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Showing 1–24 of 88 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Labor Analgesia Clear all
Completed Not applicable Interventional

Pocket Warming of Epidural Medication

NCT02912078
View directory record Official record
Conditions
Epidural Anesthesia in Labor and Delivery
Interventions
Pocket-warming, Standard of Care Labor Epidural
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
139 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Jul 22, 2026, 4:07 AM EDT
Not listed No phase listed Observational

Sleep Efficiency and Quantification After Labor Epidural Analgesia

NCT02862951
View directory record Official record
Conditions
Pregnancy
Interventions
Not listed
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 10, 2016 · Synced Jul 22, 2026, 4:07 AM EDT
Withdrawn Phase 4 Interventional

Epidural Fentanyl-bupivacaine Versus Clonidine-bupivacaine for Breakthrough Pain in Advanced Labor

NCT00691795
View directory record Official record
Conditions
Labor Pain
Interventions
Clonidine or fentanyl
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 13, 2012 · Synced Jul 22, 2026, 4:07 AM EDT
Terminated Not applicable Interventional Results available

3D Ultrasound-guided Labor Epidural Analgesia in the Morbid Obese Parturient

NCT03405311
View directory record Official record
Conditions
Obesity, Morbid, Pregnancy, Pain
Interventions
Rivanna Accuro 3D Ultrasound Device, Palpation
Device · Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jul 22, 2026, 4:07 AM EDT
Terminated Not applicable Interventional Results available

Do Peanut Shaped Birthing Balls Reduce the Length of Labor in Patients With Epidural Analgesia?

NCT02539563
View directory record Official record
Conditions
Labor
Interventions
peanut shaped birthing ball
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 17, 2022 · Synced Jul 22, 2026, 4:07 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Mu-Opioid Receptor Genetic Polymorphism and Intrathecal Analgesia

NCT00418015
View directory record Official record
Conditions
Labor Pain, Post-cesarean Delivery
Interventions
Blood Draw
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
293 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 13, 2014 · Synced Jul 22, 2026, 4:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Virtual Reality Analgesia in Labor: The VRAIL Pilot Study

NCT02926469
View directory record Official record
Conditions
Labor Pain
Interventions
Virtual Reality
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 31, 2018 · Synced Jul 22, 2026, 4:07 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Nitrous Oxide for External Cephalic Version

NCT03502915
View directory record Official record
Conditions
External Cephalic Version
Interventions
Nitrous Oxide, Placebo
Drug · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 29, 2019 · Synced Jul 22, 2026, 4:07 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Music Use in Parturients Admitted to Labor & Delivery

NCT06969105
View directory record Official record
Conditions
Anxiety, Pain, Patient Satisfaction
Interventions
Music
Other
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jul 22, 2026, 4:07 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Fetal Heart Rate Changes and Labor Neuraxial Analgesia: a Machine Learning Approach

NCT05399979
View directory record Official record
Conditions
Fetal Bradycardia
Interventions
Labor Neuraxial Analgesia
Procedure
Lead sponsor
Augusta University
Other
Eligibility
18 Years and older · Female only
Enrollment
1,077 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 2, 2022 · Synced Jul 22, 2026, 4:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Hypotension Prediction Index to Predict Epidural-labor Analgesia Induced Hypotension

NCT05906368
View directory record Official record
Conditions
Anesthesia, Epidural, Hypotension
Interventions
ClearSight HPI Monitoring system, Standard of Care Blood Pressure Monitoring
Diagnostic Test
Lead sponsor
Grace Lim, MD, MS
Other
Eligibility
18 Years and older · Female only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Jul 22, 2026, 4:07 AM EDT
Not listed Phase 4 Interventional

Intravenous Terbutaline to Facilitate Labor Epidural Catheter Placement

NCT01651962
View directory record Official record
Conditions
Labor Pain
Interventions
Terbutaline, Fentanyl, 0.9% NaCl
Drug
Lead sponsor
Kai Schoenhage
Other
Eligibility
18 Years to 53 Years · Female only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 18, 2015 · Synced Jul 22, 2026, 4:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Extended-Release Liposomal Bupivacaine for Post-Partum Pain Management Following Obstetrical Laceration

