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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Language Development Disorders Clear all
Active, not recruiting Phase 2 Interventional

Early Treatment of Language Impairment in Young Children With Autism Spectrum Disorder With Leucovorin Calcium

NCT04060017
View directory record Official record
Conditions
Autism Spectrum Disorder, Language Disorders
Interventions
Levoleucovorin Calcium, Placebo
Drug · Other
Lead sponsor
Southwest Autism Research & Resource Center
Other
Eligibility
30 Months to 60 Months
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
2
States / cities
Phoenix, Arizona • Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Sep 3, 2026, 1:19 AM EDT
Not listed Not applicable Interventional

Using fMRI to Evaluate Instructional Programs for Children With Developmental Dyslexia

NCT00068835
View directory record Official record
Conditions
Developmental Dyslexia
Interventions
Lindamood-Bell training for dyslexia
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
8 Years to 12 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2005
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Sep 3, 2026, 1:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Promoting Early School Readiness in Primary Health Care

NCT00212576
View directory record Official record
Conditions
Language Development Disorders
Interventions
Video Interaction Project, Building Blocks Project
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
35 Weeks and older
Enrollment
675 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 28, 2019 · Synced Sep 3, 2026, 1:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Framework For Linking Sequential Pattern Rules in DLD: Perception in Toddlers

NCT04531514
View directory record Official record
Conditions
Developmental Language Disorder, Speech Sound Disorder, Specific Language Impairment
Interventions
Sensitivity to phonological rules & referents OR: Toddlers, Sensitivity to phonological rules & referents FR: Toddlers
Other
Lead sponsor
Father Flanagan's Boys' Home
Other
Eligibility
19 Months to 36 Months
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Sep 3, 2026, 1:19 AM EDT
Recruiting No phase listed Observational

FOXP1 Syndrome: The Seaver Autism Center for Research and Treatment is Characterizing FOXP1-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.

NCT03718923
View directory record Official record
Conditions
FOXP1, Mental Retardation With Language Impairment and With or Without Autistic Features, Autism Spectrum Disorder
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
2 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 3, 2026, 1:19 AM EDT
Completed Not applicable Interventional

Pivotal Response Treatment for Individuals With Intellectual Disabilities

NCT01988623
View directory record Official record
Conditions
Intellectual Disabilities, Speech Delay, Language Disorder
Interventions
Pivotal Response Treatment (PRT)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
2 Years to 17 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Sep 3, 2026, 1:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Social Skills in Children With ASD and Process Drama

NCT02850666
View directory record Official record
Conditions
Autistic Disorder
Interventions
Interdisciplinary process drama
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
3 Years to 4 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 14, 2018 · Synced Sep 3, 2026, 1:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Parent-Level Predictors of Early Language Interaction Quality and Intervention Outcomes

NCT03525951
View directory record Official record
Conditions
Language Development Disorders, Autism Spectrum Disorder
Interventions
Enhanced Milieu Teaching, no intervention comparison group
Behavioral · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
30 Months and older
Enrollment
156 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Sep 3, 2026, 1:19 AM EDT
Completed Not applicable Interventional

Telehealth Parent-Implemented Intervention for Young Children With Autism Spectrum Disorder (ASD)

NCT05176808
View directory record Official record
Conditions
Autism Spectrum Disorder, Autistic Disorder, Active Autistic Disorder, Autism, Asperger Syndrome, PDD-NOS, Social Communication Delay, Mixed Expressive Receptive Language Disorder, Other Symbolic Dysfunctions
Interventions
Early Achievements- Parent Coaching Intervention
Behavioral
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
18 Months to 42 Months
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Sep 3, 2026, 1:19 AM EDT
Completed Not applicable Interventional

Proactive Speech and Language Intervention for Infants With Down Syndrome

NCT06450509
View directory record Official record
Conditions
Down Syndrome
Interventions
Babble Boot Camp
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
0 Months to 12 Months
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Sep 3, 2026, 1:19 AM EDT
Terminated No phase listed Observational

Hereditary Deficits in Auditory Processing Leading to Language Impairment

NCT00004570
View directory record Official record
Conditions
Auditory Perceptual Disorder, Language Delay, Language Disorder
Interventions
Not listed
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
6 Years to 85 Years
Enrollment
875 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 19, 2018 · Synced Sep 3, 2026, 1:19 AM EDT
Recruiting Not applicable Interventional

