low Level Laser Therapy to Reduce Body Circumference in Obese Individuals

NCT01821352
View directory record Official record
Conditions
Obesity
Interventions
Erchonia Obesity Laser, Placebo Laser
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years to 65 Years
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
2
States / cities
Noblesville, Indiana • Bloomfield Hills, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 11, 2015 · Synced Oct 22, 2026, 1:47 AM EDT
Terminated Not applicable Interventional Results available

Bronchoscopic Laser Ablation of Peripheral Lung Tumors

NCT03707925
View directory record Official record
Conditions
Lung Carcinoid Tumor, Lung Non-Small Cell Carcinoma, Metastatic Lung Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8
Interventions
Cone-Beam Computed Tomography, Conventional Surgery, Laser Ablation
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 16, 2023 · Synced Oct 22, 2026, 1:47 AM EDT
Completed No phase listed Observational

Laser Spectroscopy of Breast Tissue Through a Needle Device

NCT00918788
View directory record Official record
Conditions
Breast Cancer
Interventions
biologic sample preservation procedure, immunohistochemistry staining method, light microscopy, medical chart review, histopathologic examination, needle biopsy, spectroscopy
Other · Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 22, 2013 · Synced Oct 22, 2026, 1:47 AM EDT
Recruiting No phase listed Observational

Filter Initial & Long Term Evaluation After Placement and Retrieval Registry

NCT01158482
View directory record Official record
Conditions
Venous Thromboembolism
Interventions
IVC Filter Placement or Retrieval
Procedure
Lead sponsor
Stanford University
Other
Eligibility
Not listed
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2030
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Oct 22, 2026, 1:47 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Single-Blind Study Assessing the Use of a Topical Antioxidant With A Series of Laser Procedures to Reduce Sebum Production

NCT06376110
View directory record Official record
Conditions
Acne
Interventions
Topical Antioxidant Serum, AviClear Laser
Drug · Device
Lead sponsor
Austin Institute for Clinical Research
Network
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Pflugerville, Texas
Source: ClinicalTrials.gov public record
Updated May 16, 2024 · Synced Oct 22, 2026, 1:47 AM EDT
Completed Not applicable Interventional

Pilot Study on Laser Ablation of Symptomatic Benign Thyroid Masses

NCT00615537
View directory record Official record
Conditions
Thyroid Nodule, Thyroid Cancer, Thyroid Neoplasms, Nodular Goiter
Interventions
Laser Ablation of Thyroid Nodule
Procedure
Lead sponsor
BioTex, Inc.
Industry
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 5, 2011 · Synced Oct 22, 2026, 1:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Centration of Intraocular Lens With Two Settings for Capsulorhexis With Femtosecond Laser

NCT02315456
View directory record Official record
Conditions
Capsulorhexis
Interventions
capsulorhexis
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
45 Years to 95 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 10, 2020 · Synced Oct 22, 2026, 1:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Investigation of the Role of 905-nm Laser Light in the Delay of Muscle Fatigue

NCT03461731
View directory record Official record
Conditions
Muscle Fatigue
Interventions
Control, 800 nm laser, combination laser, 905 nm laser
Device
Lead sponsor
College of Charleston
Other
Eligibility
18 Years to 25 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 12, 2018 · Synced Oct 22, 2026, 1:47 AM EDT
Terminated Not applicable Interventional

Efficacy Study of AuroLase Therapy in Subjects With Primary and/or Metastatic Lung Tumors

NCT01679470
View directory record Official record
Conditions
Primary or Metastatic Lung Tumors
Interventions
AuroLase Therapy
Device
Lead sponsor
Nanospectra Biosciences, Inc.
Industry
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 3, 2016 · Synced Oct 22, 2026, 1:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

TR-987 vs. Placebo Following Fractionated CO2 Laser Resurfacing of the Chest

NCT02681224
View directory record Official record
Conditions
Exposure Laser
Interventions
TR987 Gel with Silon Bandage, TR987 without Silon Bandage, Placebo Gel with Silon Bandage, Placebo Gel without Silon Bandage
Other
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 1, 2017 · Synced Oct 22, 2026, 1:47 AM EDT
Completed Not applicable Interventional Results available

Volumetric Laser Endomicroscopy With Intelligent Real-time Image Segmentation (IRIS)

NCT03814824
View directory record Official record
Conditions
Barrett's Esophagus Without Dysplasia, Barrett's Esophagus With Dysplasia, Barrett's Esophagus With Low Grade Dysplasia, Barrett's Esophagus With High Grade Dysplasia, Barrett's Esophagus With Dysplasia, Unspecified
Interventions
IRIS (Intelligent real-time image segmentation), VLE (Volumetric laser endomicroscopy)
Diagnostic Test
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
3
States / cities
Scottsdale, Arizona • Rochester, Minnesota • Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Oct 7, 2022 · Synced Oct 22, 2026, 1:47 AM EDT
Completed Phase 2 Interventional Results available

