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ClinicalTrials.gov public records Last synced Sep 26, 2026, 10:47 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Labor Analgesia Clear all
Terminated Not applicable Interventional Results available

Do Peanut Shaped Birthing Balls Reduce the Length of Labor in Patients With Epidural Analgesia?

NCT02539563
View directory record Official record
Conditions
Labor
Interventions
peanut shaped birthing ball
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 17, 2022 · Synced Sep 26, 2026, 10:47 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Management of Postoperative Pain With Preemptive Analgesia in Cesarean Section

NCT02879435
View directory record Official record
Conditions
Labor Pain
Interventions
Bupivacaine, Placebo
Drug · Other
Lead sponsor
Mark Kosanovich
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 24, 2016 · Synced Sep 26, 2026, 10:47 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

The Impact of Needle Manipulation and Accuracy Between Hand Held Automatic and Traditional Ultrasound Device

NCT05909085
View directory record Official record
Conditions
Labor Analgesia
Interventions
Traditional ultrasound, Automated ultrasound
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Sep 26, 2026, 10:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Optimizing Dose of Bupivacaine in Combined Spinal Epidurals To Reduce Side Effects

NCT02159807
View directory record Official record
Conditions
Pregnancy
Interventions
Bupivacaine, Fentanyl
Drug
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 48 Years · Female only
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 2, 2019 · Synced Sep 26, 2026, 10:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

High Protein Intake to Decrease Emesis and Promote Patient Satisfaction in Labor

NCT01414478
View directory record Official record
Conditions
Emesis
Interventions
Protein Shake
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
14 Years to 50 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 3, 2013 · Synced Sep 26, 2026, 10:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Virtual Reality Compared to Nitrous Oxide for Labor Analgesia

NCT04749043
View directory record Official record
Conditions
Labor Pain
Interventions
Oculus Quest 2 Virtual Reality Device, Nitrous oxide
Device · Drug
Lead sponsor
Brendan Carvalho
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Mar 17, 2024 · Synced Sep 26, 2026, 10:47 PM EDT
Terminated Phase 4 Interventional Results available

PIEB vs CEI for Labor Analgesia: An MLAC Study

NCT02573597
View directory record Official record
Conditions
Pregnancy
Interventions
Bupivacaine, Sufentanil
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 17, 2022 · Synced Sep 26, 2026, 10:47 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Prospective Effect of Intravenous Ketorolac on Opioid Use, EBL and Complications Following Cesarean Delivery

NCT02509312
View directory record Official record
Conditions
Analgesia, Obstetrical, Postpartum Hemorrhage, Opioid Use, Nonsteroidals (NSAIDs)Toxicity, Coagulation Defect; Postpartum, Postoperative Pain, Ketorolac Adverse Reaction, Blood Loss, Postoperative
Interventions
Ketorolac, Placebo
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 6, 2022 · Synced Sep 26, 2026, 10:47 PM EDT
Completed Not applicable Interventional Results available

Presence of a Companion During Performance of Neuraxial Labor Analgesia

NCT02982213
View directory record Official record
Conditions
Anxiety, Pain, Health Knowledge, Attitudes, Practice
Interventions
Companion Present
Other
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 11, 2021 · Synced Sep 26, 2026, 10:47 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

DPE Technique in Labor Epidural for Morbidly Obese Women

NCT03074695
View directory record Official record
Conditions
Morbid Obesity, Labor Pain
Interventions
Dural puncture epidural (DPE), Standard Epidural (EPL), Dural puncture epidural (DPE), Standard Epidural (EPL)
Procedure · Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 42 Years · Female only
Enrollment
141 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated May 31, 2022 · Synced Sep 26, 2026, 10:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Music and/or Video Games During Labor

NCT03024411
View directory record Official record
Conditions
Labor Pain
Interventions
iPod (Music/video games)
Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years and older · Female only
Enrollment
253 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 7, 2018 · Synced Sep 26, 2026, 10:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Programmed Intermittent Epidural Bolus Time Interval and Injection Volume

NCT00417027
View directory record Official record
Conditions
Labor Pain
Interventions
Programmed Intermittent Epidural Bolus (PIEB)
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
190 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 13, 2014 · Synced Sep 26, 2026, 10:47 PM EDT
Terminated Phase 4 Interventional Results available

