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ClinicalTrials.gov public records Last synced Oct 22, 2026, 2:12 AM EDT

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Showing 1–24 of 46 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: LGBTQ Clear all
Completed Not applicable Interventional Accepts healthy volunteers

SGM Evidenced-Based Mental Healthcare Implementation

NCT05890404
View directory record Official record
Conditions
CBT, LGBTQ
Interventions
LGBTQ-Affirmative CBT Training: Materials Only, LGBTQ-Affirmative CBT Training: Direct Training, LGBTQ-Affirmative CBT Training: Local Supervision
Behavioral
Lead sponsor
Yale University
Other
Eligibility
15 Years and older
Enrollment
1,379 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Oct 22, 2026, 2:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility of a Multi-Level School Intervention for LGBTQ Youth

NCT04041414
View directory record Official record
Conditions
Sexual Minority Stress Experiences Among LGBTQ Youth
Interventions
Proud & Empowered!
Other
Lead sponsor
University of Southern California
Other
Eligibility
12 Years to 20 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
4
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated Jul 28, 2021 · Synced Oct 22, 2026, 2:12 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Efficacy of a Multi-level School Intervention for LGBTQ Youth

NCT05541406
View directory record Official record
Conditions
Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior, Sexual Minority Stress, Suicidality, Substance Use, Bullying, Harassment
Interventions
Proud & Empowered, Control Group
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years to 20 Years
Enrollment
228 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
23
States / cities
El Monte, California • Glendale, California • Inglewood, California + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 22, 2026, 2:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lakota Family Acceptance Project

NCT07326748
View directory record Official record
Conditions
LGBTQ, Racial Disparities, Family Relationships, Minority Stress, Depression, Anxiety, Drug Use, Teen Dating Violence, Sexual Risk Reduction
Interventions
Adapted Lakota Family Acceptance Program
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
13 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
2
States / cities
Pine Ridge, South Dakota • Rapid City, South Dakota
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 22, 2026, 2:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Game Plan for PrEP

NCT04973267
View directory record Official record
Conditions
Human Immunodeficiency Virus Exposure, Alcohol; Harmful Use
Interventions
Game Plan for PrEP, Attention-Matched Control Lifestyle Habits Videos
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Male only
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Aug 28, 2024 · Synced Oct 22, 2026, 2:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Impact of the IN•Clued Curriculum: An LGBTQ Sex ed Program

NCT04494477
View directory record Official record
Conditions
Teen Pregnancy, STD Prevention
Interventions
The IN•clued program
Behavioral
Lead sponsor
Philliber Research & Evaluation
Other
Eligibility
14 Years and older
Enrollment
1,401 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Accord, New York
Source: ClinicalTrials.gov public record
Updated Jul 31, 2020 · Synced Oct 22, 2026, 2:12 AM EDT
Completed Not applicable Interventional

Refining Novel Culturally Tailored Behavioral Weight Loss Treatment Components for Sexual Minority Women With Obesity

NCT05036187
View directory record Official record
Conditions
Obesity
Interventions
Behavioral Weight Loss Intervention, Minority Stress Intervention, Negative Body Image Intervention, Social Support Intervention
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 2, 2023 · Synced Oct 22, 2026, 2:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Supporting Trans Affirmation, Relationships, and Sex, Phase 3

NCT06001307
View directory record Official record
Conditions
HIV, Violence, Gender-Based, Violence, Domestic, Risk Reduction Behavior
Interventions
Program STARS (Supporting Trans Affirmation, relationships, and Sex), Relaxation and Stress Reduction
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Male only
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Oct 22, 2026, 2:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Social Media Anti-Vaping Messages to Reduce ENDS Use Among Sexual and Gender Minority Teens

NCT06308081
View directory record Official record
Conditions
Vaping, Adolescent Behavior, Communication Research
Interventions
Tailored
Other
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
13 Years to 20 Years
Enrollment
1,155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 14, 2026 · Synced Oct 22, 2026, 2:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Culturally Targeted & Individually Tailored Smoking Cessation Study: LGBT Smokers

NCT01633567
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Culturally Targeted Cessation Program, Non-Targeted Cessation Program
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 65 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 4, 2017 · Synced Oct 22, 2026, 2:12 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Brief Single-Session Body Neutrality Program for LGBTQ+ Adults in Central Alabama

NCT07621081
View directory record Official record
Conditions
Body Image
Interventions
Single session body neutrality program
Behavioral
Lead sponsor
Auburn University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 22, 2026, 2:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