Non-cutting Laser Therapy in the Treatment of Acne

NCT00113425
View directory record Official record
Conditions
Acne Vulgaris
Interventions
V-Beam laser, Candela Corp., 595 nm wavelength
Device
Lead sponsor
University of Michigan
Other
Eligibility
15 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 18, 2016 · Synced Oct 22, 2026, 1:47 AM EDT
Terminated No phase listed Observational

Holmium Laser Ablation of the Prostate (HoLAP) Versus KTP Laser Vaporization of the Prostate

NCT00169767
View directory record Official record
Conditions
Benign Prostatic Hyperplasia
Interventions
Comparison study between KTP and HoLAP for BPH
Other
Lead sponsor
Indiana Kidney Stone Institute
Other
Eligibility
18 Years and older · Male only
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
3
States / cities
Indianapolis, Indiana • Westland, Michigan • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 25, 2008 · Synced Oct 22, 2026, 1:47 AM EDT
Completed Not applicable Interventional Results available

Evaluation of 1440nm Laser Assisted Selective Photothermolysis for Treatment of Axillary Hyperhidrosis

NCT02100072
View directory record Official record
Conditions
Hyperhidrosis
Interventions
Nd:YAG 1440 nm laser
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 8, 2021 · Synced Oct 22, 2026, 1:47 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Clinical Study to Evaluate the Improvement in Hair Loss in Skin of Color Treated With Fractional Non-Ablative Laser

NCT06885112
View directory record Official record
Conditions
Hair Loss
Interventions
FoLix treatment for improving the scalp hair appearance
Device
Lead sponsor
Lumenis Be Ltd.
Industry
Eligibility
21 Years to 55 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 2, 2026 · Synced Oct 22, 2026, 1:47 AM EDT
Recruiting Not applicable Interventional

REMASTer: REcurrent Brain Metastases After SRS Trial

NCT05124912
View directory record Official record
Conditions
Brain Metastases, Radiation Necrosis, Recurrent Tumor, Recurrent Metastases
Interventions
Radiation Therapy, Steroid Therapy, Laser Interstitial Thermal Therapy
Procedure · Drug
Lead sponsor
Monteris Medical
Industry
Eligibility
18 Years and older
Enrollment
261 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
9
States / cities
Los Angeles, California • Chicago, Illinois • Baltimore, Maryland + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2026 · Synced Oct 22, 2026, 1:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Performance of the SOLTIVE Laser System for Laser Lithotripsy in Kidney or Ureteral Stones

NCT04556201
View directory record Official record
Conditions
Kidney Stone, Ureteral Stone
Interventions
SOLTIVE™ Premium SuperPulsed Laser Fiber System
Device
Lead sponsor
Olympus Corporation of the Americas
Industry
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
5
States / cities
Phoenix, Arizona • Loma Linda, California • Kansas City, Kansas + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Oct 22, 2026, 1:47 AM EDT
Recruiting Not applicable Interventional

Light Therapy Device for Neonatal Intraventricular Hemorrhage Grade 3 and 4

NCT06797219
View directory record Official record
Conditions
Intraventricular Hemorrhage of Prematurity, Hydrocephalus
Interventions
Low Level Laser Therapy for Intraventricular Hemorrhage of Prematurity
Device
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
0 Days to 1 Month
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 22, 2025 · Synced Oct 22, 2026, 1:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study of the Effects of the Pulsed-dye Laser at 585nm and 595nm to Treat Post-operative Scars on Suture-removal Day

NCT00482144
View directory record Official record
Conditions
Cicatrix, Scars
Interventions
PDL 450 microseconds, PDL 1.5 milliseconds
Procedure
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2008
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 28, 2016 · Synced Oct 22, 2026, 1:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Acoustic Enhancer Research on Laser Lithotripsy (AEROLITH)

NCT04563039
View directory record Official record
Conditions
Urinary Stones
Interventions
Ureteroscopy Laser Lithotripsy (URS-LL) with Acoustic Enhancer, Standard Ureteroscopic Laser Lithotripsy
Device
Lead sponsor
Avvio Medical
Industry
Eligibility
18 Years to 75 Years
Enrollment
196 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
23
States / cities
Birmingham, Alabama • Tucson, Arizona • Little Rock, Arkansas + 20 more
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Oct 22, 2026, 1:47 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Fractional CO2 Laser for the Treatment of Lichen Planus Pigmentosus

NCT05170308
View directory record Official record
Conditions
Lichen Planus Pigmentosus
Interventions
CO2 fractional laser
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Aug 2, 2022 · Synced Oct 22, 2026, 1:47 AM EDT