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ClinicalTrials.gov public records Last synced Oct 24, 2026, 1:34 AM EDT

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Showing 865–888 of 919 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: LASER Clear all
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Cognitive Enhancement Through Transcranial Laser Therapy

NCT02851173
View directory record Official record
Conditions
Healthy Participants, Mild Cognitive Impairment
Interventions
LLLT, Placebo
Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
45 Years and older
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 4, 2023 · Synced Oct 24, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Micropulse Laser Trabeculoplasty (MLT) Versus Selective Laser Trabeculoplasty (SLT) for Treatment of Open Angle Glaucoma

NCT01956942
View directory record Official record
Conditions
Open Angle Glaucoma
Interventions
Micropulse Laser Trabeculoplasty, Selective Laser Trabeculoplasty
Device
Lead sponsor
David Belyea
Other
Eligibility
Not listed
Enrollment
81 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 13, 2023 · Synced Oct 24, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Multi-Wavelength Laser Tattoo Removal Pivotal Study

NCT02935660
View directory record Official record
Conditions
Tattoo Removal
Interventions
enLighten Laser
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Brisbane, California • Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 26, 2023 · Synced Oct 24, 2026, 1:34 AM EDT
Completed Not applicable Interventional

Photobiomodulation to Demonstrate Safety and Reduce the Incidence of Oral Mucositis in Adult Head & Neck Cancer Patients

NCT03972527
View directory record Official record
Conditions
Oral Mucositis (Ulcerative), Oral Mucositis (Ulcerative) Due to Radiation, Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy, Head and Neck Cancer
Interventions
Photobiomodulation, Routine Oral Care and Analgesia
Device · Other
Lead sponsor
MuReva Phototherapy Inc.
Industry
Eligibility
22 Years and older
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
12
States / cities
Birmingham, Alabama • Long Beach, California • Miami, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Oct 24, 2026, 1:34 AM EDT
Completed No phase listed Observational

Comparison of Femtosecond Laser Assisted Cataract Surgery to Conventional Phacoemulsification Cataract Surgery

NCT02096627
View directory record Official record
Conditions
Cataract
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 90 Years
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 16, 2018 · Synced Oct 24, 2026, 1:34 AM EDT
Recruiting Not applicable Interventional

Confocal Laser Endomicroscopy VERification

NCT06079970
View directory record Official record
Conditions
Lung Cancer, Lung Neoplasm Malignant, Carcinoma, Non-Small-Cell Lung, Neoplasm of Lung
Interventions
Neelde Based Confocal Laser Endomicroscopy, Conventional diagnostic bronchoscopy
Device · Procedure
Lead sponsor
Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC)
Other
Eligibility
18 Years and older
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 24, 2026, 1:34 AM EDT
Completed Phase 4 Interventional

Skin Blood Flow Changes Using Laser Doppler Imager for Assessment of Pain and Analgesia in Newborn Infants

NCT00694174
View directory record Official record
Conditions
Procedural Pain
Interventions
sucrose 24% oral solution, sterile water
Drug
Lead sponsor
Children's Hospital of Michigan
Other
Eligibility
1 Day to 7 Days
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 10, 2008 · Synced Oct 24, 2026, 1:34 AM EDT
Completed Phase 2 Interventional

Efficacy Study of Lucentis in the Treatment of Diabetic Macular Edema

NCT00387582
View directory record Official record
Conditions
Diabetic Retinopathy, Diabetic Macular Edema
Interventions
Ranibizumab (Lucentis), Argon Laser
Drug · Procedure
Lead sponsor
Rocky Mountain Retina Consultants
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 6, 2014 · Synced Oct 24, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Topical Vitamin K, Vitamin K and Retinol, and Arnica on Post-Laser Bruising

NCT00363038
View directory record Official record
Conditions
Ecchymosis
Interventions
Petrolatum United States Pharmacopeia (USP), Vitamin K and retinol ointment, Arnica ointment, Vitamin K ointment
Drug
Lead sponsor
Northwestern University
Other
Eligibility
20 Years to 60 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 3, 2021 · Synced Oct 24, 2026, 1:34 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Effect of Contact Lens Wear on Immune Cell Density and Morphology of the Ocular Surface

NCT01250925
View directory record Official record
Conditions
Myopia, Refractive Error
Interventions
ReNu MultiPlus® MultiPurpose Solution, OPTI-FREE® RepleniSH®, Clear Care®
Drug
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
2
States / cities
Iowa City, Iowa • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Oct 24, 2026, 1:34 AM EDT
Withdrawn Not applicable Interventional

A Study to See if Low Level Laser Light Therapy (LLLT) Can Improve the Condition of Nonalcoholic Steatohepatitis (NASH)

NCT03163810
View directory record Official record
Conditions
Nonalcoholic Steatohepatitis
Interventions
Erchonia Verju Laser, Erchonia EVRL Laser
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 28, 2020 · Synced Oct 24, 2026, 1:34 AM EDT
Terminated Not applicable Interventional Results available

