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ClinicalTrials.gov public records Last synced Oct 23, 2026, 9:35 PM EDT

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Showing 817–840 of 919 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: LASER Clear all
Not listed Not applicable Interventional

NdYag Laser for Acne Keloidalis Nuchae

NCT00757315
View directory record Official record
Conditions
Acne Keloidalis Nuchae, NdYag Laser, AKN, Acne Keloidalis, AK, Dermatitis Papillaris Capillitii, Folliculitis Keloidalis Nuchae, Sycosis Nuchae, Acne Keloid, Keloidal Folliculitis, Lichen Keloidalis Nuchae, Folliculitis Nuchae Scleroticans, Sycosis Framboesiformis
Interventions
NdYag Laser(hair removal laser) plus topical corticosteroid, Topical corticosteroid alone
Device · Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 29, 2013 · Synced Oct 23, 2026, 9:35 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Dynamic Light Scattering Device (DLS) Study of Age-Related Changes in the Lens and Cataracts

NCT00007215
View directory record Official record
Conditions
Cataract, Healthy
Interventions
Not listed
Lead sponsor
National Eye Institute (NEI)
NIH
Eligibility
Not listed
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 23, 2026, 9:35 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Effects of Low-Level Laser Stimulation With and Without Fear Extinction Training

NCT02926352
View directory record Official record
Conditions
Phobias, Claustrophobia, Social Phobia
Interventions
Extinction Training, Low-Level Laser Therapy, Sham Low-Level Laser Therapy
Behavioral · Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 28, 2022 · Synced Oct 23, 2026, 9:35 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluate the Performance of the PicoWayTM Picosecond Fractional Laser for Wrinkles Reduction

NCT02600104
View directory record Official record
Conditions
Unwanted Wrinkles
Interventions
PicoWayTM
Device
Lead sponsor
Syneron Medical
Industry
Eligibility
18 Years to 75 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
4
States / cities
Chicago, Illinois • New York, New York • Ardmore, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Oct 23, 2026, 9:35 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Panoptix Trifocal Lens in Post Refractive Myopic Laser Vision Correction Surgery

NCT04698278
View directory record Official record
Conditions
Cataract, Refractive Errors
Interventions
PanOptix Trifocal Intraocular Lens
Device
Lead sponsor
Parkhurst NuVision Clinical Research LLC
Other
Eligibility
22 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 17, 2021 · Synced Oct 23, 2026, 9:35 PM EDT
Completed No phase listed Observational Results available

Laser Ablation After Stereotactic Radiosurgery

NCT01651078
View directory record Official record
Conditions
Metastatic Brain Tumors, Progression, Radiation Necrosis, Quality of Life
Interventions
Not listed
Lead sponsor
Monteris Medical
Industry
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
7
States / cities
New Haven, Connecticut • Kansas City, Kansas • St Louis, Missouri + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2024 · Synced Oct 23, 2026, 9:35 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Compression and CO2 Laser for Leg Wounds

NCT04198454
View directory record Official record
Conditions
Wound Healing
Interventions
Compression bandages, Standard wound dressings, Fractional ablative carbon dioxide laser
Other · Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 23, 2026, 9:35 PM EDT
Completed Not applicable Interventional

Ureteroscopy With High-powered Holmium:Yag Laser Lithotripsy With and Moses On or Moses Off

NCT06346483
View directory record Official record
Conditions
Kidney Stone, Ureteral Stone
Interventions
Dusting without Moses 2.0 Modulation, Dusting with Moses 2.0 Modulation, Moses 2.0 Modulation
Procedure · Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 90 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 23, 2026, 9:35 PM EDT
Completed Not applicable Interventional Results available

Picosure Alexandrite Laser for the Treatment of Unwanted Tattoos

NCT02110095
View directory record Official record
Conditions
Unwanted Tattoos
Interventions
Picosure Laser System
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 11, 2020 · Synced Oct 23, 2026, 9:35 PM EDT
Not listed Not applicable Interventional

Effectiveness of Laser Hair Removal in Pilonidal Disease

NCT03276065
View directory record Official record
Conditions
Pilonidal Disease
Interventions
Laser depilation, Standard of care hair depilation
Device · Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
11 Years to 21 Years
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 25, 2022 · Synced Oct 23, 2026, 9:35 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Transvaginal Low-level Laser Therapy to Improve Pelvic Pain and Sexual Function in Patients with Endometriosis.

NCT05540353
View directory record Official record
Conditions
Endometriosis, Dyspareunia, Pelvic Pain
Interventions
Transvaginal photobiomodulation, Sham therapy
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
6
States / cities
Washington D.C., District of Columbia • Mitchellville, Maryland • Rockville, Maryland + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2025 · Synced Oct 23, 2026, 9:35 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

In-vivo Analysis of a Fractional CO2 Laser System (eMatrixCO2) Intended for Treatment of Soft Tissue

NCT01026662
View directory record Official record
Conditions
Abdominoplasty
Interventions
Ablation and skin resurfacing, eMatrixCO2
Procedure · Device
Lead sponsor
Syneron Medical
Industry
Eligibility
20 Years to 60 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2009
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 2, 2014 · Synced Oct 23, 2026, 9:35 PM EDT
Completed Phase 4 Interventional

