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Showing 697–720 of 725 matching trials from the live ClinicalTrials.gov search.
Conditions
Stroke, Aphasia Following Cerebral Infarction, Hemiparesis After Stroke
Interventions
CARAT: combined aphasia and robot-assisted arm therapy, Robot-assisted arm therapy
Behavioral
Lead sponsor
New York Medical College
Other
Eligibility
18 Years to 90 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Valhalla, New York
Conditions
Anarthria, Dysarthria, Tetraplegia, Spinal Cord Injuries, Amyotrophic Lateral Sclerosis, Brain Stem Infarctions, Locked in Syndrome, Muscular Dystrophies
Interventions
BrainGate Neural Interface System
Device
Lead sponsor
Leigh R. Hochberg, MD, PhD.
Other
Eligibility
18 Years to 80 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Stanford, California • Boston, Massachusetts
Conditions
Post-Stroke Chronic Aphasia
Interventions
Semantic Feature Ecological Momentary Intervention
Behavioral
Lead sponsor
Northeastern University
Other
Eligibility
18 Years to 89 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Recruiting Not applicable Interventional Accepts healthy volunteers

Neuroimaging Reveals Treatment-related Changes in DLD

NCT05268341
Conditions
Developmental Language Disorder
Interventions
My Sentence Builder
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
48 Months to 71 Months
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
6
States / cities
Cincinati, Ohio • Cincinnati, Ohio
Active, not recruiting No phase listed Observational Accepts healthy volunteers

OpenEvidence Safety and Comparative Efficacy of Four LLM's in Clinical Practice

NCT07199231
Conditions
AI (Artificial Intelligence), Large Language Model, Generative Artificial Intelligence
Interventions
AI clinical reference tool
Other
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Cambridge, Massachusetts
Recruiting Not applicable Interventional Accepts healthy volunteers

Combined Oral Motor Stimulation and Language on Preterm Infant Feeding

NCT05861531
Conditions
Language Delay, Language Development, Feeding; Difficult, Newborn, Mother-Infant Interaction, Maternal Behavior
Interventions
Oromotor stimulation, Reading curriculum, LENA recording, LENA linguistic feedback, No oromotor stimulation
Behavioral
Lead sponsor
Women and Infants Hospital of Rhode Island
Other
Eligibility
23 Weeks to 30 Weeks
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Providence, Rhode Island
Completed No phase listed Observational Accepts healthy volunteers

Participant Database for Autism Research Studies

NCT00549731
Conditions
Autism Spectrum Disorder
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
14 Years to 32 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2023
U.S. locations
1
States / cities
Charlestown, Massachusetts
Conditions
Obsessive-compulsive Disorder, Social Phobia, Generalized Anxiety Disorder, Specific Phobia, Separation Anxiety Disorder, Selective Mutism, Anxiety Disorder, Not Otherwise Specified
Interventions
Parent-Led Exposure Therapy, Treatment As Usual
Behavioral · Other
Lead sponsor
University of South Florida
Other
Eligibility
3 Years to 7 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
St. Petersburg, Florida
Conditions
Dyslexia, Reading Disability
Interventions
Active transcranial electrical stimulation (tES), Sham transcranial electrical stimulation (tES)
Device
Lead sponsor
General Neuro Inc.
Industry
Eligibility
7 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Phase 1Phase 2 Interventional Results available

Treating Intention In Aphasia: Neuroplastic Substrates

NCT00567242
Conditions
Aphasia, Cerebrovascular Accident
Interventions
Word-finding with intention component, Word-finding with no intention component
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 95 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
3
States / cities
Gainesville, Florida • Jacksonville, Florida
Conditions
Eye Disorders, Cataract Extraction, Cataract and IOL Surgery, Cataract Surgery Experience, Cataract Surgery, Intraocular Lens
Interventions
LLM-based Education
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Ovarian Cancer
Interventions
Shared Medical Decision Tool, Engaging Patients in Decision Making, Literacy Spanish Language
Other · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Houston, Texas
Completed Not applicable Interventional Accepts healthy volunteers Results available

English as a Second Language Health Literacy Program

NCT04125680
Conditions
Health Literacy, Language
Interventions
ESL Health Literacy Classes
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 100 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Flint, Michigan
Completed Not applicable Interventional Results available

Speech Therapy for Aphasia: Comparing Two Treatments

NCT02153710
Conditions
Stroke
Interventions
Semantic Feature Analysis therapy, Phonomotor Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Seattle, Washington
Terminated No phase listed Observational Accepts healthy volunteers

Central Mechanisms in Speech Motor Control Studied With H215O PET

NCT00001308
Conditions
Communication Disorder, Healthy, Stuttering, Tourette Syndrome, Voice Disorder
Interventions
Not listed
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
18 Years to 85 Years
Enrollment
1,163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1992 – 2016
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Autism Spectrum Disorder (ASD), Autism
Interventions
Early Start Denver Model (ESDM), Pivotal Response Treatment (PRT), Developmental Reciprocity Treatment (DRT)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
2 Years to 4 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2037
U.S. locations
1
States / cities
Palo Alto, California
Conditions
Aphasia, Aphasia Following Cerebral Infarction, Aphasia, Acquired, Aphasia, Rehabilitation, Aphasia, Anomic, Aphasia, Broca, Aphasia, Conduction, Aphasia, Expressive, Aphasia Non Fluent, Aphasia, Mixed
Interventions
Semantic Feature Analysis (traditional), Semantic Feature Analysis + Metacognitive Strategy Training
Behavioral
Lead sponsor
Teachers College, Columbia University
Other
Eligibility
18 Years to 89 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Thirty Million Words-Early Childhood Educator (TMW-ECE)

NCT04027673
Conditions
Language Development
Interventions
TMW ECE Curriculum
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
432 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Completed Phase 2 Interventional Results available

Brain Stimulation and Aphasia Treatment

NCT01686373
Conditions
Aphasia
Interventions
Activa Dose II Real tDCS, Activa Dose II Sham tDCS
Device
Lead sponsor
University of South Carolina
Other
Eligibility
25 Years to 80 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
2
States / cities
Charleston, South Carolina • Columbia, South Carolina
Conditions
Aphasia
Interventions
Choir singing, Usual care
Behavioral · Other
Lead sponsor
University of Ottawa
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Primary Progressive Aphasia(PPA), Semantic Dementia, Logopenic Progressive Aphasia (LPA), Nonfluent Aphasia, Progressive, Progressive Aphasia, Semantic Variant Primary Progressive Aphasia (svPPA), Semantic Aphasia, Logopenic Variant Primary Progressive Aphasia, Logopenic Variant of Primary Progressive Aphasia (LPA), Logopenic Progressive Aphasia, Nonfluent Variant Primary Progressive Aphasia (nfvPPA), Nonfluent Progressive Aphasia
Interventions
Multicomponent Lexical Retrieval Cascade Training, Multicomponent Video Implemented Script Training in Aphasia
Behavioral
Lead sponsor
Maya Henry
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Austin, Texas
Conditions
Dementia Severe
Interventions
AMUSED, Reading Aloud
Behavioral
Lead sponsor
Alaine E Hernandez, PhD
Other
Eligibility
65 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
8
States / cities
Cynthiana, Kentucky • Danville, Kentucky • Lexington, Kentucky + 3 more
Conditions
Aphasia
Interventions
Abstract Semantic Association Network Training (AbSANT)
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
Not listed
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Hershey, Pennsylvania
Conditions
Mild Cognitive Impairment, Primary Progressive Aphasia, Dementia
Interventions
Computerized Cognitive Training, Active tDCS (tDCS) on DLPFC
Other · Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years to 90 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland