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Showing 25–48 of 171 matching trials from the live ClinicalTrials.gov search.
Completed Phase 2 Interventional Results available

AFQ056 for Language Learning in Children With FXS

NCT02920892
Conditions
Fragile X Syndrome
Interventions
AFQ056, Placebo, Language Intervention
Drug · Other
Lead sponsor
Elizabeth Berry-Kravis
Other
Eligibility
32 Months to 6 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
14
States / cities
Davis, California • Denver, Colorado • New Haven, Connecticut + 11 more
Conditions
Developmental Language Disorders
Interventions
Grammar Treatment
Behavioral
Lead sponsor
Ohio University
Other
Eligibility
8 Years to 11 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
4
States / cities
Tucson, Arizona • Athens, Ohio • Logan, Utah + 1 more
Conditions
Joint Engagement + Enhanced Milieu Training, Joint Engagement + Enhanced Milieu Training+Augmentative Communication (AAC)
Interventions
JAE Intervention
Behavioral
Lead sponsor
Autism Speaks
Other
Eligibility
5 Years to 8 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
3
States / cities
Los Angeles, California • Baltimore, Maryland • Nashville, Tennessee
Recruiting Not applicable Interventional Accepts healthy volunteers

Rural Autistic Individuals - Supporting Expression

NCT07054866
Conditions
Autism Disorder, Language Development Disorders, ADHD, Typical Development, Rural Health, Children, Neuroimaging, Eye Tracking, EEG, fNIRS
Interventions
Speech-Gesture combinations
Behavioral
Lead sponsor
Montana State University
Other
Eligibility
2 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Bozeman, Montana
Recruiting No phase listed Observational Accepts healthy volunteers

The Development of Stuttering in Young Children

NCT06578416
Conditions
Stuttering, Stuttering, Childhood, Stuttering, Developmental
Interventions
Standardized assessments of speech and language abilities
Diagnostic Test
Lead sponsor
Michigan State University
Other
Eligibility
3 Years to 6 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
East Lansing, Michigan
Completed Not applicable Interventional Accepts healthy volunteers

Age-related Correlates of Treatment for Late-acquired Sounds

NCT03663972
Conditions
Speech Sound Disorder, Phonology Disorder, Phonology Impairment, Phonological Disorder, Articulation Disorders in Children, Developmental Phonological Disorder, Speech Disorders, Speech Delay, Articulation Disorders, Developmental
Interventions
articulation therapy, phonologic treatment
Behavioral
Lead sponsor
University of Wyoming
Other
Eligibility
4 Years to 8 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Laramie, Wyoming
Completed Not applicable Interventional Accepts healthy volunteers

A Framework For Linking Sequential Pattern Rules in DLD: Perception in Adults

NCT04996472
Conditions
Developmental Language Disorder, Speech Sound Disorder, Specific Language Impairment
Interventions
Sensitivity to phonological rules: Adults, Sensitivity to semantic category cues: Adults
Behavioral
Lead sponsor
Father Flanagan's Boys' Home
Other
Eligibility
18 Years to 30 Years
Enrollment
933 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
2
States / cities
Tucson, Arizona • Omaha, Nebraska
Conditions
Central Auditory Processing Disorder, Hearing Impaired (Partially), Hearing, Hearing Abnormality, Hearing Disability, Hearing Disorder, Hearing Disorders, Hearing Impairment, Sensorineural, Hearing Handicap, Hearing Impaired, Hearing Impairment, Hearing Loss, Central Auditory Disease, Noise Exposure, Noise Induced Hearing Loss, Noise-Induced Hearing Loss, Sound Perception, Myelin Degeneration, Myelinopathy, Myelin Integrity, Remyelination, Hidden Hearing Loss, Cocktail Party Skill, Cocktail Party Syndrome, CAPD, Age Problem
Interventions
Clemastine Fumarate Combined With Engineered Sound, Clemastine Fumarate Combined With Pink Noise, Placebo Drug With Engineered Sound, Placebo - Placebo
Combination Product · Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
45 Years to 65 Years
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Conditions
Down Syndrome
Interventions
Linguistic simplification
Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
2 Years to 7 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
East Lansing, Michigan
Recruiting Not applicable Interventional Accepts healthy volunteers