Evaluation of Outcomes Using the AMO Advanced Customvue™ iLasik Procedure

NCT01061294
View directory record Official record
Conditions
Vision Correction
Interventions
Advanced CustomVue™ iLASIK procedure, WaveScan WaveFront® System, STAR S4 IR™ Excimer Laser System and IntraLase™ FS System
Procedure · Device
Lead sponsor
Innovative Medical
Industry
Eligibility
21 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 13, 2011 · Synced Oct 23, 2026, 9:35 PM EDT
Completed Not applicable Interventional Results available

Volumetric Laser Endomicroscopy With Intelligent Real-time Image Segmentation (IRIS)

NCT03814824
View directory record Official record
Conditions
Barrett's Esophagus Without Dysplasia, Barrett's Esophagus With Dysplasia, Barrett's Esophagus With Low Grade Dysplasia, Barrett's Esophagus With High Grade Dysplasia, Barrett's Esophagus With Dysplasia, Unspecified
Interventions
IRIS (Intelligent real-time image segmentation), VLE (Volumetric laser endomicroscopy)
Diagnostic Test
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
3
States / cities
Scottsdale, Arizona • Rochester, Minnesota • Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Oct 7, 2022 · Synced Oct 23, 2026, 9:35 PM EDT
Terminated Not applicable Interventional Results available

Topo-guided LASIK and Photorefractive Keratectomy vs Wavefront LASIK and Photorefractive Keratectomy

NCT03075176
View directory record Official record
Conditions
Surgery, Myopia
Interventions
Wavefront optimized LASIK, Wavefront optimized Photorefractive Keratectomy, Topography-guided LASIK, Topography-guided Photorefractive Keratectomy
Device
Lead sponsor
University of Utah
Other
Eligibility
21 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Jul 17, 2023 · Synced Oct 23, 2026, 9:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With Fractional Ablative CO2 Laser for Facial Rejuvenation

NCT06366503
View directory record Official record
Conditions
Photoaging, Wrinkle, Skin Laxity
Interventions
Fractional Ablative CO2 Laser, Facial Cleanser, Facial Moisturizer, Sunscreen, Basic Ointment
Procedure · Other
Lead sponsor
Revision Skincare
Industry
Eligibility
35 Years to 65 Years · Female only
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Blue Ash, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 3, 2025 · Synced Oct 23, 2026, 9:35 PM EDT
Completed Not applicable Interventional

Early Apical Release vs Classic Holmium Laser Enucleation of the Prostate: Randomized Controlled Trial Comparing Post-Operative Incontinence Rates and Surgical Outcomes

NCT04566588
View directory record Official record
Conditions
Benign Prostatic Hyperplasia
Interventions
EAR HoLEP, Classic HoLEP
Procedure
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older · Male only
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Oct 23, 2026, 9:35 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Laser 360iQ: Optimal Light-laser Combination Therapy

NCT04519723
View directory record Official record
Conditions
Photodamage
Interventions
Assess the safety and efficacy of light-laser therapy using the Harmony XL and Dye-VL (500-600nm), Q-Switched 1064nm, Er:YAG 2940nm modules in combination .
Device
Lead sponsor
Alma Lasers Inc.
Industry
Eligibility
35 Years to 60 Years · Female only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Edina, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 20, 2020 · Synced Oct 23, 2026, 9:35 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Fractionated 1927-nm Non Ablative Thulium Laser in Treating Post Inflammatory Hyperpigmentation

NCT06149780
View directory record Official record
Conditions
Healthy
Interventions
Patients treated with laser
Device
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Oct 23, 2026, 9:35 PM EDT
Recruiting No phase listed Observational

Evaluation of Cataract Surgery Outcomes in Patients With Prior Laser Vision Correction Implanted With the CT LUCIA Lens

NCT07084545
View directory record Official record
Conditions
Postoperative Visual Outcomes Following Cataract Surgery in Patients With Prior Myopic Corneal Laser Vision Correction
Interventions
CT LUCIA 621P Intraocular Lens Implantation
Device
Lead sponsor
Carl Zeiss Meditec AG
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Sugar Land, Texas • Lynchburg, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Oct 23, 2026, 9:35 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

A Pilot Study to Evaluate Multi-Spectral and Laser Speckle Imaging and Multiphoton Microscopy During Vascular Occlusion

NCT01484730
View directory record Official record
Conditions
Abnormal Vascular Flow
Interventions
Multi-Spectral and Laser Speckle Imaging
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2028
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 23, 2026, 9:35 PM EDT
Recruiting No phase listed Observational

Ability of Modulated Imaging and Laser Speckle Imaging to Determine Burn Wound Severity and Healing Potential

NCT01166893
View directory record Official record
Conditions
Skin Burn Multiple
Interventions
Modulated Imaging and Laser Speckle Imaging
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
1 Minute and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2030
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 23, 2026, 9:35 PM EDT
Completed Phase 3 Interventional Results available

Confocal Endomicroscopy for Barrett's Esophagus

NCT00487695
View directory record Official record
Conditions
Barrett's Esophagus, Esophageal Adenocarcinoma
Interventions
confocal laser endomicroscopy (CLE), standard endoscopy (EGD)
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 22, 2021 · Synced Oct 23, 2026, 9:35 PM EDT
Completed Not applicable Interventional Results available

Evaluating the Safety and Efficacy of the Pico Laser With a Specialized Lens Array for the Treatment of Wrinkles

NCT02091102
View directory record Official record
Conditions
Wrinkles
Interventions
755nm Alexandrite Laser
Device
Lead sponsor
Cynosure, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Virginia Beach, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 25, 2020 · Synced Oct 23, 2026, 9:35 PM EDT