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ClinicalTrials.gov public records Last synced Oct 21, 2026, 3:46 AM EDT

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Showing 1–24 of 448 matching trials from the live ClinicalTrials.gov search.
Conditions
Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Injuries
Interventions
Self-guided pre-habilitation exercise program, Traditional pre-habilitation
Other
Lead sponsor
WellSpan Health
Other
Eligibility
13 Years to 50 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
York, Pennsylvania
Conditions
Dry Eye Disease
Interventions
ABBV-444, REFRESH OPTIVE UD
Drug
Lead sponsor
AbbVie
Industry
Eligibility
18 Years and older
Enrollment
261 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
20
States / cities
Dothan, Alabama • Chandler, Arizona • Azusa, California + 16 more
Conditions
Anterior Cruciate Ligament (ACL) Tear
Interventions
Not listed
Lead sponsor
Arthroresearch LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Conditions
Keratoconjunctivitis Sicca
Interventions
Retaine™
Drug
Lead sponsor
Ocusoft, Inc.
Industry
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Andover, Massachusetts
Conditions
Rupture of Anterior Cruciate Ligament, Tear of Anterior Cruciate Ligament
Interventions
Mepivacaine, adductor canal continuous nerve catheter, Normal Saline as bolus followed by bupivacaine, adductor canal nerve block, ropivacaine and dexamethasone, Propofol, Fentanyl
Drug · Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
14 Years and older
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Full-thickness Rotator Cuff Tear
Interventions
Repair with DAA (dermal allograft augmentation)
Device
Lead sponsor
Arthrex, Inc.
Industry
Eligibility
30 Years to 75 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
4
States / cities
Scottsdale, Arizona • Greenwich, Connecticut • Medford, Oregon + 1 more
Completed Not applicable Interventional Results available

Impact of Humeral Component Version on Outcomes Following RTSA

NCT03111147
Conditions
Rotator Cuff Tear Arthropathy
Interventions
0 degrees humeral component version, 30 degrees humeral component retroversion
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Royal Oak, Michigan
Withdrawn Not applicable Interventional Accepts healthy volunteers

Ultrasound for Rectus Femoris Measurement

NCT04105816
Conditions
Muscle Atrophy, Proximal, Muscle Atrophy, ACL Tear, Quadriceps Muscle Atrophy
Interventions
892.1550 Ultrasonic pulsed doppler imaging system, Thigh circumference measurement
Device · Diagnostic Test
Lead sponsor
Robert Westermann
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Active, not recruiting Not applicable Interventional

Bridge-Enhanced ACL Repair-Safety Study (BEAR Trial)

NCT02292004
Conditions
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Tear
Interventions
ACL Repair with MIACH Scaffold, Standard ACL Reconstruction
Device · Procedure
Lead sponsor
Miach Orthopaedics
Industry
Eligibility
18 Years to 35 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Phase 4 Interventional Results available

Effects of NOV03 on the Tear Film

NCT05723770
Conditions
Dry Eye Disease (DED)
Interventions
instillation of NOV03
Drug
Lead sponsor
Bausch & Lomb Incorporated
Industry
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Miami, Florida
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Will a Hands on Technique Applied to the Face Increase the Tear Production in Participants

NCT07632183
Conditions
Increased Production of Tears
Interventions
sphenopalatine ganglion release
Procedure
Lead sponsor
Edward Via Virginia College of Osteopathic Medicine
Other
Eligibility
18 Years to 45 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Spartanburg, South Carolina
Conditions
Dry Eye Disease
Interventions
Systane Ultra, Saline solution, Maxidex
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
New York, New York
Conditions
Meniscal Degeneration, Osteoarthritis, Knee
Interventions
TeMPO Home Exercise Program, Motivational SMS Messages, In-Clinic Topical Therapy, In-Clinic Exercise Therapy
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
45 Years to 85 Years
Enrollment
879 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
4
States / cities
Boston, Massachusetts • Buffalo, New York • Cleveland, Ohio + 1 more
Completed Phase 3 Interventional Accepts healthy volunteers

Promoting Effective Recovery From Labor Urinary Incontinence (PERL)

NCT00506116
Conditions
Urinary Incontinence, Pelvic Organ Prolapse, Perinatal Laceration, Second Stage Labor
Interventions
Videotape, routine care, PME instruction, PME practice and record keeping (in diaries), Non-directed or directed,spontaneous or sustained pushing, Data collection
Behavioral · Procedure
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1996 – 2006
U.S. locations
1
States / cities
Ann Arbor, Michigan
Conditions
Dry Eye Disease
Interventions
P-321 Ophthalmic Solution, P-321 Ophthalmic Solution placebo
Drug
Lead sponsor
Parion Sciences
Industry
Eligibility
18 Years to 80 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Plantation, Florida
Conditions
Bone Diseases, Infectious, Musculoskeletal Diseases, Joint Diseases, Osteoarthritis, ACL Tear, Cartilage Degeneration
Interventions
MRI
Diagnostic Test
Lead sponsor
Xiaojuan Li
Other
Eligibility
18 Years to 50 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Conditions
Breast Cancer, Ovarian Cancer, Pancreatic Cancer, Prostate Cancer, Melanoma
Interventions
Schirmer strip, a Class I Medical Device typically used to test for dry eye.
Other
Lead sponsor
Namida Lab
Industry
Eligibility
18 Years to 100 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Fayetteville, Arkansas
Not listed Not applicable Interventional Accepts healthy volunteers

Nanoscope Cost Analysis Study

NCT06603740
Conditions
Meniscal Tear
Interventions
Arthrex Nanoscope, Conventional Arthroscopy without Arthrex Nanoscope
Device
Lead sponsor
Arthrex, Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Warwick, Rhode Island
Conditions
Anterior Cruciate Ligament Tear, Knee Meniscus Tear
Interventions
Femoral Nerve Block, Adductor Canal Nerve Block, preoperative Femoral Nerve Block using 20ml of 0.5% ropivacaine, Preoperative Adductor canal block with 0.75%% ropivacaine 13.3ml.
Procedure · Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
San Francisco, California
Conditions
Meniscus Tear
Interventions
Transtibial pullout technique
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
2
States / cities
Rochester, Minnesota • Columbia, Missouri
Completed No phase listed Observational Accepts healthy volunteers

Analysis of Cataract Surgery Induced Dry Eye

NCT01471561
Conditions
Cataract
Interventions
Not listed
Lead sponsor
TearLab Corporation
Industry
Eligibility
18 Years and older
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
4
States / cities
Miami, Florida • Minneapolis, Minnesota • New York, New York + 1 more
Conditions
Rotator Cuff Tear
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 100 Years
Enrollment
452 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2024
U.S. locations
9
States / cities
San Francisco, California • Boulder, Colorado • Iowa City, Iowa + 6 more
Conditions
Reverse Total Shoulder Arthroplasty, Rotator Cuff Tear Arthropathy, Advanced Glenohumeral Osteoarthritis
Interventions
Pectoralis Minor Release, RSA
Procedure
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Atlanta, Georgia
Completed Not applicable Interventional Accepts healthy volunteers

Closed Eye Neutrophils in Dry Eye Disease

NCT03332342
Conditions
Dry Eye, Ocular Inflammation
Interventions
Eye wash
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Birmingham, Alabama