Staging of Superficial EAC Using VLE

NCT03385343
View directory record Official record
Conditions
Esophageal Cancer
Interventions
VLE imaging for staging EAC
Diagnostic Test
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 95 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 9, 2023 · Synced Oct 24, 2026, 1:34 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effect of Microneedling, Bimatoprost and Excimer in Vitiligo Treatment

NCT04738149
View directory record Official record
Conditions
Vitiligo
Interventions
Bimatoprost, Excimer laser, Microneedling with a dermaroller
Drug · Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 5, 2022 · Synced Oct 24, 2026, 1:34 AM EDT
Completed Phase 1Phase 2 Interventional

Laser Interstitial Thermotherapy (LITT) Combined With Checkpoint Inhibitor for Recurrent GBM (RGBM)

NCT03277638
View directory record Official record
Conditions
Glioblastoma, Adult
Interventions
Pembrolizumab at 7 days prior, Pembrolizumab at 14 days post, Pembrolizumab at 35 days post, Laser Interstitial Thermotherapy
Drug · Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 24, 2026, 1:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Optical Coherence Tomography Guided Laser Treatment of Basal Cell Carcinoma

NCT04744935
View directory record Official record
Conditions
Basal Cell Carcinoma, Superficial Basal Cell Carcinoma, Nodular Basal Cell Carcinoma
Interventions
1064 nm long-pulse Nd:YAG laser
Device
Lead sponsor
Christopher Zachary
Other
Eligibility
18 Years to 99 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Oct 21, 2026 · Synced Oct 24, 2026, 1:34 AM EDT
Completed Not applicable Interventional

A Single Center Randomized Controlled Trial Assessing Pain and Quality of Life Following Surgery

NCT01355926
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
Flexible Fiber-based CO2 Laser, Quality of Life forms, electrocautery resection and quality of life forms
Other
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2021
U.S. locations
4
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 15, 2021 · Synced Oct 24, 2026, 1:34 AM EDT
Withdrawn Not applicable Interventional

MRI-Guided LITT for Treatment Metastatic Brain Tumors

NCT01736722
View directory record Official record
Conditions
Brain Tumor
Interventions
Visualase®
Device
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
19 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 17, 2018 · Synced Oct 24, 2026, 1:34 AM EDT
Completed Not applicable Interventional Results available

Dermatosis Papulosa Nigra

NCT00710203
View directory record Official record
Conditions
Facial Dermatoses, Seborrheic Keratoses
Interventions
Pulsed dye laser, Curettage, Electrodesiccation, No treatment
Device · Procedure · Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Oct 24, 2026, 1:34 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Comparison Study on Topical Anesthetic Agents (LMX4 and BLT) Prior to Fractional Skin Resurfacing

NCT01842373
View directory record Official record
Conditions
Pain
Interventions
LMX4, BLT
Drug
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2013
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 25, 2017 · Synced Oct 24, 2026, 1:34 AM EDT
Recruiting Not applicable Interventional

Differences in Postoperative Symptoms With Four Ureteral Stents

NCT06083051
View directory record Official record
Conditions
Urinary Stone
Interventions
6Fr Percuflex ureteral stents, 6Fr Tria ureteral stents, 4.8Fr Tria ureteral stents, 4.8Fr Percuflex ureteral stents
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 89 Years
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 24, 2026, 1:34 AM EDT
Withdrawn No phase listed Observational

Intraoperative Optical Imaging of Brain Function

NCT00632437
View directory record Official record
Conditions
Brain Tumor
Interventions
Speckle-Contrast Imaging
Procedure
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2012 · Synced Oct 24, 2026, 1:34 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Efficacy Study of GLYC-101 to Evaluate Outcomes After Laser Ablation

NCT00792688
View directory record Official record
Conditions
Wounds
Interventions
GLYC-101 Gel (0.1%), GLYC-101 Gel (1.0%), GLYC-101 Placebo
Drug
Lead sponsor
TR Therapeutics
Industry
Eligibility
25 Years to 70 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Beverly Hills, California
Source: ClinicalTrials.gov public record
Updated Oct 28, 2021 · Synced Oct 24, 2026, 1:34 AM EDT
Completed Not applicable Interventional Results available

Ultrasonic Aspiration Versus CO2 Laser Ablation for the Treatment of Vulvar Intraepithelial Neoplasia

NCT02875561
View directory record Official record
Conditions
Vulvar Intraepithelial Neoplasia (VIN)
Interventions
Sonopet Ultrasonic Aspirator, CO2 Laser Ablation
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years · Female only
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
2
States / cities
Aurora, Colorado • Norman, Oklahoma
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 24, 2026, 1:34 AM EDT
Recruiting Not applicable Interventional

Pilot Study for OCT Guided In Vivo Laser Capture Microdissection for Assessing the Prognosis of Barrett's Esophagus

NCT03830801
View directory record Official record
Conditions
Barrett Esophagus
Interventions
IVLCM tethered capsule
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Oct 24, 2026, 1:34 AM EDT