Training Caregivers to Teach Vocabulary to Children With Language Impairment

NCT07519629
View directory record Official record
Conditions
Developmental Language Disorder
Interventions
Robust vocabulary intervention
Behavioral
Lead sponsor
Northern Arizona University
Other
Eligibility
4 Years to 6 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Flagstaff, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Sep 3, 2026, 1:19 AM EDT
Terminated Phase 2 Interventional Results available

A Trial of the Drug Donepezil for Sleep Enhancement and Behavioral Change in Children With Autism

NCT01887132
View directory record Official record
Conditions
Autism Spectrum Disorders
Interventions
Donepezil, Placebo
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
24 Months to 50 Months
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 24, 2017 · Synced Sep 3, 2026, 1:19 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Development of Normative Ultrasound Databases of Tongue Surface Configuration

NCT00001218
View directory record Official record
Conditions
Healthy, Speech Disorders
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
Not listed
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1987 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Sep 3, 2026, 1:19 AM EDT
Not yet recruiting Not applicable Interventional

Trial of Center-Based Early Start Denver Model vs. Pivotal Response Treatment in Children With Autism

NCT07522190
View directory record Official record
Conditions
Autism Spectrum Disorder (ASD), Autism
Interventions
Early Start Denver Model (ESDM), Pivotal Response Treatment (PRT), Developmental Reciprocity Treatment (DRT)
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
2 Years to 4 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2037
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Sep 3, 2026, 1:19 AM EDT
Recruiting Not applicable Interventional

Treating Complex Grammar Knowledge Deficits in School-Age Children With Developmental Language Disorder

NCT06911138
View directory record Official record
Conditions
Developmental Language Disorders
Interventions
Behavorial
Behavioral
Lead sponsor
Ohio University
Other
Eligibility
8 Years to 11 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
4
States / cities
Tucson, Arizona • Athens, Ohio • Logan, Utah + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 3, 2025 · Synced Sep 3, 2026, 1:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Maximizing Language Development in Children With Hearing Loss

NCT01963468
View directory record Official record
Conditions
Hearing Loss
Interventions
Early language intervention
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
6 Months to 18 Months
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Evanston, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 28, 2018 · Synced Sep 3, 2026, 1:19 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sentence Prediction in Developmental Language Disorder

NCT07510854
View directory record Official record
Conditions
Developmental Language Disorder
Interventions
Thematic role, Sentence complexity
Behavioral
Lead sponsor
Father Flanagan's Boys' Home
Other
Eligibility
5 Years to 7 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Sep 3, 2026, 1:19 AM EDT
Completed Not applicable Interventional

Stimulus-Stimulus Pairing Study

NCT02464527
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Stimulus-stimulus pairing, Vocal recorder
Behavioral · Other
Lead sponsor
Emory University
Other
Eligibility
24 Months to 47 Months
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 14, 2016 · Synced Sep 3, 2026, 1:19 AM EDT
Completed Not applicable Interventional

A Randomized Clinical Trial for Toddlers With ASD

NCT01008800
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Social communication
Behavioral
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
22 Months to 33 Months
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 9, 2021 · Synced Sep 3, 2026, 1:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Phonotactic Probability and Orthography on Vocabulary Learning

NCT06935851
View directory record Official record
Conditions
DLD
Interventions
VOCAB +
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
8 Years to 9 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 3, 2026, 1:19 AM EDT
Completed Not applicable Interventional

Effects of TBS on Reading in Adult Struggling Readers

NCT04041960
View directory record Official record
Conditions
Developmental Reading Disorder, Dyslexia, Developmental
Interventions
Transcranial magnetic stimulation (TMS)
Other
Lead sponsor
Georgia State University
Other
Eligibility
18 Years to 50 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 15, 2021 · Synced Sep 3, 2026, 1:19 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Neural Mechanisms of Successful Intervention in Children With Dyslexia

NCT04323488
View directory record Official record
Conditions
Dyslexia, Developmental
Interventions
Lindamood-Bell Seeing Stars
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
8 Years to 12 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Sep 3, 2026, 1:19 AM EDT
Completed Not applicable Interventional

Adapting BA for Minimally Verbal Autistic Adults

NCT06064422
View directory record Official record
Conditions
Autism, Depression, Autism Spectrum Disorder With Impaired Functional Language, Autism Spectrum Disorder
Interventions
BeatIt-MV
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Sep 3, 2026, 1:19 AM EDT