Tetracaine Combined Spinal Epidural (CSE) Versus Bupivacaine CSE

NCT01005459
View directory record Official record
Conditions
Labor Pain
Interventions
Tetracaine, Bupivacaine
Drug
Lead sponsor
Wake Forest University
Other
Eligibility
12 Years and older · Female only
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 7, 2017 · Synced Sep 26, 2026, 10:47 PM EDT
Completed Not applicable Interventional Results available

Pulse Pressure and Post-epidural Fetal Heart Rate Changes

NCT02565485
View directory record Official record
Conditions
Fetus or Neonate Affected by Maternal Epidural Anesthesia During Labor and Delivery
Interventions
Lactated Ringer's
Drug
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
276 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 8, 2018 · Synced Sep 26, 2026, 10:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Neuraxial Analgesia on Maternal Breastfeeding

NCT01074190
View directory record Official record
Conditions
Pain, Breastfeeding
Interventions
Group 1, Group 2, Group 3
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Female only
Enrollment
345 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 4, 2022 · Synced Sep 26, 2026, 10:47 PM EDT
Terminated Not applicable Interventional Results available

3D Ultrasound-guided Labor Epidural Analgesia in the Morbid Obese Parturient

NCT03405311
View directory record Official record
Conditions
Obesity, Morbid, Pregnancy, Pain
Interventions
Rivanna Accuro 3D Ultrasound Device, Palpation
Device · Other
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 26, 2026, 10:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of Extended-Release Liposomal Bupivacaine for Post-Partum Pain Management Following Obstetrical Laceration

NCT03152877
View directory record Official record
Conditions
Pain, Obstetric
Interventions
Bupivacaine Liposome Injectable Product, 0.25% plain bupivacaine
Drug
Lead sponsor
Walter Reed National Military Medical Center
Federal
Eligibility
18 Years to 55 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 14, 2019 · Synced Sep 26, 2026, 10:47 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

The Effects of Combined Spinal Epidurals on Fever During Labor of First-Time Mothers

NCT00802646
View directory record Official record
Conditions
Vaginal Delivery
Interventions
saline, fentanyl/bupivacaine/epinephrine
Drug
Lead sponsor
Ochsner Health System
Other
Eligibility
18 Years to 34 Years · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 11, 2023 · Synced Sep 26, 2026, 10:47 PM EDT
Completed Phase 4 Interventional Results available

Comparison of Epidural Fentanyl and Clonidine for Breakthrough Pain

NCT01846221
View directory record Official record
Conditions
Labor Pain
Interventions
Clonidine, Fentanyl
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older · Female only
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 2, 2018 · Synced Sep 26, 2026, 10:47 PM EDT
Recruiting Phase 3 Interventional

Ropivacaine and Fentanyl for Labor Epidural Initiation

NCT07076368
View directory record Official record
Conditions
Pregnancy, Labor and Delivery, Labor Analgesia
Interventions
Ropivacaine + Fentanyl
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 26, 2026 · Synced Sep 26, 2026, 10:47 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Mu-Opioid Receptor Genetic Polymorphism and Intrathecal Analgesia

NCT00418015
View directory record Official record
Conditions
Labor Pain, Post-cesarean Delivery
Interventions
Blood Draw
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
293 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 13, 2014 · Synced Sep 26, 2026, 10:47 PM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Effect of Epidural Analgesia During Labor on Force of Maternal Push

NCT04888858
View directory record Official record
Conditions
Labor Pain, Analgesia, Maternal; Procedure
Interventions
Epidural analgesia (0.125% bupivacaine/2mcg fentanyl solution)
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 24, 2023 · Synced Sep 26, 2026, 10:47 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Optimal Bupivacaine Dose for Initiation of Labor Epidural Techniques

NCT04814537
View directory record Official record
Conditions
Labor Pain, Analgesia
Interventions
Bupivacaine Hydrochloride
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Sep 26, 2026, 10:47 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of Analgesic Techniques on Duration of Labor for Induction Patients

NCT01982851
View directory record Official record
Conditions
Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
Interventions
Epidural de novo, CSE
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
134 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 10, 2014 · Synced Sep 26, 2026, 10:47 PM EDT