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ClinicalTrials.gov public records Last synced Oct 23, 2026, 11:01 AM EDT

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Showing 649–672 of 919 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: LASER Clear all
Completed Phase 2 Interventional Results available

Ranibizumab and Peripheral Scatter Laser in Patients With Diabetic Macular Edema and Peripheral Nonperfusion

NCT00815360
View directory record Official record
Conditions
Diabetic Macular Edema
Interventions
intravitreal injection of ranibizumab, peripheral laser, intravitreal injection of triamcinolone acetonide, macular laser
Drug · Procedure
Lead sponsor
Retina Associates of Florida, P.A.
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 5, 2015 · Synced Oct 23, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study of Nutritional Supplementation in Altering Ecchymosis, Erythema and Health Outcomes Associated With Aesthetic Procedures

NCT01919359
View directory record Official record
Conditions
Ecchymosis and Erythema Commonly Associated With Soft Tissue Filler Injections
Interventions
Multizyme Cellular Vitality Cyruta Plus SHEP
Dietary Supplement
Lead sponsor
DeNova Research
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 1, 2018 · Synced Oct 23, 2026, 11:01 AM EDT
Completed Not applicable Interventional

Laser Versus Mechanical Lithotripsy of Bile Duct Stones

NCT01759979
View directory record Official record
Conditions
Choledocholithiasis
Interventions
Laser and mechanical lithotripsy, Mechanical Lithotripsy
Procedure
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 31, 2017 · Synced Oct 23, 2026, 11:01 AM EDT
Completed Not applicable Interventional Results available

Combined Photodynamic and Pulsed Dye Laser Treatment of Port Wine Stains

NCT00556946
View directory record Official record
Conditions
Port Wine Stains
Interventions
Combined Photodynamic & Pulsed Dye Laser Treatment
Drug
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2014
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 21, 2022 · Synced Oct 23, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Fractionated 1927nm Laser for Hyperpigmentation in Fitzpatrick Skin Phototypes V and VI

NCT05493280
View directory record Official record
Conditions
Hyperpigmentation
Interventions
MOXI
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Oct 23, 2026, 11:01 AM EDT
Not listed Not applicable Interventional

Clinical Study to Evaluate Alexandrite Laser for the Treatment of Acne Scars

NCT04807179
View directory record Official record
Conditions
Acne Scars
Interventions
Experimental: RF Device Arm
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Los Angeles, California • New York, New York
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Oct 23, 2026, 11:01 AM EDT
Recruiting Not applicable Interventional

LITT Followed by Hypofractionated RT for Newly Diagnosed Gliomas (GCC 20138)

NCT04699773
View directory record Official record
Conditions
Glioma, Glioblastoma, Brain Tumor
Interventions
LITT, Hypofractionated Radiation Therapy
Procedure · Radiation
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
5
States / cities
Baltimore, Maryland • Bel Air, Maryland • Columbia, Maryland + 1 more
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 23, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Prospective, Open-Label, Single-Center, Non-Comparative Study to Assess the Use of Pixel CO2 Laser System (FemiLift) in the Treatment of Vulvovaginal Atrophy (VVA) in Postmenopausal Female Subjects

NCT02747641
View directory record Official record
Conditions
Atrophy, Vaginal Atrophy, Genital Diseases, Female
Interventions
Pixel CO2 Laser System
Procedure
Lead sponsor
Alma Lasers Inc.
Industry
Eligibility
35 Years to 70 Years · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Nov 21, 2017 · Synced Oct 23, 2026, 11:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Safety & Efficacy Evaluation of a Radiofrequency & Laser/Light System for Improvement of Skin Texture

NCT01597323
View directory record Official record
Conditions
Skin Texture Irregularities, Facial Skin Wrinkles
Interventions
Not listed
Lead sponsor
Candela Corporation
Industry
Eligibility
35 Years to 60 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
3
States / cities
Boca Raton, Florida • Hunt Valley, Maryland • Great Neck, New York
Source: ClinicalTrials.gov public record
Updated Dec 6, 2019 · Synced Oct 23, 2026, 11:01 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Comparison of Compounded Topical Anesthetics

NCT06569537
View directory record Official record
Conditions
Procedural Pain
Interventions
Lidocaine topical, BLT
Drug
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 23, 2026, 11:01 AM EDT
Completed Phase 3 Interventional Results available

Clobetasol Propionate Versus Fractionated Carbon Dioxide Laser for the Treatment of Lichen Sclerosus

NCT02573883
View directory record Official record
Conditions
Vulvar Lichen Sclerosus
Interventions
Fractionated Carbon Dioxide Laser, Clobetasol Propionate 0.05% ointment
Device · Drug
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 12, 2021 · Synced Oct 23, 2026, 11:01 AM EDT
Not listed Phase 1Phase 2 Interventional