PLANTS Pilot Trial

NCT05897827
View directory record Official record
Conditions
Alcohol Drinking, Social Acceptance, Depressive Symptoms, Bullying
Interventions
PLANTS, EMAILS
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 4, 2025 · Synced Oct 22, 2026, 2:12 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Family Acceptance Project Online (Pilot RCT)

NCT06839859
View directory record Official record
Conditions
LGBTQ, Racial Disparities, Family Relationships, Minority Stress, Depression, Anxiety, Drug Use, Teen Dating Violence, Sexual Risk Reduction
Interventions
Family Acceptance Project - Online
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years and older
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Oct 22, 2026, 2:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project QueST 2023: Queer Survivors of Trauma

NCT05569915
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Drinking Heavy
Interventions
Trauma Expressive Writing, Stigma Expressive Writing, Control
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Mar 20, 2026 · Synced Oct 22, 2026, 2:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Developing an Online Mindfulness-based Intervention to Reduce Minority Stress and HIV Risk Among Young Adult MSM

NCT05540652
View directory record Official record
Conditions
HIV, Minority Stress, Mental Health Wellness 1
Interventions
Mindfulness-Based Queer Resilience (MBQR)
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 34 Years · Male only
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Oct 22, 2026, 2:12 AM EDT
Recruiting Phase 3 Interventional

Affirmative Family and Individual Psychotherapy for Sexual and Gender Minority Adults and Their Nonaccepting Parents

NCT05766592
View directory record Official record
Conditions
Mental Health Issue, Parent-Child Relations
Interventions
LGBTQ-affirmative CBT, ABFT-SGM
Behavioral
Lead sponsor
Yale University
Other
Eligibility
20 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Oct 22, 2026, 2:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Trial of Online LGBTQ-affirmative Cognitive Behavioral Therapy to Reduce Depression and Associated Health Risks Among Young Adults

NCT04408469
View directory record Official record
Conditions
LGBTQ, Sexual Behavior
Interventions
Online EQuIP, Self-monitoring control
Behavioral
Lead sponsor
Yale University
Other
Eligibility
16 Years to 25 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 3, 2024 · Synced Oct 22, 2026, 2:12 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Minority Stress Counseling for LGBTQ+ Individuals

NCT06614868
View directory record Official record
Conditions
Minority Stress
Interventions
Acceptance and Commitment Therapy, Treatment as Usual (TAU)
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 22, 2026, 2:12 AM EDT
Completed Not applicable Interventional Results available

SmokefreeSGM, A Text-based Smoking Cessation Feasibility Trial for Sexual and Gender Minority Groups

NCT05645354
View directory record Official record
Conditions
Smoking Cessation
Interventions
SmokefreeSGM, SmokefreeTXT
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 17, 2025 · Synced Oct 22, 2026, 2:12 AM EDT
Completed Not applicable Interventional

Evaluating the Efficacy of the Parent Support Program

NCT04531761
View directory record Official record
Conditions
Prejudice, Gender Identity, Knowledge, Attitudes, Practice
Interventions
Parent Support Program
Behavioral
Lead sponsor
Palo Alto University
Other
Eligibility
18 Years and older
Enrollment
570 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 22, 2026, 2:12 AM EDT
Recruiting Not applicable Interventional

Optimizing an Online Behavioral Weight Loss Intervention and Novel Culturally Tailored Components for Sexual Minority Women

NCT05775497
View directory record Official record
Conditions
Obesity
Interventions
Behavioral weight loss intervention (Online; Rx Weight Loss), Minority stress intervention, Social support intervention, Negative body image intervention
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 27, 2024 · Synced Oct 22, 2026, 2:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Minnesota Inclusive LTSS for LGBTQ Seniors

NCT05530590
View directory record Official record
Conditions
Alzheimer Disease, Dementia
Interventions
Training to Serve (TTS) in person training, Training to Serve online training (eTTS)
Other
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
761 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 22, 2026, 2:12 AM EDT
Recruiting Not applicable Interventional

Recovery Through Inhibitory Learning, Self-Efficacy Building, Problem Solving, and Community Building

NCT07217795
View directory record Official record
Conditions
Alcohol Use Disorder (AUD), PTSD
Interventions
CBT + expressive writing, Wait-List Control
Behavioral
Lead sponsor
University of Rhode Island
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 9, 2025 · Synced Oct 22, 2026, 2:12 AM EDT
Active, not recruiting Phase 2 Interventional

Improving Mental Health Among the LGBTQ+ Community

NCT05540067
View directory record Official record
Conditions
Anxiety, Depression
Interventions
Acceptance-Based Behavior Therapy (ABBT), Treatment-as-Usual (TAU)
Behavioral · Other
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 22, 2026, 2:12 AM EDT