NCT03152877
View directory record Official record
Conditions
Pain, Obstetric
Interventions
Bupivacaine Liposome Injectable Product, 0.25% plain bupivacaine
Drug
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 55 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 14, 2019 · Synced Jul 22, 2026, 4:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Timing on Efficacy of Morphine Analgesia After 2-chloroprocaine Anesthesia

NCT00487084
View directory record Official record
Conditions
Labor, Analgesia, Epidural
Interventions
Morphine-CP-saline (MCS), saline-2CP-morphine (SCM), saline-lidocaine-morphine (SLM)
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 13, 2014 · Synced Jul 22, 2026, 4:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neuraxial Versus Systemic Analgesia for Latent Phase Labor Effect on Rate of Operative Delivery

NCT00380978
View directory record Official record
Conditions
Labor Pain, Pregnancy
Interventions
combined spinal epidural analgesia, late analgesia (systemic)
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
1,026 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 13, 2014 · Synced Jul 22, 2026, 4:07 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

The Impact of Needle Manipulation and Accuracy Between Hand Held Automatic and Traditional Ultrasound Device

NCT05909085
View directory record Official record
Conditions
Labor Analgesia
Interventions
Traditional ultrasound, Automated ultrasound
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 14, 2025 · Synced Jul 22, 2026, 4:07 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Management of Postoperative Pain With Preemptive Analgesia in Cesarean Section

NCT02879435
View directory record Official record
Conditions
Labor Pain
Interventions
Bupivacaine, Placebo
Drug · Other
Lead sponsor
Mark Kosanovich
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 24, 2016 · Synced Jul 22, 2026, 4:07 AM EDT
Recruiting Phase 3 Interventional

Ropivacaine and Fentanyl for Labor Epidural Initiation

NCT07076368
View directory record Official record
Conditions
Pregnancy, Labor and Delivery, Labor Analgesia
Interventions
Ropivacaine + Fentanyl
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Jul 22, 2026, 4:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Prenatal Education on Perceptions of Epidural Acceptance

NCT01709591
View directory record Official record
Conditions
Labor Pain
Interventions
Prenatal education
Behavioral
Lead sponsor
Santa Clara Valley Health & Hospital System
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2018
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Aug 10, 2020 · Synced Jul 22, 2026, 4:07 AM EDT
Withdrawn Phase 3 Interventional

Study to Determine Whether the Instillation of 10ml Normal Saline Improves Epidural Analgesia During Labor

NCT01119079
View directory record Official record
Conditions
Parturients
Interventions
Normal Saline, Administration of epidural anesthesia for labor
Other · Procedure
Lead sponsor
University of Medicine and Dentistry of New Jersey
Other
Eligibility
18 Years to 45 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 23, 2015 · Synced Jul 22, 2026, 4:07 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of Analgesic Techniques on Duration of Spontaneously Laboring Patients

NCT01982838
View directory record Official record
Conditions
Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
Interventions
Epidural de novo, CSE
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
129 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 10, 2014 · Synced Jul 22, 2026, 4:07 AM EDT
Completed Phase 4 Interventional Results available

Comparison of Epidural Fentanyl and Clonidine for Breakthrough Pain

NCT01846221
View directory record Official record
Conditions
Labor Pain
Interventions
Clonidine, Fentanyl
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 2, 2018 · Synced Jul 22, 2026, 4:07 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers

Postoperative Pain Control & Relief in Neonates

NCT03677830
View directory record Official record
Conditions
Pain, Postoperative, Premature Infant, Opioid Use
Interventions
Acetaminophen, Saline
Drug
Lead sponsor
St. Louis University
Other
Eligibility
Up to 1 Month
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Jul 22, 2026, 4:07 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Effectiveness of Clonidine, Dexmedetomidine, and Fentanyl Adjuncts for Labor Epidural Analgesia

NCT05487196
View directory record Official record
Conditions
Pregnancy Related
Interventions
Clonidine, Dexmedetomidine, Fentanyl, Ropivacaine
Drug
Lead sponsor
Grace Lim, MD, MS
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 26, 2025 · Synced Jul 22, 2026, 4:07 AM EDT