Electrical Acupuncture and Laser Therapy for Low Back Pain

NCT00779818
View directory record Official record
Conditions
Chronic Low Back Pain
Interventions
Electrical acupuncture, Laser
Device
Lead sponsor
Logan College of Chiropractic
Other
Eligibility
20 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Chesterfield, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 24, 2008 · Synced Oct 23, 2026, 11:01 AM EDT
Completed Not applicable Interventional Results available

Safety and Effectiveness of the CLEAR + BRILLIANT TOUCH(R) Diode Laser 1440-nm and 1927-nm Combination Wavelength Treatment

NCT05027282
View directory record Official record
Conditions
Photoaging
Interventions
CLEAR + BRILLIANT TOUCH(R) 1440-nm and 1927-nm handpieces.
Device
Lead sponsor
Bausch Health Americas, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 22, 2023 · Synced Oct 23, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Combination Versus Laser Treatment Only

NCT03661697
View directory record Official record
Conditions
Photoaging
Interventions
Laser Therapy, Basic Skin Care Regimen, Lytera
Device · Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 23, 2026, 11:01 AM EDT
Terminated Not applicable Interventional

Laser Dosage in MicroPulse TransScleral CycloPhotocoagulation

NCT04709679
View directory record Official record
Conditions
Glaucoma
Interventions
MicroPulse TransScleral CycloPhotoCoagulation
Procedure
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 89 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jul 1, 2022 · Synced Oct 23, 2026, 11:01 AM EDT
Completed Not applicable Interventional

Laser Atherectomy Versus Angioplasty for the Treatment of Critical Limb Ischemia

NCT01579123
View directory record Official record
Conditions
Critical Limb Ischemia
Interventions
Angioplasty, Laser atherectomy
Procedure
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
3
States / cities
Dallas, Texas • Plano, Texas
Source: ClinicalTrials.gov public record
Updated Jan 19, 2018 · Synced Oct 23, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Radiofrequency and Hybrid Fractional Laser for Vaginal Rejuvenation

NCT03316950
View directory record Official record
Conditions
Vaginal Atrophy
Interventions
IntraGen RF, DiVA, Placebo (DIVA/IntraGen combined)
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
40 Years to 65 Years · Female only
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 4, 2023 · Synced Oct 23, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Conventional Photorefractive Keratectomy (PRK) in U.S. Army Personnel, Substudy of: Initial Evaluation of Excimer Laser Keratorefractive Surgery in U.S. Army Personnel

NCT00412568
View directory record Official record
Conditions
Myopia
Interventions
Photorefractive Keratectomy (PRK)
Procedure
Lead sponsor
Walter Reed Army Medical Center
Federal
Eligibility
21 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 1, 2008 · Synced Oct 23, 2026, 11:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cranial Laser Reflex Technique for Hamstring Function

NCT03044106
View directory record Official record
Conditions
Hamstring Injury, Muscle Tone Increased, Muscle Pain, Muscle Weakness
Interventions
CLRT
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 12, 2019 · Synced Oct 23, 2026, 11:01 AM EDT
Not yet recruiting Not applicable Interventional

MoDi Twin Placental Imaging

NCT07667647
View directory record Official record
Conditions
Monochorionic Diamniotic Placenta, Monochorial Monoamniotic Placenta, Monochorionic Twins, Ultrasound Doppler, Ultrasound, Pregnancy, Twin Pregnancy, Monochorionic, Twin Twin Transfusion Syndrome
Interventions
Verasonics Vantage 256 Ultrasound
Device
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 23, 2026, 11:01 AM EDT
Recruiting No phase listed Observational

Filter Initial & Long Term Evaluation After Placement and Retrieval Registry

NCT01158482
View directory record Official record
Conditions
Venous Thromboembolism
Interventions
IVC Filter Placement or Retrieval
Procedure
Lead sponsor
Stanford University
Other
Eligibility
Not listed
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2030
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 26, 2025 · Synced Oct 23, 2026, 11:01 AM EDT
Completed Not applicable Interventional

Confocal Laser Probe to Treat Barrett's Esophagus

NCT02852525
View directory record Official record
Conditions
Barrett's Esophagus
Interventions
Confocal laser endomicroscopy (pCLE)
Device
Lead sponsor
Virendra Joshi
Other
Eligibility
19 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
2
States / cities
Kenner, Louisiana • New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Aug 2, 2016 · Synced Oct 23, 2026, 11:01 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

GenTeal in Perioperative Treatment of Laser Assisted in Situ Keratomileusis LASIK Patients

NCT00598689
View directory record Official record
Conditions
Corneal Epithelium Defect
Interventions
0.3% hypromellose
Drug
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 60 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 7, 2016 · Synced Oct 23, 2026, 11:01 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Comparative Study of Two Topical Anesthetics Prior to Fractional Nonablative Laser Treatment of the Face

NCT04523961
View directory record Official record
Conditions
Anesthesia, Local, Photodamaged Skin, Topical and Infiltration Anesthetic Toxicity
Interventions
2.5 g of lidocaine 23% / tetracaine 7% ointment without occlusion, 7.5 g lidocaine 2.5%/ prilocaine 2.5% cream with occlusion
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 23, 2026, 11:01 AM EDT