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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Labor Analgesia Clear all
Withdrawn Not applicable Interventional Accepts healthy volunteers

Epidural Loading Prior to Catheter Insertion

NCT02883283
View directory record Official record
Conditions
Administration Methods of Labor Analgesia
Interventions
Epidural loading dose, Epidural catheter, Epidural needle
Procedure · Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 26, 2021 · Synced Jul 22, 2026, 11:57 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Impact of Prophylactic Ephedrine on Fetal Heart Tracing and Uterine Tetanic Contraction After CSE

NCT05873218
View directory record Official record
Conditions
Labor
Interventions
Ephedrine, Normal Saline Placebo
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Jul 22, 2026, 11:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Extended-Release Liposomal Bupivacaine for Post-Partum Pain Management Following Obstetrical Laceration

NCT03152877
View directory record Official record
Conditions
Pain, Obstetric
Interventions
Bupivacaine Liposome Injectable Product, 0.25% plain bupivacaine
Drug
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 55 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 14, 2019 · Synced Jul 22, 2026, 11:57 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Inhaled Nitrous Oxide and Labor Analgesia

NCT01738672
View directory record Official record
Conditions
Labor Pain
Interventions
Inhaled nitrous oxide
Drug
Lead sponsor
Ya'aqov Abrams
Other
Eligibility
14 Years and older · Female only
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 20, 2017 · Synced Jul 22, 2026, 11:57 AM EDT
Withdrawn Phase 4 Interventional

Epidural Fentanyl-bupivacaine Versus Clonidine-bupivacaine for Breakthrough Pain in Advanced Labor

NCT00691795
View directory record Official record
Conditions
Labor Pain
Interventions
Clonidine or fentanyl
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 13, 2012 · Synced Jul 22, 2026, 11:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CSE v. Epidural for Postpartum Depression

NCT03022526
View directory record Official record
Conditions
Depression, Postpartum, Labor Pain
Interventions
CSE, Epidural, Bupivacaine / fentaNYL
Procedure · Drug
Lead sponsor
Grace Lim, MD, MS
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 18, 2020 · Synced Jul 22, 2026, 11:57 AM EDT
Recruiting Phase 2 Interventional

Pain Control for Cervical Ripening Balloon

NCT07268118
View directory record Official record
Conditions
Labor Induction
Interventions
topical vaginal application lidocaine gel
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Jul 22, 2026, 11:57 AM EDT
Not listed Phase 4 Interventional

Intravenous Terbutaline to Facilitate Labor Epidural Catheter Placement

NCT01651962
View directory record Official record
Conditions
Labor Pain
Interventions
Terbutaline, Fentanyl, 0.9% NaCl
Drug
Lead sponsor
Kai Schoenhage
Other
Eligibility
18 Years to 53 Years · Female only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 18, 2015 · Synced Jul 22, 2026, 11:57 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Use of Ultrasound in Obstetric Neuraxial Analgesia and Anesthesia Data Base

NCT01192074
View directory record Official record
Conditions
Pregnancy
Interventions
Ultrasound
Device
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 4, 2016 · Synced Jul 22, 2026, 11:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Does Ultrasound Help With Placement of Labor Analgesia in Pregnant Patients?

NCT02207972
View directory record Official record
Conditions
Pregnancy
Interventions
Use of Ultrasound, No ultrasound used
Device · Procedure
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 48 Years · Female only
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 12, 2018 · Synced Jul 22, 2026, 11:57 AM EDT
Completed No phase listed Observational Results available

Does Maternal Fever During Labor Analgesia Has Any Relationship With Maternal Ventilation?

NCT02339389
View directory record Official record
Conditions
Pregnancy
Interventions
Labor analgesia
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 18, 2018 · Synced Jul 22, 2026, 11:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Association Between Bolus Rate and the Adequacy of Labor Analgesia Using Timed-intermittent Boluses

NCT02340806
View directory record Official record
Conditions
Labor Pain, Obstetric Pain
Interventions
CADD-Solis pump (Smiths Medical)
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 25, 2019 · Synced Jul 22, 2026, 11:57 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Ambulation With Labor Epidural in Obese Women

NCT04504682
View directory record Official record
Conditions
Obesity, Labor Onset and Length Abnormalities
Interventions
Ambulation
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 5, 2023 · Synced Jul 22, 2026, 11:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Timing on Efficacy of Morphine Analgesia After 2-chloroprocaine Anesthesia

NCT00487084
View directory record Official record
Conditions
Labor, Analgesia, Epidural
Interventions
Morphine-CP-saline (MCS), saline-2CP-morphine (SCM), saline-lidocaine-morphine (SLM)
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 13, 2014 · Synced Jul 22, 2026, 11:57 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of Analgesic Techniques on Duration of Labor for Induction Patients

NCT01982851
View directory record Official record
Conditions
Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
Interventions
Epidural de novo, CSE
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 10, 2014 · Synced Jul 22, 2026, 11:57 AM EDT
Completed No phase listed Observational Results available

Patient Education on Labor Analgesia Options

NCT02557555
View directory record Official record
Conditions
Labor Analgesia
Interventions
educational information
Other
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 6, 2019 · Synced Jul 22, 2026, 11:57 AM EDT
Terminated Not applicable Interventional Results available

Do Peanut Shaped Birthing Balls Reduce the Length of Labor in Patients With Epidural Analgesia?

NCT02539563
View directory record Official record
Conditions
Labor
Interventions
peanut shaped birthing ball
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 17, 2022 · Synced Jul 22, 2026, 11:57 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Intracutaneous Sterile Water Injections

NCT01513447
View directory record Official record
Conditions
Labor Pain
Interventions
Intracutaneous injections
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 1, 2015 · Synced Jul 22, 2026, 11:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Dural Puncture Epidural Versus Traditional Lumbar Epidural on Onset of Labor Analgesia

NCT02412969
View directory record Official record
Conditions
Labor Pain, Labor Analgesia
Interventions
Lumbar Epidural, Dural Puncture Epidural
Procedure
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 16, 2016 · Synced Jul 22, 2026, 11:57 AM EDT
Completed Phase 4 Interventional Results available

Comparison of Epidural Fentanyl and Clonidine for Breakthrough Pain

NCT01846221
View directory record Official record
Conditions
Labor Pain
Interventions
Clonidine, Fentanyl
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 2, 2018 · Synced Jul 22, 2026, 11:57 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Goal-directed Labor Epidural Analgesia Maintenance

NCT05255263
View directory record Official record
Conditions
Labor Onset and Length Abnormalities
Interventions
PIEB, CEI
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 13, 2022 · Synced Jul 22, 2026, 11:57 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

EpiFaith Resident Learning Curve Trial

NCT07395622
View directory record Official record
Conditions
Epidural Analgesia, Epidural Analgesia for Labour and Delivery, Learning Curve
Interventions
EpiFaith epidural syringe, Control (glass) syringe
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Jul 22, 2026, 11:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Optimizing Dose of Bupivacaine in Combined Spinal Epidurals To Reduce Side Effects

NCT02159807
View directory record Official record
Conditions
Pregnancy
Interventions
Bupivacaine, Fentanyl
Drug
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 48 Years · Female only
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 2, 2019 · Synced Jul 22, 2026, 11:57 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Does Ultrasound Help Junior Anesthesia Residents With Placement of Labor Analgesia in Pregnant Patients

NCT02747238
View directory record Official record
Conditions
Pregnancy
Interventions
Ultrasound, No ultrasound, Epidural infusion
Device · Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 48 Years · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 14, 2021 · Synced Jul 22, 2026, 11:57 AM EDT