Exercise Training in Children With Communication Impairments

NCT06340893
Conditions
Developmental Language Disorder
Interventions
Exercise, Restful Play
Behavioral
Lead sponsor
Marquette University
Other
Eligibility
5 Years to 9 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Completed Not applicable Interventional Accepts healthy volunteers

Promoting Early School Readiness in Primary Health Care

NCT00212576
Conditions
Language Development Disorders
Interventions
Video Interaction Project, Building Blocks Project
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
35 Weeks and older
Enrollment
675 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2017
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Social Cognitive Development in Young Children With Autism

NCT01425918
Conditions
Autism Spectrum Disorder
Interventions
Social Enhancement Intervention, Parent Education
Behavioral
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
24 Months to 42 Months
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Autism Spectrum Disorder
Interventions
Stay-Play-Talk Basic, Stay-Play-Talk Plus, Stay-Play-Talk Advanced
Behavioral
Lead sponsor
University of Kansas
Other
Eligibility
3 Years to 6 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
2
States / cities
Kansas City, Kansas • Chapel Hill, North Carolina
Conditions
Autism Spectrum Disorder, Depression - Major Depressive Disorder, Anxiety, Generalized, Bipolar Disorder (BD), Attention Deficit Hyperactivity Disorder (ADHD), Schizophrenia Spectrum &Amp; Other Psychotic Disorders, Post Traumatic Stress Disorder, Obsessive Compulsive Disorder (OCD)
Interventions
Solicue Machine Learning Models, Mercuria Machine Learning Models
Diagnostic Test
Lead sponsor
Psyrin Inc.
Industry
Eligibility
13 Years to 60 Years
Enrollment
500 participants
Timeline
2025 – 2026
U.S. locations
2
States / cities
Brookline, Massachusetts • Zanesville, Ohio
Conditions
Autism Spectrum Disorder (ASD), Central Auditory Processing Disorder, Nervous System Disorder, Neurological Disorder
Interventions
Audio fairy tales
Behavioral
Lead sponsor
Natalia Poluektova
Other
Eligibility
3 Years to 70 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
New York, New York
Conditions
Speech and Language Disorder, Cerebral Palsy, Hemiplegia, Hemiparesis
Interventions
Speech-language therapy (SLT), Modified constraint-induced movement therapy (mCIMT)
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
15 Months to 7 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Chicago, Illinois
Recruiting Not applicable Interventional Accepts healthy volunteers

Word Learning From Parentese in Autistic Children

NCT06649916
Conditions
Autism, Autism Spectrum Disorder, Neurodevelopmental Disorders
Interventions
Parentese Speech, Adult Registered Speech
Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Months to 59 Months
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Richardson, Texas
Conditions
Autism, Depression, Autism Spectrum Disorder With Impaired Functional Language, Autism Spectrum Disorder
Interventions
BeatIt-MV
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Piscataway, New Jersey
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Spectacle Prescribing in Early Childhood

NCT04728451
Conditions
Astigmatism Bilateral, Eyeglasses
Interventions
Spectacle wear support, Spectacles
Behavioral · Device
Lead sponsor
University of Arizona
Other
Eligibility
12 Months to 35 Months
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Tucson, Arizona
Conditions
Infant Development, Language Development, Prematurity, Stress
Interventions
Music, Music and parent voice, Standard Care
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
24 Weeks to 30 Weeks
Enrollment
243 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
2
States / cities
New Haven, Connecticut • Boston, Massachusetts
Conditions
Developmental Delays
Interventions
Therapist-Delivered Early Intervention Approach, Caregiver Coaching Early Intervention Approach, Parents Taking Action
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
12 Months to 32 Months
Enrollment
1,269 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Evanston, Illinois
Conditions
Ovarian Cancer
Interventions
Shared Medical Decision Tool, Engaging Patients in Decision Making, Literacy Spanish Language
Other · Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Houston, Texas
Conditions
Autism Spectrum Disorder, Language Disorders
Interventions
Levoleucovorin Calcium, Placebo
Drug · Other
Lead sponsor
Southwest Autism Research & Resource Center
Other
Eligibility
30 Months to 60 Months
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
2
States / cities
Phoenix, Arizona • Brooklyn, New York
Conditions
Stuttering
Interventions
Asenapine
Drug
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 70 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Orange, California